Cardinals vs Rams Prediction — AI Finds CAN'T MISS NFL Lines & Props (Dec 28)

Updated: 2024-12-21T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Cardinals (7-8) are set to face the Los Angeles Rams (9-6) at SoFi Stadium on Saturday, December 28, 2024, at 8:15 PM EST. The Rams, riding a four-game winning streak, aim to solidify their playoff position, while the Cardinals look to rebound from recent losses and keep their slim postseason hopes alive.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Dec 28, 2024

Start Time: 9:10 PM EST​

Venue: SoFi Stadium​

Rams Record: (9-6)

Cardinals Record: (7-8)

OPENING ODDS

ARI Moneyline: +255

LAR Moneyline: -317

ARI Spread: +7

LAR Spread: -7.0

Over/Under: 47.5

ARI
Betting Trends

  • The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

LAR
Betting Trends

  • The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

MATCHUP TRENDS

  • An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

ARI vs. LAR
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

LIVE NFL ODDS

NFL ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
325-240
VAULT
NET UNITS
(INCL VIG)
+395.4
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
EXECUTIVE
VS. SPREAD
1593-1364
EXECUTIVE
NET UNITS
(INCL VIG)
+371.9
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Arizona vs Los Angeles Prediction & Odds:
Free NFL Betting Insights for 12/28/24

The Week 17 NFC West showdown between the Arizona Cardinals and the Los Angeles Rams carries significant implications for both teams. The Rams, leading the division with a 9-6 record, are on a four-game winning streak and seek to clinch a playoff berth with a victory. Quarterback Matthew Stafford has been instrumental in their recent success, displaying veteran poise and efficiency. Wide receiver Cooper Kupp continues to be a primary offensive weapon, leading the team in receptions and receiving yards. The Rams’ defense, anchored by defensive tackle Aaron Donald, remains formidable, effectively pressuring opposing quarterbacks and disrupting offensive schemes. The Cardinals, at 7-8, have faced challenges in recent weeks, losing four of their last five games. Quarterback Kyler Murray’s dual-threat capability remains a focal point of their offense, but inconsistencies have hindered their performance. Wide receiver Marquise “Hollywood” Brown has been a key target, providing speed and playmaking ability. Defensively, the Cardinals have struggled to contain high-powered offenses, allowing an average of 23.3 points per game over their last three contests. Betting lines favor the Rams by 5.5 points, with an over/under set at 48.5 points.

The Rams’ recent ATS success contrasts with the Cardinals’ struggles, suggesting a potential advantage for Los Angeles. However, divisional matchups often yield unpredictable outcomes, and the Cardinals’ urgency to keep their playoff hopes alive could inspire a spirited performance. For the Rams, maintaining offensive balance and leveraging their defensive strengths will be key. Establishing the run game to complement Stafford’s passing attack can keep the Cardinals’ defense off balance. Defensively, containing Murray’s mobility and limiting explosive plays will be crucial to securing a victory. The Cardinals must focus on protecting the football and sustaining drives to keep the Rams’ offense off the field. Utilizing Murray’s versatility and involving playmakers like Brown can create opportunities against a stout Rams defense. Defensively, generating pressure on Stafford and tightening coverage in the secondary will be essential to disrupt the Rams’ offensive rhythm. In summary, this matchup features a Rams team looking to secure their playoff position against a Cardinals squad fighting to extend their season. The outcome will hinge on execution in all three phases of the game, with both teams eager to assert dominance in this divisional rivalry.

Arizona Cardinals NFL Preview

The Arizona Cardinals come into this critical Week 17 matchup with a 7-8 record, fighting to keep their slim playoff hopes alive. Head coach Jonathan Gannon has faced a challenging season, balancing the development of young players while trying to remain competitive in the tough NFC West. Quarterback Kyler Murray, returning from an early-season injury, has shown flashes of brilliance but has struggled with consistency. Despite the ups and downs, Murray remains the focal point of the Cardinals’ offense, combining his elite athleticism and quick release to create plays both in the air and on the ground. Offensively, the Cardinals have leaned on wide receiver Marquise “Hollywood” Brown as their top playmaker. Brown leads the team in receptions and receiving yards, providing a deep threat that forces defenses to respect the vertical passing game. Rookie tight end Trey McBride has also emerged as a reliable target in the short and intermediate areas, adding a new dimension to the offense. On the ground, running back James Conner has been steady, rushing for over 850 yards this season and contributing as a pass-catcher out of the backfield. However, the offensive line has struggled to provide consistent protection for Murray, resulting in sacks and hurried throws. Defensively, the Cardinals have had a difficult time containing high-powered offenses. The unit has allowed an average of 24.7 points per game, ranking near the bottom of the league. The pass rush, led by linebacker Zaven Collins, has shown promise but lacks consistency. In the secondary, cornerback Marco Wilson has been tasked with covering opposing teams’ top receivers but has faced challenges against elite talent. The Cardinals’ defense will need to elevate their performance significantly to contain the Rams’ balanced attack. Special teams have been a bright spot for Arizona, with kicker Matt Prater continuing to be one of the most reliable in the league. Prater’s range and accuracy have been critical in keeping the Cardinals competitive in close games. The return game, led by Greg Dortch, has also provided occasional sparks, offering the offense better field position. Heading into the matchup against the Rams, the Cardinals’ game plan will revolve around exploiting mismatches. Offensively, Kyler Murray’s mobility and ability to extend plays will be crucial in avoiding pressure from Aaron Donald and the Rams’ front seven. Finding opportunities to get the ball into the hands of playmakers like Brown and McBride will be key to keeping pace with Los Angeles. Defensively, Arizona must focus on limiting explosive plays by the Rams’ passing attack. Generating turnovers and creating short fields for the offense could swing the momentum in their favor. This game represents a pivotal moment for the Cardinals, as a win keeps their faint playoff hopes alive while also giving their young roster valuable experience in high-stakes football. The challenge will be immense against a Rams team in top form, but with Kyler Murray’s talent and the urgency of the situation, Arizona cannot be counted out. Their ability to execute a near-flawless game plan will determine their fate in this critical divisional matchup.

The Arizona Cardinals (7-8) are set to face the Los Angeles Rams (9-6) at SoFi Stadium on Saturday, December 28, 2024, at 8:15 PM EST. The Rams, riding a four-game winning streak, aim to solidify their playoff position, while the Cardinals look to rebound from recent losses and keep their slim postseason hopes alive. Arizona vs Los Angeles AI Prediction: Free NFL Betting Insights for Dec 28. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Los Angeles Rams NFL Preview

The Los Angeles Rams enter Week 17 with a 9-6 record, leading the NFC West and riding a four-game winning streak that has positioned them favorably for a playoff berth. Under the guidance of head coach Sean McVay, the Rams have demonstrated resilience and adaptability throughout the season. Quarterback Matthew Stafford has been a steadying presence, amassing over 3,800 passing yards and 28 touchdowns. His rapport with wide receiver Cooper Kupp remains a cornerstone of the offense, with Kupp leading the team in receptions, receiving yards, and touchdown catches. The emergence of rookie wideout Puka Nacua has added a new dimension to the passing game, providing Stafford with another reliable target. The Rams’ rushing attack, led by running back Cam Akers, has been effective in complementing the aerial assault. Akers has surpassed 1,000 rushing yards on the season, showcasing a blend of power and agility that keeps defenses honest. The offensive line, despite battling injuries, has provided adequate protection for Stafford and opened running lanes for Akers, contributing to the unit’s overall efficiency. Defensively, the Rams continue to be anchored by perennial All-Pro defensive tackle Aaron Donald, whose disruptive presence in the trenches sets the tone for the unit. Linebacker Ernest Jones leads the team in tackles, demonstrating sideline-to-sideline range and a nose for the football. The secondary, featuring cornerback Jalen Ramsey, has been adept at limiting big plays and creating turnovers, with Ramsey leading the team in interceptions. The defense’s ability to pressure quarterbacks and force mistakes has been instrumental in the Rams’ recent success. Special teams have been a reliable facet of the Rams’ game plan. Kicker Matt Gay has been consistent, converting 90% of his field goal attempts, including several from beyond 50 yards. Punter Johnny Hekker continues to excel in pinning opponents deep, aiding the defense with favorable field position. The return game, spearheaded by Brandon Powell, has provided occasional sparks, contributing to the team’s overall momentum. Facing the Arizona Cardinals in Week 17, the Rams have an opportunity to clinch the division and secure a home playoff game. Offensively, establishing a balanced attack will be key. Utilizing play-action offense to exploit the Cardinals’ struggling secondary could open up big-play opportunities for Matthew Stafford and his receivers. Cooper Kupp will remain the focal point of the passing game, but expect the Rams to involve rookie Puka Nacua and tight end Tyler Higbee to diversify their attack. Cam Akers’ ability to maintain consistent gains on the ground will be critical in controlling the clock and limiting Kyler Murray’s time on the field. Defensively, the Rams must prioritize containing Kyler Murray. His dual-threat ability has historically caused problems for opposing defenses, so maintaining disciplined edge rushing and spying on him with a linebacker could neutralize his scrambling capability. Aaron Donald will be key in generating interior pressure to disrupt Murray’s timing, while Jalen Ramsey’s lockdown coverage will be tasked with neutralizing Marquise Brown. The Rams’ defense should focus on forcing the Cardinals into third-and-long situations, where their pass rush can capitalize. Special teams could provide a critical edge in this matchup. Matt Gay’s accuracy from long range could come into play in what may be a closely contested divisional game. Meanwhile, Johnny Hekker’s punting prowess will aim to pin the Cardinals deep, forcing them to drive long distances against one of the league’s most consistent defenses. In summary, the Rams are positioned to control their own destiny. With a balanced offense, a disruptive defense, and solid special teams, they enter the game as clear favorites. A win not only secures a playoff berth but also builds momentum for what could be a deep postseason run. The Rams’ ability to execute in all phases will determine their success against an Arizona team desperate to keep their playoff hopes alive.

Arizona vs. Los Angeles Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each line. In fact, anytime the Cardinals and Rams play there’s always several intriguing trends to key in on. Not to mention games played at SoFi Stadium in Dec almost always follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Arizona vs. Los Angeles Prediction (AI)

Remi Robot Icon

Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every simulation between the Cardinals and Rams and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

The Algorithm has been most focused on the trending factor human bettors regularly put on coaching factors between a Cardinals team going up against a possibly strong Rams team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Arizona vs Los Angeles picks, computer picks Cardinals vs Rams, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 5 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Cardinals Betting Trends

The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

Rams Betting Trends

The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

Cardinals vs. Rams Matchup Trends

An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

Arizona vs. Los Angeles Game Info

Arizona vs Los Angeles starts on December 28, 2024 at 9:10 PM EST.

Spread: Los Angeles -7.0
Moneyline: Arizona +255, Los Angeles -317
Over/Under: 47.5

Arizona: (7-8)  |  Los Angeles: (9-6)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

An interesting ATS statistic is the Rams’ performance as home favorites. They are favored by 5.5 points in this matchup and have a 3-4 ATS record at home this season. This suggests some variability in their ability to cover the spread when playing at SoFi Stadium, adding an intriguing element for bettors to consider.

ARI trend: The Cardinals have been inconsistent against the spread (ATS) this season, holding a 6-7 ATS record. In their last five games, they have covered the spread only once, reflecting their struggles in meeting betting expectations during this stretch.

LAR trend: The Rams, conversely, have a 7-5 ATS record, demonstrating a more reliable performance for bettors. Notably, they have covered the spread in their last three games, aligning with their current winning streak and indicating a strong finish to the regular season.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Arizona vs. Los Angeles Odds

Remi is pouring through tons of stats on each player. In fact, anytime the Arizona vs Los Angeles trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.

Arizona vs Los Angeles Opening Odds

ARI Moneyline: +255
LAR Moneyline: -317
ARI Spread: +7
LAR Spread: -7.0
Over/Under: 47.5

Arizona vs Los Angeles Live Odds

Games PTS ML SPR O/U
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
+144
-172
+3 (-105)
-3 (-115)
O 44.5 (-112)
U 44.5 (-108)
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
+290
-360
+7 (-114)
-7 (-106)
O 40.5 (-105)
U 40.5 (-115)
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
-430
+340
-7.5 (-110)
+7.5 (-110)
O 46.5 (-105)
U 46.5 (-115)
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
+245
-300
+6.5 (-110)
-6.5 (-110)
O 43.5 (-115)
U 43.5 (-105)
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
+265
-330
+6.5 (-106)
-6.5 (-114)
O 50.5 (-105)
U 50.5 (-115)
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
+270
-335
+7 (-108)
-7 (-112)
O 43.5 (-105)
U 43.5 (-115)
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
-108
-108
+1.5 (-120)
-1.5 (-102)
O 41.5 (-105)
U 41.5 (-115)
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
+280
-350
+7.5 (-122)
-7.5 (+100)
O 44.5 (-114)
U 44.5 (-106)
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
-235
+194
-4.5 (-112)
+4.5 (-108)
O 46.5 (-114)
U 46.5 (-106)
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
+146
-174
+3.5 (-118)
-3.5 (-104)
O 49.5 (-120)
U 49.5 (-102)
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
+750
-1200
+14.5 (-118)
-14.5 (-104)
O 46.5 (-114)
U 46.5 (-106)
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
-174
+146
-3.5 (-104)
+3.5 (-118)
O 44.5 (-115)
U 44.5 (-105)
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
+430
-590
+10.5 (-110)
-10.5 (-110)
O 47.5 (-110)
U 47.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Cardinals vs. Los Angeles Rams on December 28, 2024 at SoFi Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS