49ers vs Packers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 24)
Updated: 2024-11-17T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On November 24, 2024, the San Francisco 49ers (5-5) will face the Green Bay Packers (7-3) at Lambeau Field in Green Bay, Wisconsin. This Week 12 matchup is crucial for both teams as they vie for playoff positioning in the NFC.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 24, 2024
Start Time: 5:25 PM EST
Venue: Lambeau Field
Packers Record: (7-3)
49ers Record: (5-5)
OPENING ODDS
SF Moneyline: +118
GB Moneyline: -139
SF Spread: +2.5
GB Spread: -2.5
Over/Under: 47.5
SF
Betting Trends
- The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
GB
Betting Trends
- The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
MATCHUP TRENDS
- Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
SF vs. GB
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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San Francisco vs Green Bay Prediction & Odds:
Free NFL Betting Insights for 11/24/24
The defense has been opportunistic, creating turnovers and applying consistent pressure on opposing quarterbacks. Green Bay’s home-field advantage at Lambeau Field has been a significant factor, with the team performing well in front of their home crowd. Key factors in this matchup include the health and availability of 49ers’ key players, particularly Brock Purdy and Nick Bosa. The Packers’ ability to exploit San Francisco’s potential defensive vulnerabilities and maintain their offensive efficiency will also be crucial. Special teams could play a pivotal role, as both teams have had issues in this area. Given the current form and statistical trends, the Packers appear to have the upper hand, but the 49ers’ resilience and desperation for a win could make this a closely contested game.
Check out birthday boy Fred Warner's top plays from the 2024 season (so far) 🎥#SFvsGB on FOX up next pic.twitter.com/IAdk72bPTd
— San Francisco 49ers (@49ers) November 19, 2024
San Francisco 49ers NFL Preview
The San Francisco 49ers are facing a challenging season, currently holding a 5-5 record and dealing with a series of setbacks. The loss to the Seattle Seahawks highlighted their offensive struggles and injury concerns. Quarterback Brock Purdy is dealing with right shoulder soreness, rendering his status uncertain for the upcoming game. If Purdy is unable to play, the team may turn to backups Brandon Allen or Joshua Dobbs. The running game, led by Christian McCaffrey, has shown flashes of potential but has been inconsistent, failing to provide the necessary balance to the offense. The receiving corps, featuring George Kittle and Deebo Samuel, has been productive, but injuries have limited their impact. Defensively, the 49ers have been formidable, limiting opponents to an average of 19.5 points per game. However, injuries to key players like Nick Bosa (hip/oblique) could impact their performance. The secondary has been effective in limiting big plays, and the pass rush has been relentless, contributing to the team’s overall defensive success. Special teams have been reliable, with kicker Robbie Gould providing stability and the return units contributing positively to field position. The coaching staff, led by head coach Kyle Shanahan, has faced scrutiny for the team’s performance and decision-making. The focus for the 49ers will be on salvaging the remainder of the season and evaluating talent for the future. This game against the Packers presents an opportunity to break the losing streak and regain some confidence, though the challenges are substantial given the current state of the team.
Credit: USA TODAY/IMAGN
Green Bay Packers NFL Preview
The Green Bay Packers enter this matchup with a 7-3 record, showcasing a balanced and efficient team on both sides of the ball. Quarterback Jordan Love has been a revelation, leading an offense that ranks among the top in the league in both passing and rushing yards per game. The running game, led by Aaron Jones and A.J. Dillon, has provided a solid foundation, allowing the Packers to control the clock and dictate the pace of the game. The receiving corps, featuring Davante Adams and emerging talents like Jayden Reed, has been productive, creating mismatches and stretching opposing defenses. Defensively, the Packers have been opportunistic, creating turnovers and applying consistent pressure on opposing quarterbacks. The secondary, anchored by Jaire Alexander, has been effective in limiting big plays and securing interceptions. The pass rush, led by Rashan Gary and Preston Smith, has been relentless, contributing to the team’s overall defensive success. Special teams have been reliable, with kicker Mason Crosby providing stability and the return units contributing positively to field position. The coaching staff, led by head coach Matt LaFleur, has instilled a winning culture and strategic acumen, contributing to the team’s success. The focus for the Packers will be on maintaining their momentum and securing a playoff berth. This game against the 49ers presents an opportunity to solidify their position in the NFC and continue their upward trajectory.
All righty then.
— Green Bay Packers (@packers) November 20, 2024
📬: @mikespofford
San Francisco vs. Green Bay Prop Picks (AI)
San Francisco vs. Green Bay Prediction (AI)
Remi, our AI sports wizard, has been pouring over tons of data from every angle between the 49ers and Packers and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.
Remi has been most watching on the linear correlation of weight human bettors regularly put on coaching factors between a 49ers team going up against a possibly unhealthy Packers team. We’ve found the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI San Francisco vs Green Bay picks, computer picks 49ers vs Packers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
49ers Betting Trends
The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
Packers Betting Trends
The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
49ers vs. Packers Matchup Trends
Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
San Francisco vs. Green Bay Game Info
What time does San Francisco vs Green Bay start on November 24, 2024?
San Francisco vs Green Bay starts on November 24, 2024 at 5:25 PM EST.
Where is San Francisco vs Green Bay being played?
Venue: Lambeau Field.
What are the opening odds for San Francisco vs Green Bay?
Spread: Green Bay -2.5
Moneyline: San Francisco +118, Green Bay -139
Over/Under: 47.5
What are the records for San Francisco vs Green Bay?
San Francisco: (5-5) | Green Bay: (7-3)
What is the AI best bet for San Francisco vs Green Bay?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are San Francisco vs Green Bay trending bets?
Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
What are San Francisco trending bets?
SF trend: The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
What are Green Bay trending bets?
GB trend: The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
Where can I find AI Picks for San Francisco vs Green Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
San Francisco vs. Green Bay Odds
AI algorithm Remi is pouring through loads of data points on each team. In fact, anytime the San Francisco vs Green Bay trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.
San Francisco vs Green Bay Opening Odds
SF Moneyline:
+118 GB Moneyline: -139
SF Spread: +2.5
GB Spread: -2.5
Over/Under: 47.5
San Francisco vs Green Bay Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
|
–
–
|
+144
-172
|
+3 (-105)
-3 (-115)
|
O 44.5 (-112)
U 44.5 (-108)
|
|
|
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
|
–
–
|
+290
-360
|
+7 (-114)
-7 (-106)
|
O 40.5 (-105)
U 40.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-430
+340
|
-7.5 (-110)
+7.5 (-110)
|
O 46.5 (-105)
U 46.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
|
+245
-300
|
+6.5 (-110)
-6.5 (-110)
|
O 43.5 (-115)
U 43.5 (-105)
|
|
|
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+265
-330
|
+6.5 (-106)
-6.5 (-114)
|
O 50.5 (-105)
U 50.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+270
-335
|
+7 (-108)
-7 (-112)
|
O 43.5 (-105)
U 43.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-108
-108
|
+1.5 (-120)
-1.5 (-102)
|
O 41.5 (-105)
U 41.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+280
-350
|
+7.5 (-122)
-7.5 (+100)
|
O 44.5 (-114)
U 44.5 (-106)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-235
+194
|
-4.5 (-112)
+4.5 (-108)
|
O 46.5 (-114)
U 46.5 (-106)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+146
-174
|
+3.5 (-118)
-3.5 (-104)
|
O 49.5 (-120)
U 49.5 (-102)
|
|
|
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+750
-1200
|
+14.5 (-118)
-14.5 (-104)
|
O 46.5 (-114)
U 46.5 (-106)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-174
+146
|
-3.5 (-104)
+3.5 (-118)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+430
-590
|
+10.5 (-110)
-10.5 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Francisco 49ers vs. Green Bay Packers on November 24, 2024 at Lambeau Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |