Colts vs Jaguars Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 06)
Updated: 2024-09-29T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indianapolis Colts (2-2) will travel to face the Jacksonville Jaguars (0-4) on October 6, 2024, at EverBank Stadium in Jacksonville, Florida. The Colts are coming off a tight 27-24 win over the Pittsburgh Steelers, while the Jaguars are still seeking their first victory of the season after a close 24-20 loss to the Houston Texans.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Oct 06, 2024
Start Time: 1:00 PM EST
Venue: EverBank Stadium
Jaguars Record: (0-4)
Colts Record: (2-2)
OPENING ODDS
IND Moneyline: +125
JAC Moneyline: -148
IND Spread: +2.5
JAC Spread: -2.5
Over/Under: 46
IND
Betting Trends
- The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
JAC
Betting Trends
- The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
MATCHUP TRENDS
- The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
IND vs. JAC
Best Prop Bet
- Remi's searched hard and found a NFL AI prop bet for this matchup: Trevor Lawrence Under 234.5 Passing Yards
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Indianapolis vs Jacksonville Prediction & Odds:
Free NFL Betting Insights for 10/6/24
Trevor Lawrence has struggled to find consistency, and the Jacksonville offense has been hampered by turnovers and a lack of third-down efficiency. The Jaguars’ defense, allowing 380 yards per game, has been one of the league’s worst, particularly against the pass. The key matchup will be whether Jacksonville’s defense can slow down the Colts’ run game, which averages 131.8 yards per game. If Taylor gets going early, it could be a long day for the Jaguars. Jacksonville needs to find a way to put points on the board early to keep the game close and put pressure on Indianapolis’ offense to respond. Expect a physical, divisional battle, with both teams looking to gain an edge in the AFC South standings.
EJ’s everywhere. 👀
— Indianapolis Colts (@Colts) October 1, 2024
📺 #INDvsJAX | 10/6 on CBS pic.twitter.com/Zs5cOuUZuZ
Indianapolis Colts NFL Preview
The Jacksonville Jaguars enter this game desperate for a win. At 0-4, they have shown flashes of potential but have been unable to close out games, with multiple losses by a single score. Trevor Lawrence has been under pressure, completing just 59.2% of his passes, while the ground game, led by Travis Etienne, has failed to consistently produce. The offense averages just 4.9 yards per play, ranking 28th in the league, and has converted only 25% of third downs, the worst mark in the NFL. Defensively, Jacksonville’s issues have been equally glaring. They rank 30th in points allowed (27.3 per game) and are particularly vulnerable against the pass, giving up 272.8 passing yards per game, the second-most in the league. Their red zone defense has been poor, allowing opponents to convert 75% of their trips inside the 20-yard line into touchdowns. To win, the Jaguars must clean up their third-down efficiency on both sides of the ball and force turnovers to keep Indianapolis’ offense off the field.
Credit: USA TODAY/IMAGN
Jacksonville Jaguars NFL Preview
The Indianapolis Colts have bounced back after a slow start to the season and are now sitting at 2-2. Rookie quarterback Anthony Richardson has been efficient, showing flashes of his dual-threat capabilities. He has formed a solid partnership with star running back Jonathan Taylor, who has powered the Colts’ ground attack, averaging 5.0 yards per carry. Indianapolis has been effective in the red zone, converting 61.5% of their trips into touchdowns. Defensively, the Colts have been solid against the run, giving up just 107.3 rushing yards per game, but have shown some vulnerability against the pass, allowing 272.8 yards through the air. The key for Indianapolis will be to pressure Trevor Lawrence and force the Jaguars into long third-down situations, where Jacksonville has struggled all season. The Colts will look to establish the run early and control the clock, preventing the Jaguars from finding any offensive rhythm. Overall, this game represents a chance for the Colts to break their long-standing losing streak in Jacksonville, but the Jaguars will be motivated to get their first win of the season. The outcome will likely hinge on whether Jacksonville’s defense can finally step up and contain a balanced Colts’ offense.
Step on the field with 5! 🗣️#DUUUVAL
— Jacksonville Jaguars (@Jaguars) October 2, 2024
Indianapolis vs. Jacksonville Prop Picks (AI)
Indianapolis vs. Jacksonville Prediction (AI)
Remi, our AI sports wizard, has been pouring over mountains of data from every angle between the Colts and Jaguars and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
The Algorithm has been most watching on the unproportionally assigned factor knucklehead sportsbettors tend to put on Indianapolis’s strength factors between a Colts team going up against a possibly improved Jaguars team. In reality, the true game analytics might reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Indianapolis vs Jacksonville picks, computer picks Colts vs Jaguars, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Colts Betting Trends
The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
Jaguars Betting Trends
The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
Colts vs. Jaguars Matchup Trends
The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
Indianapolis vs. Jacksonville Game Info
What time does Indianapolis vs Jacksonville start on October 06, 2024?
Indianapolis vs Jacksonville starts on October 06, 2024 at 1:00 PM EST.
Where is Indianapolis vs Jacksonville being played?
Venue: EverBank Stadium.
What are the opening odds for Indianapolis vs Jacksonville?
Spread: Jacksonville -2.5
Moneyline: Indianapolis +125, Jacksonville -148
Over/Under: 46
What are the records for Indianapolis vs Jacksonville?
Indianapolis: (2-2) | Jacksonville: (0-4)
What is the AI best bet for Indianapolis vs Jacksonville?
Remi's searched hard and found a NFL AI prop bet for this matchup: Trevor Lawrence Under 234.5 Passing Yards. Prices move—always shop for the best number.
What are Indianapolis vs Jacksonville trending bets?
The Colts have not won in Jacksonville since 2014, which includes several blowout losses. Historically, Jacksonville has had a stronghold against Indianapolis at home, making this a difficult spot for the Colts despite the Jaguars’ poor form this season.
What are Indianapolis trending bets?
IND trend: The Colts are 2-2 ATS (Against the Spread) this season. They have covered in their last two games, showing resilience and the ability to close out tightly contested matchups, particularly when playing as slight underdogs.
What are Jacksonville trending bets?
JAC trend: The Jaguars have struggled against the spread, going 0-4 ATS so far this season. Despite a few close calls, Jacksonville has been unable to cover, largely due to their defensive issues, allowing 27.3 points per game and struggling to stop opponents in critical situations.
Where can I find AI Picks for Indianapolis vs Jacksonville?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Indianapolis vs. Jacksonville Odds
AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Indianapolis vs Jacksonville trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.
Indianapolis vs Jacksonville Opening Odds
IND Moneyline:
+125 JAC Moneyline: -148
IND Spread: +2.5
JAC Spread: -2.5
Over/Under: 46
Indianapolis vs Jacksonville Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
|
–
–
|
+142
-165
|
+3 (-110)
-3 (-110)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
|
–
–
|
+290
-360
|
+7 (-110)
-7 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-400
+320
|
-7.5 (-110)
+7.5 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
|
+250
-300
|
+6.5 (-105)
-6.5 (-115)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+265
-325
|
+7 (-120)
-7 (+100)
|
O 50 (-110)
U 50 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+290
-360
|
+7 (-105)
-7 (-115)
|
O 43.5 (-115)
U 43.5 (-105)
|
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-110
-106
|
-1.5 (-104)
+1.5 (-118)
|
O 41.5 (-115)
U 41.5 (-105)
|
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+280
-350
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-220
+184
|
-4.5 (-112)
+4.5 (-108)
|
O 47.5 (-105)
U 47.5 (-115)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+146
-170
|
+3 (+100)
-3 (-120)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+750
-1200
|
+14 (-110)
-14 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-185
+159
|
-3.5 (-105)
+3.5 (-115)
|
O 45 (-113)
U 45 (-107)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+465
-630
|
+10.5 (-115)
-10.5 (-105)
|
O 48.5 (-110)
U 48.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indianapolis Colts vs. Jacksonville Jaguars on October 06, 2024 at EverBank Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |