49ers vs. Buccaneers
Prediction, Odds & Props
Nov 10 | NFL AI Picks
Updated: 2024-11-03T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Francisco 49ers (4-4) will face the Tampa Bay Buccaneers (4-4) on November 10, 2024, at Raymond James Stadium in Tampa, Florida. Both teams are seeking to improve their records and strengthen their positions in their respective divisions.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 10, 2024
Start Time: 2:00 PM EST​
Venue: Raymond James Stadium​
Buccaneers Record: (4-5)
49ers Record: (4-4)
OPENING ODDS
SF Moneyline: -278
TB Moneyline: +227
SF Spread: -6.5
TB Spread: +6.5
Over/Under: 48.5
SF
Betting Trends
- The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
TB
Betting Trends
- The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
MATCHUP TRENDS
- In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
SF vs. TB
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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San Francisco vs Tampa Bay Prediction & Odds:
Free NFL Betting Insights for 11/10/24
Conversely, the Buccaneers are grappling with a two-game losing streak and have been plagued by injuries, notably to key receivers Mike Evans and Chris Godwin. Quarterback Baker Mayfield has been inconsistent, and the team’s defense has allowed over 30 points per game in recent outings. The Buccaneers’ struggles in both offensive production and defensive resilience have contributed to their current challenges. This game is crucial for both teams as they vie for playoff contention. The 49ers’ balanced attack and defensive prowess position them as favorites, while the Buccaneers must address their vulnerabilities to secure a home victory.
Welcomed back a few guys after the bye.
— San Francisco 49ers (@49ers) November 5, 2024
Christian McCaffrey, Jauan Jennings and more return to practice ⬇️
San Francisco 49ers NFL Preview
The San Francisco 49ers, holding a 4-4 record, are looking to build momentum in the second half of the season. Quarterback Brock Purdy has been effective, completing 156 of 242 passes for 2,101 yards, 10 touchdowns, and 7 interceptions. Tight end George Kittle has been a reliable target, recording 40 receptions for 503 yards and 6 touchdowns. The potential return of running back Christian McCaffrey, who has been on injured reserve, could provide a significant boost to the running game. Defensively, the 49ers have been strong, with linebacker Fred Warner leading the team with multiple interceptions and forced fumbles. The secondary has been solid, with cornerback Deommodore Lenoir excelling in coverage. The defensive line, however, has faced challenges in consistently pressuring opposing quarterbacks. Special teams have been reliable, with kicker Jake Moody converting key field goals and the return units providing favorable field positions. Head coach Kyle Shanahan emphasizes discipline and execution as the team prepares for the Buccaneers. The 49ers aim to capitalize on the Buccaneers’ recent struggles and leverage their balanced attack to secure a road victory.
Credit: USA TODAY/IMAGN
Tampa Bay Buccaneers NFL Preview
The Tampa Bay Buccaneers enter Week 10 with a 4-4 record, facing challenges on both sides of the ball. Offensively, quarterback Baker Mayfield has thrown for over 2,100 yards and 21 touchdowns but has also committed 9 interceptions, reflecting inconsistency. The absence of top receivers Mike Evans and Chris Godwin due to injuries has further hampered the passing game. Running back Brian Irving has been a bright spot, rushing for 395 yards and 3 touchdowns, but the overall offensive output has been insufficient. Defensively, the Buccaneers have struggled, allowing an average of over 30 points per game in their last five contests. The secondary has been particularly vulnerable, giving up significant yardage through the air. Linebacker Lavonte David continues to be a leader on defense, but the unit as a whole has been unable to contain opposing offenses effectively. Special teams have been inconsistent, with missed field goals and subpar return coverage contributing to unfavorable field positions. Head coach Todd Bowles faces the challenge of addressing these issues to prevent the season from slipping further. Hosting the 49ers, the Buccaneers must improve their defensive performance and find ways to compensate for the injuries on offense to secure a win.
"We're not going to get used to losing. We had some big plays, we took our swings, but they connected more than we did. We fought but it wasn't good enough, so we've got to get ready for another one next week."
— Tampa Bay Buccaneers (@Buccaneers) November 5, 2024
-HC Todd Bowles
San Francisco vs. Tampa Bay Prop Picks (AI)
San Francisco vs. Tampa Bay Prediction (AI)
Remi, our AI sports algorithm, has been pouring over tons of data from every past game between the 49ers and Buccaneers and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most keyed in on the trending emphasis emotional bettors often put on player performance factors between a 49ers team going up against a possibly healthy Buccaneers team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI San Francisco vs Tampa Bay picks, computer picks 49ers vs Buccaneers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
49ers Betting Trends
The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
Buccaneers Betting Trends
The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
49ers vs. Buccaneers Matchup Trends
In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
San Francisco vs. Tampa Bay Game Info
What time does San Francisco vs Tampa Bay start on November 10, 2024?
San Francisco vs Tampa Bay starts on November 10, 2024 at 2:00 PM EST.
Where is San Francisco vs Tampa Bay being played?
Venue: Raymond James Stadium.
What are the opening odds for San Francisco vs Tampa Bay?
Spread: Tampa Bay +6.5
Moneyline: San Francisco -278, Tampa Bay +227
Over/Under: 48.5
What are the records for San Francisco vs Tampa Bay?
San Francisco: (4-4) Â |Â Tampa Bay: (4-5)
What is the AI best bet for San Francisco vs Tampa Bay?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are San Francisco vs Tampa Bay trending bets?
In their last five head-to-head matchups, the 49ers have covered the spread four times against the Buccaneers, suggesting a favorable trend for San Francisco in this series.
What are San Francisco trending bets?
SF trend: The 49ers have covered the spread in 5 of their last 8 games this season, indicating a 62.5% success rate against the spread (ATS).
What are Tampa Bay trending bets?
TB trend: The Buccaneers have covered the spread in 3 of their last 8 games this season, reflecting a 37.5% ATS success rate.
Where can I find AI Picks for San Francisco vs Tampa Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
San Francisco vs. Tampa Bay Odds
AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the San Francisco vs Tampa Bay trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable patterns.
San Francisco vs Tampa Bay Opening Odds
SF Moneyline:
-278 TB Moneyline: +227
SF Spread: -6.5
TB Spread: +6.5
Over/Under: 48.5
San Francisco vs Tampa Bay Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Sep 28, 2025 9:31AM EDT
Minnesota Vikings
Pittsburgh Steelers
9/28/25 9:31AM
Vikings
Steelers
|
–
–
|
-140
+115
|
-2.5 (-115)
+2.5 (-105)
|
O 41 (-110)
U 41 (-110)
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|
|
Sep 28, 2025 1:00PM EDT
Cleveland Browns
Detroit Lions
9/28/25 1PM
Browns
Lions
|
–
–
|
+400
-550
|
+10 (-110)
-10 (-110)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
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Sep 28, 2025 1:00PM EDT
Los Angeles Chargers
New York Giants
9/28/25 1PM
Chargers
Giants
|
–
–
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-285
+230
|
-6.5 (-105)
+6.5 (-115)
|
O 44 (-110)
U 44 (-110)
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|
Sep 28, 2025 1:01PM EDT
Tennessee Titans
Houston Texans
9/28/25 1:01PM
Titans
Texans
|
–
–
|
+300
-375
|
+7 (-105)
-7 (-115)
|
O 39 (-110)
U 39 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Philadelphia Eagles
Tampa Bay Buccaneers
9/28/25 1:01PM
Eagles
Buccaneers
|
–
–
|
-190
+160
|
-3.5 (-105)
+3.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
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Sep 28, 2025 1:01PM EDT
Washington Commanders
Atlanta Falcons
9/28/25 1:01PM
Commanders
Falcons
|
–
–
|
+110
-130
|
+2 (-110)
-2 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
New Orleans Saints
Buffalo Bills
9/28/25 1:01PM
Saints
Bills
|
–
–
|
+800
-1300
|
+15 (-110)
-15 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Carolina Panthers
New England Patriots
9/28/25 1:01PM
Panthers
Patriots
|
–
–
|
+200
-250
|
+5.5 (-110)
-5.5 (-110)
|
O 43 (-110)
U 43 (-110)
|
|
|
Sep 28, 2025 4:06PM EDT
Jacksonville Jaguars
San Francisco 49ers
9/28/25 4:06PM
Jaguars
49ers
|
–
–
|
+150
-180
|
+3.5 (-115)
-3.5 (-105)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Sep 28, 2025 4:06PM EDT
Indianapolis Colts
Los Angeles Rams
9/28/25 4:06PM
Colts
Rams
|
–
–
|
+160
-190
|
+3.5 (-110)
-3.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Sep 28, 2025 4:25PM EDT
Baltimore Ravens
Kansas City Chiefs
9/28/25 4:25PM
Ravens
Chiefs
|
–
–
|
-150
+125
|
-2.5 (-120)
+2.5 (+100)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Sep 28, 2025 4:26PM EDT
Chicago Bears
Las Vegas Raiders
9/28/25 4:26PM
Bears
Raiders
|
–
–
|
+100
-120
|
+1 (-110)
-1 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 8:21PM EDT
Green Bay Packers
Dallas Cowboys
9/28/25 8:21PM
Packers
Cowboys
|
–
–
|
-325
+250
|
-7 (-105)
+7 (-115)
|
O 47 (-110)
U 47 (-110)
|
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|
Sep 29, 2025 7:15PM EDT
New York Jets
Miami Dolphins
9/29/25 7:15PM
Jets
Dolphins
|
–
–
|
+125
-150
|
+3 (-115)
-3 (-105)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Sep 29, 2025 8:15PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:15PM
Bengals
Broncos
|
–
–
|
+310
-400
|
+7.5 (-110)
-7.5 (-110)
|
O 44 (-110)
U 44 (-110)
|
|
|
Oct 2, 2025 8:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 8:16PM
49ers
Rams
|
–
–
|
+134
-158
|
+3 (-105)
-3 (-115)
|
O 47 (-110)
U 47 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Francisco 49ers vs. Tampa Bay Buccaneers on November 10, 2024 at Raymond James Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
   LEAN |    %WIN |    UNITS | RESULT |
|---|---|---|---|---|
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |
| GB@CLE | GB -7 | 54.3% | 4 | LOSS |
| ARI@SF | ARI +3 | 57.7% | 6 | WIN |
| KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
| GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
| MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
| LAC@LV | LAC -3 | 54.9% | 4 | WIN |
| TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
| CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
| DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
| PHI@KC | PHI -115 | 56.7% | 6 | WIN |
| SF@NO | SF -3 | 58.8% | 8 | WIN |
| SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
| CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
| DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
| ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
| WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
| WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
| MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
| TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
| SF@SEA | SF -115 | 54.6% | 4 | WIN |
| SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
| CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
| KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
| DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
| KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
| KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
| KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
| KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
| BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
| WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
| BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
| LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
| BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
| HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
| WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
| WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
| MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
| MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
| WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
| WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
| GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
| LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
| LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
| LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |