Bills vs Texans Prediction — AI Finds CAN'T MISS NFL Lines & Props (Oct 06)
Updated: 2024-09-29T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Buffalo Bills will take on the Houston Texans on October 6, 2024, at NRG Stadium in Houston, Texas. The Bills come into this matchup looking to rebound after a tough loss to the Baltimore Ravens, while the Texans aim to build on a close victory over the Jacksonville Jaguars. Both teams stand at 3-1, making this game crucial for positioning within their respective divisions.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 06, 2024
Start Time: 1:00 PM EST
Venue: NRG Stadium
Texans Record: (3-1)
Bills Record: (3-1)
OPENING ODDS
BUF Moneyline: -103
HOU Moneyline: -117
BUF Spread: +1
HOU Spread: -1.0
Over/Under: 47
BUF
Betting Trends
- The Buffalo Bills are 2-1 against the spread (ATS) this season. They have been consistent in covering the spread in their victories, particularly when their offense has managed to score over 30 points.
HOU
Betting Trends
- The Houston Texans have struggled against the spread, going 0-3 ATS so far. Despite being competitive in most games, they have failed to cover due to late-game collapses and inconsistent defensive play.
MATCHUP TRENDS
- The Texans are 0-3 ATS at home when playing against AFC East opponents in the past two seasons, making this a difficult spot for them to turn things around, especially against a high-scoring Bills team.
BUF vs. HOU
Best Prop Bet
- Remi's searched hard and found a NFL AI prop bet for this matchup: Josh Allen Over 20.5 Passing Completions
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Buffalo vs Houston Prediction & Odds:
Free NFL Betting Insights for 10/6/24
Their rushing attack, anchored by James Cook, provides a balanced offensive threat. Defensively, the Bills have been up and down, allowing 20.8 points per game, but they have struggled against teams that can establish a strong ground game. Houston, on the other hand, has been carried by the emergence of C.J. Stroud, who has thrown for 1,054 yards and 6 touchdowns. Nico Collins has been his go-to receiver, racking up 489 receiving yards and 3 touchdowns so far. Despite their offensive success, the Texans’ defense has been inconsistent, giving up 23.5 points per game and struggling against power running teams. For Houston to win, they need to control the tempo and limit the number of possessions for Buffalo’s high-octane offense.
"I expect Terrel Bernard to practice at some point during the week, while Taron Johnson is more of a question mark."
— Buffalo Bills (@BuffaloBills) September 30, 2024
Coach McDermott provides an injury update and other insights after Week 4: https://t.co/lYgfM6lMv1 pic.twitter.com/9g3MAYhn5M
Buffalo Bills NFL Preview
The Buffalo Bills come into this game looking to rebound after a disappointing performance against the Baltimore Ravens. Josh Allen has been the engine of the Bills’ offense, accounting for 9 total touchdowns and over 800 passing yards. Buffalo’s offense has been balanced, with James Cook providing a solid presence in the run game, averaging 4.1 yards per carry. Wide receiver Khalil Shakir has stepped up as a reliable target, contributing 230 receiving yards. Defensively, the Bills have been up and down. While they have been stout against the pass, allowing only 165.3 yards per game, they have struggled mightily against the run, giving up 156.5 yards per game on the ground. This could be a concern against a Texans team that may look to establish Joe Mixon early to open up the play-action game for Stroud. Buffalo’s path to victory will involve shutting down Houston’s passing attack and forcing them to be one-dimensional. In summary, this game will likely come down to whether Houston can protect Stroud and generate some semblance of a running game against a shaky Bills run defense. If they can, the Texans might keep it close, but if Buffalo’s offense gets into a rhythm, it could be a long day for the Houston defense.

Credit: USA TODAY/IMAGN
Houston Texans NFL Preview
The Houston Texans have surprised many this season, standing at 3-1 and sitting atop the AFC South. Rookie quarterback C.J. Stroud has been the driving force behind their resurgence, displaying poise and precision well beyond his years. Stroud has already thrown for 1,054 yards and 6 touchdowns, making him one of the top-performing rookies this season. His chemistry with Nico Collins, who has 489 receiving yards and 3 touchdowns, has transformed Houston’s offense into a dynamic passing unit. However, the Texans’ ground game, led by Joe Mixon, has been inconsistent, averaging just 106.8 rushing yards per game. Their inability to establish the run has put more pressure on Stroud to carry the offense. Defensively, Houston has been vulnerable against the pass, allowing 161 passing yards per game, and the unit has struggled to generate turnovers. The key for the Texans will be to slow down the game, sustain long drives, and keep Josh Allen off the field.
.@CJ7STROUD making this world a better place 🤞 pic.twitter.com/0mW0ppkMQq
— Houston Texans (@HoustonTexans) October 2, 2024
Buffalo vs. Houston Prop Picks (AI)
Buffalo vs. Houston Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every angle between the Bills and Texans and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
The Algorithm has been most watching on the growing weight knucklehead sportsbettors tend to put on coaching factors between a Bills team going up against a possibly tired Texans team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Buffalo vs Houston picks, computer picks Bills vs Texans, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Bills Betting Trends
The Buffalo Bills are 2-1 against the spread (ATS) this season. They have been consistent in covering the spread in their victories, particularly when their offense has managed to score over 30 points.
Texans Betting Trends
The Houston Texans have struggled against the spread, going 0-3 ATS so far. Despite being competitive in most games, they have failed to cover due to late-game collapses and inconsistent defensive play.
Bills vs. Texans Matchup Trends
The Texans are 0-3 ATS at home when playing against AFC East opponents in the past two seasons, making this a difficult spot for them to turn things around, especially against a high-scoring Bills team.
Buffalo vs. Houston Game Info
What time does Buffalo vs Houston start on October 06, 2024?
Buffalo vs Houston starts on October 06, 2024 at 1:00 PM EST.
Where is Buffalo vs Houston being played?
Venue: NRG Stadium.
What are the opening odds for Buffalo vs Houston?
Spread: Houston -1.0
Moneyline: Buffalo -103, Houston -117
Over/Under: 47
What are the records for Buffalo vs Houston?
Buffalo: (3-1) | Houston: (3-1)
What is the AI best bet for Buffalo vs Houston?
Remi's searched hard and found a NFL AI prop bet for this matchup: Josh Allen Over 20.5 Passing Completions. Prices move—always shop for the best number.
What are Buffalo vs Houston trending bets?
The Texans are 0-3 ATS at home when playing against AFC East opponents in the past two seasons, making this a difficult spot for them to turn things around, especially against a high-scoring Bills team.
What are Buffalo trending bets?
BUF trend: The Buffalo Bills are 2-1 against the spread (ATS) this season. They have been consistent in covering the spread in their victories, particularly when their offense has managed to score over 30 points.
What are Houston trending bets?
HOU trend: The Houston Texans have struggled against the spread, going 0-3 ATS so far. Despite being competitive in most games, they have failed to cover due to late-game collapses and inconsistent defensive play.
Where can I find AI Picks for Buffalo vs Houston?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Buffalo vs. Houston Odds
Remi is pouring through loads of data on each team. In fact, anytime the Buffalo vs Houston trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
Buffalo vs Houston Opening Odds
BUF Moneyline:
-103 HOU Moneyline: -117
BUF Spread: +1
HOU Spread: -1.0
Over/Under: 47
Buffalo vs Houston Live Odds
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–
–
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+142
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+3 (-110)
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O 45 (-110)
U 45 (-110)
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Patriots
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O 40.5 (-110)
U 40.5 (-110)
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Buffalo Bills
Carolina Panthers
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–
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-400
+320
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-7.5 (-110)
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O 45.5 (-110)
U 45.5 (-110)
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New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
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–
–
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+250
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+6.5 (-105)
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O 44.5 (-105)
U 44.5 (-115)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
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–
–
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+265
-325
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+7 (-120)
-7 (+100)
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O 50 (-110)
U 50 (-110)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
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–
–
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+290
-360
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+7 (-105)
-7 (-115)
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O 43.5 (-115)
U 43.5 (-105)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
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–
–
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-110
-106
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-1.5 (-104)
+1.5 (-118)
|
O 41.5 (-115)
U 41.5 (-105)
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
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–
–
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+280
-350
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+7 (-110)
-7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
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–
–
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-220
+184
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-4.5 (-112)
+4.5 (-108)
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O 47.5 (-105)
U 47.5 (-115)
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Oct 26, 2025 4:25PM EDT
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Denver Broncos
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Cowboys
Broncos
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–
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+146
-170
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+3 (+100)
-3 (-120)
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O 49.5 (-110)
U 49.5 (-110)
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
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Titans
Colts
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–
–
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+750
-1200
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+14 (-110)
-14 (-110)
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O 47 (-110)
U 47 (-110)
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Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
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–
–
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-185
+159
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-3.5 (-105)
+3.5 (-115)
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O 45 (-113)
U 45 (-107)
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
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Commanders
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–
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+465
-630
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+10.5 (-115)
-10.5 (-105)
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O 48.5 (-110)
U 48.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Buffalo Bills vs. Houston Texans on October 06, 2024 at NRG Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |