Patriots vs Cardinals Prediction — AI Finds CAN'T MISS NFL Lines & Props (Dec 15)

Updated: 2024-12-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New England Patriots (3-10) will face the Arizona Cardinals (6-7) on December 15, 2024, at State Farm Stadium in Glendale, Arizona. The Patriots aim to rebound from a challenging season, while the Cardinals seek to bolster their playoff aspirations.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Dec 15, 2024

Start Time: 5:25 PM EST​

Venue: State Farm Stadium​

Cardinals Record: (6-7)

Patriots Record: (3-10)

OPENING ODDS

NE Moneyline: +202

ARI Moneyline: -248

NE Spread: +5.5

ARI Spread: -5.5

Over/Under: 45.5

NE
Betting Trends

  • The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.

ARI
Betting Trends

  • The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.

MATCHUP TRENDS

  • An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.

NE vs. ARI
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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New England vs Arizona Prediction & Odds:
Free NFL Betting Insights for 12/15/24

The New England Patriots, enduring a 3-10 season, travel to State Farm Stadium to face the Arizona Cardinals, who stand at 6-7 and are vying for a playoff spot. This Week 15 matchup presents contrasting narratives: the Patriots aim to salvage pride and assess future prospects, while the Cardinals seek to strengthen their postseason bid. Offensively, the Patriots have faced significant challenges. Their passing game ranks last in the league, averaging 171.5 yards per game, reflecting struggles in quarterback play and receiver production. The ground attack, led by running back Rhamondre Stevenson, offers some consistency, averaging 119.5 yards per game. However, the offense’s overall output is concerning, with a mere 17 points per game, placing them near the bottom of the league. Defensively, New England has been middling, allowing 351.8 yards and 23.6 points per game. The unit has been inconsistent, showing flashes of competence but often faltering in critical moments. Their ability to contain Arizona’s dynamic offense will be pivotal in this contest. The Cardinals’ offense, orchestrated by quarterback Kyler Murray, averages 358.3 yards and 22.2 points per game. Murray’s dual-threat capability, combined with a solid receiving corps and a strong running game averaging 141.4 yards per game, makes Arizona a formidable opponent. Their balanced attack will test the Patriots’ defensive resilience.

Defensively, Arizona allows 352.5 yards and 21.6 points per game. Their defense has been more effective than New England’s, particularly in scoring defense, ranking 11th in the league. The Cardinals’ ability to pressure the quarterback and create turnovers could be decisive against a struggling Patriots offense. Special teams could play a significant role. Field position battles and the reliability of kickers in high-pressure situations may influence the game’s outcome. Both teams will need to execute effectively in this phase to gain any possible advantage. Historically, the Patriots have dominated this matchup, with the Cardinals going 1-7 ATS in their last eight games against New England. This trend may provide a psychological edge for the Patriots, though each game presents its own unique challenges. In summary, this Week 15 matchup between the Patriots and Cardinals is a critical juncture for both teams. New England seeks to salvage pride and assess future prospects, while Arizona aims to strengthen its postseason bid. The game’s outcome will hinge on key factors such as quarterback play, defensive resilience, and special teams execution. Fans can anticipate a hard-fought contest as both teams vie for a much-needed victory.

New England Patriots NFL Preview

The New England Patriots head into Week 15 with a disappointing 3-10 record as they prepare to face the Arizona Cardinals at State Farm Stadium. It has been a challenging season for the Patriots, characterized by offensive struggles, inconsistent play, and a lack of results. Head coach Bill Belichick, known for his ability to adapt and strategize, faces one of the toughest seasons of his career, as he looks to guide his team through adversity and evaluate talent for the future. Offensively, the Patriots have been among the least productive teams in the league, averaging just 17 points per game. The passing attack has been particularly underwhelming, ranking last in the NFL with only 171.5 yards per game. Quarterback play has been a major issue, with inconsistent performances from Mac Jones and a lack of chemistry with the receiving corps. Wide receivers have struggled to create separation, and tight ends, including Hunter Henry, have not been utilized effectively. The running game, led by Rhamondre Stevenson, has been the lone bright spot, averaging 119.5 yards per game. Stevenson’s ability to break tackles and contribute as a receiver out of the backfield has provided some stability to an otherwise stagnant offense. Defensively, the Patriots have been inconsistent, allowing 23.6 points per game. The front seven, featuring Matthew Judon and Christian Barmore, has been effective at times in generating pressure, but the secondary has been vulnerable to big plays. Injuries and communication breakdowns have contributed to the defense’s struggles, and the unit has been unable to consistently get off the field on third downs. Against the Cardinals, the defense will need to focus on containing Kyler Murray and limiting explosive plays from Arizona’s versatile offense. Special teams have been another area of concern for New England. While kicker Chad Ryland has been reliable on shorter attempts, his struggles from longer distances have cost the team valuable points. The return game has been underwhelming, and coverage units have occasionally allowed significant yardage, putting the defense in difficult positions. As the Patriots prepare for this matchup, their focus will likely center on simplifying the offensive game plan and leaning on their ground attack. Establishing Stevenson early in the game and using play-action passes to create opportunities downfield could help alleviate pressure on the quarterback. Defensively, the Patriots will need to find ways to disrupt Kyler Murray’s rhythm, whether through disciplined pass rush lanes or creative blitz packages. This game also represents an opportunity for New England to evaluate young players and experiment with different lineups. With the playoffs out of reach, the focus shifts to player development and identifying building blocks for the future. A strong performance against the Cardinals could serve as a morale boost and provide some optimism for the franchise moving forward. Ultimately, the Patriots will need to execute a near-perfect game plan to overcome the Cardinals. Limiting turnovers, maximizing red-zone opportunities, and containing Arizona’s dynamic offense will be critical. While the odds may not be in their favor, the Patriots will aim to compete and prove that they can rise to the occasion, even in a challenging season.

The New England Patriots (3-10) will face the Arizona Cardinals (6-7) on December 15, 2024, at State Farm Stadium in Glendale, Arizona. The Patriots aim to rebound from a challenging season, while the Cardinals seek to bolster their playoff aspirations. New England vs Arizona AI Prediction: Free NFL Betting Insights for Dec 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Arizona Cardinals NFL Preview

The Arizona Cardinals enter Week 15 with a 6-7 record, hosting the New England Patriots at State Farm Stadium. The Cardinals are in the thick of the playoff race, and a victory against the struggling Patriots is crucial to keep their postseason hopes alive. Head coach Kliff Kingsbury has emphasized the importance of focus and execution as the team approaches this pivotal game. Offensively, the Cardinals are led by quarterback Kyler Murray, whose dual-threat ability makes him a constant challenge for defenses. Murray has thrown for 3,200 yards and 22 touchdowns this season, while also contributing 500 yards and four touchdowns on the ground. His mobility extends plays and creates opportunities for big gains. The receiving corps, featuring DeAndre Hopkins and Rondale Moore, provides reliable targets, with Hopkins leading the team in receptions and receiving yards. The ground game, spearheaded by James Conner, averages 141.4 yards per game, ranking sixth in the league. Conner’s physical running style complements Murray’s agility, creating a balanced offensive attack. Defensively, Arizona has been solid, allowing 352.5 yards and 21.6 points per game. The pass rush, led by Chandler Jones and J.J. Watt, has been effective in pressuring opposing quarterbacks, combining for 18 sacks this season. The secondary, anchored by Budda Baker, has been opportunistic, recording 12 interceptions. The defense’s ability to disrupt the Patriots’ offense, which has struggled this season, will be a key factor in the game. Special teams have been a reliable component for the Cardinals. Kicker Matt Prater has converted 85% of his field goal attempts, including several from beyond 50 yards. The return game, with Eno Benjamin handling kickoffs and punts, has provided favorable field position on multiple occasions. Maintaining excellence in this phase will be important as the Cardinals look to capitalize on every opportunity. As the Cardinals prepare for this matchup, their focus will be on executing their game plan and not underestimating the Patriots despite their record. Offensively, establishing the run to set up play-action passes could exploit New England’s defense. Defensively, containing the Patriots’ ground game and forcing them into passing situations will allow Arizona’s pass rush to be more effective. Winning the turnover battle and controlling the clock will also be crucial elements in securing a victory. The Cardinals will also look to leverage their home-field advantage, as playing at State Farm Stadium has historically been a boost for the team. The crowd’s energy can play a significant role in disrupting the Patriots’ offensive communication, especially with a struggling quarterback at the helm. Arizona’s ability to feed off the home crowd and maintain a high level of intensity throughout the game will be pivotal. From a coaching perspective, Kliff Kingsbury will aim to maintain a balanced offensive attack, utilizing Kyler Murray’s mobility to keep the Patriots’ defense off balance. Designing plays that capitalize on mismatches in the secondary, particularly involving DeAndre Hopkins, will be a focal point. On defense, the Cardinals’ strategy will likely center on containing Rhamondre Stevenson, the Patriots’ most reliable offensive weapon. Limiting his effectiveness will force New England to rely on their struggling passing game, giving Arizona’s pass rush opportunities to disrupt the backfield. This game is a critical opportunity for Arizona to stay in the playoff hunt. A win would improve their record to 7-7, keeping them firmly in contention for a wildcard spot in the competitive NFC. Conversely, a loss could derail their postseason aspirations and create additional pressure in the remaining weeks of the season. With so much at stake, the Cardinals are expected to approach this game with urgency and focus. Ultimately, the Cardinals are in a strong position to secure a victory if they execute their game plan effectively. With a more dynamic offense, a solid defense, and the motivation to keep their playoff hopes alive, Arizona has all the tools necessary to overcome a struggling Patriots team. For the Cardinals, this game represents not only a chance to improve their playoff positioning but also an opportunity to build momentum heading into the final stretch of the regular season.

New England vs. Arizona Prop Picks (AI)

AI algorithm Remi is pouring through loads of datapoints on each team. In fact, anytime the Patriots and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at State Farm Stadium in Dec rarely follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

New England vs. Arizona Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every simulation between the Patriots and Cardinals and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the growing factor knucklehead sportsbettors tend to put on Arizona’s strength factors between a Patriots team going up against a possibly rested Cardinals team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI New England vs Arizona picks, computer picks Patriots vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 5 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Patriots Betting Trends

The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.

Cardinals Betting Trends

The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.

Patriots vs. Cardinals Matchup Trends

An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.

New England vs. Arizona Game Info

New England vs Arizona starts on December 15, 2024 at 5:25 PM EST.

Spread: Arizona -5.5
Moneyline: New England +202, Arizona -248
Over/Under: 45.5

New England: (3-10)  |  Arizona: (6-7)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.

NE trend: The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.

ARI trend: The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

New England vs. Arizona Odds

Remi is pouring through loads of data points on each line. In fact, anytime the New England vs Arizona trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.

New England vs Arizona Opening Odds

NE Moneyline: +202
ARI Moneyline: -248
NE Spread: +5.5
ARI Spread: -5.5
Over/Under: 45.5

New England vs Arizona Live Odds

Games PTS ML SPR O/U
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
+142
-165
+3 (-110)
-3 (-110)
O 45 (-110)
U 45 (-110)
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
+290
-360
+7 (-110)
-7 (-110)
O 40.5 (-110)
U 40.5 (-110)
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
-400
+320
-7.5 (-110)
+7.5 (-110)
O 45.5 (-110)
U 45.5 (-110)
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
+250
-300
+6.5 (-105)
-6.5 (-115)
O 44.5 (-105)
U 44.5 (-115)
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
+265
-325
+7 (-120)
-7 (+100)
O 50 (-110)
U 50 (-110)
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
+290
-360
+7 (-105)
-7 (-115)
O 43.5 (-115)
U 43.5 (-105)
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
-110
-106
-1.5 (-104)
+1.5 (-118)
O 41.5 (-115)
U 41.5 (-105)
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
+280
-350
+7 (-110)
-7 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
-220
+184
-4.5 (-112)
+4.5 (-108)
O 47.5 (-105)
U 47.5 (-115)
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
+146
-170
+3 (+100)
-3 (-120)
O 49.5 (-110)
U 49.5 (-110)
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
+750
-1200
+14 (-110)
-14 (-110)
O 47 (-110)
U 47 (-110)
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
-185
+159
-3.5 (-105)
+3.5 (-115)
O 45 (-113)
U 45 (-107)
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
+465
-630
+10.5 (-115)
-10.5 (-105)
O 48.5 (-110)
U 48.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New England Patriots vs. Arizona Cardinals on December 15, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS