Cardinals vs. Rams
Prediction, Odds & Props
Dec 28 | NFL AI Picks

Updated: 2024-12-21T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Cardinals (7-8) are set to face the Los Angeles Rams (9-6) at SoFi Stadium on Saturday, December 28, 2024, at 8:15 PM EST. The Rams, riding a four-game winning streak, aim to solidify their playoff position, while the Cardinals look to rebound from recent losses and keep their slim postseason hopes alive.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Dec 28, 2024

Start Time: 9:10 PM EST​

Venue: SoFi Stadium​

Rams Record: (9-6)

Cardinals Record: (7-8)

OPENING ODDS

ARI Moneyline: +255

LAR Moneyline: -317

ARI Spread: +7

LAR Spread: -7.0

Over/Under: 47.5

ARI
Betting Trends

  • The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

LAR
Betting Trends

  • The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

MATCHUP TRENDS

  • An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

ARI vs. LAR
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Arizona vs Los Angeles Prediction & Odds:
Free NFL Betting Insights for 12/28/24

The Week 17 NFC West showdown between the Arizona Cardinals and the Los Angeles Rams carries significant implications for both teams. The Rams, leading the division with a 9-6 record, are on a four-game winning streak and seek to clinch a playoff berth with a victory. Quarterback Matthew Stafford has been instrumental in their recent success, displaying veteran poise and efficiency. Wide receiver Cooper Kupp continues to be a primary offensive weapon, leading the team in receptions and receiving yards. The Rams’ defense, anchored by defensive tackle Aaron Donald, remains formidable, effectively pressuring opposing quarterbacks and disrupting offensive schemes. The Cardinals, at 7-8, have faced challenges in recent weeks, losing four of their last five games. Quarterback Kyler Murray’s dual-threat capability remains a focal point of their offense, but inconsistencies have hindered their performance. Wide receiver Marquise “Hollywood” Brown has been a key target, providing speed and playmaking ability. Defensively, the Cardinals have struggled to contain high-powered offenses, allowing an average of 23.3 points per game over their last three contests. Betting lines favor the Rams by 5.5 points, with an over/under set at 48.5 points.

The Rams’ recent ATS success contrasts with the Cardinals’ struggles, suggesting a potential advantage for Los Angeles. However, divisional matchups often yield unpredictable outcomes, and the Cardinals’ urgency to keep their playoff hopes alive could inspire a spirited performance. For the Rams, maintaining offensive balance and leveraging their defensive strengths will be key. Establishing the run game to complement Stafford’s passing attack can keep the Cardinals’ defense off balance. Defensively, containing Murray’s mobility and limiting explosive plays will be crucial to securing a victory. The Cardinals must focus on protecting the football and sustaining drives to keep the Rams’ offense off the field. Utilizing Murray’s versatility and involving playmakers like Brown can create opportunities against a stout Rams defense. Defensively, generating pressure on Stafford and tightening coverage in the secondary will be essential to disrupt the Rams’ offensive rhythm. In summary, this matchup features a Rams team looking to secure their playoff position against a Cardinals squad fighting to extend their season. The outcome will hinge on execution in all three phases of the game, with both teams eager to assert dominance in this divisional rivalry.

Arizona Cardinals NFL Preview

The Arizona Cardinals come into this critical Week 17 matchup with a 7-8 record, fighting to keep their slim playoff hopes alive. Head coach Jonathan Gannon has faced a challenging season, balancing the development of young players while trying to remain competitive in the tough NFC West. Quarterback Kyler Murray, returning from an early-season injury, has shown flashes of brilliance but has struggled with consistency. Despite the ups and downs, Murray remains the focal point of the Cardinals’ offense, combining his elite athleticism and quick release to create plays both in the air and on the ground. Offensively, the Cardinals have leaned on wide receiver Marquise “Hollywood” Brown as their top playmaker. Brown leads the team in receptions and receiving yards, providing a deep threat that forces defenses to respect the vertical passing game. Rookie tight end Trey McBride has also emerged as a reliable target in the short and intermediate areas, adding a new dimension to the offense. On the ground, running back James Conner has been steady, rushing for over 850 yards this season and contributing as a pass-catcher out of the backfield. However, the offensive line has struggled to provide consistent protection for Murray, resulting in sacks and hurried throws. Defensively, the Cardinals have had a difficult time containing high-powered offenses. The unit has allowed an average of 24.7 points per game, ranking near the bottom of the league. The pass rush, led by linebacker Zaven Collins, has shown promise but lacks consistency. In the secondary, cornerback Marco Wilson has been tasked with covering opposing teams’ top receivers but has faced challenges against elite talent. The Cardinals’ defense will need to elevate their performance significantly to contain the Rams’ balanced attack. Special teams have been a bright spot for Arizona, with kicker Matt Prater continuing to be one of the most reliable in the league. Prater’s range and accuracy have been critical in keeping the Cardinals competitive in close games. The return game, led by Greg Dortch, has also provided occasional sparks, offering the offense better field position. Heading into the matchup against the Rams, the Cardinals’ game plan will revolve around exploiting mismatches. Offensively, Kyler Murray’s mobility and ability to extend plays will be crucial in avoiding pressure from Aaron Donald and the Rams’ front seven. Finding opportunities to get the ball into the hands of playmakers like Brown and McBride will be key to keeping pace with Los Angeles. Defensively, Arizona must focus on limiting explosive plays by the Rams’ passing attack. Generating turnovers and creating short fields for the offense could swing the momentum in their favor. This game represents a pivotal moment for the Cardinals, as a win keeps their faint playoff hopes alive while also giving their young roster valuable experience in high-stakes football. The challenge will be immense against a Rams team in top form, but with Kyler Murray’s talent and the urgency of the situation, Arizona cannot be counted out. Their ability to execute a near-flawless game plan will determine their fate in this critical divisional matchup.

The Arizona Cardinals (7-8) are set to face the Los Angeles Rams (9-6) at SoFi Stadium on Saturday, December 28, 2024, at 8:15 PM EST. The Rams, riding a four-game winning streak, aim to solidify their playoff position, while the Cardinals look to rebound from recent losses and keep their slim postseason hopes alive. Arizona vs Los Angeles AI Prediction: Free NFL Betting Insights for Dec 28. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Los Angeles Rams NFL Preview

The Los Angeles Rams enter Week 17 with a 9-6 record, leading the NFC West and riding a four-game winning streak that has positioned them favorably for a playoff berth. Under the guidance of head coach Sean McVay, the Rams have demonstrated resilience and adaptability throughout the season. Quarterback Matthew Stafford has been a steadying presence, amassing over 3,800 passing yards and 28 touchdowns. His rapport with wide receiver Cooper Kupp remains a cornerstone of the offense, with Kupp leading the team in receptions, receiving yards, and touchdown catches. The emergence of rookie wideout Puka Nacua has added a new dimension to the passing game, providing Stafford with another reliable target. The Rams’ rushing attack, led by running back Cam Akers, has been effective in complementing the aerial assault. Akers has surpassed 1,000 rushing yards on the season, showcasing a blend of power and agility that keeps defenses honest. The offensive line, despite battling injuries, has provided adequate protection for Stafford and opened running lanes for Akers, contributing to the unit’s overall efficiency. Defensively, the Rams continue to be anchored by perennial All-Pro defensive tackle Aaron Donald, whose disruptive presence in the trenches sets the tone for the unit. Linebacker Ernest Jones leads the team in tackles, demonstrating sideline-to-sideline range and a nose for the football. The secondary, featuring cornerback Jalen Ramsey, has been adept at limiting big plays and creating turnovers, with Ramsey leading the team in interceptions. The defense’s ability to pressure quarterbacks and force mistakes has been instrumental in the Rams’ recent success. Special teams have been a reliable facet of the Rams’ game plan. Kicker Matt Gay has been consistent, converting 90% of his field goal attempts, including several from beyond 50 yards. Punter Johnny Hekker continues to excel in pinning opponents deep, aiding the defense with favorable field position. The return game, spearheaded by Brandon Powell, has provided occasional sparks, contributing to the team’s overall momentum. Facing the Arizona Cardinals in Week 17, the Rams have an opportunity to clinch the division and secure a home playoff game. Offensively, establishing a balanced attack will be key. Utilizing play-action offense to exploit the Cardinals’ struggling secondary could open up big-play opportunities for Matthew Stafford and his receivers. Cooper Kupp will remain the focal point of the passing game, but expect the Rams to involve rookie Puka Nacua and tight end Tyler Higbee to diversify their attack. Cam Akers’ ability to maintain consistent gains on the ground will be critical in controlling the clock and limiting Kyler Murray’s time on the field. Defensively, the Rams must prioritize containing Kyler Murray. His dual-threat ability has historically caused problems for opposing defenses, so maintaining disciplined edge rushing and spying on him with a linebacker could neutralize his scrambling capability. Aaron Donald will be key in generating interior pressure to disrupt Murray’s timing, while Jalen Ramsey’s lockdown coverage will be tasked with neutralizing Marquise Brown. The Rams’ defense should focus on forcing the Cardinals into third-and-long situations, where their pass rush can capitalize. Special teams could provide a critical edge in this matchup. Matt Gay’s accuracy from long range could come into play in what may be a closely contested divisional game. Meanwhile, Johnny Hekker’s punting prowess will aim to pin the Cardinals deep, forcing them to drive long distances against one of the league’s most consistent defenses. In summary, the Rams are positioned to control their own destiny. With a balanced offense, a disruptive defense, and solid special teams, they enter the game as clear favorites. A win not only secures a playoff berth but also builds momentum for what could be a deep postseason run. The Rams’ ability to execute in all phases will determine their success against an Arizona team desperate to keep their playoff hopes alive.

Arizona vs. Los Angeles Prop Picks (AI)

Remi is pouring through loads of data on each line. In fact, anytime the Cardinals and Rams play there’s always several intriguing angles to key in on. Not to mention games played at SoFi Stadium in Dec seemingly never follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Arizona vs. Los Angeles Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over tons of data from every facet between the Cardinals and Rams and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

The Algorithm has been most focused on the growing emphasis knucklehead sportsbettors tend to put on coaching factors between a Cardinals team going up against a possibly healthy Rams team. It appears the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Arizona vs Los Angeles picks, computer picks Cardinals vs Rams, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Cardinals Betting Trends

The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

Rams Betting Trends

The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

Cardinals vs. Rams Matchup Trends

An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

Arizona vs. Los Angeles Game Info

Arizona vs Los Angeles starts on December 28, 2024 at 9:10 PM EST.

Spread: Los Angeles -7.0
Moneyline: Arizona +255, Los Angeles -317
Over/Under: 47.5

Arizona: (7-8)  |  Los Angeles: (9-6)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

ARI trend: The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

LAR trend: The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Arizona vs. Los Angeles Odds

AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the Arizona vs Los Angeles trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable patterns.

Arizona vs Los Angeles Opening Odds

ARI Moneyline: +255
LAR Moneyline: -317
ARI Spread: +7
LAR Spread: -7.0
Over/Under: 47.5

Arizona vs Los Angeles Live Odds

Games PTS ML SPR O/U
Sep 28, 2025 9:31AM EDT
Minnesota Vikings
Pittsburgh Steelers
9/28/25 9:31AM
Vikings
Steelers
-140
+115
-2.5 (-115)
+2.5 (-105)
O 41 (-110)
U 41 (-110)
Sep 28, 2025 1:00PM EDT
Cleveland Browns
Detroit Lions
9/28/25 1PM
Browns
Lions
+400
-550
+10 (-110)
-10 (-110)
O 44.5 (-105)
U 44.5 (-115)
Sep 28, 2025 1:00PM EDT
Los Angeles Chargers
New York Giants
9/28/25 1PM
Chargers
Giants
-285
+230
-6.5 (-105)
+6.5 (-115)
O 44 (-110)
U 44 (-110)
Sep 28, 2025 1:01PM EDT
Tennessee Titans
Houston Texans
9/28/25 1:01PM
Titans
Texans
+300
-375
+7 (-105)
-7 (-115)
O 39 (-110)
U 39 (-110)
Sep 28, 2025 1:01PM EDT
Philadelphia Eagles
Tampa Bay Buccaneers
9/28/25 1:01PM
Eagles
Buccaneers
-190
+160
-3.5 (-105)
+3.5 (-115)
O 44 (-110)
U 44 (-110)
Sep 28, 2025 1:01PM EDT
Washington Commanders
Atlanta Falcons
9/28/25 1:01PM
Commanders
Falcons
+110
-130
+2 (-110)
-2 (-110)
O 43.5 (-110)
U 43.5 (-110)
Sep 28, 2025 1:01PM EDT
New Orleans Saints
Buffalo Bills
9/28/25 1:01PM
Saints
Bills
+800
-1300
+15 (-110)
-15 (-110)
O 48 (-110)
U 48 (-110)
Sep 28, 2025 1:01PM EDT
Carolina Panthers
New England Patriots
9/28/25 1:01PM
Panthers
Patriots
+200
-250
+5.5 (-110)
-5.5 (-110)
O 43 (-110)
U 43 (-110)
Sep 28, 2025 4:06PM EDT
Jacksonville Jaguars
San Francisco 49ers
9/28/25 4:06PM
Jaguars
49ers
+150
-180
+3.5 (-115)
-3.5 (-105)
O 46.5 (-110)
U 46.5 (-110)
Sep 28, 2025 4:06PM EDT
Indianapolis Colts
Los Angeles Rams
9/28/25 4:06PM
Colts
Rams
+160
-190
+3.5 (-110)
-3.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Sep 28, 2025 4:25PM EDT
Baltimore Ravens
Kansas City Chiefs
9/28/25 4:25PM
Ravens
Chiefs
-150
+125
-2.5 (-120)
+2.5 (+100)
O 48.5 (-110)
U 48.5 (-110)
Sep 28, 2025 4:26PM EDT
Chicago Bears
Las Vegas Raiders
9/28/25 4:26PM
Bears
Raiders
+100
-120
+1 (-110)
-1 (-110)
O 48 (-110)
U 48 (-110)
Sep 28, 2025 8:21PM EDT
Green Bay Packers
Dallas Cowboys
9/28/25 8:21PM
Packers
Cowboys
-325
+250
-7 (-105)
+7 (-115)
O 47 (-110)
U 47 (-110)
Sep 29, 2025 7:15PM EDT
New York Jets
Miami Dolphins
9/29/25 7:15PM
Jets
Dolphins
+125
-150
+3 (-115)
-3 (-105)
O 44.5 (-110)
U 44.5 (-110)
Sep 29, 2025 8:15PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:15PM
Bengals
Broncos
+310
-400
+7.5 (-110)
-7.5 (-110)
O 44 (-110)
U 44 (-110)
Oct 2, 2025 8:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 8:16PM
49ers
Rams
+134
-158
+3 (-105)
-3 (-115)
O 47 (-110)
U 47 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Cardinals vs. Los Angeles Rams on December 28, 2024 at SoFi Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS
GB@CLE GB -7 54.3% 4 LOSS
ARI@SF ARI +3 57.7% 6 WIN
KC@NYG PATRICK MAHOMES OVER 230.5 PASS YDS 54.7% 4 WIN
GB@CLE JOE FLACCO OVER 37.5 PASS ATT 56.6% 6 LOSS
MIA@BUF TYREEK HILL OVER 5.5 TOTAL RECEPTIONS 56.8% 6 LOSS
LAC@LV LAC -3 54.9% 4 WIN
TB@HOU BAKER MAYFIELD OVER 1.5 PASS TDS 54.4% 4 WIN
CHI@DET DET -6.5 54.3% 4 WIN
DEN@IND DEN -118 60.1% 10 LOSS
PHI@KC PHI -115 56.7% 6 WIN
SF@NO SF -3 58.8% 8 WIN
SEA@PIT OVER 40 54.9% 4 WIN
CAR@ARI BRYCE YOUNG INTERCEPTIONS UNDER 0.5 56.4% 6 LOSS
DEN@IND JOSH DOWNS RECEPTIONS OVER 3.5 54.7% 4 WIN
ATL@MIN BIJAN ROBINSON RUSH + REC YDS OVER 94.5 53.4% 3 WIN
WAS@GB WAS +3.5 56.5% 6 LOSS
WAS@GB JORDAN LOVE OVER 5.5 RUSH YDS 54.7% 4 WIN
MIN@CHI CALEB WILLIAMS OVER 219.5 PASS YDS 53.4% 3 LOSS
TEN@DEN DEN -8.5 55.3% 5 LOSS
SF@SEA SF -115 54.6% 4 WIN
SF@SEA KENNETH WALKER III UNDER 79.5 RUSH+REC YDS 54.6% 4 WIN
CAR@JAC TANK BIGSBY OVER 10.5 RUSH ATT 56.1% 6 LOSS
KC@LAC JUSTIN HERBERT UNDER 0.5 INT 54.1% 3 WIN
DAL@PHI GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS 54.1% 4 LOSS
KC@PHI JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS 53.90% 5 WIN
KC@PHI DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS 54.40% 6 WIN
KC@PHI PATRICK MAHOMES UNDER 68.3% PASS COMP 55.00% 8 WIN
KC@PHI JALEN HURTS LONGEST RUSH OVER 12.5 YDS 55.60% 8 WIN
BUF@KC DALTON KINCAID OVER 29.5 RECV YDS 55.10% 8 LOSS
WAS@PHI DEVONTA SMITH OVER 3.5 RECEPTIONS 55.80% 8 WIN
BUF@KC JAMES COOK ANYTIME TD 53.00% 5 WIN
LAR@PHI SAQUON BARKLEY UNDER 128 RUSH + REC YDS 53.20% 5 LOSS
BAL@BUF LAMAR JACKSON OVER 54.5 RUSH YDS 54.50% 6 LOSS
HOU@KC C.J. STROUD RUSH YDS UNDER 14.5 53.10% 5 LOSS
WAS@DET JAMESON WILLIAMS RUSH YDS OVER 1.5 53.30% 5 WIN
WAS@DET JARED GOFF PASS COMP % UNDER 72.3 54.30% 6 WIN
MIN@LAR COOPER KUPP ANYTIME TOUCHDOWN 52.60% 3 LOSS
MIN@LAR MATTHEW STAFFORD OVER 21.5 PASS COMP 54.10% 6 LOSS
WAS@TB BRIAN ROBINSON JR OVER 1.5 REC TARGETS 53.50% 5 WIN
WAS@TB BAKER MAYFIELD UNDER 33.5 PASS ATT 54.90% 6 WIN
GB@PHI JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE 54.60% 6 LOSS
LAC@HOU J.K. DOBBINS ANYTIME TD 52.80% 3 LOSS
LAC@HOU LAC -2.5 53.40% 3 LOSS
LAC@HOU JUSTIN HERBERT OVER 19.5 RUSH YDS 53.40% 5 LOSS