Titans vs Bills Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 20)

Updated: 2024-10-13T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Tennessee Titans travel to face the Buffalo Bills on October 20, 2024, at Highmark Stadium in Orchard Park. The Bills, currently 4-2, are heavy favorites against the struggling Titans, who sit at 1-4.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 20, 2024

Start Time: 1:00 PM EST​

Venue: Highmark Stadium​

Bills Record:

Titans Record:

OPENING ODDS

TEN Moneyline: +349

BUF Moneyline: -452

TEN Spread: +9

BUF Spread: -9.0

Over/Under: 41.5

TEN
Betting Trends

  • The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.

BUF
Betting Trends

  • The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.

MATCHUP TRENDS

  • The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.

TEN vs. BUF
Best Prop Bet

  • Remi searched hard and found the best prop bet prediction for this matchup: T. Pollard RB OVER 63.5 rushing yards

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Tennessee vs Buffalo Prediction & Odds:
Free NFL Betting Insights for 10/20/24

The Buffalo Bills will host the Tennessee Titans in a Week 7 matchup on October 20, 2024, in what appears to be a significant mismatch on paper. The Bills, sitting at 4-2 and atop the AFC East, have been one of the most consistent teams in the league this season, led by MVP candidate Josh Allen. In contrast, the Titans have struggled to a 1-4 record and find themselves near the bottom of the AFC South standings. Josh Allen, who has already passed for over 1,160 yards and 10 touchdowns without an interception, will look to exploit a Titans defense that has been vulnerable through the air. Tennessee has allowed an average of 137 passing yards per game, but their rushing defense has been slightly more effective, giving up 111.8 rushing yards per game. The Bills, however, can counter with running back James Cook, who has added over 300 rushing yards this season, providing balance to Buffalo’s offense. On the other side, Tennessee’s offensive struggles have been glaring. Rookie quarterback Will Levis has thrown seven interceptions to just five touchdowns, contributing to the team’s lack of consistent offensive production. The Titans’ offense has only managed an average of 19.2 points per game, which is a major concern as they go up against one of the league’s top defenses. The Bills have been limiting opponents to just 21 points per game and have an aggressive pass rush, spearheaded by Von Miller. While Tennessee does have some offensive weapons, including wide receiver DeAndre Hopkins and running back Tony Pollard, they’ll need a near-perfect performance to keep up with the Bills. If Buffalo’s defense can pressure Levis into mistakes, it could be a long afternoon for the Titans.

Tennessee Titans NFL Preview

The Tennessee Titans face an uphill battle against the Bills in Week 7. Currently sitting at 1-4, the Titans have struggled to find consistency, particularly on offense. Rookie quarterback Will Levis has shown flashes of potential but has also made costly mistakes, throwing seven interceptions through five games. If Tennessee is going to have any chance of pulling off an upset, Levis will need to limit turnovers and make smart decisions against a fierce Bills defense. The Titans’ running game, led by Tony Pollard, has been one of the few bright spots. Pollard has rushed for over 300 yards this season and will need to have a big game to help control the clock and keep Josh Allen off the field. DeAndre Hopkins, Tennessee’s top receiver, has struggled to find his footing, and the Titans will need a more consistent performance from him if they hope to compete against Buffalo’s secondary. Defensively, Tennessee has had mixed results. Their run defense has been solid, giving up only 111.8 rushing yards per game, but their pass defense will be tested against Allen and the Bills’ dynamic offense. The Titans have managed to keep games close, limiting opponents to 22 points per game, but their inability to generate consistent offense has left them in tough positions late in games. To stay competitive against the Bills, Tennessee will need a near-perfect defensive performance and must capitalize on any turnovers they can force.

The Tennessee Titans travel to face the Buffalo Bills on October 20, 2024, at Highmark Stadium in Orchard Park. The Bills, currently 4-2, are heavy favorites against the struggling Titans, who sit at 1-4. Tennessee vs Buffalo AI Prediction: Free NFL Betting Insights for Oct 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Buffalo Bills NFL Preview

The Buffalo Bills come into this Week 7 contest against the Tennessee Titans riding high on a 4-2 record, looking to solidify their position at the top of the AFC East. Head coach Sean McDermott has crafted one of the most well-rounded teams in the league, led by quarterback Josh Allen. Allen has been spectacular this season, throwing for over 1,160 yards and 10 touchdowns while remaining interception-free, which has been crucial to the team’s success. Buffalo’s offense is explosive, averaging over 27.5 points per game. James Cook, the team’s leading rusher, has been an effective complement to Allen, providing balance to the offense with over 300 rushing yards. On the receiving end, Khalil Shakir has stepped up, leading the Bills with 249 receiving yards. With the combination of Allen’s arm and Cook’s running ability, Buffalo’s offense is capable of scoring in bunches. Defensively, Buffalo has been just as strong, holding opponents to 21 points per game and excelling at creating pressure. The return of Von Miller has bolstered their pass rush, and linebacker Dorian Williams has been a tackling machine, leading the team with 59 tackles. If Buffalo can get after Titans quarterback Will Levis and force turnovers, they should have no problem controlling the game.

Tennessee vs. Buffalo Prop Picks (AI)

Remi is pouring through tons of stats on each team. In fact, anytime the Titans and Bills play there’s always several intriguing trends to key in on. Not to mention games played at Highmark Stadium in Oct seemingly never follow normal, predictable patterns.
Remi searched hard and found the best prop bet prediction for this matchup: T. Pollard RB OVER 63.5 rushing yards

Tennessee vs. Buffalo Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every facet between the Titans and Bills and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.

Remi has been most keyed in on the unproportionally assigned factor emotional bettors regularly put on coaching factors between a Titans team going up against a possibly deflated Bills team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Tennessee vs Buffalo picks, computer picks Titans vs Bills, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 5 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Titans Betting Trends

The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.

Bills Betting Trends

The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.

Titans vs. Bills Matchup Trends

The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.

Tennessee vs. Buffalo Game Info

Tennessee vs Buffalo starts on October 20, 2024 at 1:00 PM EST.

Spread: Buffalo -9.0
Moneyline: Tennessee +349, Buffalo -452
Over/Under: 41.5

Remi searched hard and found the best prop bet prediction for this matchup: T. Pollard RB OVER 63.5 rushing yards. Prices move—always shop for the best number.

The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.

TEN trend: The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.

BUF trend: The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Tennessee vs. Buffalo Odds

AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Tennessee vs Buffalo trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps rarely follow normal, predictable patterns.

Tennessee vs Buffalo Opening Odds

TEN Moneyline: +349
BUF Moneyline: -452
TEN Spread: +9
BUF Spread: -9.0
Over/Under: 41.5

Tennessee vs Buffalo Live Odds

Games PTS ML SPR O/U
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
+146
-174
+3 (-102)
-3 (-120)
O 44.5 (-112)
U 44.5 (-108)
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
+290
-360
+7 (-114)
-7 (-106)
O 40.5 (-105)
U 40.5 (-115)
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
-370
+295
-7.5 (-102)
+7.5 (-120)
O 46.5 (-105)
U 46.5 (-115)
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
+245
-300
+6.5 (-110)
-6.5 (-110)
O 43.5 (-115)
U 43.5 (-105)
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
+265
-330
+6.5 (-106)
-6.5 (-114)
O 50.5 (-105)
U 50.5 (-115)
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
+285
-355
+7 (-108)
-7 (-112)
O 43.5 (-105)
U 43.5 (-115)
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
-102
-118
+1.5 (-115)
-1.5 (-105)
O 41.5 (-110)
U 41.5 (-110)
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
+280
-350
+7.5 (-122)
-7.5 (+100)
O 44.5 (-114)
U 44.5 (-106)
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
-225
+188
-4.5 (-106)
+4.5 (-114)
O 46.5 (-114)
U 46.5 (-106)
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
+146
-174
+3.5 (-118)
-3.5 (-104)
O 49.5 (-120)
U 49.5 (-102)
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
+750
-1200
+14.5 (-118)
-14.5 (-104)
O 46.5 (-114)
U 46.5 (-106)
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
-176
+148
-3.5 (-104)
+3.5 (-118)
O 44.5 (-115)
U 44.5 (-105)
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
+430
-590
+10.5 (-110)
-10.5 (-110)
O 47.5 (-110)
U 47.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Tennessee Titans vs. Buffalo Bills on October 20, 2024 at Highmark Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS