Panthers vs. 49ers
FREE NFL AI Predictions
November 24, 2025



Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 24, 2025

Start Time: 8:15 PM EST​

Venue: ​

49ers Record:

Panthers Record:

OPENING ODDS

CAR Moneyline:

SF Moneyline:

CAR Spread: 0

SF Spread:

Over/Under:

CAR
Betting Trends

SF
Betting Trends

MATCHUP TRENDS

CAR vs. SF
Best Prop Bet

LIVE NFL ODDS

NFL ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
295-209
VAULT
NET UNITS
(INCL VIG)
+417.7
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
EXECUTIVE
VS. SPREAD
1519-1315
EXECUTIVE
NET UNITS
(INCL VIG)
+312.6
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$31,258

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Carolina vs San Francisco AI Prediction:
Free NFL Betting Insights for 11/24/25

Panthers AI Preview

 Carolina vs San Francisco AI Prediction: Free NFL Betting Insights for Nov 24. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

49ers AI Preview

Panthers vs. 49ers FREE Prop Pick

Remi is pouring through tons of datapoints on each line. In fact, anytime the Panthers and 49ers play there’s always several intriguing observations to key in on. Not to mention games played at in Nov almost always follow normal, predictable betting trends.

Carolina vs. San Francisco NFL AI Pick

Remi Robot Icon

Remi, our AI sports genius, has been pouring over mountains of data from every simulation between the Panthers and 49ers and using recursive machine learning and impressive AI to examine the data to a single cover probability.

Interestingly enough, the data has been most watching on the unproportionally assigned emphasis knucklehead sportsbettors regularly put on Carolina’s strength factors between a Panthers team going up against a possibly improved 49ers team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.