Colts vs Jaguars Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 06)
Updated: 2024-09-29T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indianapolis Colts (2-2) will travel to face the Jacksonville Jaguars (0-4) on October 6, 2024, at EverBank Stadium in Jacksonville, Florida. The Colts are coming off a tight 27-24 win over the Pittsburgh Steelers, while the Jaguars are still seeking their first victory of the season after a close 24-20 loss to the Houston Texans.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Oct 06, 2024
Start Time: 1:00 PM EST
Venue: EverBank Stadium
Jaguars Record: (0-4)
Colts Record: (2-2)
OPENING ODDS
IND Moneyline: +125
JAC Moneyline: -148
IND Spread: +2.5
JAC Spread: -2.5
Over/Under: 46
IND
Betting Trends
- The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
JAC
Betting Trends
- The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
MATCHUP TRENDS
- The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
IND vs. JAC
Best Prop Bet
- Remi's searched hard and found a NFL AI prop bet for this matchup: Trevor Lawrence Under 234.5 Passing Yards
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Indianapolis vs Jacksonville Prediction & Odds:
Free NFL Betting Insights for 10/6/24
Trevor Lawrence has struggled to find consistency, and the Jacksonville offense has been hampered by turnovers and a lack of third-down efficiency. The Jaguars’ defense, allowing 380 yards per game, has been one of the league’s worst, particularly against the pass. The key matchup will be whether Jacksonville’s defense can slow down the Colts’ run game, which averages 131.8 yards per game. If Taylor gets going early, it could be a long day for the Jaguars. Jacksonville needs to find a way to put points on the board early to keep the game close and put pressure on Indianapolis’ offense to respond. Expect a physical, divisional battle, with both teams looking to gain an edge in the AFC South standings.
EJ’s everywhere. 👀
— Indianapolis Colts (@Colts) October 1, 2024
📺 #INDvsJAX | 10/6 on CBS pic.twitter.com/Zs5cOuUZuZ
Indianapolis Colts NFL Preview
The Jacksonville Jaguars enter this game desperate for a win. At 0-4, they have shown flashes of potential but have been unable to close out games, with multiple losses by a single score. Trevor Lawrence has been under pressure, completing just 59.2% of his passes, while the ground game, led by Travis Etienne, has failed to consistently produce. The offense averages just 4.9 yards per play, ranking 28th in the league, and has converted only 25% of third downs, the worst mark in the NFL. Defensively, Jacksonville’s issues have been equally glaring. They rank 30th in points allowed (27.3 per game) and are particularly vulnerable against the pass, giving up 272.8 passing yards per game, the second-most in the league. Their red zone defense has been poor, allowing opponents to convert 75% of their trips inside the 20-yard line into touchdowns. To win, the Jaguars must clean up their third-down efficiency on both sides of the ball and force turnovers to keep Indianapolis’ offense off the field.
Credit: USA TODAY/IMAGN
Jacksonville Jaguars NFL Preview
The Indianapolis Colts have bounced back after a slow start to the season and are now sitting at 2-2. Rookie quarterback Anthony Richardson has been efficient, showing flashes of his dual-threat capabilities. He has formed a solid partnership with star running back Jonathan Taylor, who has powered the Colts’ ground attack, averaging 5.0 yards per carry. Indianapolis has been effective in the red zone, converting 61.5% of their trips into touchdowns. Defensively, the Colts have been solid against the run, giving up just 107.3 rushing yards per game, but have shown some vulnerability against the pass, allowing 272.8 yards through the air. The key for Indianapolis will be to pressure Trevor Lawrence and force the Jaguars into long third-down situations, where Jacksonville has struggled all season. The Colts will look to establish the run early and control the clock, preventing the Jaguars from finding any offensive rhythm. Overall, this game represents a chance for the Colts to break their long-standing losing streak in Jacksonville, but the Jaguars will be motivated to get their first win of the season. The outcome will likely hinge on whether Jacksonville’s defense can finally step up and contain a balanced Colts’ offense.
Step on the field with 5! 🗣️#DUUUVAL
— Jacksonville Jaguars (@Jaguars) October 2, 2024
Indianapolis vs. Jacksonville Prop Picks (AI)
Indianapolis vs. Jacksonville Prediction (AI)
Remi, our AI sports algorithm, has been pouring over millions of data from every facet between the Colts and Jaguars and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the growing factor human bettors regularly put on player performance factors between a Colts team going up against a possibly rested Jaguars team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Indianapolis vs Jacksonville picks, computer picks Colts vs Jaguars, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 6 |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 4 |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 4 |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 1 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Colts Betting Trends
The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
Jaguars Betting Trends
The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
Colts vs. Jaguars Matchup Trends
The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
Indianapolis vs. Jacksonville Game Info
What time does Indianapolis vs Jacksonville start on October 06, 2024?
Indianapolis vs Jacksonville starts on October 06, 2024 at 1:00 PM EST.
Where is Indianapolis vs Jacksonville being played?
Venue: EverBank Stadium.
What are the opening odds for Indianapolis vs Jacksonville?
Spread: Jacksonville -2.5
Moneyline: Indianapolis +125, Jacksonville -148
Over/Under: 46
What are the records for Indianapolis vs Jacksonville?
Indianapolis: (2-2) | Jacksonville: (0-4)
What is the AI best bet for Indianapolis vs Jacksonville?
Remi's searched hard and found a NFL AI prop bet for this matchup: Trevor Lawrence Under 234.5 Passing Yards. Prices move—always shop for the best number.
What are Indianapolis vs Jacksonville trending bets?
The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
What are Indianapolis trending bets?
IND trend: The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
What are Jacksonville trending bets?
JAC trend: The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
Where can I find AI Picks for Indianapolis vs Jacksonville?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Indianapolis vs. Jacksonville Odds
Remi is pouring through mountains of stats on each player. In fact, anytime the Indianapolis vs Jacksonville trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.
Indianapolis vs Jacksonville Opening Odds
IND Moneyline:
+125 JAC Moneyline: -148
IND Spread: +2.5
JAC Spread: -2.5
Over/Under: 46
Indianapolis vs Jacksonville Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
|
–
–
|
+500
-835
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+12 (-114)
-12 (-110)
|
O 43.5 (-113)
U 43.5 (-113)
|
|
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Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
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–
–
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+112
-148
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+2.5 (-109)
-2.5 (-117)
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O 47 (-117)
U 47 (-109)
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|
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Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
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–
–
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+160
-205
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+3.5 (-112)
-3.5 (-114)
|
O 42.5 (-112)
U 42.5 (-114)
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|
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Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
|
–
–
|
+120
-159
|
+3 (-115)
-3 (-109)
|
O 48 (-109)
U 48 (-117)
|
|
|
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
|
–
–
|
-150
+118
|
-2.5 (-120)
+2.5 (-106)
|
O 44 (-112)
U 44 (-114)
|
|
|
Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
|
–
–
|
-450
+350
|
-7.5 (-114)
+7.5 (-106)
|
O 44.5 (-105)
U 44.5 (-115)
|
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Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
|
–
–
|
+205
-265
|
+5.5 (-115)
-5.5 (-110)
|
O 49.5 (-114)
U 49.5 (-112)
|
|
|
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
|
–
–
|
+200
-250
|
+5.5 (-114)
-5.5 (-112)
|
O 49 (-112)
U 49 (-114)
|
|
|
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
|
–
–
|
-400
+295
|
-7 (-117)
+7 (-109)
|
O 39.5 (-109)
U 39.5 (-115)
|
|
|
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
|
–
–
|
-159
+118
|
-3 (-108)
+3 (-118)
|
O 48.5 (-112)
U 48.5 (-113)
|
|
|
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
|
–
–
|
+123
-155
|
+2.5 (-109)
-2.5 (-117)
|
O 48 (-113)
U 48 (-113)
|
|
|
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
|
–
–
|
-210
+160
|
-4 (-112)
+4 (-114)
|
O 44.5 (-110)
U 44.5 (-115)
|
|
|
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
|
–
–
|
-500
+350
|
-8.5 (-112)
+8.5 (-114)
|
O 41.5 (-112)
U 41.5 (-113)
|
|
|
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
|
–
–
|
+106
-124
|
+1.5 (-110)
-1.5 (-110)
|
O 48.5 (-105)
U 48.5 (-115)
|
|
|
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
|
–
–
|
-186
+145
|
-3.5 (-107)
+3.5 (-120)
|
O 50.5 (-112)
U 50.5 (-114)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indianapolis Colts vs. Jacksonville Jaguars on October 06, 2024 at EverBank Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| LV@DEN | RILEY MOSS OVER 4.5 TACKLE + ASST | 54.8% | 4 | WIN |
| LV@DEN | UNDER 43 | 53.4% | 2 | WIN |
| ARI@DAL | BUDDA BAKER OVER 7.5 TACKLES + ASSTS | 54.4% | 4 | WIN |
| ARI@DAL | GEORGE PICKENS OVER 4.5 RECEPTIONS | 56.6% | 6 | WIN |
| DEN@HOU | WIL LUTZ OVER 1.5 MADE FIELD GOALS | 54.2% | 3 | LOSS |
| SEA@WAS | SEA -3 | 56.7% | 6 | WIN |
| IND@PIT | IND -3 | 56.8% | 6 | LOSS |
| LAC@TEN | LAC -9.5 | 56.2% | 6 | LOSS |
| CHI@CIN | CHI -2.5 | 52.6% | 2 | WIN |
| SEA@WAS | OVER 48 | 52.9% | 2 | WIN |
| SEA@WAS | JAYDEN DANIELS OVER 20.5 PASS COMP | 56.7% | 6 | LOSS |
| JAC@LV | JAC -140 | 64.2% | 7 | WIN |
| NO@LAR | LAR -14 | 55.0% | 4 | WIN |
| DEN@HOU | HOU -1.5 | 54.2% | 3 | LOSS |
| CAR@GB | GB -12.5 | 55.4% | 5 | LOSS |
| SF@NYG | NYG +2.5 | 56.1% | 5 | LOSS |
| BAL@MIA | TUA TAGOVAILOA UNDER 0.5 INT | 55.3% | 5 | LOSS |
| TB@NO | TB -3.5 | 52.3% | 1 | WIN |
| GB@PIT | GB -2.5 | 52.3% | 1 | WIN |
| SF@HOU | SF +2.5 | 56.0% | 6 | LOSS |
| NYG@PHI | NYG +7.5 | 53.9% | 3 | LOSS |
| BUF@CAR | CAR +7.5 | 54.2% | 3 | LOSS |
| DAL@DEN | DAL +3.5 | 55.0% | 4 | LOSS |
| MIA@ATL | MIA +7 | 54.3% | 4 | WIN |
| CLE@NE | CLE +7 | 56.8% | 6 | LOSS |
| TB@NO | BAKER MAYFIELD OVER 15.5 RUSH YDS | 56.6% | 6 | LOSS |
| MIN@LAC | JUSTIN HERBERT PASS ATT UNDER 35.5 | 55.5% | 5 | WIN |
| TB@DET | TB +6.5 | 54.4% | 4 | LOSS |
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |