49ers vs Buccaneers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Nov 10)
Updated: 2024-11-03T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Francisco 49ers (4-4) will face the Tampa Bay Buccaneers (4-4) on November 10, 2024, at Raymond James Stadium in Tampa, Florida. Both teams are seeking to improve their records and strengthen their positions in their respective divisions.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 10, 2024
Start Time: 2:00 PM EST
Venue: Raymond James Stadium
Buccaneers Record: (4-5)
49ers Record: (4-4)
OPENING ODDS
SF Moneyline: -278
TB Moneyline: +227
SF Spread: -6.5
TB Spread: +6.5
Over/Under: 48.5
SF
Betting Trends
- The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
TB
Betting Trends
- The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
MATCHUP TRENDS
- In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
SF vs. TB
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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San Francisco vs Tampa Bay Prediction & Odds:
Free NFL Betting Insights for 11/10/24
Conversely, the Buccaneers are grappling with a two-game losing streak and have been plagued by injuries, notably to key receivers Mike Evans and Chris Godwin. Quarterback Baker Mayfield has been inconsistent, and the team’s defense has allowed over 30 points per game in recent outings. The Buccaneers’ struggles in both offensive production and defensive resilience have contributed to their current challenges. This game is crucial for both teams as they vie for playoff contention. The 49ers’ balanced attack and defensive prowess position them as favorites, while the Buccaneers must address their vulnerabilities to secure a home victory.
Welcomed back a few guys after the bye.
— San Francisco 49ers (@49ers) November 5, 2024
Christian McCaffrey, Jauan Jennings and more return to practice ⬇️
San Francisco 49ers NFL Preview
The San Francisco 49ers, holding a 4-4 record, are looking to build momentum in the second half of the season. Quarterback Brock Purdy has been effective, completing 156 of 242 passes for 2,101 yards, 10 touchdowns, and 7 interceptions. Tight end George Kittle has been a reliable target, recording 40 receptions for 503 yards and 6 touchdowns. The potential return of running back Christian McCaffrey, who has been on injured reserve, could provide a significant boost to the running game. Defensively, the 49ers have been strong, with linebacker Fred Warner leading the team with multiple interceptions and forced fumbles. The secondary has been solid, with cornerback Deommodore Lenoir excelling in coverage. The defensive line, however, has faced challenges in consistently pressuring opposing quarterbacks. Special teams have been reliable, with kicker Jake Moody converting key field goals and the return units providing favorable field positions. Head coach Kyle Shanahan emphasizes discipline and execution as the team prepares for the Buccaneers. The 49ers aim to capitalize on the Buccaneers’ recent struggles and leverage their balanced attack to secure a road victory.
Credit: USA TODAY/IMAGN
Tampa Bay Buccaneers NFL Preview
The Tampa Bay Buccaneers enter Week 10 with a 4-4 record, facing challenges on both sides of the ball. Offensively, quarterback Baker Mayfield has thrown for over 2,100 yards and 21 touchdowns but has also committed 9 interceptions, reflecting inconsistency. The absence of top receivers Mike Evans and Chris Godwin due to injuries has further hampered the passing game. Running back Brian Irving has been a bright spot, rushing for 395 yards and 3 touchdowns, but the overall offensive output has been insufficient. Defensively, the Buccaneers have struggled, allowing an average of over 30 points per game in their last five contests. The secondary has been particularly vulnerable, giving up significant yardage through the air. Linebacker Lavonte David continues to be a leader on defense, but the unit as a whole has been unable to contain opposing offenses effectively. Special teams have been inconsistent, with missed field goals and subpar return coverage contributing to unfavorable field positions. Head coach Todd Bowles faces the challenge of addressing these issues to prevent the season from slipping further. Hosting the 49ers, the Buccaneers must improve their defensive performance and find ways to compensate for the injuries on offense to secure a win.
"We're not going to get used to losing. We had some big plays, we took our swings, but they connected more than we did. We fought but it wasn't good enough, so we've got to get ready for another one next week."
— Tampa Bay Buccaneers (@Buccaneers) November 5, 2024
-HC Todd Bowles
San Francisco vs. Tampa Bay Prop Picks (AI)
San Francisco vs. Tampa Bay Prediction (AI)
Remi, our AI sports algorithm, has been pouring over mountains of data from every simulation between the 49ers and Buccaneers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
The Algorithm has been most watching on the linear correlation of weight knucklehead sportsbettors tend to put on San Francisco’s strength factors between a 49ers team going up against a possibly rested Buccaneers team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI San Francisco vs Tampa Bay picks, computer picks 49ers vs Buccaneers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
EXECUTIVE
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
INTEL
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
INTEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
49ers Betting Trends
The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
Buccaneers Betting Trends
The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
49ers vs. Buccaneers Matchup Trends
In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
San Francisco vs. Tampa Bay Game Info
What time does San Francisco vs Tampa Bay start on November 10, 2024?
San Francisco vs Tampa Bay starts on November 10, 2024 at 2:00 PM EST.
Where is San Francisco vs Tampa Bay being played?
Venue: Raymond James Stadium.
What are the opening odds for San Francisco vs Tampa Bay?
Spread: Tampa Bay +6.5
Moneyline: San Francisco -278, Tampa Bay +227
Over/Under: 48.5
What are the records for San Francisco vs Tampa Bay?
San Francisco: (4-4) | Tampa Bay: (4-5)
What is the AI best bet for San Francisco vs Tampa Bay?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are San Francisco vs Tampa Bay trending bets?
In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
What are San Francisco trending bets?
SF trend: The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
What are Tampa Bay trending bets?
TB trend: The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
Where can I find AI Picks for San Francisco vs Tampa Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
San Francisco vs. Tampa Bay Odds
AI algorithm Remi is pouring through tons of data on each line. In fact, anytime the San Francisco vs Tampa Bay trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.
San Francisco vs Tampa Bay Opening Odds
SF Moneyline:
-278 TB Moneyline: +227
SF Spread: -6.5
TB Spread: +6.5
Over/Under: 48.5
San Francisco vs Tampa Bay Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
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Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
|
–
–
|
+148
-185
|
+3 (+100)
-3 (-120)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
|
–
–
|
+270
-374
|
+7 (-110)
-7 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-463
+321
|
-7.5 (-110)
+7.5 (-110)
|
O 46 (-110)
U 46 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
|
+242
-330
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+229
-315
|
+6.5 (+100)
-6.5 (-120)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+287
-407
|
+7 (-110)
-7 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-110
-116
|
+1 (-110)
-1 (-110)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+257
-355
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-220
+169
|
-4.5 (-110)
+4.5 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+141
-181
|
+3.5 (-120)
-3.5 (+100)
|
O 50 (-110)
U 50 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+682
-1442
|
+14 (-110)
-14 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-192
+148
|
-3.5 (+100)
+3.5 (-120)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+390
-599
|
+10.5 (-110)
-10.5 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Francisco 49ers vs. Tampa Bay Buccaneers on November 10, 2024 at Raymond James Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |