The Kansas City Chiefs and San Francisco 49ers are set to clash in a marquee Week 7 matchup on October 20, 2024. The game, taking place at Levi’s Stadium, pits the unbeaten Chiefs (5-0) against the 3-3 49ers in what could be a potential playoff preview. Both teams come into the game with potent offenses and defenses capable of making game-changing plays, setting up a thrilling contest.

The Chiefs, led by quarterback Patrick Mahomes, have looked dominant through the first five weeks. Mahomes has passed for 1,235 yards and 6 touchdowns, continuing to show why he’s one of the NFL’s elite. His connection with tight end Travis Kelce remains crucial, though the team’s offense has been balanced by the emergence of running back Kareem Hunt, who has added over 170 rushing yards. Kansas City’s offense ranks 11th in total yards but will face a stiff challenge against a strong 49ers defense. San Francisco’s offense, orchestrated by Brock Purdy, has been one of the league’s most productive, averaging 429.5 yards per game. Purdy has passed for over 1,600 yards, with 9 touchdowns through six games. The 49ers’ ground game, led by Jordan Mason, who has racked up 609 rushing yards, has kept opposing defenses on their heels. Wide receiver Brandon Aiyuk has been Purdy’s primary target, with 351 receiving yards on the season. On defense, the Chiefs have been solid, allowing just 17 points per game, good for 6th in the league. Their ability to shut down opposing offenses, especially in the red zone, will be crucial as they look to contain San Francisco’s rushing attack. The 49ers, on the other hand, are strong against both the run and the pass, ranking in the top 10 in total defense. This matchup is expected to be closely contested, with both teams needing to execute on both sides of the ball to come out on top. The 49ers’ balanced attack and home-field advantage give them a slight edge, but the Chiefs, with Mahomes leading the way, are always a threat to pull off a victory.