Jaguars vs Colts Prediction — AI Finds CAN'T MISS NFL Lines & Props (Jan 05)

Updated: 2024-12-29T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Jacksonville Jaguars (4-12) are set to face the Indianapolis Colts (7-9) on January 5, 2025, at Lucas Oil Stadium in Indianapolis. The Colts are favored by 5.5 points, with the over/under set at 44.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jan 05, 2025

Start Time: 2:00 PM EST​

Venue: Lucas Oil Stadium​

Colts Record: (7-9)

Jaguars Record: (4-12)

OPENING ODDS

JAC Moneyline: +183

IND Moneyline: -222

JAC Spread: +5

IND Spread: -5.0

Over/Under: 43.5

JAC
Betting Trends

  • The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.

IND
Betting Trends

  • The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.

MATCHUP TRENDS

  • Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.

JAC vs. IND
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Jacksonville vs Indianapolis Prediction & Odds:
Free NFL Betting Insights for 1/5/25

The Jacksonville Jaguars and Indianapolis Colts are set to conclude their regular seasons with a divisional showdown at Lucas Oil Stadium. While neither team is playoff-bound, this game offers both squads an opportunity to finish the season on a positive note and build momentum for the future. The Colts enter the matchup with a 7-9 record, aiming to reach .500 with a victory. Their offense has shown flashes of potential, particularly in recent weeks. In Week 17, Indianapolis scored 33 points against the New York Giants, surpassing the Giants’ defensive season average. Quarterback Joe Flacco delivered a solid performance, ranking in the top 10 for Pass Success Rate that week, despite turnovers affecting overall efficiency. On the ground, running back Jonathan Taylor has been a consistent force, accumulating over 1,100 rushing yards this season. The Colts’ rushing attack ranks among the top in the league, averaging 28.9 carries per game, the seventh-highest in the NFL. Defensively, the Colts have had their ups and downs but have managed to keep opponents in check at critical moments. Their ability to generate turnovers and apply pressure on opposing quarterbacks will be crucial against a Jaguars offense that has struggled with consistency. The Jaguars, holding a 4-12 record, are looking to end a disappointing season with a divisional win.

Head coach Doug Pederson has emphasized the importance of finishing strong, noting that a victory would result in a 4-2 record within the AFC South, a silver lining in an otherwise challenging year. Jacksonville’s offense has faced difficulties, particularly in sustaining drives. They rank second-worst in the league in offensive plays per game, averaging 58. The passing game has been middling, with 32.1 attempts per game, ranking 17th in the NFL, while the rushing attack averages 23.8 attempts per game, placing them near the bottom of the league. Defensively, the Jaguars have had notable struggles, especially against the pass. They possess the league’s worst pass defense, allowing the most EPA (Expected Points Added) per dropback to opposing quarterbacks and ranking 25th in defensive Pass Success Rate. This vulnerability could be a focal point for the Colts’ game plan. As the game approaches, both teams will look to exploit each other’s weaknesses. The Colts may focus on their passing attack to take advantage of Jacksonville’s porous secondary, while the Jaguars will aim to establish a balanced offense to challenge Indianapolis’s defense. In this AFC South matchup, the Colts are favored by 5.5 points, with the total points over/under set at 44.5. Given the teams’ recent performances and statistical profiles, this game presents an intriguing contest for both fans and bettors, with the potential for unexpected developments as both teams seek to end their seasons on a high note.

Jacksonville Jaguars NFL Preview

The Jacksonville Jaguars enter their final game of the season with a 4-12 record, looking to end a challenging year on a high note. Despite their struggles, the Jaguars see this matchup against the Colts as an opportunity to gain valuable experience for their young roster and evaluate areas for improvement heading into the offseason. Rookie quarterback Caleb Williams has been a bright spot for Jacksonville, showcasing his potential as a future franchise cornerstone. Williams, the first overall pick in the 2024 NFL Draft, has displayed flashes of brilliance, throwing for over 3,300 yards and 19 touchdowns. His mobility and ability to extend plays have added a dynamic element to the Jaguars’ offense, though inconsistencies and turnovers have limited the unit’s effectiveness. Improving protection for Williams will be a top priority, as the offensive line has struggled to keep him upright against aggressive pass rushes. The Jaguars’ rushing attack, led by Travis Etienne Jr., has been inconsistent, with flashes of success overshadowed by games where the ground game failed to establish itself. Etienne has surpassed 900 rushing yards on the season but has been unable to consistently break through opposing defenses due to a lack of support from the offensive line. Establishing the run early against Indianapolis will be crucial to relieving pressure on Williams and opening up opportunities in the passing game. Defensively, the Jaguars have faced significant challenges, particularly in defending the pass. Jacksonville ranks among the league’s worst in pass defense, allowing a high number of explosive plays through the air. The front seven, led by Josh Allen, has been effective in generating pressure at times, but the lack of consistency in the secondary has hampered the overall defensive effort. Against a veteran quarterback like Joe Flacco, the Jaguars will need to tighten their coverage and create turnovers to keep the game competitive. Special teams have been a mixed bag for Jacksonville. Kicker Brandon McManus has been dependable, converting key field goals when given the opportunity. However, the return game has lacked impact, failing to provide the offense with favorable field position in critical moments. Coverage units will need to be sharp to prevent Indianapolis from gaining an edge in field position. Head coach Doug Pederson has emphasized the importance of finishing the season with a strong performance, highlighting the growth and development of the team’s young players. For the Jaguars, this game represents an opportunity to evaluate their roster, identify areas for improvement, and build confidence heading into the offseason. Keys to victory for Jacksonville include protecting Caleb Williams, establishing a balanced offensive attack, and improving defensive execution to limit the Colts’ productive offense. Special teams will also play a key role in maintaining field position and converting scoring opportunities. While the Jaguars are underdogs, they have the potential to surprise the Colts if they execute effectively and capitalize on mistakes. A win in this divisional matchup would not only boost morale but also provide a positive note to conclude a rebuilding season. Jacksonville’s young core will look to use this game as a stepping stone toward greater success in the future.

The Jacksonville Jaguars (4-12) are set to face the Indianapolis Colts (7-9) on January 5, 2025, at Lucas Oil Stadium in Indianapolis. The Colts are favored by 5.5 points, with the over/under set at 44.5 points. Jacksonville vs Indianapolis AI Prediction: Free NFL Betting Insights for Jan 05. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Indianapolis Colts NFL Preview

The Indianapolis Colts, standing at 7-9, are set to host the Jacksonville Jaguars in their season finale at Lucas Oil Stadium. Aiming to conclude the season with a .500 record, the Colts have shown resilience and growth, particularly in the latter part of the season. Offensively, the Colts have found a rhythm under quarterback Joe Flacco. In Week 17, the offense was prolific, scoring 33 points against the New York Giants, a performance that exceeded the Giants’ defensive season average. Flacco’s command of the offense was evident, as he achieved a top 10 Pass Success Rate for the week, demonstrating his ability to effectively distribute the ball to his playmakers. The ground game has been anchored by running back Jonathan Taylor, who has surpassed 1,100 rushing yards this season. The Colts’ commitment to the run is reflected in their 28.9 carries per game, ranking seventh in the NFL. This balanced offensive approach has been instrumental in controlling the tempo of games and sustaining drives. The offensive line has played a pivotal role in the team’s success, providing strong protection for Flacco and creating running lanes for Taylor. Despite facing some injuries throughout the season, the line’s depth and cohesion have enabled the Colts to maintain their offensive productivity. This unit will be crucial in neutralizing Jacksonville’s defensive front and giving Flacco the time needed to exploit the Jaguars’ weaknesses in coverage. Defensively, the Colts have been a mixed bag, showing the ability to step up in critical moments but also allowing some big plays. Their front seven, led by DeForest Buckner and Shaquille Leonard, has been effective in stopping the run and applying pressure on opposing quarterbacks. The secondary, while capable of creating turnovers, has been inconsistent in coverage, allowing teams to capitalize on breakdowns. Against a Jaguars team with a rookie quarterback, the Colts will look to generate pressure and force Caleb Williams into hurried decisions. Special teams have been a consistent strength for Indianapolis. Kicker Matt Gay has been reliable throughout the season, converting crucial field goals in tight games. The punt and kickoff coverage units have also performed well, helping to tilt the field position battle in the Colts’ favor. Head coach Shane Steichen has emphasized the importance of finishing the season strong, not only for team morale but also to build momentum heading into the offseason. Steichen’s offensive acumen has been evident in the Colts’ improvement in recent weeks, and his ability to adapt the game plan to exploit opponents’ weaknesses has been a key factor in their success. Keys to victory for the Colts include maintaining a balanced offensive approach, using the run game to set up play-action opportunities, and protecting Flacco from Jacksonville’s pass rush. Defensively, they will aim to disrupt Williams’ rhythm, limit big plays, and capitalize on any mistakes by the rookie quarterback. Winning the turnover battle will be critical in what is expected to be a competitive divisional matchup. As the Colts take the field at Lucas Oil Stadium, the home crowd will provide an energetic backdrop for their season finale. A victory over the Jaguars would not only improve their record to 8-9 but also serve as a positive note to conclude a season of growth and development. With a strong foundation in place, the Colts are poised to use this game as a stepping stone toward a more competitive campaign in 2025.

Jacksonville vs. Indianapolis Prop Picks (AI)

Remi is pouring through loads of datapoints on each player. In fact, anytime the Jaguars and Colts play there’s always several intriguing observations to key in on. Not to mention games played at Lucas Oil Stadium in Jan seemingly never follow normal, predictable patterns.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Jacksonville vs. Indianapolis Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every past game between the Jaguars and Colts and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Remi has been most keyed in on the unproportionally assigned emphasis knucklehead sportsbettors regularly put on Indianapolis’s strength factors between a Jaguars team going up against a possibly improved Colts team. We’ve found the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Jacksonville vs Indianapolis picks, computer picks Jaguars vs Colts, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 5 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Jaguars Betting Trends

The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.

Colts Betting Trends

The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.

Jaguars vs. Colts Matchup Trends

Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.

Jacksonville vs. Indianapolis Game Info

Jacksonville vs Indianapolis starts on January 05, 2025 at 2:00 PM EST.

Spread: Indianapolis -5.0
Moneyline: Jacksonville +183, Indianapolis -222
Over/Under: 43.5

Jacksonville: (4-12)  |  Indianapolis: (7-9)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

Both teams share identical ATS records at 8-7, highlighting their unpredictability in covering spreads. This parity adds an intriguing layer to the matchup, as bettors may find it challenging to predict which team will outperform the spread in this divisional clash.

JAC trend: The Jaguars have struggled this season, holding a 4-12 record. Despite their overall performance, they have been competitive against the spread (ATS), achieving an 8-7 ATS record. This indicates that while they have lost games, they have often performed better than expected relative to betting lines.

IND trend: The Colts, with a 7-9 record, have mirrored the Jaguars in ATS performance, also standing at 8-7 ATS. This suggests that Indianapolis has frequently met or exceeded expectations set by oddsmakers, even in games they have lost.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

Jacksonville vs. Indianapolis Odds

Remi is pouring through mountains of stats on each player. In fact, anytime the Jacksonville vs Indianapolis trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable betting trends.

Jacksonville vs Indianapolis Opening Odds

JAC Moneyline: +183
IND Moneyline: -222
JAC Spread: +5
IND Spread: -5.0
Over/Under: 43.5

Jacksonville vs Indianapolis Live Odds

Games PTS ML SPR O/U
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
+148
-185
+3 (+100)
-3 (-120)
O 44.5 (-110)
U 44.5 (-110)
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
+270
-374
+7 (-110)
-7 (-110)
O 40.5 (-110)
U 40.5 (-110)
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
-463
+321
-7.5 (-110)
+7.5 (-110)
O 46 (-110)
U 46 (-110)
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
+242
-330
+7 (-110)
-7 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
+229
-315
+6.5 (+100)
-6.5 (-120)
O 50.5 (-110)
U 50.5 (-110)
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
+287
-407
+7 (-110)
-7 (-110)
O 43.5 (-110)
U 43.5 (-110)
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
-110
-116
+1 (-110)
-1 (-110)
O 41.5 (-110)
U 41.5 (-110)
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
+257
-355
+7 (-110)
-7 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
-220
+169
-4.5 (-110)
+4.5 (-110)
O 47 (-110)
U 47 (-110)
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
+141
-181
+3.5 (-120)
-3.5 (+100)
O 50 (-110)
U 50 (-110)
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
+682
-1442
+14 (-110)
-14 (-110)
O 47 (-110)
U 47 (-110)
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
-192
+148
-3.5 (+100)
+3.5 (-120)
O 44.5 (-110)
U 44.5 (-110)
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
+390
-599
+10.5 (-110)
-10.5 (-110)
O 47.5 (-110)
U 47.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Jacksonville Jaguars vs. Indianapolis Colts on January 05, 2025 at Lucas Oil Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS