Jaguars vs Colts Prediction — AI Finds CAN'T MISS NFL Lines & Props (Jan 05)
Updated: 2024-12-29T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Jacksonville Jaguars (4-12) are set to face the Indianapolis Colts (7-9) on January 5, 2025, at Lucas Oil Stadium in Indianapolis. The Colts are favored by 5.5 points, with the over/under set at 44.5 points.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jan 05, 2025
Start Time: 2:00 PM EST
Venue: Lucas Oil Stadium
Colts Record: (7-9)
Jaguars Record: (4-12)
OPENING ODDS
JAC Moneyline: +183
IND Moneyline: -222
JAC Spread: +5
IND Spread: -5.0
Over/Under: 43.5
JAC
Betting Trends
- The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.
IND
Betting Trends
- The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.
MATCHUP TRENDS
- Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.
JAC vs. IND
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Jacksonville vs Indianapolis Prediction & Odds:
Free NFL Betting Insights for 1/5/25
Head coach Doug Pederson has emphasized the importance of finishing strong, noting that a victory would result in a 4-2 record within the AFC South, a silver lining in an otherwise challenging year. Jacksonville’s offense has faced difficulties, particularly in sustaining drives. They rank second-worst in the league in offensive plays per game, averaging 58. The passing game has been middling, with 32.1 attempts per game, ranking 17th in the NFL, while the rushing attack averages 23.8 attempts per game, placing them near the bottom of the league. Defensively, the Jaguars have had notable struggles, especially against the pass. They possess the league’s worst pass defense, allowing the most EPA (Expected Points Added) per dropback to opposing quarterbacks and ranking 25th in defensive Pass Success Rate. This vulnerability could be a focal point for the Colts’ game plan. As the game approaches, both teams will look to exploit each other’s weaknesses. The Colts may focus on their passing attack to take advantage of Jacksonville’s porous secondary, while the Jaguars will aim to establish a balanced offense to challenge Indianapolis’s defense. In this AFC South matchup, the Colts are favored by 5.5 points, with the total points over/under set at 44.5. Given the teams’ recent performances and statistical profiles, this game presents an intriguing contest for both fans and bettors, with the potential for unexpected developments as both teams seek to end their seasons on a high note.
The Finale#JAXvsIND pic.twitter.com/hJsHevmV7Y
— Jacksonville Jaguars (@Jaguars) January 2, 2025
Jacksonville Jaguars NFL Preview
The Jacksonville Jaguars enter their final game of the season with a 4-12 record, looking to end a challenging year on a high note. Despite their struggles, the Jaguars see this matchup against the Colts as an opportunity to gain valuable experience for their young roster and evaluate areas for improvement heading into the offseason. Rookie quarterback Caleb Williams has been a bright spot for Jacksonville, showcasing his potential as a future franchise cornerstone. Williams, the first overall pick in the 2024 NFL Draft, has displayed flashes of brilliance, throwing for over 3,300 yards and 19 touchdowns. His mobility and ability to extend plays have added a dynamic element to the Jaguars’ offense, though inconsistencies and turnovers have limited the unit’s effectiveness. Improving protection for Williams will be a top priority, as the offensive line has struggled to keep him upright against aggressive pass rushes. The Jaguars’ rushing attack, led by Travis Etienne Jr., has been inconsistent, with flashes of success overshadowed by games where the ground game failed to establish itself. Etienne has surpassed 900 rushing yards on the season but has been unable to consistently break through opposing defenses due to a lack of support from the offensive line. Establishing the run early against Indianapolis will be crucial to relieving pressure on Williams and opening up opportunities in the passing game. Defensively, the Jaguars have faced significant challenges, particularly in defending the pass. Jacksonville ranks among the league’s worst in pass defense, allowing a high number of explosive plays through the air. The front seven, led by Josh Allen, has been effective in generating pressure at times, but the lack of consistency in the secondary has hampered the overall defensive effort. Against a veteran quarterback like Joe Flacco, the Jaguars will need to tighten their coverage and create turnovers to keep the game competitive. Special teams have been a mixed bag for Jacksonville. Kicker Brandon McManus has been dependable, converting key field goals when given the opportunity. However, the return game has lacked impact, failing to provide the offense with favorable field position in critical moments. Coverage units will need to be sharp to prevent Indianapolis from gaining an edge in field position. Head coach Doug Pederson has emphasized the importance of finishing the season with a strong performance, highlighting the growth and development of the team’s young players. For the Jaguars, this game represents an opportunity to evaluate their roster, identify areas for improvement, and build confidence heading into the offseason. Keys to victory for Jacksonville include protecting Caleb Williams, establishing a balanced offensive attack, and improving defensive execution to limit the Colts’ productive offense. Special teams will also play a key role in maintaining field position and converting scoring opportunities. While the Jaguars are underdogs, they have the potential to surprise the Colts if they execute effectively and capitalize on mistakes. A win in this divisional matchup would not only boost morale but also provide a positive note to conclude a rebuilding season. Jacksonville’s young core will look to use this game as a stepping stone toward greater success in the future.

Credit: USA TODAY/IMAGN
Indianapolis Colts NFL Preview
The Indianapolis Colts, standing at 7-9, are set to host the Jacksonville Jaguars in their season finale at Lucas Oil Stadium. Aiming to conclude the season with a .500 record, the Colts have shown resilience and growth, particularly in the latter part of the season. Offensively, the Colts have found a rhythm under quarterback Joe Flacco. In Week 17, the offense was prolific, scoring 33 points against the New York Giants, a performance that exceeded the Giants’ defensive season average. Flacco’s command of the offense was evident, as he achieved a top 10 Pass Success Rate for the week, demonstrating his ability to effectively distribute the ball to his playmakers. The ground game has been anchored by running back Jonathan Taylor, who has surpassed 1,100 rushing yards this season. The Colts’ commitment to the run is reflected in their 28.9 carries per game, ranking seventh in the NFL. This balanced offensive approach has been instrumental in controlling the tempo of games and sustaining drives. The offensive line has played a pivotal role in the team’s success, providing strong protection for Flacco and creating running lanes for Taylor. Despite facing some injuries throughout the season, the line’s depth and cohesion have enabled the Colts to maintain their offensive productivity. This unit will be crucial in neutralizing Jacksonville’s defensive front and giving Flacco the time needed to exploit the Jaguars’ weaknesses in coverage. Defensively, the Colts have been a mixed bag, showing the ability to step up in critical moments but also allowing some big plays. Their front seven, led by DeForest Buckner and Shaquille Leonard, has been effective in stopping the run and applying pressure on opposing quarterbacks. The secondary, while capable of creating turnovers, has been inconsistent in coverage, allowing teams to capitalize on breakdowns. Against a Jaguars team with a rookie quarterback, the Colts will look to generate pressure and force Caleb Williams into hurried decisions. Special teams have been a consistent strength for Indianapolis. Kicker Matt Gay has been reliable throughout the season, converting crucial field goals in tight games. The punt and kickoff coverage units have also performed well, helping to tilt the field position battle in the Colts’ favor. Head coach Shane Steichen has emphasized the importance of finishing the season strong, not only for team morale but also to build momentum heading into the offseason. Steichen’s offensive acumen has been evident in the Colts’ improvement in recent weeks, and his ability to adapt the game plan to exploit opponents’ weaknesses has been a key factor in their success. Keys to victory for the Colts include maintaining a balanced offensive approach, using the run game to set up play-action opportunities, and protecting Flacco from Jacksonville’s pass rush. Defensively, they will aim to disrupt Williams’ rhythm, limit big plays, and capitalize on any mistakes by the rookie quarterback. Winning the turnover battle will be critical in what is expected to be a competitive divisional matchup. As the Colts take the field at Lucas Oil Stadium, the home crowd will provide an energetic backdrop for their season finale. A victory over the Jaguars would not only improve their record to 8-9 but also serve as a positive note to conclude a season of growth and development. With a strong foundation in place, the Colts are poised to use this game as a stepping stone toward a more competitive campaign in 2025.
Thursday's practice report for #JAXvsIND: pic.twitter.com/3YT1LG0foR
— Indianapolis Colts (@Colts) January 2, 2025
Jacksonville vs. Indianapolis Prop Picks (AI)
Jacksonville vs. Indianapolis Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every past game between the Jaguars and Colts and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.
Remi has been most keyed in on the unproportionally assigned emphasis knucklehead sportsbettors regularly put on Indianapolis’s strength factors between a Jaguars team going up against a possibly improved Colts team. We’ve found the true game analytics might reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Jacksonville vs Indianapolis picks, computer picks Jaguars vs Colts, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Jaguars Betting Trends
The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.
Colts Betting Trends
The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.
Jaguars vs. Colts Matchup Trends
Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.
Jacksonville vs. Indianapolis Game Info
What time does Jacksonville vs Indianapolis start on January 05, 2025?
Jacksonville vs Indianapolis starts on January 05, 2025 at 2:00 PM EST.
Where is Jacksonville vs Indianapolis being played?
Venue: Lucas Oil Stadium.
What are the opening odds for Jacksonville vs Indianapolis?
Spread: Indianapolis -5.0
Moneyline: Jacksonville +183, Indianapolis -222
Over/Under: 43.5
What are the records for Jacksonville vs Indianapolis?
Jacksonville: (4-12) | Indianapolis: (7-9)
What is the AI best bet for Jacksonville vs Indianapolis?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Jacksonville vs Indianapolis trending bets?
Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.
What are Jacksonville trending bets?
JAC trend: The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.
What are Indianapolis trending bets?
IND trend: The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.
Where can I find AI Picks for Jacksonville vs Indianapolis?
See our latest NFL picks and odds pages for 2025 to compare prices before you bet.
Jacksonville vs. Indianapolis Odds
Remi is pouring through mountains of stats on each player. In fact, anytime the Jacksonville vs Indianapolis trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable betting trends.
Jacksonville vs Indianapolis Opening Odds
JAC Moneyline:
+183 IND Moneyline: -222
JAC Spread: +5
IND Spread: -5.0
Over/Under: 43.5
Jacksonville vs Indianapolis Live Odds
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Minnesota Vikings
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–
–
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+148
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+3 (+100)
-3 (-120)
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O 44.5 (-110)
U 44.5 (-110)
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Cleveland Browns
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–
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+270
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+7 (-110)
-7 (-110)
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O 40.5 (-110)
U 40.5 (-110)
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Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
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–
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-463
+321
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-7.5 (-110)
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O 46 (-110)
U 46 (-110)
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Jets
Bengals
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–
–
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+242
-330
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+7 (-110)
-7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
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+229
-315
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+6.5 (+100)
-6.5 (-120)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
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+287
-407
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+7 (-110)
-7 (-110)
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O 43.5 (-110)
U 43.5 (-110)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-110
-116
|
+1 (-110)
-1 (-110)
|
O 41.5 (-110)
U 41.5 (-110)
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
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+257
-355
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+7 (-110)
-7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
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–
–
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-220
+169
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-4.5 (-110)
+4.5 (-110)
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O 47 (-110)
U 47 (-110)
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Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
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–
–
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+141
-181
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+3.5 (-120)
-3.5 (+100)
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O 50 (-110)
U 50 (-110)
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
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–
–
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+682
-1442
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+14 (-110)
-14 (-110)
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O 47 (-110)
U 47 (-110)
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Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
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-192
+148
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-3.5 (+100)
+3.5 (-120)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
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–
–
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+390
-599
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+10.5 (-110)
-10.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Jacksonville Jaguars vs. Indianapolis Colts on January 05, 2025 at Lucas Oil Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |