Colts vs Texans Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 27)
Updated: 2024-10-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indianapolis Colts (4-3) will face the Houston Texans (5-2) on October 27, 2024, at NRG Stadium in a crucial AFC South divisional matchup. Both teams are fighting for playoff positioning, with Houston favored to win by 5.5 points, but Indianapolis is looking to pull off an upset.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 27, 2024
Start Time: 1:00 PM EST
Venue: NRG Stadium
Texans Record: (5-2)
Colts Record: (4-3)
OPENING ODDS
IND Moneyline: +217
HOU Moneyline: -267
IND Spread: +6
HOU Spread: -6.0
Over/Under: 46
IND
Betting Trends
- The Colts are 3-2-1 ATS in their last six games, performing well on the road in particular. They have also been strong against divisional opponents this season.
HOU
Betting Trends
- The Texans have covered the spread in four of their last five games, showing resilience at home. Houston is 3-1 ATS at NRG Stadium in 2024, consistently beating the spread when playing as favorites.
MATCHUP TRENDS
- The Colts have covered the spread in eight of their last 12 matchups against the Texans, including several road games. However, Houston has been dominant as of late, covering in their last two home games against AFC South rivals.
IND vs. HOU
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Indianapolis vs Houston Prediction & Odds:
Free NFL Betting Insights for 10/27/24
The Colts, at 4-3, have been up-and-down this season, primarily due to the inconsistency of rookie quarterback Anthony Richardson. Richardson, known for his athleticism, has had flashes of brilliance but has also struggled with turnovers. Indianapolis will lean heavily on running back Jonathan Taylor, who has returned to form after a slow start, and wide receivers Michael Pittman Jr. and Josh Downs to create offensive production. The key to this game will be whether the Colts’ defense, led by Shaquille Leonard and DeForest Buckner, can disrupt Stroud’s rhythm and limit big plays. Both teams are likely to rely on their running games to control the clock, but the Texans’ ability to spread the field with their dynamic passing attack may give them the edge in this contest.
Ready when called. pic.twitter.com/t5849ezzJY
— Indianapolis Colts (@Colts) October 21, 2024
Indianapolis Colts NFL Preview
The Indianapolis Colts enter this matchup with a 4-3 record, battling for consistency in a competitive AFC South. Rookie quarterback Anthony Richardson has been the centerpiece of the Colts’ offense, using both his arm and legs to make plays. However, Richardson has struggled with turnovers, throwing six interceptions on the season, which has stalled drives and led to missed opportunities. The Colts will need a cleaner performance from him to pull off an upset in Houston. Running back Jonathan Taylor has been the focal point of the offense since returning from injury, and his ability to grind out tough yards will be key against a Texans defense that ranks in the middle of the pack against the run. Taylor has rushed for over 100 yards in back-to-back games, and his ability to control the pace of the game will be vital for Indianapolis. Defensively, the Colts have been inconsistent, allowing 25 points per game. The pass rush, led by DeForest Buckner, has been strong at times, but the secondary has been prone to giving up big plays. Indianapolis will need to tighten up its coverage against a Texans offense that loves to spread the ball around. If the Colts can limit the explosive plays from C.J. Stroud and force him into difficult situations, they’ll have a chance to keep this game within reach. This game represents a major opportunity for the Colts to stay in the playoff hunt, but they’ll need a complete performance on both sides of the ball to upset the Texans.

Credit: USA TODAY/IMAGN
Houston Texans NFL Preview
The Houston Texans are one of the NFL’s surprise teams this season, coming into Week 8 with a 5-2 record. A big reason for their success has been the play of rookie quarterback C.J. Stroud, who has thrown for over 1,800 yards and 12 touchdowns through the first seven games. Stroud has formed a strong connection with his top receivers, Stefon Diggs and Tank Dell, making the Texans’ passing game one of the most efficient in the league. On the ground, Joe Mixon has added another dimension to Houston’s offense, averaging 4.5 yards per carry and consistently finding the end zone. Defensively, the Texans have been opportunistic, ranking in the top 10 in takeaways this season. Led by a young, talented core that includes edge rusher Will Anderson Jr. and safety Jalen Pitre, Houston’s defense has been able to apply pressure on opposing quarterbacks while maintaining solid coverage in the secondary. At home, the Texans have been particularly tough, allowing fewer than 20 points per game at NRG Stadium. Looking ahead to their matchup against the Colts, the Texans will aim to capitalize on Indianapolis’s shaky offensive line and force Anthony Richardson into uncomfortable passing situations. If Houston’s front seven can contain Jonathan Taylor and limit the Colts’ running game, they’ll be in a strong position to take control of the game early and keep their division lead.
Joe doing Joe things 🤫 pic.twitter.com/m9cX8LwIAT
— Houston Texans (@HoustonTexans) October 21, 2024
Indianapolis vs. Houston Prop Picks (AI)
Indianapolis vs. Houston Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every angle between the Colts and Texans and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the unproportionally assigned factor knucklehead sportsbettors often put on coaching factors between a Colts team going up against a possibly healthy Texans team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Indianapolis vs Houston picks, computer picks Colts vs Texans, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Colts Betting Trends
The Colts are 3-2-1 ATS in their last six games, performing well on the road in particular. They have also been strong against divisional opponents this season.
Texans Betting Trends
The Texans have covered the spread in four of their last five games, showing resilience at home. Houston is 3-1 ATS at NRG Stadium in 2024, consistently beating the spread when playing as favorites.
Colts vs. Texans Matchup Trends
The Colts have covered the spread in eight of their last 12 matchups against the Texans, including several road games. However, Houston has been dominant as of late, covering in their last two home games against AFC South rivals.
Indianapolis vs. Houston Game Info
What time does Indianapolis vs Houston start on October 27, 2024?
Indianapolis vs Houston starts on October 27, 2024 at 1:00 PM EST.
Where is Indianapolis vs Houston being played?
Venue: NRG Stadium.
What are the opening odds for Indianapolis vs Houston?
Spread: Houston -6.0
Moneyline: Indianapolis +217, Houston -267
Over/Under: 46
What are the records for Indianapolis vs Houston?
Indianapolis: (4-3) | Houston: (5-2)
What is the AI best bet for Indianapolis vs Houston?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Indianapolis vs Houston trending bets?
The Colts have covered the spread in eight of their last 12 matchups against the Texans, including several road games. However, Houston has been dominant as of late, covering in their last two home games against AFC South rivals.
What are Indianapolis trending bets?
IND trend: The Colts are 3-2-1 ATS in their last six games, performing well on the road in particular. They have also been strong against divisional opponents this season.
What are Houston trending bets?
HOU trend: The Texans have covered the spread in four of their last five games, showing resilience at home. Houston is 3-1 ATS at NRG Stadium in 2024, consistently beating the spread when playing as favorites.
Where can I find AI Picks for Indianapolis vs Houston?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Indianapolis vs. Houston Odds
Remi is pouring through mountains of stats on each line. In fact, anytime the Indianapolis vs Houston trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.
Indianapolis vs Houston Opening Odds
IND Moneyline:
+217 HOU Moneyline: -267
IND Spread: +6
HOU Spread: -6.0
Over/Under: 46
Indianapolis vs Houston Live Odds
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–
–
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+148
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O 44.5 (-110)
U 44.5 (-110)
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U 40.5 (-110)
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–
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-463
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O 46 (-110)
U 46 (-110)
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–
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+242
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
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10/26/25 1PM
Bears
Ravens
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–
–
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+229
-315
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+6.5 (+100)
-6.5 (-120)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
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Giants
Eagles
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–
–
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+287
-407
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+7 (-110)
-7 (-110)
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O 43.5 (-110)
U 43.5 (-110)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
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–
–
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-110
-116
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+1 (-110)
-1 (-110)
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O 41.5 (-110)
U 41.5 (-110)
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
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–
–
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+257
-355
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+7 (-110)
-7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
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–
–
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-220
+169
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-4.5 (-110)
+4.5 (-110)
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O 47 (-110)
U 47 (-110)
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Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
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–
–
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+141
-181
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+3.5 (-120)
-3.5 (+100)
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O 50 (-110)
U 50 (-110)
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
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10/26/25 4:25PM
Titans
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|
–
–
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+682
-1442
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+14 (-110)
-14 (-110)
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O 47 (-110)
U 47 (-110)
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Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
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–
–
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-192
+148
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-3.5 (+100)
+3.5 (-120)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
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Commanders
Chiefs
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–
–
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+390
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+10.5 (-110)
-10.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indianapolis Colts vs. Houston Texans on October 27, 2024 at NRG Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |