49ers vs. Packers
Prediction, Odds & Props
Nov 24 | NFL AI Picks
Updated: 2024-11-17T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On November 24, 2024, the San Francisco 49ers (5-5) will face the Green Bay Packers (7-3) at Lambeau Field in Green Bay, Wisconsin. This Week 12 matchup is crucial for both teams as they vie for playoff positioning in the NFC.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 24, 2024
Start Time: 5:25 PM EST​
Venue: Lambeau Field​
Packers Record: (7-3)
49ers Record: (5-5)
OPENING ODDS
SF Moneyline: +118
GB Moneyline: -139
SF Spread: +2.5
GB Spread: -2.5
Over/Under: 47.5
SF
Betting Trends
- The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
GB
Betting Trends
- The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
MATCHUP TRENDS
- Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
SF vs. GB
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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San Francisco vs Green Bay Prediction & Odds:
Free NFL Betting Insights for 11/24/24
The defense has been opportunistic, creating turnovers and applying consistent pressure on opposing quarterbacks. Green Bay’s home-field advantage at Lambeau Field has been a significant factor, with the team performing well in front of their home crowd. Key factors in this matchup include the health and availability of 49ers’ key players, particularly Brock Purdy and Nick Bosa. The Packers’ ability to exploit San Francisco’s potential defensive vulnerabilities and maintain their offensive efficiency will also be crucial. Special teams could play a pivotal role, as both teams have had issues in this area. Given the current form and statistical trends, the Packers appear to have the upper hand, but the 49ers’ resilience and desperation for a win could make this a closely contested game.
Check out birthday boy Fred Warner's top plays from the 2024 season (so far) 🎥#SFvsGB on FOX up next pic.twitter.com/IAdk72bPTd
— San Francisco 49ers (@49ers) November 19, 2024
San Francisco 49ers NFL Preview
The San Francisco 49ers are facing a challenging season, currently holding a 5-5 record and dealing with a series of setbacks. The loss to the Seattle Seahawks highlighted their offensive struggles and injury concerns. Quarterback Brock Purdy is dealing with right shoulder soreness, rendering his status uncertain for the upcoming game. If Purdy is unable to play, the team may turn to backups Brandon Allen or Joshua Dobbs. The running game, led by Christian McCaffrey, has shown flashes of potential but has been inconsistent, failing to provide the necessary balance to the offense. The receiving corps, featuring George Kittle and Deebo Samuel, has been productive, but injuries have limited their impact. Defensively, the 49ers have been formidable, limiting opponents to an average of 19.5 points per game. However, injuries to key players like Nick Bosa (hip/oblique) could impact their performance. The secondary has been effective in limiting big plays, and the pass rush has been relentless, contributing to the team’s overall defensive success. Special teams have been reliable, with kicker Robbie Gould providing stability and the return units contributing positively to field position. The coaching staff, led by head coach Kyle Shanahan, has faced scrutiny for the team’s performance and decision-making. The focus for the 49ers will be on salvaging the remainder of the season and evaluating talent for the future. This game against the Packers presents an opportunity to break the losing streak and regain some confidence, though the challenges are substantial given the current state of the team.
Credit: USA TODAY/IMAGN
Green Bay Packers NFL Preview
The Green Bay Packers enter this matchup with a 7-3 record, showcasing a balanced and efficient team on both sides of the ball. Quarterback Jordan Love has been a revelation, leading an offense that ranks among the top in the league in both passing and rushing yards per game. The running game, led by Aaron Jones and A.J. Dillon, has provided a solid foundation, allowing the Packers to control the clock and dictate the pace of the game. The receiving corps, featuring Davante Adams and emerging talents like Jayden Reed, has been productive, creating mismatches and stretching opposing defenses. Defensively, the Packers have been opportunistic, creating turnovers and applying consistent pressure on opposing quarterbacks. The secondary, anchored by Jaire Alexander, has been effective in limiting big plays and securing interceptions. The pass rush, led by Rashan Gary and Preston Smith, has been relentless, contributing to the team’s overall defensive success. Special teams have been reliable, with kicker Mason Crosby providing stability and the return units contributing positively to field position. The coaching staff, led by head coach Matt LaFleur, has instilled a winning culture and strategic acumen, contributing to the team’s success. The focus for the Packers will be on maintaining their momentum and securing a playoff berth. This game against the 49ers presents an opportunity to solidify their position in the NFC and continue their upward trajectory.
All righty then.
— Green Bay Packers (@packers) November 20, 2024
📬: @mikespofford
San Francisco vs. Green Bay Prop Picks (AI)
San Francisco vs. Green Bay Prediction (AI)
Remi, our AI sports algorithm, has been pouring over millions of data from every angle between the 49ers and Packers and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most focused on the linear correlation of weight knucklehead sportsbettors tend to put on San Francisco’s strength factors between a 49ers team going up against a possibly tired Packers team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI San Francisco vs Green Bay picks, computer picks 49ers vs Packers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
49ers Betting Trends
The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
Packers Betting Trends
The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
49ers vs. Packers Matchup Trends
Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
San Francisco vs. Green Bay Game Info
What time does San Francisco vs Green Bay start on November 24, 2024?
San Francisco vs Green Bay starts on November 24, 2024 at 5:25 PM EST.
Where is San Francisco vs Green Bay being played?
Venue: Lambeau Field.
What are the opening odds for San Francisco vs Green Bay?
Spread: Green Bay -2.5
Moneyline: San Francisco +118, Green Bay -139
Over/Under: 47.5
What are the records for San Francisco vs Green Bay?
San Francisco: (5-5) Â |Â Green Bay: (7-3)
What is the AI best bet for San Francisco vs Green Bay?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are San Francisco vs Green Bay trending bets?
Historically, when the Packers are home favorites by less than a field goal, they have covered the spread in 70% of such games over the past five seasons. This suggests a potential advantage for Green Bay in this matchup.
What are San Francisco trending bets?
SF trend: The 49ers have struggled against the spread (ATS) recently, failing to cover in their last three games. Their inconsistent performance, particularly on offense, has contributed to this trend.
What are Green Bay trending bets?
GB trend: The Packers have been more reliable ATS, covering in four of their last five games. Their balanced offense and opportunistic defense have played significant roles in meeting betting expectations.
Where can I find AI Picks for San Francisco vs Green Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
San Francisco vs. Green Bay Odds
AI algorithm Remi is pouring through mountains of data points on each player. In fact, anytime the San Francisco vs Green Bay trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.
San Francisco vs Green Bay Opening Odds
SF Moneyline:
+118 GB Moneyline: -139
SF Spread: +2.5
GB Spread: -2.5
Over/Under: 47.5
San Francisco vs Green Bay Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Sep 28, 2025 9:31AM EDT
Minnesota Vikings
Pittsburgh Steelers
9/28/25 9:31AM
Vikings
Steelers
|
–
–
|
-140
+115
|
-2.5 (-115)
+2.5 (-105)
|
O 41 (-110)
U 41 (-110)
|
|
|
Sep 28, 2025 1:00PM EDT
Cleveland Browns
Detroit Lions
9/28/25 1PM
Browns
Lions
|
–
–
|
+400
-550
|
+10 (-110)
-10 (-110)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
|
Sep 28, 2025 1:00PM EDT
Los Angeles Chargers
New York Giants
9/28/25 1PM
Chargers
Giants
|
–
–
|
-285
+230
|
-6.5 (-105)
+6.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Tennessee Titans
Houston Texans
9/28/25 1:01PM
Titans
Texans
|
–
–
|
+300
-375
|
+7 (-105)
-7 (-115)
|
O 39 (-110)
U 39 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Philadelphia Eagles
Tampa Bay Buccaneers
9/28/25 1:01PM
Eagles
Buccaneers
|
–
–
|
-190
+160
|
-3.5 (-105)
+3.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Washington Commanders
Atlanta Falcons
9/28/25 1:01PM
Commanders
Falcons
|
–
–
|
+110
-130
|
+2 (-110)
-2 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
New Orleans Saints
Buffalo Bills
9/28/25 1:01PM
Saints
Bills
|
–
–
|
+800
-1300
|
+15 (-110)
-15 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Carolina Panthers
New England Patriots
9/28/25 1:01PM
Panthers
Patriots
|
–
–
|
+200
-250
|
+5.5 (-110)
-5.5 (-110)
|
O 43 (-110)
U 43 (-110)
|
|
|
Sep 28, 2025 4:06PM EDT
Jacksonville Jaguars
San Francisco 49ers
9/28/25 4:06PM
Jaguars
49ers
|
–
–
|
+150
-180
|
+3.5 (-115)
-3.5 (-105)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Sep 28, 2025 4:06PM EDT
Indianapolis Colts
Los Angeles Rams
9/28/25 4:06PM
Colts
Rams
|
–
–
|
+160
-190
|
+3.5 (-110)
-3.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Sep 28, 2025 4:25PM EDT
Baltimore Ravens
Kansas City Chiefs
9/28/25 4:25PM
Ravens
Chiefs
|
–
–
|
-150
+125
|
-2.5 (-120)
+2.5 (+100)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Sep 28, 2025 4:26PM EDT
Chicago Bears
Las Vegas Raiders
9/28/25 4:26PM
Bears
Raiders
|
–
–
|
+100
-120
|
+1 (-110)
-1 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 8:21PM EDT
Green Bay Packers
Dallas Cowboys
9/28/25 8:21PM
Packers
Cowboys
|
–
–
|
-325
+250
|
-7 (-105)
+7 (-115)
|
O 47 (-110)
U 47 (-110)
|
|
|
Sep 29, 2025 7:15PM EDT
New York Jets
Miami Dolphins
9/29/25 7:15PM
Jets
Dolphins
|
–
–
|
+125
-150
|
+3 (-115)
-3 (-105)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Sep 29, 2025 8:15PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:15PM
Bengals
Broncos
|
–
–
|
+310
-400
|
+7.5 (-110)
-7.5 (-110)
|
O 44 (-110)
U 44 (-110)
|
|
|
Oct 2, 2025 8:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 8:16PM
49ers
Rams
|
–
–
|
+134
-158
|
+3 (-105)
-3 (-115)
|
O 47 (-110)
U 47 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Francisco 49ers vs. Green Bay Packers on November 24, 2024 at Lambeau Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
   LEAN |    %WIN |    UNITS | RESULT |
|---|---|---|---|---|
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |
| GB@CLE | GB -7 | 54.3% | 4 | LOSS |
| ARI@SF | ARI +3 | 57.7% | 6 | WIN |
| KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
| GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
| MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
| LAC@LV | LAC -3 | 54.9% | 4 | WIN |
| TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
| CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
| DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
| PHI@KC | PHI -115 | 56.7% | 6 | WIN |
| SF@NO | SF -3 | 58.8% | 8 | WIN |
| SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
| CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
| DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
| ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
| WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
| WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
| MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
| TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
| SF@SEA | SF -115 | 54.6% | 4 | WIN |
| SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
| CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
| KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
| DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
| KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
| KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
| KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
| KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
| BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
| WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
| BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
| LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
| BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
| HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
| WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
| WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
| MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
| MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
| WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
| WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
| GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
| LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
| LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
| LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |