Commanders vs. Cardinals
Prediction, Odds & Props
Sep 29 | NFL AI Picks
Updated: 2024-09-22T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Washington Commanders travel to face the Arizona Cardinals on September 29, 2024, at State Farm Stadium. The Commanders come in with a 2-1 record, while the Cardinals, at 1-2, are trying to bounce back from a tough loss to the Lions.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 29, 2024
Start Time: 4:05 PM EST​
Venue: State Farm Stadium​
Cardinals Record: (2-1)
Commanders Record: (2-1)
OPENING ODDS
WAS Moneyline: +160
ARI Moneyline: -191
WAS Spread: +3.5
ARI Spread: -3.5
Over/Under: 50.5
WAS
Betting Trends
- Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.
ARI
Betting Trends
- Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.
MATCHUP TRENDS
- The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.
WAS vs. ARI
Best Prop Bet
- Remi's searched hard and found the best Prop Bet for this matchup: James Conner Over 67.5 Rushing Yards
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Washington vs Arizona Prediction & Odds:
Free NFL Betting Insights for 9/29/24
On the other side, the Cardinals enter with a 1-2 record, following a 20-13 loss to the Detroit Lions. Arizona has been inconsistent, but Kyler Murray’s return from injury has provided a spark for their offense. The Cardinals will rely heavily on Murray and running back James Conner to create opportunities against a Washington defense that has struggled, allowing 29.3 points per game. Washington’s defense will be key in this matchup, particularly in containing the dual-threat capabilities of Murray. If they can generate pressure, their secondary, led by Emmanuel Forbes, will have opportunities to force turnovers. On offense, Daniels’ connection with Terry McLaurin and the resurgence of running back Brian Robinson Jr. will be pivotal in keeping the Commanders’ balanced attack moving. Arizona’s defense, which has allowed 21.3 points per game, will need to find ways to slow down Washington’s high-powered offense. Led by Dennis Gardeck, who has three sacks on the season, the Cardinals will look to disrupt Daniels in the pocket. With the Cardinals slightly favored at home, this game could come down to which team capitalizes on key defensive stops. The Cardinals’ home-field advantage and their recent success ATS against NFC East opponents give them a slight edge, but Washington’s offensive firepower cannot be overlooked.
A historic performance@MDLottery | #RaiseHail
— Washington Commanders (@Commanders) September 24, 2024
Washington Commanders NFL Preview
The Washington Commanders come into this game riding high after a 38-33 victory over the Cincinnati Bengals, improving to 2-1 on the season. Quarterback Jayden Daniels has been impressive, throwing for over 660 yards and five touchdowns while also making plays with his legs. The Commanders’ offense has averaged 26.3 points per game, with running back Brian Robinson Jr. providing balance on the ground, rushing for 206 yards through three games. Wide receiver Terry McLaurin remains a key weapon for Daniels, with 139 receiving yards so far. The Commanders will look to exploit Arizona’s secondary, particularly if Daniels can buy time in the pocket and spread the ball around. The offensive line’s performance will be crucial, as Arizona’s defense has shown the ability to get after the quarterback. Defensively, Washington has struggled, allowing 29.3 points per game, and will need to tighten up if they hope to stop Kyler Murray and the Cardinals’ offense. The Commanders’ secondary, led by Emmanuel Forbes, will be tested by Arizona’s passing attack, but generating pressure on Murray will be critical to their success. If Washington can force turnovers and keep Arizona’s offense off the field, they have a good chance to improve to 3-1.

Credit: USA TODAY/IMAGN
Arizona Cardinals NFL Preview
The Arizona Cardinals enter Week 4 looking to bounce back from a tough 20-13 loss to the Detroit Lions. Kyler Murray, who has thrown for 635 yards and five touchdowns so far this season, will once again be the focal point of the Cardinals’ offense. Murray’s mobility and ability to extend plays with his legs have been crucial to Arizona’s success, but they will need a more consistent performance from their offensive line, which has struggled to protect him in key moments. Running back James Conner will be an important piece of the Cardinals’ game plan. Conner has rushed for 189 yards through three games and will need to keep the Washington defense honest by establishing the ground game early. Wide receiver Marvin Harrison Jr. has emerged as a key target for Murray, leading the team with 198 receiving yards. Defensively, Arizona’s front seven has shown flashes of potential, with Dennis Gardeck leading the way with three sacks. The Cardinals will need to pressure Jayden Daniels and prevent Washington from establishing a rhythm on offense. Arizona’s defense has allowed an average of 21.3 points per game, but their ability to force turnovers and create pressure could be the difference in this contest.
Mack Sack Wilson pic.twitter.com/P9kXXqU92J
— Arizona Cardinals (@AZCardinals) September 24, 2024
Washington vs. Arizona Prop Picks (AI)
Washington vs. Arizona Prediction (AI)

Remi, our AI sports algorithm, has been pouring over millions of data from every past game between the Commanders and Cardinals and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most focused on the unproportionally assigned factor human bettors tend to put on Arizona’s strength factors between a Commanders team going up against a possibly improved Cardinals team. It appears the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Washington vs Arizona picks, computer picks Commanders vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 9/28 | LAC@NYG | UNLOCK THIS PICK | 7 |
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NFL | 9/28 | TEN@HOU | UNLOCK THIS PICK | 7 |
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NFL | 9/28 | CAR@NE | UNLOCK THIS PICK | 6 |
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NFL | 9/28 | BAL@KC | UNLOCK THIS PICK | 6 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 5 |
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NFL | 9/28 | WAS@ATL | UNLOCK THIS PICK | 4 |
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NFL | 9/28 | NO@BUF | UNLOCK THIS PICK | 3 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 2 |
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NFL | 9/28 | CHI@LV | GET FREE PICK NOW | 2 | – | |
NFL | 9/28 | PHI@TB | UNLOCK THIS PICK | 10 |
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NFL | 9/28 | BAL@KC | UNLOCK THIS PICK | 0 |
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NFL | 9/28 | IND@LAR | UNLOCK THIS PICK | 1 |
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NFL | 9/28 | CAR@NE | UNLOCK THIS PICK | 0 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Commanders Betting Trends
Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.
Cardinals Betting Trends
Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.
Commanders vs. Cardinals Matchup Trends
The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.
Washington vs. Arizona Game Info
What time does Washington vs Arizona start on September 29, 2024?
Washington vs Arizona starts on September 29, 2024 at 4:05 PM EST.
Where is Washington vs Arizona being played?
Venue: State Farm Stadium.
What are the opening odds for Washington vs Arizona?
Spread: Arizona -3.5
Moneyline: Washington +160, Arizona -191
Over/Under: 50.5
What are the records for Washington vs Arizona?
Washington: (2-1) Â |Â Arizona: (2-1)
What is the AI best bet for Washington vs Arizona?
Remi's searched hard and found the best Prop Bet for this matchup: James Conner Over 67.5 Rushing Yards. Prices move—always shop for the best number.
What are Washington vs Arizona trending bets?
The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.
What are Washington trending bets?
WAS trend: Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.
What are Arizona trending bets?
ARI trend: Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.
Where can I find AI Picks for Washington vs Arizona?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Washington vs. Arizona Odds
Remi is pouring through tons of data points on each player. In fact, anytime the Washington vs Arizona trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.
Washington vs Arizona Opening Odds
WAS Moneyline:
+160 ARI Moneyline: -191
WAS Spread: +3.5
ARI Spread: -3.5
Over/Under: 50.5
Washington vs Arizona Live Odds
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–
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-355
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-6.5 (-106)
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O 47 (-102)
U 47 (-113)
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+125
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U 44.5 (-109)
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–
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+344
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O 44 (-113)
U 44 (-102)
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Oct 2, 2025 7:16PM EDT
San Francisco 49ers
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–
–
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+145
-175
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+3.5 (-110)
-3.5 (+100)
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O 46.5 (-113)
U 46.5 (-102)
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Oct 5, 2025 8:31AM EDT
Minnesota Vikings
Cleveland Browns
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Vikings
Browns
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–
–
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-205
+172
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-4 (-110)
+4 (+100)
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O 37.5 (-102)
U 37.5 (-113)
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Oct 5, 2025 12:01PM EDT
Las Vegas Raiders
Indianapolis Colts
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Raiders
Colts
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–
–
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+265
-330
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+6.5 (+103)
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O 49 (-107)
U 49 (-107)
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Oct 5, 2025 12:01PM EDT
New York Giants
New Orleans Saints
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Giants
Saints
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–
–
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-134
+114
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-1 (-114)
+1 (+103)
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O 42.5 (-107)
U 42.5 (-107)
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Oct 5, 2025 12:01PM EDT
Denver Broncos
Philadelphia Eagles
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Broncos
Eagles
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–
–
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+194
-235
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+5.5 (-105)
-5.5 (-105)
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O 44 (-107)
U 44 (-107)
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Oct 5, 2025 12:01PM EDT
Dallas Cowboys
New York Jets
10/5/25 12:01PM
Cowboys
Jets
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–
–
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-122
+104
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-1.5 (-105)
+1.5 (-105)
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O 46 (-107)
U 46 (-107)
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Oct 5, 2025 12:01PM EDT
Miami Dolphins
Carolina Panthers
10/5/25 12:01PM
Dolphins
Panthers
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–
–
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-130
+110
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-1 (-105)
+1 (-105)
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O 45.5 (-102)
U 45.5 (-113)
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Oct 5, 2025 3:06PM EDT
Tampa Bay Buccaneers
Seattle Seahawks
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Buccaneers
Seahawks
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–
–
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+124
-146
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+3 (-116)
-3 (+105)
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O 44 (-107)
U 44 (-107)
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Oct 5, 2025 3:06PM EDT
Tennessee Titans
Arizona Cardinals
10/5/25 3:06PM
Titans
Cardinals
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–
–
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+400
-520
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+9 (+100)
-9 (-110)
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O 41 (-102)
U 41 (-113)
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Oct 5, 2025 3:26PM EDT
Washington Commanders
Los Angeles Chargers
10/5/25 3:26PM
Commanders
Chargers
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–
–
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+130
-154
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+3 (-118)
-3 (-104)
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O 49.5 (-105)
U 49.5 (-115)
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Oct 5, 2025 3:26PM EDT
Detroit Lions
Cincinnati Bengals
10/5/25 3:26PM
Lions
Bengals
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–
–
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-450
+350
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-8.5 (-105)
+8.5 (-105)
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O 49.5 (-102)
U 49.5 (-113)
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Oct 5, 2025 7:21PM EDT
New England Patriots
Buffalo Bills
10/5/25 7:21PM
Patriots
Bills
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–
–
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+375
-500
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+9 (+100)
-9 (-110)
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O 49.5 (-107)
U 49.5 (-107)
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Oct 6, 2025 7:16PM EDT
Kansas City Chiefs
Jacksonville Jaguars
10/6/25 7:16PM
Chiefs
Jaguars
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–
–
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-154
+130
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-3 (+105)
+3 (-116)
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O 45 (-107)
U 45 (-107)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Washington Commanders vs. Arizona Cardinals on September 29, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |
GB@CLE | GB -7 | 54.3% | 4 | LOSS |
ARI@SF | ARI +3 | 57.7% | 6 | WIN |
KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
LAC@LV | LAC -3 | 54.9% | 4 | WIN |
TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
PHI@KC | PHI -115 | 56.7% | 6 | WIN |
SF@NO | SF -3 | 58.8% | 8 | WIN |
SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
SF@SEA | SF -115 | 54.6% | 4 | WIN |
SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |