Colts vs. Rams
FREE NFL AI Predictions
September 28, 2025



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AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 28, 2025

Start Time: 4:05 PM EST​

Venue: ​

Rams Record:

Colts Record:

OPENING ODDS

IND Moneyline:

LAR Moneyline:

IND Spread: 0

LAR Spread:

Over/Under:

IND
Betting Trends

LAR
Betting Trends

MATCHUP TRENDS

IND vs. LAR
Best Prop Bet

LIVE NFL ODDS

NFL ODDS COMPARISON

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VAULT
VS. SPREAD
300-211
VAULT
NET UNITS
(INCL VIG)
+437.5
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$43,753
EXECUTIVE
VS. SPREAD
1527-1319
EXECUTIVE
NET UNITS
(INCL VIG)
+326.8
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$32,679

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Indianapolis vs Los Angeles AI Prediction:
Free NFL Betting Insights for 9/28/25

Colts AI Preview

 Indianapolis vs Los Angeles AI Prediction: Free NFL Betting Insights for Sep 28. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Rams AI Preview

Colts vs. Rams FREE Prop Pick

Remi is pouring through tons of datapoints on each line. In fact, anytime the Colts and Rams play there’s always several intriguing angles to key in on. Not to mention games played at in Sep can often follow normal, predictable betting trends.

Indianapolis vs. Los Angeles NFL AI Pick

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over millions of data from every past game between the Colts and Rams and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Remi has been most keyed in on the linear correlation of factor knucklehead sportsbettors often put on coaching factors between a Colts team going up against a possibly deflated Rams team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

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