Seahawks vs 49ers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 17)
Updated: 2024-11-10T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On November 17, 2024, the Seattle Seahawks (4-5) will face the San Francisco 49ers (5-4) at Levi’s Stadium in Santa Clara, California. This NFC West matchup is crucial for both teams as they vie for playoff positioning in a tightly contested division.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Nov 17, 2024
Start Time: 5:05 PM EST
Venue: Levi's Stadium
49ers Record: (5-4)
Seahawks Record: (4-5)
OPENING ODDS
SEA Moneyline: +252
SF Moneyline: -319
SEA Spread: +6.5
SF Spread: -6.5
Over/Under: 49.5
SEA
Betting Trends
- The Seahawks have struggled against the spread (ATS) this season, covering in only 2 of their last 8 games, reflecting challenges in meeting betting expectations.
SF
Betting Trends
- The 49ers hold a balanced ATS record, covering in about half of their games this season.
MATCHUP TRENDS
- Historically, the 49ers have had mixed results covering the spread against the Seahawks, indicating Seattle’s competitive edge in this rivalry.
SEA vs. SF
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Seattle vs San Francisco Prediction & Odds:
Free NFL Betting Insights for 11/17/24
Quarterback Brock Purdy has been efficient, throwing for over 2,000 yards and 18 touchdowns with a low interception rate. His rapport with wide receivers Deebo Samuel and Brandon Aiyuk has been a highlight, with both receivers contributing significantly to the passing game. The running game, featuring Jordan Mason in the absence of Christian McCaffrey, has been productive, with Mason rushing for 536 yards. The 49ers’ offense averages 26 points per game, reflecting a balanced and potent attack. Defensively, San Francisco has been formidable, allowing an average of 20 points per game. Linebacker Fred Warner anchors the defense with 90 tackles and 5 sacks, providing leadership and playmaking ability. The secondary, led by cornerback Charvarius Ward, has been effective in pass coverage, contributing to the team’s 12 interceptions. The defense excels in creating pressure, recording 25 sacks this season, which has disrupted opposing quarterbacks and limited big-play opportunities. Special teams could play a pivotal role in this matchup. Seahawks kicker Jason Myers has been reliable, converting 88% of his field goal attempts, while 49ers kicker Jake Moody has maintained an 85% conversion rate. Field position and the kicking game may influence the outcome in what is expected to be a closely contested battle. In summary, this game features two teams with contrasting strengths. The Seahawks will aim to exploit the 49ers’ run defense, while San Francisco seeks to capitalize on Seattle’s defensive vulnerabilities. Turnovers and third-down efficiency are likely to be key factors in determining the winner of this contest.
The numbers behind JSN's 180-yard day. 📊@NextGenStats | @awscloud pic.twitter.com/FSmKHSubZ1
— Seattle Seahawks (@Seahawks) November 11, 2024
Seattle Seahawks NFL Preview
The San Francisco 49ers have had a season filled with ups and downs, holding a 5-4 record as they aim to find consistency. Quarterback Brock Purdy has shown strong command, throwing for over 2,000 yards and 18 touchdowns while maintaining a low interception rate. His connection with Deebo Samuel and Brandon Aiyuk has been effective, with both wideouts combining for over 1,200 receiving yards and 10 touchdowns. The ground game, currently led by Jordan Mason, has provided stability in Christian McCaffrey’s absence, as Mason has rushed for 536 yards. The offensive line has performed well, offering solid protection and helping the 49ers maintain an average of 26 points per game. Defensively, the 49ers are led by the dynamic play of linebacker Fred Warner, who has recorded 90 tackles and 5 sacks. Cornerback Charvarius Ward has anchored the secondary with consistent coverage, helping the defense achieve 12 interceptions this season. The 49ers’ defense allows an average of 20 points per game and has excelled in pressuring quarterbacks, with a total of 25 sacks. Despite overall strength, San Francisco has occasionally struggled to contain the run, allowing 115 rushing yards per game Special teams for the 49ers have been reliable, with kicker Jake Moody converting 85% of his field goal attempts and punter Mitch Wishnowsky helping control field position with an average of 46 yards per punt. The return game has shown promise, though big plays have been limited, keeping the starting field position steady. Under head coach Kyle Shanahan, the 49ers emphasize a balanced offensive approach and an aggressive, disciplined defense. Offensive coordinator Bobby Slowik has crafted effective schemes to leverage Purdy’s efficiency and the skill positions, while defensive coordinator Steve Wilks has instilled a tough, opportunistic mindset on defense. For San Francisco, continuing to limit turnovers and enhancing run defense will be key in sustaining their momentum and competing for a division title. Looking forward, the 49ers are focused on improving consistency and maintaining momentum. Key areas include bolstering run defense and building on the chemistry between Purdy and his primary targets. With tough games ahead, the 49ers aim to solidify their playoff position and make a strong push in the latter part of the season.

Credit: USA TODAY/IMAGN
San Francisco 49ers NFL Preview
The Seattle Seahawks have experienced a season of highs and lows, currently holding a 4-5 record. Offensively, quarterback Geno Smith has been instrumental, throwing for over 2,200 yards and 15 touchdowns. His rapport with wide receivers DK Metcalf and Tyler Lockett remains strong, with both players combining for over 1,200 receiving yards and 10 touchdowns. The addition of rookie wideout Jaxon Smith-Njigba has provided an additional target, contributing 400 receiving yards and 3 touchdowns. The running game, led by Kenneth Walker III, has added balance, with Walker rushing for 800 yards and 7 touchdowns. The offensive line has faced challenges, allowing 22 sacks, which has occasionally disrupted the offensive rhythm. Defensively, the Seahawks have been anchored by linebacker Jordyn Brooks, who has recorded 85 tackles and consistently disrupted opposing offenses. Linebacker Uchenna Nwosu leads the team with 6 sacks, showcasing his ability to pressure quarterbacks. The secondary, featuring cornerback Tariq Woolen, has been effective, with the team recording 10 interceptions. However, the defense has shown vulnerability against the run, allowing 130 rushing yards per game, indicating an area for improvement. Special teams have been a consistent asset for the Seahawks. Kicker Jason Myers has been reliable, converting 88% of his field goal attempts, including several from beyond 50 yards. Punter Michael Dickson has been effective in flipping field position, averaging 46 yards per punt. The return game, led by DeeJay Dallas, has provided solid field position, contributing to the offense’s success. The coaching staff, under head coach Pete Carroll, has emphasized a balanced offensive attack and aggressive defensive schemes. Offensive coordinator Shane Waldron has implemented creative play designs that maximize the talents of Smith and the receiving corps. Defensive coordinator Clint Hurtt has focused on leveraging the strengths of key players like Brooks and Nwosu to create pressure and force turnovers. Looking ahead, the Seahawks aim to address their inconsistencies and make a push for the playoffs. Maintaining offensive balance and improving run defense will be crucial as they face formidable opponents in the latter part of the season.
Back at our place.
— San Francisco 49ers (@49ers) November 12, 2024
🎟️: https://t.co/lBSo1qg2kX pic.twitter.com/b5pADoXhGK
Seattle vs. San Francisco Prop Picks (AI)
Seattle vs. San Francisco Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every past game between the Seahawks and 49ers and using recursive machine learning and impressive AI to boil down the data to a single cover probability.
The Algorithm has been most focused on the linear correlation of factor knucklehead sportsbettors often put on player performance factors between a Seahawks team going up against a possibly improved 49ers team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Seattle vs San Francisco picks, computer picks Seahawks vs 49ers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Seahawks Betting Trends
The Seahawks have struggled against the spread (ATS) this season, covering in only 2 of their last 8 games, reflecting challenges in meeting betting expectations.
49ers Betting Trends
The 49ers hold a balanced ATS record, covering in about half of their games this season.
Seahawks vs. 49ers Matchup Trends
Historically, the 49ers have had mixed results covering the spread against the Seahawks, indicating Seattle’s competitive edge in this rivalry.
Seattle vs. San Francisco Game Info
What time does Seattle vs San Francisco start on November 17, 2024?
Seattle vs San Francisco starts on November 17, 2024 at 5:05 PM EST.
Where is Seattle vs San Francisco being played?
Venue: Levi's Stadium.
What are the opening odds for Seattle vs San Francisco?
Spread: San Francisco -6.5
Moneyline: Seattle +252, San Francisco -319
Over/Under: 49.5
What are the records for Seattle vs San Francisco?
Seattle: (4-5) | San Francisco: (5-4)
What is the AI best bet for Seattle vs San Francisco?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Seattle vs San Francisco trending bets?
Historically, the 49ers have had mixed results covering the spread against the Seahawks, indicating Seattle’s competitive edge in this rivalry.
What are Seattle trending bets?
SEA trend: The Seahawks have struggled against the spread (ATS) this season, covering in only 2 of their last 8 games, reflecting challenges in meeting betting expectations.
What are San Francisco trending bets?
SF trend: The 49ers hold a balanced ATS record, covering in about half of their games this season.
Where can I find AI Picks for Seattle vs San Francisco?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Seattle vs. San Francisco Odds
Remi is pouring through mountains of data on each line. In fact, anytime the Seattle vs San Francisco trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps can often follow normal, predictable betting trends.
Seattle vs San Francisco Opening Odds
SEA Moneyline:
+252 SF Moneyline: -319
SEA Spread: +6.5
SF Spread: -6.5
Over/Under: 49.5
Seattle vs San Francisco Live Odds
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–
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+146
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+3 (-102)
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O 44.5 (-112)
U 44.5 (-108)
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Cleveland Browns
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–
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+290
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+7 (-114)
-7 (-106)
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O 40.5 (-105)
U 40.5 (-115)
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Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
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Panthers
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–
–
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-370
+295
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-7.5 (-102)
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O 46.5 (-105)
U 46.5 (-115)
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–
–
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+245
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+6.5 (-110)
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O 43.5 (-115)
U 43.5 (-105)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
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–
–
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+265
-330
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+6.5 (-106)
-6.5 (-114)
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O 50.5 (-105)
U 50.5 (-115)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
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+285
-355
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+7 (-108)
-7 (-112)
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O 43.5 (-105)
U 43.5 (-115)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-102
-118
|
+1.5 (-115)
-1.5 (-105)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
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+280
-350
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+7.5 (-122)
-7.5 (+100)
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O 44.5 (-114)
U 44.5 (-106)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-225
+188
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-4.5 (-106)
+4.5 (-114)
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O 46.5 (-114)
U 46.5 (-106)
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Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
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–
–
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+146
-174
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+3.5 (-118)
-3.5 (-104)
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O 49.5 (-120)
U 49.5 (-102)
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
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–
–
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+750
-1200
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+14.5 (-118)
-14.5 (-104)
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O 46.5 (-114)
U 46.5 (-106)
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Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
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–
–
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-176
+148
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-3.5 (-104)
+3.5 (-118)
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O 44.5 (-115)
U 44.5 (-105)
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
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–
–
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+430
-590
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+10.5 (-110)
-10.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Seattle Seahawks vs. San Francisco 49ers on November 17, 2024 at Levi's Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |