Chiefs vs Panthers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 24)

Updated: 2024-11-17T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On November 24, 2024, the Kansas City Chiefs (9-1) will visit the Carolina Panthers (3-7) at Bank of America Stadium in Charlotte, North Carolina. The Chiefs aim to rebound from their first loss of the season, while the Panthers seek to build momentum after a recent victory.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 24, 2024

Start Time: 2:00 PM EST​

Venue: Bank of America Stadium​

Panthers Record: (3-7)

Chiefs Record: (9-1)

OPENING ODDS

KC Moneyline: -641

CAR Moneyline: +465

KC Spread: -11

CAR Spread: +11.0

Over/Under: 43

KC
Betting Trends

  • The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.

CAR
Betting Trends

  • The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.

MATCHUP TRENDS

  • The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.

KC vs. CAR
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Kansas City vs Carolina Prediction & Odds:
Free NFL Betting Insights for 11/24/24

The Kansas City Chiefs, boasting a 9-1 record, are set to face the Carolina Panthers (3-7) in a Week 12 matchup at Bank of America Stadium. The Chiefs are coming off their first loss of the season, a 30-21 defeat to the Buffalo Bills, which ended their unbeaten streak. Quarterback Patrick Mahomes, despite the loss, has been performing at an MVP-caliber level, leading an offense that ranks among the league’s best in both passing and scoring. The Chiefs’ defense, while opportunistic, has shown vulnerabilities, particularly against the run. The Panthers, on the other hand, have experienced a challenging season but have shown signs of improvement.

They are coming off back-to-back wins, including a 20-17 overtime victory against the New York Giants in Munich, Germany. Quarterback play has been inconsistent, but the running game, led by a rejuvenated backfield, has been a bright spot. Defensively, the Panthers have struggled to contain high-powered offenses, which could be a concern against the Chiefs’ potent attack. Key factors in this matchup include the Chiefs’ ability to rebound from their first loss and maintain offensive efficiency, and the Panthers’ capacity to control the clock with their running game to keep Mahomes off the field. Special teams could also play a pivotal role, as field position and clutch kicking may influence the game’s outcome.

Kansas City Chiefs NFL Preview

The Kansas City Chiefs, with a 9-1 record, are looking to bounce back after their first loss of the season to the Buffalo Bills. Despite the setback, the Chiefs remain one of the league’s most formidable teams, led by quarterback Patrick Mahomes, who continues to perform at an elite level. Offensively, the Chiefs boast a high-powered attack, ranking among the top in the league in both passing yards and points per game. Mahomes’ connection with his receiving corps, including standout performances from tight end Travis Kelce, has been a cornerstone of their success. The running game, while not the focal point, has been effective in complementing the passing attack, providing balance and keeping defenses honest. Defensively, the Chiefs have been opportunistic, creating turnovers and making key stops in critical situations. However, they have shown some susceptibility against the run, which opponents have tried to exploit. The pass rush, led by a dynamic front seven, has been effective in applying pressure, contributing to the defense’s overall success. Special teams have been a strength for the Chiefs, with reliable kicking and punting units, as well as explosive return capabilities that have provided advantageous field positions. In this matchup, the Chiefs will aim to reestablish their dominance by executing their high-octane offense and tightening up defensive lapses. Limiting turnovers and maintaining discipline, especially in a potentially hostile road environment, will be essential for securing a victory and getting back on track after their recent loss.

On November 24, 2024, the Kansas City Chiefs (9-1) will visit the Carolina Panthers (3-7) at Bank of America Stadium in Charlotte, North Carolina. The Chiefs aim to rebound from their first loss of the season, while the Panthers seek to build momentum after a recent victory. Kansas City vs Carolina AI Prediction: Free NFL Betting Insights for Nov 24. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Carolina Panthers NFL Preview

The Carolina Panthers enter this matchup with a 3-7 record, reflecting a season of ups and downs. After a bye week, they secured a 23-22 victory over the New Orleans Saints and followed it with a 20-17 overtime win against the New York Giants in Munich, Germany. These consecutive wins have provided a morale boost for the team. Offensively, the Panthers have relied heavily on their running game, which has been effective in controlling the clock and setting up play-action opportunities. The quarterback position has seen some instability, but recent performances have shown improvement, with better decision-making and reduced turnovers. The receiving corps, led by a mix of veteran presence and young talent, has been instrumental in moving the chains and providing explosive plays when needed. Defensively, the Panthers have faced challenges, particularly in stopping the run and defending against high-powered passing attacks. However, they have shown resilience in critical moments, with the secondary stepping up to make key plays in recent games. The defensive line has been active in generating pressure, but consistency remains an area for improvement. Special teams have been a mixed bag for the Panthers, with the kicking game showing reliability, but coverage units have allowed some significant returns. Addressing these issues will be crucial against a Chiefs team known for their explosive special teams play. For the Panthers to succeed in this matchup, they will need to execute a balanced offensive game plan, limit turnovers, and find ways to disrupt Mahomes’ rhythm. Controlling time of possession through the running game and capitalizing on scoring opportunities in the red zone will be key factors in their strategy.

Kansas City vs. Carolina Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Chiefs and Panthers play there’s always several intriguing trends to key in on. Not to mention games played at Bank of America Stadium in Nov almost always follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Kansas City vs. Carolina Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Chiefs and Panthers and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the unproportionally assigned factor human bettors regularly put on Carolina’s strength factors between a Chiefs team going up against a possibly healthy Panthers team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Kansas City vs Carolina picks, computer picks Chiefs vs Panthers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 11/10 PHI@GB UNLOCK THIS PICK 6 VAULT v3 Locked VAULT v3
NFL 11/10 PHI@GB UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 11/10 PHI@GB UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 11/10 PHI@GB UNLOCK THIS PICK 1 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Chiefs Betting Trends

The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.

Panthers Betting Trends

The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.

Chiefs vs. Panthers Matchup Trends

The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.

Kansas City vs. Carolina Game Info

Kansas City vs Carolina starts on November 24, 2024 at 2:00 PM EST.

Venue: Bank of America Stadium.

Spread: Carolina +11.0
Moneyline: Kansas City -641, Carolina +465
Over/Under: 43

Kansas City: (9-1)  |  Carolina: (3-7)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.

KC trend: The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.

CAR trend: The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Kansas City vs. Carolina Odds

Remi is pouring through tons of data on each team. In fact, anytime the Kansas City vs Carolina trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.

Kansas City vs Carolina Opening Odds

KC Moneyline: -641
CAR Moneyline: +465
KC Spread: -11
CAR Spread: +11.0
Over/Under: 43

Kansas City vs Carolina Live Odds

Games PTS ML SPR O/U
Nov 10, 2025 8:15PM EST
Philadelphia Eagles
Green Bay Packers
11/10/25 8:15PM
Eagles
Packers
-105
-115
pk
pk
O 45 (-110)
U 45 (-110)
Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
+534
-750
+11.5 (-110)
-11.5 (-110)
O 43 (-110)
U 43 (-110)
Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
+132
-152
+2.5 (+100)
-2.5 (-120)
O 47.5 (-112)
U 47.5 (-108)
Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
+170
-195
+3.5 (-110)
-3.5 (-110)
O 42.5 (-110)
U 42.5 (-110)
Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
+142
-162
+3 (-110)
-3 (-110)
O 48.5 (-115)
U 48.5 (-105)
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
-150
+130
-2.5 (-122)
+2.5 (+102)
O 44 (-110)
U 44 (-110)
Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
-460
+360
-7.5 (-110)
+7.5 (-110)
O 44.5 (-105)
U 44.5 (-115)
Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
+200
-240
+5.5 (-115)
-5.5 (-105)
O 50 (-110)
U 50 (-110)
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
+215
-260
+5.5 (-110)
-5.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
-355
+285
-7 (-113)
+7 (-107)
O 39 (-116)
U 39 (-104)
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
-140
+120
-2.5 (-110)
+2.5 (-110)
O 49 (-110)
U 49 (-110)
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
+130
-150
+2.5 (-101)
-2.5 (-119)
O 49 (-105)
U 49 (-115)
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
-200
+174
-4 (-110)
+4 (-110)
O 44.5 (-110)
U 44.5 (-110)
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
-425
+334
-8.5 (-107)
+8.5 (-113)
O 41.5 (-110)
U 41.5 (-110)
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
+100
-120
+1.5 (-112)
-1.5 (-108)
O 49 (-110)
U 49 (-110)
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
-185
+161
-3.5 (-110)
+3.5 (-110)
O 51 (-104)
U 51 (-116)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Kansas City Chiefs vs. Carolina Panthers on November 24, 2024 at Bank of America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
LV@DEN RILEY MOSS OVER 4.5 TACKLE + ASST 54.8% 4 WIN
LV@DEN UNDER 43 53.4% 2 WIN
ARI@DAL BUDDA BAKER OVER 7.5 TACKLES + ASSTS 54.4% 4 WIN
ARI@DAL GEORGE PICKENS OVER 4.5 RECEPTIONS 56.6% 6 WIN
DEN@HOU WIL LUTZ OVER 1.5 MADE FIELD GOALS 54.2% 3 LOSS
SEA@WAS SEA -3 56.7% 6 WIN
IND@PIT IND -3 56.8% 6 LOSS
LAC@TEN LAC -9.5 56.2% 6 LOSS
CHI@CIN CHI -2.5 52.6% 2 WIN
SEA@WAS OVER 48 52.9% 2 WIN
SEA@WAS JAYDEN DANIELS OVER 20.5 PASS COMP 56.7% 6 LOSS
JAC@LV JAC -140 64.2% 7 WIN
NO@LAR LAR -14 55.0% 4 WIN
DEN@HOU HOU -1.5 54.2% 3 LOSS
CAR@GB GB -12.5 55.4% 5 LOSS
SF@NYG NYG +2.5 56.1% 5 LOSS
BAL@MIA TUA TAGOVAILOA UNDER 0.5 INT 55.3% 5 LOSS
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS
NYG@PHI NYG +7.5 53.9% 3 LOSS
BUF@CAR CAR +7.5 54.2% 3 LOSS
DAL@DEN DAL +3.5 55.0% 4 LOSS
MIA@ATL MIA +7 54.3% 4 WIN
CLE@NE CLE +7 56.8% 6 LOSS
TB@NO BAKER MAYFIELD OVER 15.5 RUSH YDS 56.6% 6 LOSS
MIN@LAC JUSTIN HERBERT PASS ATT UNDER 35.5 55.5% 5 WIN
TB@DET TB +6.5 54.4% 4 LOSS
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS