Panthers vs. 49ers
FREE NFL AI Predictions
November 24, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Nov 24, 2025
Start Time: 8:15 PM EST​
Venue: ​
49ers Record:
Panthers Record:
OPENING ODDS
CAR Moneyline:
SF Moneyline:
CAR Spread: 0
SF Spread:
Over/Under:
CAR
Betting Trends
SF
Betting Trends
MATCHUP TRENDS
CAR vs. SF
Best Prop Bet
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VS. SPREAD
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+417.7
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VS. SPREAD
1519-1315
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+312.6
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Carolina vs San Francisco AI Prediction:
Free NFL Betting Insights for 11/24/25
Panthers AI Preview

Credit: USA TODAY/IMAGN
49ers AI Preview
Panthers vs. 49ers FREE Prop Pick
Remi is pouring through tons of datapoints on each line. In fact, anytime the Panthers and 49ers play there’s always several intriguing observations to key in on. Not to mention games played at in Nov almost always follow normal, predictable betting trends.
Carolina vs. San Francisco NFL AI Pick

Remi, our AI sports genius, has been pouring over mountains of data from every simulation between the Panthers and 49ers and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Interestingly enough, the data has been most watching on the unproportionally assigned emphasis knucklehead sportsbettors regularly put on Carolina’s strength factors between a Panthers team going up against a possibly improved 49ers team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
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