Chiefs vs Panthers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 24)
Updated: 2024-11-17T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On November 24, 2024, the Kansas City Chiefs (9-1) will visit the Carolina Panthers (3-7) at Bank of America Stadium in Charlotte, North Carolina. The Chiefs aim to rebound from their first loss of the season, while the Panthers seek to build momentum after a recent victory.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Nov 24, 2024
Start Time: 2:00 PM EST
Venue: Bank of America Stadium
Panthers Record: (3-7)
Chiefs Record: (9-1)
OPENING ODDS
KC Moneyline: -641
CAR Moneyline: +465
KC Spread: -11
CAR Spread: +11.0
Over/Under: 43
KC
Betting Trends
- The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.
CAR
Betting Trends
- The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.
MATCHUP TRENDS
- The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.
KC vs. CAR
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Kansas City vs Carolina Prediction & Odds:
Free NFL Betting Insights for 11/24/24
They are coming off back-to-back wins, including a 20-17 overtime victory against the New York Giants in Munich, Germany. Quarterback play has been inconsistent, but the running game, led by a rejuvenated backfield, has been a bright spot. Defensively, the Panthers have struggled to contain high-powered offenses, which could be a concern against the Chiefs’ potent attack. Key factors in this matchup include the Chiefs’ ability to rebound from their first loss and maintain offensive efficiency, and the Panthers’ capacity to control the clock with their running game to keep Mahomes off the field. Special teams could also play a pivotal role, as field position and clutch kicking may influence the game’s outcome.
We went three for three in the red zone in Buffalo 💪 pic.twitter.com/o8qrnIr2sm
— Kansas City Chiefs (@Chiefs) November 20, 2024
Kansas City Chiefs NFL Preview
The Kansas City Chiefs, with a 9-1 record, are looking to bounce back after their first loss of the season to the Buffalo Bills. Despite the setback, the Chiefs remain one of the league’s most formidable teams, led by quarterback Patrick Mahomes, who continues to perform at an elite level. Offensively, the Chiefs boast a high-powered attack, ranking among the top in the league in both passing yards and points per game. Mahomes’ connection with his receiving corps, including standout performances from tight end Travis Kelce, has been a cornerstone of their success. The running game, while not the focal point, has been effective in complementing the passing attack, providing balance and keeping defenses honest. Defensively, the Chiefs have been opportunistic, creating turnovers and making key stops in critical situations. However, they have shown some susceptibility against the run, which opponents have tried to exploit. The pass rush, led by a dynamic front seven, has been effective in applying pressure, contributing to the defense’s overall success. Special teams have been a strength for the Chiefs, with reliable kicking and punting units, as well as explosive return capabilities that have provided advantageous field positions. In this matchup, the Chiefs will aim to reestablish their dominance by executing their high-octane offense and tightening up defensive lapses. Limiting turnovers and maintaining discipline, especially in a potentially hostile road environment, will be essential for securing a victory and getting back on track after their recent loss.

Credit: USA TODAY/IMAGN
Carolina Panthers NFL Preview
The Carolina Panthers enter this matchup with a 3-7 record, reflecting a season of ups and downs. After a bye week, they secured a 23-22 victory over the New Orleans Saints and followed it with a 20-17 overtime win against the New York Giants in Munich, Germany. These consecutive wins have provided a morale boost for the team. Offensively, the Panthers have relied heavily on their running game, which has been effective in controlling the clock and setting up play-action opportunities. The quarterback position has seen some instability, but recent performances have shown improvement, with better decision-making and reduced turnovers. The receiving corps, led by a mix of veteran presence and young talent, has been instrumental in moving the chains and providing explosive plays when needed. Defensively, the Panthers have faced challenges, particularly in stopping the run and defending against high-powered passing attacks. However, they have shown resilience in critical moments, with the secondary stepping up to make key plays in recent games. The defensive line has been active in generating pressure, but consistency remains an area for improvement. Special teams have been a mixed bag for the Panthers, with the kicking game showing reliability, but coverage units have allowed some significant returns. Addressing these issues will be crucial against a Chiefs team known for their explosive special teams play. For the Panthers to succeed in this matchup, they will need to execute a balanced offensive game plan, limit turnovers, and find ways to disrupt Mahomes’ rhythm. Controlling time of possession through the running game and capitalizing on scoring opportunities in the red zone will be key factors in their strategy.
Surprise! A special Germany edition of Blueprint drops tomorrow at 7pm ET.
— Carolina Panthers (@Panthers) November 20, 2024
Subscribe to Panthers YouTube to be notified when the episode debuts. pic.twitter.com/BggXJ2psA3
Kansas City vs. Carolina Prop Picks (AI)
Kansas City vs. Carolina Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Chiefs and Panthers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the unproportionally assigned factor human bettors tend to put on Kansas City’s strength factors between a Chiefs team going up against a possibly improved Panthers team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Kansas City vs Carolina picks, computer picks Chiefs vs Panthers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Chiefs Betting Trends
The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.
Panthers Betting Trends
The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.
Chiefs vs. Panthers Matchup Trends
The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.
Kansas City vs. Carolina Game Info
What time does Kansas City vs Carolina start on November 24, 2024?
Kansas City vs Carolina starts on November 24, 2024 at 2:00 PM EST.
Where is Kansas City vs Carolina being played?
Venue: Bank of America Stadium.
What are the opening odds for Kansas City vs Carolina?
Spread: Carolina +11.0
Moneyline: Kansas City -641, Carolina +465
Over/Under: 43
What are the records for Kansas City vs Carolina?
Kansas City: (9-1) | Carolina: (3-7)
What is the AI best bet for Kansas City vs Carolina?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Kansas City vs Carolina trending bets?
The Chiefs opened as 10.5-point favorites for this matchup. Historically, Kansas City has been favored by double digits in road games but has not consistently covered the spread in such situations.
What are Kansas City trending bets?
KC trend: The Chiefs have struggled against the spread (ATS) recently, failing to cover in their last four games. Despite a strong overall record, their performance relative to betting lines has been inconsistent.
What are Carolina trending bets?
CAR trend: The Panthers have shown resilience, covering the spread in their last two games, both of which were victories. This marks an improvement from earlier in the season when they struggled to meet betting expectations.
Where can I find AI Picks for Kansas City vs Carolina?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Kansas City vs. Carolina Odds
AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Kansas City vs Carolina trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
Kansas City vs Carolina Opening Odds
KC Moneyline:
-641 CAR Moneyline: +465
KC Spread: -11
CAR Spread: +11.0
Over/Under: 43
Kansas City vs Carolina Live Odds
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–
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+148
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O 44.5 (-110)
U 44.5 (-110)
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U 40.5 (-110)
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-463
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O 46 (-110)
U 46 (-110)
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+242
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+7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
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–
–
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+229
-315
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+6.5 (+100)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
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Giants
Eagles
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–
–
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+287
-407
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+7 (-110)
-7 (-110)
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O 43.5 (-110)
U 43.5 (-110)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
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–
–
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-110
-116
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+1 (-110)
-1 (-110)
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O 41.5 (-110)
U 41.5 (-110)
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
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–
–
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+257
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+7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
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–
–
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-220
+169
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-4.5 (-110)
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O 47 (-110)
U 47 (-110)
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Cowboys
Broncos
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–
–
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+141
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+3.5 (-120)
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O 50 (-110)
U 50 (-110)
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Tennessee Titans
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Titans
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–
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+682
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+14 (-110)
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O 47 (-110)
U 47 (-110)
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Packers
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–
–
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-192
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-3.5 (+100)
+3.5 (-120)
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O 44.5 (-110)
U 44.5 (-110)
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Commanders
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–
–
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+390
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+10.5 (-110)
-10.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Kansas City Chiefs vs. Carolina Panthers on November 24, 2024 at Bank of America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |