Lions vs Eagles Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 16)
Updated: 2025-11-09T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Detroit Lions visit the Philadelphia Eagles on November 16, 2025 in a marquee NFC showdown between two playoff‐contending clubs. With the Eagles entering 6-2 at home and the Lions at 6-3 on the road, this game carries major implications for NFC seeding and divisional supremacy.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 16, 2025
Start Time: 9:20 PM EST
Venue: Lincoln Financial Field
Eagles Record: (7-2)
Lions Record: (6-3)
OPENING ODDS
DET Moneyline: +102
PHI Moneyline: -122
DET Spread: +1.5
PHI Spread: -1.5
Over/Under: 48.5
DET
Betting Trends
- Detroit is 7-3 against the spread this season.
PHI
Betting Trends
- Philadelphia is 5-3 against the spread this season.
MATCHUP TRENDS
- Although the Eagles are slight favorites at home, the near‐parity in ATS records suggests the spread may be tighter than many expect. Given Detroit’s strong ATS performance and Philadelphia’s slight slip in consistency, value may exist in backing the Lions to cover or keep this within one possession.
DET vs. PHI
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: S. LaPorta over 49.5 Receiving Yards.
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Detroit vs Philadelphia Prediction & Odds:
Free NFL Betting Insights for 11/16/25
The Lions’ secondary, led by Cam Sutton and rookie Terrion Arnold, will face a major challenge against Philadelphia’s explosive receiving duo of A.J. Brown and DeVonta Smith, who remain among the most dangerous one-two combinations in football. For the Eagles, quarterback Jalen Hurts remains the centerpiece of an offense built on balance, physicality, and versatility. His chemistry with Brown has been electric, while Smith’s route precision and Dallas Goedert’s reliability underneath keep defenses guessing. Philadelphia’s offensive line, though occasionally tested by injuries, remains one of the best in the league, with center Jason Kelce and tackle Lane Johnson continuing to set the standard in protection and run blocking. Expect the Eagles to test Detroit’s defense early with designed quarterback runs and zone reads to slow down the Lions’ pass rush, forcing Hutchinson and company to respect Hurts’ dual-threat ability. The Eagles’ ground game, powered by D’Andre Swift and Kenneth Gainwell, will also be critical in maintaining balance and setting up play-action shots downfield. Defensively, coordinator Vic Fangio’s unit thrives on discipline and disguise, often baiting quarterbacks into checkdowns while collapsing the pocket with interior pressure. Detroit’s offensive efficiency will be tested by Fangio’s ability to adjust mid-game, a hallmark of Philadelphia’s coaching identity. Special teams could also play a decisive role—Detroit’s return game, led by Kalif Raymond, has been consistently productive, while Philadelphia’s kicking and coverage units remain among the most reliable in the league. From a betting perspective, this game is as close as it gets. Detroit’s 7-3 ATS record signals that they’ve been outperforming market expectations, particularly as road underdogs, while Philadelphia’s 5-3 ATS mark indicates they often win but don’t always dominate spreads against top-tier opponents. The contrast in styles—Detroit’s aggressive, fearless approach versus Philadelphia’s measured precision—should create a thrilling chess match that hinges on red-zone execution and turnover margin. The Eagles’ home-field advantage and experience give them a slight edge, but the Lions’ physicality and offensive creativity make them more than capable of pulling off an upset. Expect a high-intensity battle that goes down to the wire, with both teams trading momentum swings in a game that feels more like a playoff preview than a midseason meeting.
Lions have signed DE Ahmed Hassanein to the Practice Squad. pic.twitter.com/ew9eFp4Enn
— Detroit Lions (@Lions) November 10, 2025
Detroit Lions NFL Preview
The Detroit Lions travel to Lincoln Financial Field on November 16, 2025, carrying the swagger of a team that has fully embraced its identity as a legitimate NFC powerhouse. At 7-3, the Lions have cemented themselves as one of the most balanced and disciplined squads in football under head coach Dan Campbell, combining physicality in the trenches with creative offensive design from coordinator Ben Johnson. Quarterback Jared Goff has been the steady hand guiding Detroit’s resurgence, ranking among the league leaders in completion percentage and turnover avoidance. His command of the offense and comfort within Johnson’s play-action-heavy scheme have allowed the Lions to dictate tempo and sustain drives against even the most formidable defenses. Goff’s chemistry with Amon-Ra St. Brown remains the backbone of Detroit’s passing game, as St. Brown’s elite route running and after-the-catch ability consistently move the chains. Meanwhile, Jameson Williams’ growth as a vertical threat has added an explosive dimension to an offense that was already one of the most efficient in football. Tight end Sam LaPorta continues to shine as one of the NFL’s most impactful young players at his position, serving as both a reliable outlet and a mismatch weapon over the middle. The Lions’ rushing attack, powered by the dynamic pairing of Jahmyr Gibbs and David Montgomery, remains the key to their offensive balance. Gibbs’ acceleration and versatility complement Montgomery’s bruising, downhill running style, giving Detroit a backfield capable of punishing defenses in multiple ways. Against a Philadelphia front seven that ranks among the league’s best in run defense, the Lions’ offensive line—anchored by Frank Ragnow, Penei Sewell, and Taylor Decker—will be tested but is more than capable of holding its own. Expect Detroit to use pre-snap motion, quick passes, and inside zone runs to slow down the Eagles’ pass rush and force their linebackers into coverage mismatches.
Defensively, Detroit continues to evolve under Aaron Glenn’s leadership. The Lions have developed a front that thrives on pressure and toughness, led by Aidan Hutchinson, who has blossomed into one of the NFL’s most disruptive edge defenders. Hutchinson’s relentless motor, paired with the interior presence of Alim McNeill, gives Detroit the ability to collapse pockets and limit explosive plays on the ground. Linebackers Derrick Barnes and Jack Campbell bring a blend of speed and physicality that’s been instrumental in shutting down opposing run games, and their performance will be vital in containing Jalen Hurts’ designed runs and scrambles. The secondary, a previous weakness, has stabilized with Cam Sutton providing leadership and rookie Terrion Arnold showcasing poise beyond his years. To succeed in Philadelphia, the Lions must maintain discipline in coverage, as Hurts thrives when extending plays and finding A.J. Brown or DeVonta Smith downfield. Detroit’s tackling efficiency will be critical—missed tackles against Philadelphia’s receivers often turn short gains into back-breaking plays. On special teams, Kalif Raymond has been a spark in the return game, while kicker Michael Badgley’s consistency gives Detroit confidence in close contests. From a betting standpoint, the Lions’ 7-3 ATS record underscores their reliability as road competitors; they’ve consistently outperformed market expectations by staying composed in hostile environments. Their physical style translates well on the road, and Campbell’s motivational edge ensures they rarely enter a game unprepared. To pull off the upset in Philadelphia, Detroit must control the clock, avoid turnovers, and convert red-zone opportunities into touchdowns rather than field goals. If Goff remains poised under pressure and the defense can limit Hurts’ explosive plays, the Lions have the tools to grind out a statement win that would not only strengthen their NFC North lead but also signal that Detroit is ready to challenge for the conference crown.
Credit: USA TODAY/IMAGN
Philadelphia Eagles NFL Preview
The Philadelphia Eagles enter their Week 11 showdown against the Detroit Lions on November 16, 2025, at Lincoln Financial Field with a clear mission—to reassert their dominance as the NFC’s most complete and battle-tested team. At 6-2, the Eagles remain firmly in control of their playoff destiny, and this matchup against the surging Lions offers both a statement opportunity and a potential postseason preview. Under head coach Nick Sirianni, Philadelphia has maintained its reputation for consistency and composure, blending elite physicality in the trenches with an offense that thrives on versatility and balance. Quarterback Jalen Hurts continues to serve as the emotional and tactical centerpiece of this team. His ability to blend power running with surgical passing has made him one of the league’s most dangerous dual-threat quarterbacks. Even when defenses load the box to contain him, Hurts finds ways to extend plays, attack open zones, and deliver timely strikes to his array of playmakers. His chemistry with wide receiver A.J. Brown has reached an elite level, as Brown’s combination of physicality, contested-catch prowess, and run-after-catch explosiveness has consistently tilted matchups in Philadelphia’s favor. DeVonta Smith, meanwhile, brings the finesse and route precision that perfectly complements Brown’s dominance, creating a receiving tandem that can stretch the field horizontally and vertically. Tight end Dallas Goedert remains a reliable safety valve, excelling on third downs and in the red zone where Hurts often leans on his trust and timing with the veteran pass-catcher. The Eagles’ ground game, featuring D’Andre Swift and Kenneth Gainwell, adds another dimension, giving the offense flexibility to adapt to defensive schemes while wearing down opponents over four quarters. Philadelphia’s offensive line, led by veterans Jason Kelce and Lane Johnson, remains among the league’s elite, setting the tone with toughness and discipline.
However, against a fierce Detroit front led by Aidan Hutchinson, protection will be critical—particularly in containing edge pressure and creating clean pockets for Hurts to operate. On defense, coordinator Vic Fangio’s scheme has continued to evolve into one of the NFL’s most intricate and adaptive units. The Eagles have emphasized generating pressure without sacrificing coverage integrity, with Jalen Carter and Jordan Davis anchoring a defensive line that overwhelms opponents at the point of attack. On the edges, Haason Reddick and Josh Sweat remain relentless disruptors capable of dictating protection schemes, and their ability to collapse the pocket could be the deciding factor against Jared Goff’s timing-based passing game. The secondary, featuring Darius Slay and James Bradberry, has regained rhythm after an uneven start to the season, providing the versatility needed to match up against Detroit’s mix of physical receivers and speed threats. The Eagles’ linebacking corps, though not the team’s strongest unit, has improved in communication and pursuit angles, reducing the explosive plays that plagued them early in the year. Special teams, long a quiet strength for Philadelphia, could also play a pivotal role in this contest, with kicker Jake Elliott continuing to deliver in high-pressure moments and Britain Covey’s return skills capable of flipping field position. From a betting perspective, Philadelphia’s 5-3 ATS record mirrors their on-field reality: a team that usually wins but doesn’t always dominate the spread due to their deliberate style and tendency to play close, physical games. Still, at home, the Eagles have been remarkably resilient, riding both crowd energy and situational awareness to control games in the second half. To secure victory against a dangerous Lions team, Philadelphia must play to its strengths—control the line of scrimmage, win early downs, and force Goff into uncomfortable situations where the pass rush can take over. Hurts’ composure, coupled with the team’s late-game execution, has often been the difference in tight contests, and that formula will once again be crucial. If the Eagles maintain their discipline, capitalize on Detroit’s mistakes, and leverage their veteran experience, they should have enough firepower and toughness to emerge from this heavyweight NFC clash with another statement win in front of their home crowd.
Go Birds Go@BetMGM | #FlyEaglesFly pic.twitter.com/IEEB38SfrD
— Philadelphia Eagles (@Eagles) November 11, 2025
Detroit vs. Philadelphia Prop Picks (AI)
Detroit vs. Philadelphia Prediction (AI)
Remi, our AI sports genius, has been pouring over millions of data from every past game between the Lions and Eagles and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.
Remi has been most focused on the linear correlation of factor emotional bettors regularly put on coaching factors between a Lions team going up against a possibly deflated Eagles team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
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Below is our current AI Detroit vs Philadelphia picks, computer picks Lions vs Eagles, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Lions Betting Trends
Detroit is 7-3 against the spread this season.
Eagles Betting Trends
Philadelphia is 5-3 against the spread this season.
Lions vs. Eagles Matchup Trends
Although the Eagles are slight favorites at home, the near‐parity in ATS records suggests the spread may be tighter than many expect. Given Detroit’s strong ATS performance and Philadelphia’s slight slip in consistency, value may exist in backing the Lions to cover or keep this within one possession.
Detroit vs. Philadelphia Game Info
What time does Detroit vs Philadelphia start on November 16, 2025?
Detroit vs Philadelphia starts on November 16, 2025 at 9:20 PM EST.
Where is Detroit vs Philadelphia being played?
Venue: Lincoln Financial Field.
What are the opening odds for Detroit vs Philadelphia?
Spread: Philadelphia -1.5
Moneyline: Detroit +102, Philadelphia -122
Over/Under: 48.5
What are the records for Detroit vs Philadelphia?
Detroit: (6-3) | Philadelphia: (7-2)
What is the AI best bet for Detroit vs Philadelphia?
Remi's searched hard and found the best prop for this matchup: S. LaPorta over 49.5 Receiving Yards.. Prices move—always shop for the best number.
What are Detroit vs Philadelphia trending bets?
Although the Eagles are slight favorites at home, the near‐parity in ATS records suggests the spread may be tighter than many expect. Given Detroit’s strong ATS performance and Philadelphia’s slight slip in consistency, value may exist in backing the Lions to cover or keep this within one possession.
What are Detroit trending bets?
DET trend: Detroit is 7-3 against the spread this season.
What are Philadelphia trending bets?
PHI trend: Philadelphia is 5-3 against the spread this season.
Where can I find AI Picks for Detroit vs Philadelphia?
See our latest NFL picks and odds pages for 2025 to compare prices before you bet.
Detroit vs. Philadelphia Odds
AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Detroit vs Philadelphia trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.
Detroit vs Philadelphia Opening Odds
DET Moneyline:
+102 PHI Moneyline: -122
DET Spread: +1.5
PHI Spread: -1.5
Over/Under: 48.5
Detroit vs Philadelphia Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
|
–
–
|
+550
-800
|
+13 (-110)
-13 (-110)
|
O 43 (-110)
U 43 (-110)
|
|
|
Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
|
–
–
|
+130
-155
|
+2.5 (-102)
-2.5 (-118)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
|
–
–
|
+165
-200
|
+3.5 (-110)
-3.5 (-110)
|
O 42.5 (-110)
U 42.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
|
–
–
|
+140
-165
|
+3 (-110)
-3 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
|
–
–
|
-150
+125
|
-3 (-105)
+3 (-115)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
|
–
–
|
-350
+280
|
-7 (-110)
+7 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
|
–
–
|
+195
-235
|
+5.5 (-110)
-5.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
|
–
–
|
+200
-250
|
+5.5 (-110)
-5.5 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
|
–
–
|
-325
+260
|
-6.5 (-118)
+6.5 (-102)
|
O 37.5 (-110)
U 37.5 (-110)
|
|
|
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
|
–
–
|
-150
+125
|
-2.5 (-118)
+2.5 (-102)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
|
–
–
|
+140
-165
|
+3 (-110)
-3 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
|
–
–
|
-200
+165
|
-4 (-105)
+4 (-115)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
|
–
–
|
-400
+300
|
-7.5 (-110)
+7.5 (-110)
|
O 39.5 (-110)
U 39.5 (-110)
|
|
|
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
|
–
–
|
+120
-145
|
+2.5 (-105)
-2.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
|
–
–
|
-175
+145
|
-3.5 (-102)
+3.5 (-118)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Nov 20, 2025 8:15PM EST
Buffalo Bills
Houston Texans
11/20/25 8:15PM
Bills
Texans
|
–
–
|
-154
+130
|
-2.5 (-128)
+2.5 (+104)
|
O 45.5 (-104)
U 45.5 (-118)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Detroit Lions vs. Philadelphia Eagles on November 16, 2025 at Lincoln Financial Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| PHI@GB | PHI +1.5 | 54.8% | 4 | WIN |
| PHI@GB | UNDER 45.5 | 52.4% | 2 | WIN |
| PHI@GB | SAQUON BARKLEY OVER 17.5 RUSH ATT | 56.6% | 6 | WIN |
| PHI@GB | JOSH JACOBS UNDER 42.5 1ST HALF RUSH + REC YDS | 54.4% | 4 | LOSS |
| NO@CAR | CAR -5 | 55.4% | 5 | LOSS |
| BAL@MIN | BAL -3.5 | 57.6% | 7 | WIN |
| CLE@NYJ | CLE -130 | 65.4% | 7 | LOSS |
| NYG@CHI | CHI -4.5 | 55.2% | 5 | LOSS |
| NE@TB | TB -2 | 56.1% | 6 | LOSS |
| LAR@SF | LAR -5.5 | 53.3% | 2 | WIN |
| JAC@HOU | UNDER 38 | 54.8% | 5 | LOSS |
| ARI@SEA | TREY MCBRIDE OVER 9 RECV TARGETS | 55.8% | 5 | WIN |
| DET@WAS | TERRION ARNOLD OVER 4.5 TACKLES + ASSTS | 56.8% | 6 | LOSS |
| JAC@HOU | TRAVIS ETIENNE UNDER 74.5 RUSH + REC YDS | 54.4 | 4 | LOSS |
| LV@DEN | DANIEL CARLSON OVER 1.5 FIELD GOALS | 55.2% | 5 | LOSS |
| LV@DEN | COURTLAND SUTTON OVER 53.5 RECV YDS | 54.2% | 4 | LOSS |
| LV@DEN | RILEY MOSS OVER 4.5 TACKLE + ASST | 54.8% | 4 | WIN |
| LV@DEN | UNDER 43 | 53.4% | 2 | WIN |
| ARI@DAL | BUDDA BAKER OVER 7.5 TACKLES + ASSTS | 54.4% | 4 | WIN |
| ARI@DAL | GEORGE PICKENS OVER 4.5 RECEPTIONS | 56.6% | 6 | WIN |
| DEN@HOU | WIL LUTZ OVER 1.5 MADE FIELD GOALS | 54.2% | 3 | LOSS |
| SEA@WAS | SEA -3 | 56.7% | 6 | WIN |
| IND@PIT | IND -3 | 56.8% | 6 | LOSS |
| LAC@TEN | LAC -9.5 | 56.2% | 6 | LOSS |
| CHI@CIN | CHI -2.5 | 52.6% | 2 | WIN |
| SEA@WAS | OVER 48 | 52.9% | 2 | WIN |
| SEA@WAS | JAYDEN DANIELS OVER 20.5 PASS COMP | 56.7% | 6 | LOSS |
| JAC@LV | JAC -140 | 64.2% | 7 | WIN |
| NO@LAR | LAR -14 | 55.0% | 4 | WIN |
| DEN@HOU | HOU -1.5 | 54.2% | 3 | LOSS |
| CAR@GB | GB -12.5 | 55.4% | 5 | LOSS |
| SF@NYG | NYG +2.5 | 56.1% | 5 | LOSS |
| BAL@MIA | TUA TAGOVAILOA UNDER 0.5 INT | 55.3% | 5 | LOSS |
| TB@NO | TB -3.5 | 52.3% | 1 | WIN |
| GB@PIT | GB -2.5 | 52.3% | 1 | WIN |
| SF@HOU | SF +2.5 | 56.0% | 6 | LOSS |
| NYG@PHI | NYG +7.5 | 53.9% | 3 | LOSS |
| BUF@CAR | CAR +7.5 | 54.2% | 3 | LOSS |
| DAL@DEN | DAL +3.5 | 55.0% | 4 | LOSS |
| MIA@ATL | MIA +7 | 54.3% | 4 | WIN |
| CLE@NE | CLE +7 | 56.8% | 6 | LOSS |
| TB@NO | BAKER MAYFIELD OVER 15.5 RUSH YDS | 56.6% | 6 | LOSS |
| MIN@LAC | JUSTIN HERBERT PASS ATT UNDER 35.5 | 55.5% | 5 | WIN |
| TB@DET | TB +6.5 | 54.4% | 4 | LOSS |
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |