Eagles vs Saints Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 22)

Updated: 2024-09-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Philadelphia Eagles will face the New Orleans Saints at Caesars Superdome on September 22, 2024, in a crucial Week 3 matchup. The Eagles, coming off a narrow loss to the Atlanta Falcons, aim to rebound against a Saints team that has been dominant through two games, leading the NFL with a +62 point differential.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 22, 2024

Start Time: 1:00 PM EST​

Venue: Caesars Superdome​

Saints Record: (2-0)

Eagles Record: (1-1)

OPENING ODDS

PHI Moneyline: +126

NO Moneyline: -149

PHI Spread: +2.5

NO Spread: -2.5

Over/Under: 49.5

PHI
Betting Trends

  • The Eagles are 1-1 against the spread (ATS) this season and have struggled in games following a road loss, covering the spread in only three of their last eight games under these conditions. Their last nine road games have mostly gone under the total points line.

NO
Betting Trends

  • The Saints have been solid ATS as home favorites, covering in four of their last five games. They have also excelled against NFC East opponents at home, with five of their last six such games going under the total points line.

MATCHUP TRENDS

  • The Eagles have given up points in every quarter in their games this season, and their defense has allowed an average of 399.5 yards per game, ranking 30th in the NFL. Meanwhile, the Saints have covered the spread in each of their last seven games against NFC opponents, showcasing their strong form both offensively and defensively.

PHI vs. NO
Best Prop Bet

  • Remi's searched hard and crunched the numbers and found the best prop bet play for this game: QB Derek Carr Under 229.5 Passing Yards

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Philadelphia vs New Orleans Prediction & Odds:
Free NFL Betting Insights for 9/22/24

The Philadelphia Eagles and New Orleans Saints are set for a compelling showdown in Week 3 of the NFL season at Caesars Superdome. The Eagles, at 1-1, are coming off a tough 22-21 loss to the Atlanta Falcons, a game in which they surrendered a late lead. Jalen Hurts and Saquon Barkley are the key players for Philadelphia, with Hurts showing his dual-threat capability by passing for 183 yards and rushing for 85 yards with a touchdown against Atlanta. However, the Eagles have faced challenges in the passing game without A.J. Brown, who is expected to miss the Saints game as well. The defense, which allowed 385 yards to the Falcons, must step up to contain a high-flying Saints offense. The Saints, on the other hand, have been a revelation this season. At 2-0, they have dominated both the Carolina Panthers and the Dallas Cowboys, scoring a combined 91 points.

Quarterback Derek Carr has been exceptional, posting a league-leading 142.4 passer rating, and his connection with Alvin Kamara and Rashid Shaheed has been pivotal. Kamara leads the NFL with four rushing touchdowns, while Shaheed has been a reliable target, recording touchdowns in each of the last four games following a win. The Saints’ defense has also played a key role, holding opponents to minimal success, especially against the NFC East. This game will likely hinge on whether the Eagles’ defense can disrupt Carr and the Saints’ offensive rhythm, and if the Eagles can control the clock with their running game. The Saints will look to continue their hot streak and take advantage of the Eagles’ defensive vulnerabilities.

Philadelphia Eagles NFL Preview

The Philadelphia Eagles enter Week 3 with a 1-1 record and looking to bounce back after a disappointing loss to the Atlanta Falcons. In that game, Jalen Hurts demonstrated his ability to make plays with both his arm and legs, passing for 183 yards and rushing for 85 yards and a touchdown. However, the absence of A.J. Brown has limited the Eagles’ passing attack, forcing them to rely more on DeVonta Smith and their ground game. Saquon Barkley remains a key component of the offense, averaging over 4 yards per carry, but the Eagles need more from their passing game to challenge the Saints’ strong defense. Defensively, the Eagles have struggled, allowing an average of 399.5 yards per game and ranking 30th in the league. Their run defense has been particularly porous, giving up 157.5 rushing yards per game. Philadelphia’s secondary will also need to tighten up after giving up key plays in critical moments. Against a potent Saints offense, the Eagles will need to apply consistent pressure on Derek Carr and limit the effectiveness of Kamara and Shaheed. Philadelphia’s path to victory lies in controlling the clock with their rushing attack and creating turnovers on defense, which will be crucial against a Saints team firing on all cylinders.

The Philadelphia Eagles will face the New Orleans Saints at Caesars Superdome on September 22, 2024, in a crucial Week 3 matchup. The Eagles, coming off a narrow loss to the Atlanta Falcons, aim to rebound against a Saints team that has been dominant through two games, leading the NFL with a +62 point differential. Philadelphia vs New Orleans AI Prediction: Free NFL Betting Insights for Sep 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

New Orleans Saints NFL Preview

The New Orleans Saints come into this Week 3 matchup with a perfect 2-0 record, having dominated their opponents in the first two games of the season. Their offense, led by quarterback Derek Carr, has been on fire, scoring 91 points through two games. Carr has been highly efficient, throwing for over 230 yards in each of his last six September home appearances and completing two or more touchdowns in seven consecutive games against NFC opponents. Alvin Kamara has been another standout, leading the NFL with four rushing touchdowns. The Saints’ offensive line has provided excellent protection, allowing Carr to deliver precise throws downfield to targets like Rashid Shaheed, who has consistently recorded 65+ receiving yards following a win. Defensively, the Saints have been equally impressive. They have held their ground against both the Panthers and Cowboys, showcasing a balanced attack with strong pass rush and secondary coverage. Despite giving up some yardage, their ability to force turnovers and prevent scoring has been vital. The Saints will focus on pressuring Jalen Hurts and containing Saquon Barkley, the Eagles’ primary offensive threats. If the Saints can control the line of scrimmage and execute their game plan, they are well-positioned to extend their unbeaten run.

Philadelphia vs. New Orleans Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Eagles and Saints play there’s always several intriguing observations to key in on. Not to mention games played at Caesars Superdome in Sep almost always follow normal, predictable patterns.
Remi's searched hard and crunched the numbers and found the best prop bet play for this game: QB Derek Carr Under 229.5 Passing Yards

Philadelphia vs. New Orleans Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Eagles and Saints and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the linear correlation of factor emotional bettors often put on coaching factors between a Eagles team going up against a possibly deflated Saints team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Philadelphia vs New Orleans picks, computer picks Eagles vs Saints, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Eagles Betting Trends

The Eagles are 1-1 against the spread (ATS) this season and have struggled in games following a road loss, covering the spread in only three of their last eight games under these conditions. Their last nine road games have mostly gone under the total points line.

Saints Betting Trends

The Saints have been solid ATS as home favorites, covering in four of their last five games. They have also excelled against NFC East opponents at home, with five of their last six such games going under the total points line.

Eagles vs. Saints Matchup Trends

The Eagles have given up points in every quarter in their games this season, and their defense has allowed an average of 399.5 yards per game, ranking 30th in the NFL. Meanwhile, the Saints have covered the spread in each of their last seven games against NFC opponents, showcasing their strong form both offensively and defensively.

Philadelphia vs. New Orleans Game Info

Philadelphia vs New Orleans starts on September 22, 2024 at 1:00 PM EST.

Spread: New Orleans -2.5
Moneyline: Philadelphia +126, New Orleans -149
Over/Under: 49.5

Philadelphia: (1-1)  |  New Orleans: (2-0)

Remi's searched hard and crunched the numbers and found the best prop bet play for this game: QB Derek Carr Under 229.5 Passing Yards. Prices move—always shop for the best number.

The Eagles have given up points in every quarter in their games this season, and their defense has allowed an average of 399.5 yards per game, ranking 30th in the NFL. Meanwhile, the Saints have covered the spread in each of their last seven games against NFC opponents, showcasing their strong form both offensively and defensively.

PHI trend: The Eagles are 1-1 against the spread (ATS) this season and have struggled in games following a road loss, covering the spread in only three of their last eight games under these conditions. Their last nine road games have mostly gone under the total points line.

NO trend: The Saints have been solid ATS as home favorites, covering in four of their last five games. They have also excelled against NFC East opponents at home, with five of their last six such games going under the total points line.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Philadelphia vs. New Orleans Odds

AI algorithm Remi is pouring through loads of data on each line. In fact, anytime the Philadelphia vs New Orleans trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.

Philadelphia vs New Orleans Opening Odds

PHI Moneyline: +126
NO Moneyline: -149
PHI Spread: +2.5
NO Spread: -2.5
Over/Under: 49.5

Philadelphia vs New Orleans Live Odds

Games PTS ML SPR O/U
Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
+613
-900
+13 (-110)
-13 (-110)
O 43 (-110)
U 43 (-110)
Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
+135
-155
+3 (-115)
-3 (-105)
O 47.5 (-112)
U 47.5 (-108)
Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
+170
-195
+3.5 (-110)
-3.5 (-110)
O 42.5 (-110)
U 42.5 (-110)
Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
+149
-170
+3 (-103)
-3 (-117)
O 48.5 (-110)
U 48.5 (-110)
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
-155
+135
-3 (-105)
+3 (-115)
O 43.5 (-110)
U 43.5 (-110)
Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
-320
+260
-7 (-110)
+7 (-110)
O 43.5 (-105)
U 43.5 (-115)
Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
+200
-240
+5.5 (-115)
-5.5 (-105)
O 48.5 (-112)
U 48.5 (-108)
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
+215
-286
+5.5 (-112)
-5.5 (-113)
O 48 (-113)
U 48 (-113)
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
-365
+292
-7 (-113)
+7 (-107)
O 38.5 (-110)
U 38.5 (-110)
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
-140
+120
-2.5 (-110)
+2.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
+142
-162
+3 (-106)
-3 (-114)
O 48.5 (-108)
U 48.5 (-112)
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
-198
+173
-4 (-107)
+4 (-113)
O 44.5 (-105)
U 44.5 (-115)
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
-410
+324
-8 (-105)
+8 (-115)
O 39 (-115)
U 39 (-105)
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
+131
-151
+2.5 (-102)
-2.5 (-118)
O 46.5 (-110)
U 46.5 (-110)
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
-175
+153
-3.5 (+100)
+3.5 (-120)
O 50 (-110)
U 50 (-110)
Nov 20, 2025 8:15PM EST
Buffalo Bills
Houston Texans
11/20/25 8:15PM
Bills
Texans
-152
+128
-2.5 (-125)
+2.5 (+105)
O 44 (-110)
U 44 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Philadelphia Eagles vs. New Orleans Saints on September 22, 2024 at Caesars Superdome.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
PHI@GB PHI +1.5 54.8% 4 WIN
PHI@GB UNDER 45.5 52.4% 2 WIN
PHI@GB SAQUON BARKLEY OVER 17.5 RUSH ATT 56.6% 6 WIN
PHI@GB JOSH JACOBS UNDER 42.5 1ST HALF RUSH + REC YDS 54.4% 4 LOSS
NO@CAR CAR -5 55.4% 5 LOSS
BAL@MIN BAL -3.5 57.6% 7 WIN
CLE@NYJ CLE -130 65.4% 7 LOSS
NYG@CHI CHI -4.5 55.2% 5 LOSS
NE@TB TB -2 56.1% 6 LOSS
LAR@SF LAR -5.5 53.3% 2 WIN
JAC@HOU UNDER 38 54.8% 5 LOSS
ARI@SEA TREY MCBRIDE OVER 9 RECV TARGETS 55.8% 5 WIN
DET@WAS TERRION ARNOLD OVER 4.5 TACKLES + ASSTS 56.8% 6 LOSS
JAC@HOU TRAVIS ETIENNE UNDER 74.5 RUSH + REC YDS 54.4 4 LOSS
LV@DEN DANIEL CARLSON OVER 1.5 FIELD GOALS 55.2% 5 LOSS
LV@DEN COURTLAND SUTTON OVER 53.5 RECV YDS 54.2% 4 LOSS
LV@DEN RILEY MOSS OVER 4.5 TACKLE + ASST 54.8% 4 WIN
LV@DEN UNDER 43 53.4% 2 WIN
ARI@DAL BUDDA BAKER OVER 7.5 TACKLES + ASSTS 54.4% 4 WIN
ARI@DAL GEORGE PICKENS OVER 4.5 RECEPTIONS 56.6% 6 WIN
DEN@HOU WIL LUTZ OVER 1.5 MADE FIELD GOALS 54.2% 3 LOSS
SEA@WAS SEA -3 56.7% 6 WIN
IND@PIT IND -3 56.8% 6 LOSS
LAC@TEN LAC -9.5 56.2% 6 LOSS
CHI@CIN CHI -2.5 52.6% 2 WIN
SEA@WAS OVER 48 52.9% 2 WIN
SEA@WAS JAYDEN DANIELS OVER 20.5 PASS COMP 56.7% 6 LOSS
JAC@LV JAC -140 64.2% 7 WIN
NO@LAR LAR -14 55.0% 4 WIN
DEN@HOU HOU -1.5 54.2% 3 LOSS
CAR@GB GB -12.5 55.4% 5 LOSS
SF@NYG NYG +2.5 56.1% 5 LOSS
BAL@MIA TUA TAGOVAILOA UNDER 0.5 INT 55.3% 5 LOSS
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS
NYG@PHI NYG +7.5 53.9% 3 LOSS
BUF@CAR CAR +7.5 54.2% 3 LOSS
DAL@DEN DAL +3.5 55.0% 4 LOSS
MIA@ATL MIA +7 54.3% 4 WIN
CLE@NE CLE +7 56.8% 6 LOSS
TB@NO BAKER MAYFIELD OVER 15.5 RUSH YDS 56.6% 6 LOSS
MIN@LAC JUSTIN HERBERT PASS ATT UNDER 35.5 55.5% 5 WIN
TB@DET TB +6.5 54.4% 4 LOSS
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN