Titans vs Bills Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 20)
Updated: 2024-10-13T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Tennessee Titans travel to face the Buffalo Bills on October 20, 2024, at Highmark Stadium in Orchard Park. The Bills, currently 4-2, are heavy favorites against the struggling Titans, who sit at 1-4.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 20, 2024
Start Time: 1:00 PM EST
Venue: Highmark Stadium
Bills Record:
Titans Record:
OPENING ODDS
TEN Moneyline: +349
BUF Moneyline: -452
TEN Spread: +9
BUF Spread: -9.0
Over/Under: 41.5
TEN
Betting Trends
- The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.
BUF
Betting Trends
- The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.
MATCHUP TRENDS
- The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.
TEN vs. BUF
Best Prop Bet
- Remi searched hard and found the best prop bet prediction for this matchup: T. Pollard RB OVER 63.5 rushing yards
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Tennessee vs Buffalo Prediction & Odds:
Free NFL Betting Insights for 10/20/24
Find yourself in the crowd! Check out the Titans FanCam to share your Titans FanCam moment presented by @ascenstthomas
— Tennessee Titans (@Titans) October 15, 2024
🏟️ » https://t.co/v8idz2tf2u pic.twitter.com/x6ISTO3tN1
Tennessee Titans NFL Preview
The Tennessee Titans face an uphill battle against the Bills in Week 7. Currently sitting at 1-4, the Titans have struggled to find consistency, particularly on offense. Rookie quarterback Will Levis has shown flashes of potential but has also made costly mistakes, throwing seven interceptions through five games. If Tennessee is going to have any chance of pulling off an upset, Levis will need to limit turnovers and make smart decisions against a fierce Bills defense. The Titans’ running game, led by Tony Pollard, has been one of the few bright spots. Pollard has rushed for over 300 yards this season and will need to have a big game to help control the clock and keep Josh Allen off the field. DeAndre Hopkins, Tennessee’s top receiver, has struggled to find his footing, and the Titans will need a more consistent performance from him if they hope to compete against Buffalo’s secondary. Defensively, Tennessee has had mixed results. Their run defense has been solid, giving up only 111.8 rushing yards per game, but their pass defense will be tested against Allen and the Bills’ dynamic offense. The Titans have managed to keep games close, limiting opponents to 22 points per game, but their inability to generate consistent offense has left them in tough positions late in games. To stay competitive against the Bills, Tennessee will need a near-perfect defensive performance and must capitalize on any turnovers they can force.

Credit: USA TODAY/IMAGN
Buffalo Bills NFL Preview
The Buffalo Bills come into this Week 7 contest against the Tennessee Titans riding high on a 4-2 record, looking to solidify their position at the top of the AFC East. Head coach Sean McDermott has crafted one of the most well-rounded teams in the league, led by quarterback Josh Allen. Allen has been spectacular this season, throwing for over 1,160 yards and 10 touchdowns while remaining interception-free, which has been crucial to the team’s success. Buffalo’s offense is explosive, averaging over 27.5 points per game. James Cook, the team’s leading rusher, has been an effective complement to Allen, providing balance to the offense with over 300 rushing yards. On the receiving end, Khalil Shakir has stepped up, leading the Bills with 249 receiving yards. With the combination of Allen’s arm and Cook’s running ability, Buffalo’s offense is capable of scoring in bunches. Defensively, Buffalo has been just as strong, holding opponents to 21 points per game and excelling at creating pressure. The return of Von Miller has bolstered their pass rush, and linebacker Dorian Williams has been a tackling machine, leading the team with 59 tackles. If Buffalo can get after Titans quarterback Will Levis and force turnovers, they should have no problem controlling the game.
QB1.#GoBills | #BillsMafia pic.twitter.com/4SSOpTgg9u
— Buffalo Bills (@BuffaloBills) October 17, 2024
Tennessee vs. Buffalo Prop Picks (AI)
Tennessee vs. Buffalo Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Titans and Bills and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most keyed in on the unproportionally assigned factor emotional bettors regularly put on coaching factors between a Titans team going up against a possibly deflated Bills team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Tennessee vs Buffalo picks, computer picks Titans vs Bills, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Titans Betting Trends
The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.
Bills Betting Trends
The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.
Titans vs. Bills Matchup Trends
The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.
Tennessee vs. Buffalo Game Info
What time does Tennessee vs Buffalo start on October 20, 2024?
Tennessee vs Buffalo starts on October 20, 2024 at 1:00 PM EST.
Where is Tennessee vs Buffalo being played?
Venue: Highmark Stadium.
What are the opening odds for Tennessee vs Buffalo?
Spread: Buffalo -9.0
Moneyline: Tennessee +349, Buffalo -452
Over/Under: 41.5
What are the records for Tennessee vs Buffalo?
Tennessee: | Buffalo:
What is the AI best bet for Tennessee vs Buffalo?
Remi searched hard and found the best prop bet prediction for this matchup: T. Pollard RB OVER 63.5 rushing yards. Prices move—always shop for the best number.
What are Tennessee vs Buffalo trending bets?
The over/under is set at 41 points. While Buffalo’s high-powered offense has exceeded 41 points in three of their last five games, Tennessee’s inconsistent scoring makes this total unpredictable.
What are Tennessee trending bets?
TEN trend: The Titans have not performed well against the spread (ATS) recently, covering only twice in their last five games. They’ve particularly struggled in road games, showing inconsistent offensive performances.
What are Buffalo trending bets?
BUF trend: The Bills, favored by 9 points, have been strong ATS, covering in four of their last six games, especially at home, where they’ve capitalized on their high-powered offense and solid defense.
Where can I find AI Picks for Tennessee vs Buffalo?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Tennessee vs. Buffalo Odds
AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Tennessee vs Buffalo trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps rarely follow normal, predictable patterns.
Tennessee vs Buffalo Opening Odds
TEN Moneyline:
+349 BUF Moneyline: -452
TEN Spread: +9
BUF Spread: -9.0
Over/Under: 41.5
Tennessee vs Buffalo Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
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–
–
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+146
-174
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+3 (-102)
-3 (-120)
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O 44.5 (-112)
U 44.5 (-108)
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Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
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–
–
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+290
-360
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+7 (-114)
-7 (-106)
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O 40.5 (-105)
U 40.5 (-115)
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Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-370
+295
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-7.5 (-102)
+7.5 (-120)
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O 46.5 (-105)
U 46.5 (-115)
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Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
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+245
-300
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+6.5 (-110)
-6.5 (-110)
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O 43.5 (-115)
U 43.5 (-105)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+265
-330
|
+6.5 (-106)
-6.5 (-114)
|
O 50.5 (-105)
U 50.5 (-115)
|
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+285
-355
|
+7 (-108)
-7 (-112)
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O 43.5 (-105)
U 43.5 (-115)
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-102
-118
|
+1.5 (-115)
-1.5 (-105)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+280
-350
|
+7.5 (-122)
-7.5 (+100)
|
O 44.5 (-114)
U 44.5 (-106)
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|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-225
+188
|
-4.5 (-106)
+4.5 (-114)
|
O 46.5 (-114)
U 46.5 (-106)
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Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+146
-174
|
+3.5 (-118)
-3.5 (-104)
|
O 49.5 (-120)
U 49.5 (-102)
|
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
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+750
-1200
|
+14.5 (-118)
-14.5 (-104)
|
O 46.5 (-114)
U 46.5 (-106)
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-176
+148
|
-3.5 (-104)
+3.5 (-118)
|
O 44.5 (-115)
U 44.5 (-105)
|
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
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+430
-590
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+10.5 (-110)
-10.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Tennessee Titans vs. Buffalo Bills on October 20, 2024 at Highmark Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |