The September 28, 2025 matchup between the Green Bay Packers and Dallas Cowboys at AT&T Stadium arrives with layers of intrigue beyond the standings, as the Packers enter riding the momentum of a blockbuster trade for Micah Parsons while the Cowboys scramble to adapt after losing both their defensive anchor and their top offensive playmaker in CeeDee Lamb. Green Bay has started the season competitively but comes into this one with offensive line concerns, as right tackle Zach Tom is sidelined, forcing Jordan Love and the Packers’ coaching staff to adjust protections against a Dallas front still capable of generating pressure through scheme even without Parsons. That said, Dallas’s pass defense has been exposed in recent weeks, giving up over 500 passing yards in a single outing, which opens the door for Green Bay to attack aggressively through the air with intermediate routes and timely vertical shots if their line can buy Love the time he needs. The Cowboys, meanwhile, face serious challenges in retooling their offense without Lamb, leaving Dak Prescott (or their starter under center if injuries complicate things further) to rely more heavily on tight ends and depth receivers to keep drives alive while leaning on the run game to shorten contests and protect a banged-up offensive line already missing Tyler Booker and Cooper Beebe.

On defense, Dallas must disguise pressures, blitz selectively, and play disciplined coverage to keep the Packers from dictating tempo, while Green Bay will count on Parsons’ immediate impact as a pass-rushing force to collapse pockets and help tilt the game in their favor. Special teams and hidden yardage will matter, as both clubs have shown vulnerabilities sustaining drives and will need short fields to maximize efficiency in the red zone. From a betting perspective, the line has shifted toward Green Bay, with the market heavily backing the Packers due to Dallas’s injury issues and the emotional jolt of Parsons suiting up against his former team, though Dallas’s home-field edge and capacity to grind out games prevent this from being a runaway pick. The game will likely come down to whether Green Bay can protect Love long enough to exploit Dallas’s weakened secondary and whether the Cowboys can manufacture enough offense without Lamb to keep pace. If the Packers establish rhythm early and Parsons wreaks havoc, they have every chance to notch a statement road win, but if Dallas steadies itself, leans on the ground game, and uses the AT&T crowd to fuel defensive energy, they could grind out a hard-fought result and remind the NFC they remain dangerous even amid adversity.