Patriots vs. Cardinals
Prediction, Odds & Props
Dec 15 | NFL AI Picks
Updated: 2024-12-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The New England Patriots (3-10) will face the Arizona Cardinals (6-7) on December 15, 2024, at State Farm Stadium in Glendale, Arizona. The Patriots aim to rebound from a challenging season, while the Cardinals seek to bolster their playoff aspirations.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Dec 15, 2024
Start Time: 5:25 PM EST​
Venue: State Farm Stadium​
Cardinals Record: (6-7)
Patriots Record: (3-10)
OPENING ODDS
NE Moneyline: +202
ARI Moneyline: -248
NE Spread: +5.5
ARI Spread: -5.5
Over/Under: 45.5
NE
Betting Trends
- The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.
ARI
Betting Trends
- The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.
MATCHUP TRENDS
- An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.
NE vs. ARI
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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New England vs Arizona Prediction & Odds:
Free NFL Betting Insights for 12/15/24
Defensively, Arizona allows 352.5 yards and 21.6 points per game. Their defense has been more effective than New England’s, particularly in scoring defense, ranking 11th in the league. The Cardinals’ ability to pressure the quarterback and create turnovers could be decisive against a struggling Patriots offense. Special teams could play a significant role. Field position battles and the reliability of kickers in high-pressure situations may influence the game’s outcome. Both teams will need to execute effectively in this phase to gain any possible advantage. Historically, the Patriots have dominated this matchup, with the Cardinals going 1-7 ATS in their last eight games against New England. This trend may provide a psychological edge for the Patriots, though each game presents its own unique challenges. In summary, this Week 15 matchup between the Patriots and Cardinals is a critical juncture for both teams. New England seeks to salvage pride and assess future prospects, while Arizona aims to strengthen its postseason bid. The game’s outcome will hinge on key factors such as quarterback play, defensive resilience, and special teams execution. Fans can anticipate a hard-fought contest as both teams vie for a much-needed victory.
Patriots Wednesday injury report: https://t.co/DBAHmFqcvS pic.twitter.com/1SjywT98iB
— New England Patriots (@Patriots) December 11, 2024
New England Patriots NFL Preview
The New England Patriots head into Week 15 with a disappointing 3-10 record as they prepare to face the Arizona Cardinals at State Farm Stadium. It has been a challenging season for the Patriots, characterized by offensive struggles, inconsistent play, and a lack of results. Head coach Bill Belichick, known for his ability to adapt and strategize, faces one of the toughest seasons of his career, as he looks to guide his team through adversity and evaluate talent for the future. Offensively, the Patriots have been among the least productive teams in the league, averaging just 17 points per game. The passing attack has been particularly underwhelming, ranking last in the NFL with only 171.5 yards per game. Quarterback play has been a major issue, with inconsistent performances from Mac Jones and a lack of chemistry with the receiving corps. Wide receivers have struggled to create separation, and tight ends, including Hunter Henry, have not been utilized effectively. The running game, led by Rhamondre Stevenson, has been the lone bright spot, averaging 119.5 yards per game. Stevenson’s ability to break tackles and contribute as a receiver out of the backfield has provided some stability to an otherwise stagnant offense. Defensively, the Patriots have been inconsistent, allowing 23.6 points per game. The front seven, featuring Matthew Judon and Christian Barmore, has been effective at times in generating pressure, but the secondary has been vulnerable to big plays. Injuries and communication breakdowns have contributed to the defense’s struggles, and the unit has been unable to consistently get off the field on third downs. Against the Cardinals, the defense will need to focus on containing Kyler Murray and limiting explosive plays from Arizona’s versatile offense. Special teams have been another area of concern for New England. While kicker Chad Ryland has been reliable on shorter attempts, his struggles from longer distances have cost the team valuable points. The return game has been underwhelming, and coverage units have occasionally allowed significant yardage, putting the defense in difficult positions. As the Patriots prepare for this matchup, their focus will likely center on simplifying the offensive game plan and leaning on their ground attack. Establishing Stevenson early in the game and using play-action passes to create opportunities downfield could help alleviate pressure on the quarterback. Defensively, the Patriots will need to find ways to disrupt Kyler Murray’s rhythm, whether through disciplined pass rush lanes or creative blitz packages. This game also represents an opportunity for New England to evaluate young players and experiment with different lineups. With the playoffs out of reach, the focus shifts to player development and identifying building blocks for the future. A strong performance against the Cardinals could serve as a morale boost and provide some optimism for the franchise moving forward. Ultimately, the Patriots will need to execute a near-perfect game plan to overcome the Cardinals. Limiting turnovers, maximizing red-zone opportunities, and containing Arizona’s dynamic offense will be critical. While the odds may not be in their favor, the Patriots will aim to compete and prove that they can rise to the occasion, even in a challenging season.

Credit: USA TODAY/IMAGN
Arizona Cardinals NFL Preview
The Arizona Cardinals enter Week 15 with a 6-7 record, hosting the New England Patriots at State Farm Stadium. The Cardinals are in the thick of the playoff race, and a victory against the struggling Patriots is crucial to keep their postseason hopes alive. Head coach Kliff Kingsbury has emphasized the importance of focus and execution as the team approaches this pivotal game. Offensively, the Cardinals are led by quarterback Kyler Murray, whose dual-threat ability makes him a constant challenge for defenses. Murray has thrown for 3,200 yards and 22 touchdowns this season, while also contributing 500 yards and four touchdowns on the ground. His mobility extends plays and creates opportunities for big gains. The receiving corps, featuring DeAndre Hopkins and Rondale Moore, provides reliable targets, with Hopkins leading the team in receptions and receiving yards. The ground game, spearheaded by James Conner, averages 141.4 yards per game, ranking sixth in the league. Conner’s physical running style complements Murray’s agility, creating a balanced offensive attack. Defensively, Arizona has been solid, allowing 352.5 yards and 21.6 points per game. The pass rush, led by Chandler Jones and J.J. Watt, has been effective in pressuring opposing quarterbacks, combining for 18 sacks this season. The secondary, anchored by Budda Baker, has been opportunistic, recording 12 interceptions. The defense’s ability to disrupt the Patriots’ offense, which has struggled this season, will be a key factor in the game. Special teams have been a reliable component for the Cardinals. Kicker Matt Prater has converted 85% of his field goal attempts, including several from beyond 50 yards. The return game, with Eno Benjamin handling kickoffs and punts, has provided favorable field position on multiple occasions. Maintaining excellence in this phase will be important as the Cardinals look to capitalize on every opportunity. As the Cardinals prepare for this matchup, their focus will be on executing their game plan and not underestimating the Patriots despite their record. Offensively, establishing the run to set up play-action passes could exploit New England’s defense. Defensively, containing the Patriots’ ground game and forcing them into passing situations will allow Arizona’s pass rush to be more effective. Winning the turnover battle and controlling the clock will also be crucial elements in securing a victory. The Cardinals will also look to leverage their home-field advantage, as playing at State Farm Stadium has historically been a boost for the team. The crowd’s energy can play a significant role in disrupting the Patriots’ offensive communication, especially with a struggling quarterback at the helm. Arizona’s ability to feed off the home crowd and maintain a high level of intensity throughout the game will be pivotal. From a coaching perspective, Kliff Kingsbury will aim to maintain a balanced offensive attack, utilizing Kyler Murray’s mobility to keep the Patriots’ defense off balance. Designing plays that capitalize on mismatches in the secondary, particularly involving DeAndre Hopkins, will be a focal point. On defense, the Cardinals’ strategy will likely center on containing Rhamondre Stevenson, the Patriots’ most reliable offensive weapon. Limiting his effectiveness will force New England to rely on their struggling passing game, giving Arizona’s pass rush opportunities to disrupt the backfield. This game is a critical opportunity for Arizona to stay in the playoff hunt. A win would improve their record to 7-7, keeping them firmly in contention for a wildcard spot in the competitive NFC. Conversely, a loss could derail their postseason aspirations and create additional pressure in the remaining weeks of the season. With so much at stake, the Cardinals are expected to approach this game with urgency and focus. Ultimately, the Cardinals are in a strong position to secure a victory if they execute their game plan effectively. With a more dynamic offense, a solid defense, and the motivation to keep their playoff hopes alive, Arizona has all the tools necessary to overcome a struggling Patriots team. For the Cardinals, this game represents not only a chance to improve their playoff positioning but also an opportunity to build momentum heading into the final stretch of the regular season.
The top tracks from Week 14 ⏯️ pic.twitter.com/YMViUKhPbq
— Arizona Cardinals (@AZCardinals) December 11, 2024
New England vs. Arizona Prop Picks (AI)
New England vs. Arizona Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every past game between the Patriots and Cardinals and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the growing factor knucklehead sportsbettors often put on coaching factors between a Patriots team going up against a possibly healthy Cardinals team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI New England vs Arizona picks, computer picks Patriots vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Patriots Betting Trends
The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.
Cardinals Betting Trends
The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.
Patriots vs. Cardinals Matchup Trends
An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.
New England vs. Arizona Game Info
What time does New England vs Arizona start on December 15, 2024?
New England vs Arizona starts on December 15, 2024 at 5:25 PM EST.
Where is New England vs Arizona being played?
Venue: State Farm Stadium.
What are the opening odds for New England vs Arizona?
Spread: Arizona -5.5
Moneyline: New England +202, Arizona -248
Over/Under: 45.5
What are the records for New England vs Arizona?
New England: (3-10) Â |Â Arizona: (6-7)
What is the AI best bet for New England vs Arizona?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are New England vs Arizona trending bets?
An interesting ATS statistic is that the Cardinals are 1-7 in spread bets in their last eight games against the Patriots, indicating a favorable trend for New England in this matchup.
What are New England trending bets?
NE trend: The Patriots have struggled against the spread (ATS) recently, posting a 3-7 record in their last 10 games. Their inconsistent performance has made them a challenging team for bettors, as they have failed to cover in several key matchups.
What are Arizona trending bets?
ARI trend: The Cardinals have fared better ATS, holding a 6-6 record this season. Despite their overall losing record, they have managed to cover the spread in some games, particularly when playing as underdogs.
Where can I find AI Picks for New England vs Arizona?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
New England vs. Arizona Odds
AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the New England vs Arizona trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable patterns.
New England vs Arizona Opening Odds
NE Moneyline:
+202 ARI Moneyline: -248
NE Spread: +5.5
ARI Spread: -5.5
Over/Under: 45.5
New England vs Arizona Live Odds
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O 48 (-110)
U 48 (-110)
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U 43 (-110)
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U 49.5 (-110)
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+100
-120
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+1 (-110)
-1 (-110)
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O 48 (-110)
U 48 (-110)
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O 47 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers New England Patriots vs. Arizona Cardinals on December 15, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |
GB@CLE | GB -7 | 54.3% | 4 | LOSS |
ARI@SF | ARI +3 | 57.7% | 6 | WIN |
KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
LAC@LV | LAC -3 | 54.9% | 4 | WIN |
TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
PHI@KC | PHI -115 | 56.7% | 6 | WIN |
SF@NO | SF -3 | 58.8% | 8 | WIN |
SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
SF@SEA | SF -115 | 54.6% | 4 | WIN |
SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |