Commanders vs Cardinals Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 29)

Updated: 2024-09-22T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Washington Commanders travel to face the Arizona Cardinals on September 29, 2024, at State Farm Stadium. The Commanders come in with a 2-1 record, while the Cardinals, at 1-2, are trying to bounce back from a tough loss to the Lions.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 29, 2024

Start Time: 4:05 PM EST​

Venue: State Farm Stadium​

Cardinals Record: (2-1)

Commanders Record: (2-1)

OPENING ODDS

WAS Moneyline: +160

ARI Moneyline: -191

WAS Spread: +3.5

ARI Spread: -3.5

Over/Under: 50.5

WAS
Betting Trends

  • Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.

ARI
Betting Trends

  • Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.

MATCHUP TRENDS

  • The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.

WAS vs. ARI
Best Prop Bet

  • Remi's searched hard and found the best Prop Bet for this matchup: James Conner Over 67.5 Rushing Yards

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Washington vs Arizona Prediction & Odds:
Free NFL Betting Insights for 9/29/24

The Week 4 matchup between the Washington Commanders and Arizona Cardinals presents an intriguing clash between two teams seeking early-season momentum. Washington comes into this contest with a 2-1 record, fresh off a thrilling 38-33 win over the Cincinnati Bengals. Quarterback Jayden Daniels has been efficient, throwing for over 600 yards and five touchdowns while showcasing his ability to extend plays with his legs.

On the other side, the Cardinals enter with a 1-2 record, following a 20-13 loss to the Detroit Lions. Arizona has been inconsistent, but Kyler Murray’s return from injury has provided a spark for their offense. The Cardinals will rely heavily on Murray and running back James Conner to create opportunities against a Washington defense that has struggled, allowing 29.3 points per game. Washington’s defense will be key in this matchup, particularly in containing the dual-threat capabilities of Murray. If they can generate pressure, their secondary, led by Emmanuel Forbes, will have opportunities to force turnovers. On offense, Daniels’ connection with Terry McLaurin and the resurgence of running back Brian Robinson Jr. will be pivotal in keeping the Commanders’ balanced attack moving. Arizona’s defense, which has allowed 21.3 points per game, will need to find ways to slow down Washington’s high-powered offense. Led by Dennis Gardeck, who has three sacks on the season, the Cardinals will look to disrupt Daniels in the pocket. With the Cardinals slightly favored at home, this game could come down to which team capitalizes on key defensive stops. The Cardinals’ home-field advantage and their recent success ATS against NFC East opponents give them a slight edge, but Washington’s offensive firepower cannot be overlooked.

Washington Commanders NFL Preview

The Washington Commanders come into this game riding high after a 38-33 victory over the Cincinnati Bengals, improving to 2-1 on the season. Quarterback Jayden Daniels has been impressive, throwing for over 660 yards and five touchdowns while also making plays with his legs. The Commanders’ offense has averaged 26.3 points per game, with running back Brian Robinson Jr. providing balance on the ground, rushing for 206 yards through three games. Wide receiver Terry McLaurin remains a key weapon for Daniels, with 139 receiving yards so far. The Commanders will look to exploit Arizona’s secondary, particularly if Daniels can buy time in the pocket and spread the ball around. The offensive line’s performance will be crucial, as Arizona’s defense has shown the ability to get after the quarterback. Defensively, Washington has struggled, allowing 29.3 points per game, and will need to tighten up if they hope to stop Kyler Murray and the Cardinals’ offense. The Commanders’ secondary, led by Emmanuel Forbes, will be tested by Arizona’s passing attack, but generating pressure on Murray will be critical to their success. If Washington can force turnovers and keep Arizona’s offense off the field, they have a good chance to improve to 3-1.

The Washington Commanders travel to face the Arizona Cardinals on September 29, 2024, at State Farm Stadium. The Commanders come in with a 2-1 record, while the Cardinals, at 1-2, are trying to bounce back from a tough loss to the Lions. Washington vs Arizona AI Prediction: Free NFL Betting Insights for Sep 29. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Arizona Cardinals NFL Preview

The Arizona Cardinals enter Week 4 looking to bounce back from a tough 20-13 loss to the Detroit Lions. Kyler Murray, who has thrown for 635 yards and five touchdowns so far this season, will once again be the focal point of the Cardinals’ offense. Murray’s mobility and ability to extend plays with his legs have been crucial to Arizona’s success, but they will need a more consistent performance from their offensive line, which has struggled to protect him in key moments. Running back James Conner will be an important piece of the Cardinals’ game plan. Conner has rushed for 189 yards through three games and will need to keep the Washington defense honest by establishing the ground game early. Wide receiver Marvin Harrison Jr. has emerged as a key target for Murray, leading the team with 198 receiving yards. Defensively, Arizona’s front seven has shown flashes of potential, with Dennis Gardeck leading the way with three sacks. The Cardinals will need to pressure Jayden Daniels and prevent Washington from establishing a rhythm on offense. Arizona’s defense has allowed an average of 21.3 points per game, but their ability to force turnovers and create pressure could be the difference in this contest.

Washington vs. Arizona Prop Picks (AI)

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Commanders and Cardinals play there’s always several intriguing angles to key in on. Not to mention games played at State Farm Stadium in Sep rarely follow normal, predictable betting trends.
Remi's searched hard and found the best Prop Bet for this matchup: James Conner Over 67.5 Rushing Yards

Washington vs. Arizona Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Commanders and Cardinals and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Interestingly enough, the data has been most watching on the unproportionally assigned weight human bettors regularly put on player performance factors between a Commanders team going up against a possibly tired Cardinals team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Washington vs Arizona picks, computer picks Commanders vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 11/10 PHI@GB UNLOCK THIS PICK 6 VAULT v3 Locked VAULT v3
NFL 11/10 PHI@GB UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 11/10 PHI@GB UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 11/10 PHI@GB UNLOCK THIS PICK 1 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Commanders Betting Trends

Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.

Cardinals Betting Trends

Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.

Commanders vs. Cardinals Matchup Trends

The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.

Washington vs. Arizona Game Info

Washington vs Arizona starts on September 29, 2024 at 4:05 PM EST.

Spread: Arizona -3.5
Moneyline: Washington +160, Arizona -191
Over/Under: 50.5

Washington: (2-1)  |  Arizona: (2-1)

Remi's searched hard and found the best Prop Bet for this matchup: James Conner Over 67.5 Rushing Yards. Prices move—always shop for the best number.

The total has gone UNDER in 6 of the last 8 games between these teams when playing in Arizona, indicating a trend toward lower-scoring games when the Commanders visit.

WAS trend: Washington has been strong ATS in recent games, going 2-1 this season. However, they have struggled against NFC West opponents, going 1-4 ATS in their last five matchups against teams in that division.

ARI trend: Arizona is 4-1 ATS in their last five games and has covered the spread in all but one home game this season. They are also 11-0 ATS in their last 11 games against NFC East opponents, showcasing their ability to compete in inter-conference matchups.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Washington vs. Arizona Odds

AI algorithm Remi is pouring through loads of data on each player. In fact, anytime the Washington vs Arizona trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.

Washington vs Arizona Opening Odds

WAS Moneyline: +160
ARI Moneyline: -191
WAS Spread: +3.5
ARI Spread: -3.5
Over/Under: 50.5

Washington vs Arizona Live Odds

Games PTS ML SPR O/U
Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
+550
-800
+11.5 (-110)
-11.5 (-110)
O 43.5 (-110)
U 43.5 (-110)
Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
+124
-148
+2.5 (-105)
-2.5 (-115)
O 47.5 (-112)
U 47.5 (-108)
Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
+160
-192
+3.5 (-110)
-3.5 (-110)
O 42.5 (-115)
U 42.5 (-105)
Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
+140
-166
+3 (-112)
-3 (-108)
O 48.5 (-110)
U 48.5 (-110)
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
-148
+124
-3 (-102)
+3 (-118)
O 43.5 (-118)
U 43.5 (-102)
Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
-395
+310
-7.5 (-112)
+7.5 (-108)
O 44.5 (-105)
U 44.5 (-115)
Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
+185
-225
+5.5 (-115)
-5.5 (-105)
O 49.5 (-112)
U 49.5 (-108)
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
+200
-245
+5.5 (-110)
-5.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
-375
+295
-7.5 (-110)
+7.5 (-110)
O 39.5 (-110)
U 39.5 (-110)
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
-148
+124
-2.5 (-115)
+2.5 (-105)
O 48.5 (-115)
U 48.5 (-105)
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-108)
U 48.5 (-112)
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
-185
+154
-3.5 (-110)
+3.5 (-110)
O 43.5 (-115)
U 43.5 (-105)
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
-470
+360
-8.5 (-105)
+8.5 (-115)
O 41.5 (-108)
U 41.5 (-112)
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
+102
-122
+1.5 (-110)
-1.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
-192
+160
-3.5 (-110)
+3.5 (-110)
O 50.5 (-110)
U 50.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Washington Commanders vs. Arizona Cardinals on September 29, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
LV@DEN RILEY MOSS OVER 4.5 TACKLE + ASST 54.8% 4 WIN
LV@DEN UNDER 43 53.4% 2 WIN
ARI@DAL BUDDA BAKER OVER 7.5 TACKLES + ASSTS 54.4% 4 WIN
ARI@DAL GEORGE PICKENS OVER 4.5 RECEPTIONS 56.6% 6 WIN
DEN@HOU WIL LUTZ OVER 1.5 MADE FIELD GOALS 54.2% 3 LOSS
SEA@WAS SEA -3 56.7% 6 WIN
IND@PIT IND -3 56.8% 6 LOSS
LAC@TEN LAC -9.5 56.2% 6 LOSS
CHI@CIN CHI -2.5 52.6% 2 WIN
SEA@WAS OVER 48 52.9% 2 WIN
SEA@WAS JAYDEN DANIELS OVER 20.5 PASS COMP 56.7% 6 LOSS
JAC@LV JAC -140 64.2% 7 WIN
NO@LAR LAR -14 55.0% 4 WIN
DEN@HOU HOU -1.5 54.2% 3 LOSS
CAR@GB GB -12.5 55.4% 5 LOSS
SF@NYG NYG +2.5 56.1% 5 LOSS
BAL@MIA TUA TAGOVAILOA UNDER 0.5 INT 55.3% 5 LOSS
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS
NYG@PHI NYG +7.5 53.9% 3 LOSS
BUF@CAR CAR +7.5 54.2% 3 LOSS
DAL@DEN DAL +3.5 55.0% 4 LOSS
MIA@ATL MIA +7 54.3% 4 WIN
CLE@NE CLE +7 56.8% 6 LOSS
TB@NO BAKER MAYFIELD OVER 15.5 RUSH YDS 56.6% 6 LOSS
MIN@LAC JUSTIN HERBERT PASS ATT UNDER 35.5 55.5% 5 WIN
TB@DET TB +6.5 54.4% 4 LOSS
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS