Giants vs Broncos Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 19)

Updated: 2025-10-12T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Giants head west to take on the Denver Broncos on October 19, 2025, in a clash between a Giants team showing flashes of resurgence and a Broncos squad aiming to lean on its defense and home-field edge. Denver enters as the favorite, banking on its stout defensive presence and growing identity, while New York looks to its young weapons and a stronger rushing attack to keep pace.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 19, 2025

Start Time: 4:05 PM EST​

Venue: Empower Field at Mile High​

Broncos Record: (3-2)

Giants Record: (2-4)

OPENING ODDS

NYG Moneyline: +290

DEN Moneyline: -366

NYG Spread: +7

DEN Spread: -7.0

Over/Under: 40.5

NYG
Betting Trends

  • New York holds a 2–3 record against the spread this season.

DEN
Betting Trends

  • Denver sits at a 2–2–1 record ATS in 2025.

MATCHUP TRENDS

  • Opening odds list the Giants as 7-point underdogs in Denver, reflecting both Denver’s home advantage and confidence in its defense.

NYG vs. DEN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: B. Nix over 16.5 Rushing Yards.

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New York vs Denver Prediction & Odds:
Free NFL Betting Insights for 10/19/25

The Week 7 matchup between the New York Giants and the Denver Broncos on October 19, 2025, at Empower Field at Mile High sets up as a test of physicality, execution, and mental toughness for two teams trending in opposite directions. The Broncos enter the game relying on their elite defense and home-field advantage at altitude, while the Giants are trying to build on the momentum of a rejuvenated rushing attack and improved offensive rhythm. Denver’s defense, led by standout pass rusher Nik Bonitto and interior anchor Zach Allen, has been nothing short of dominant in recent weeks. Their 13–11 win over the Jets showcased their ability to take over games through relentless pressure and gap discipline — holding New York to negative passing yards and nine sacks. However, the Broncos’ offensive line depth is a growing concern after losing starting left guard Ben Powers to a season-ending bicep injury, which could force rookie quarterback Bo Nix to face added pressure against an improving Giants front seven. Denver’s offense has leaned heavily on efficiency and quick reads from Nix, supported by a running back committee led by Javonte Williams and Jaleel McLaughlin, but their inability to sustain drives and finish in the red zone has left points on the table. On the other side, the Giants’ resurgence has centered around rookie running back Cam Skattebo, who exploded for 172 rushing yards and three touchdowns against Philadelphia last week. His punishing running style and ability to extend plays after contact have injected new life into a Giants offense that had struggled for consistency.

Quarterback Jaxson Dart has shown flashes of confidence and accuracy but remains inconsistent, especially when facing heavy pressure. Against a Broncos defense that thrives on disguising blitzes and collapsing pockets, Dart’s poise and quick decision-making will be crucial. The Giants’ offensive line has improved in run blocking but remains vulnerable in pass protection, which could be problematic against Denver’s edge rush. Defensively, New York will focus on containing Bo Nix, forcing him into third-and-long situations, and capitalizing on Denver’s protection issues. Kayvon Thibodeaux and Dexter Lawrence will play key roles in pressuring Nix, while the secondary, led by Deonte Banks and Xavier McKinney, must prevent deep shots to Courtland Sutton and Marvin Mims Jr. The chess match will come down to which team executes better on early downs — the Giants need to stay ahead of the sticks with their ground game, while the Broncos must protect Nix long enough to generate rhythm. Expect a grind-it-out contest dominated by defense, field position, and red-zone efficiency, where turnovers and special teams could decide the outcome. Denver’s home altitude advantage and defensive consistency make them the slight favorite, but if the Giants’ run game can control tempo and limit mistakes, this could turn into a gritty, low-scoring battle that comes down to the final possession.

New York Giants NFL Preview

The New York Giants travel to Denver in Week 7 aiming to build upon the renewed sense of confidence that has emerged from their recent offensive resurgence, particularly in the running game. Rookie running back Cam Skattebo has quickly become the heartbeat of this Giants offense, bringing a blend of toughness, balance, and relentless drive that has redefined how New York controls games. His breakout performance against Philadelphia — 172 yards and three touchdowns — showcased not only his individual talent but also the team’s commitment to physicality and clock control. Head coach Brian Daboll has clearly shifted his offensive philosophy to emphasize ground dominance and efficient play-calling, taking pressure off quarterback Jaxson Dart. The rookie signal-caller has shown flashes of potential, using his mobility and arm strength to extend plays, but his decision-making and consistency under duress remain developing areas. Against Denver’s defense, which has been ferocious in collapsing pockets and creating turnovers, Dart must play within structure, relying on timing throws and high-percentage passes to neutralize the Broncos’ pressure. Expect the Giants to use a heavy dose of pre-snap motion, zone reads, and short passes to the flat to test Denver’s linebackers and slow down their edge rush.

The offensive line, led by Andrew Thomas and John Michael Schmitz, will need to play its best game of the season to keep Nik Bonitto and Zach Allen from dictating the flow. Defensively, the Giants have quietly improved, showing better discipline in gap assignments and secondary communication. Dexter Lawrence continues to be the anchor up front, commanding double teams and freeing up Kayvon Thibodeaux to attack from the edge. Their defensive approach will focus on forcing Bo Nix into long third downs, where Wink Martindale can dial up exotic blitz packages and test the rookie’s composure. The secondary, featuring Deonte Banks and Xavier McKinney, will be tasked with containing Courtland Sutton and preventing Denver’s quick-pass rhythm from finding a groove. Field position and red-zone execution will be pivotal — if New York can capitalize on drives with touchdowns rather than field goals, they’ll have a legitimate shot at the upset. Special teams also loom large; Graham Gano’s reliability from distance and the return game’s potential spark could be difference-makers in a tight, low-scoring affair. The altitude in Denver will test the Giants’ conditioning, making early game pacing and rotation management critical. To win, the Giants must stick to their blueprint: dominate time of possession, stay disciplined defensively, and avoid giving Denver short fields. If Skattebo continues to control the ground game and Dart limits turnovers, the Giants have the tools to grind out a road win against a Broncos team built on defense but still searching for offensive rhythm.

The New York Giants head west to take on the Denver Broncos on October 19, 2025, in a clash between a Giants team showing flashes of resurgence and a Broncos squad aiming to lean on its defense and home-field edge. Denver enters as the favorite, banking on its stout defensive presence and growing identity, while New York looks to its young weapons and a stronger rushing attack to keep pace. New York vs Denver AI Prediction: Free NFL Betting Insights for Oct 19. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Denver Broncos NFL Preview

The Denver Broncos return home to Empower Field at Mile High for their Week 7 matchup against the New York Giants looking to continue their defensive dominance and establish more consistency on offense. Denver’s defense has been the driving force behind its recent success, spearheaded by a front seven that has overwhelmed opponents through relentless pressure and disciplined containment. In their 13–11 victory over the Jets, the Broncos’ defense delivered a statement performance — recording nine sacks, holding the opposition to negative passing yards, and allowing just 80 total yards. That kind of performance reflects defensive coordinator Vance Joseph’s growing confidence in using creative blitz schemes and heavy rotations, keeping opposing quarterbacks under constant stress. Nik Bonitto has been a breakout star on the edge, combining speed and power to collapse pockets, while Zach Allen and D.J. Jones have solidified the interior. Against a Giants offense that leans heavily on the running game behind rookie standout Cam Skattebo, Denver will prioritize setting the edge, maintaining gap discipline, and forcing quarterback Jaxson Dart into obvious passing situations where mistakes can be exploited. Linebackers Alex Singleton and Josey Jewell will play key roles in shadowing Skattebo out of the backfield and plugging inside runs before they reach the second level. Offensively, the Broncos are still finding their rhythm under rookie quarterback Bo Nix, who has shown flashes of composure and quick decision-making but continues to navigate growing pains behind a reshuffled offensive line.

The loss of starting left guard Ben Powers to a bicep injury is a significant blow, forcing Denver to adjust with more max-protect looks and quicker releases in passing situations. Running backs Javonte Williams and Jaleel McLaughlin will need to shoulder more of the workload to alleviate pressure on Nix and keep the Giants’ pass rush honest. Expect the Broncos to use screen passes, bootlegs, and play-action to take advantage of an aggressive Giants defense that thrives on pressure. The receiving corps — led by Courtland Sutton and rookie Marvin Mims Jr. — must find separation against a New York secondary anchored by Deonte Banks and Xavier McKinney. Sustaining drives and improving red-zone efficiency remain Denver’s biggest offensive priorities; too often this season, promising drives have stalled due to penalties or breakdowns in protection. At home, Denver’s altitude and crowd noise serve as natural advantages, often wearing down opponents not used to the conditions, especially late in games. Special teams could also play a decisive role — kicker Wil Lutz has been steady from distance, and field position battles could swing momentum in what figures to be a low-scoring, defensive game. For the Broncos, the formula for victory is clear: dominate the trenches, control the pace, and capitalize on turnovers created by their defense. If Bo Nix manages the game effectively and the defense continues its elite form, Denver is well-positioned to protect its home turf and maintain its push toward playoff contention.

New York vs. Denver Prop Picks (AI)

Remi is pouring through mountains of stats on each line. In fact, anytime the Giants and Broncos play there’s always several intriguing observations to key in on. Not to mention games played at Empower Field at Mile High in Oct almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: B. Nix over 16.5 Rushing Yards.

New York vs. Denver Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every angle between the Giants and Broncos and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

Remi has been most watching on the linear correlation of factor human bettors tend to put on New York’s strength factors between a Giants team going up against a possibly deflated Broncos team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI New York vs Denver picks, computer picks Giants vs Broncos, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Giants Betting Trends

New York holds a 2–3 record against the spread this season.

Broncos Betting Trends

Denver sits at a 2–2–1 record ATS in 2025.

Giants vs. Broncos Matchup Trends

Opening odds list the Giants as 7-point underdogs in Denver, reflecting both Denver’s home advantage and confidence in its defense.

New York vs. Denver Game Info

New York vs Denver starts on October 19, 2025 at 4:05 PM EST.

Venue: Empower Field at Mile High.

Spread: Denver -7.0
Moneyline: New York +290, Denver -366
Over/Under: 40.5

New York: (2-4)  |  Denver: (3-2)

Remi's searched hard and found the best prop for this matchup: B. Nix over 16.5 Rushing Yards.. Prices move—always shop for the best number.

Opening odds list the Giants as 7-point underdogs in Denver, reflecting both Denver’s home advantage and confidence in its defense.

NYG trend: New York holds a 2–3 record against the spread this season.

DEN trend: Denver sits at a 2–2–1 record ATS in 2025.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

New York vs. Denver Odds

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the New York vs Denver trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

New York vs Denver Opening Odds

NYG Moneyline: +290
DEN Moneyline: -366
NYG Spread: +7
DEN Spread: -7.0
Over/Under: 40.5

New York vs Denver Live Odds

Games PTS ML SPR O/U
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
+159
-185
+3.5 (-115)
-3.5 (-105)
O 45 (-110)
U 45 (-110)
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
+290
-360
+7 (-110)
-7 (-110)
O 40.5 (-110)
U 40.5 (-110)
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
-400
+320
-7.5 (-105)
+7.5 (-115)
O 45.5 (-110)
U 45.5 (-110)
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
+235
-280
+6.5 (-110)
-6.5 (-110)
O 44.5 (-105)
U 44.5 (-115)
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
+253
-305
+7 (-120)
-7 (+100)
O 50.5 (-110)
U 50.5 (-110)
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
+317
-395
+7 (-105)
-7 (-115)
O 44 (-110)
U 44 (-110)
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
+105
-125
+1 (-105)
-1 (-115)
O 41.5 (-110)
U 41.5 (-110)
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
+280
-350
+7 (-110)
-7 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
-215
+183
-4 (-110)
+4 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
+146
-170
+3.5 (-120)
-3.5 (+100)
O 50.5 (-110)
U 50.5 (-110)
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
+750
-1200
+14 (-115)
-14 (-105)
O 47 (-110)
U 47 (-110)
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
-175
+150
-3 (-120)
+3 (+100)
O 45 (-110)
U 45 (-110)
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
+465
-630
+10.5 (-115)
-10.5 (-105)
O 48 (-105)
U 48 (-115)
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
-430
+340
-8 (-110)
+8 (-110)
O 50.5 (-110)
U 50.5 (-110)
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
-120
+102
pk
pk
O 49.5 (-110)
U 49.5 (-110)
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
-136
+116
-2.5 (-110)
+2.5 (-110)
O 48.5 (-110)
U 48.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Giants vs. Denver Broncos on October 19, 2025 at Empower Field at Mile High.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS