Giants vs. Browns
Prediction, Odds & Props
Sep 22 | NFL AI Picks
Updated: 2024-09-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The New York Giants will face the Cleveland Browns on September 22, 2024, at Huntington Bank Field. The Browns come in as 6-point favorites after a mixed start to the season, while the Giants are seeking their first win of the year.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 22, 2024
Start Time: 1:00 PM EST
Venue: Huntington Bank Field
Browns Record: (1-1)
Giants Record: (0-2)
OPENING ODDS
NYG Moneyline: +231
CLE Moneyline: -282
NYG Spread: +6.5
CLE Spread: -6.5
Over/Under: 38.5
NYG
Betting Trends
- The Giants have performed well as road underdogs, covering the spread in each of their last five games in such situations following a division game. However, they are 0-2 against the spread (ATS) this season and have struggled offensively.
CLE
Betting Trends
- The Browns have struggled ATS at home, failing to cover in three of their last four games. They also have a poor record against NFC East opponents, losing six of their last seven September games against this division.
MATCHUP TRENDS
- The total points line for each of the Giants’ last six September games as underdogs has gone under. Conversely, five of the Browns’ last six games have gone over the total points line, making the over/under a key factor to consider for this matchup.
NYG vs. CLE
Best Prop Bet
- Remi's searched hard and crunched the numbers and found the best prop bet play for this game: WR Amari Cooper Over 55.5 Receiving Yards
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New York Giants vs Cleveland Prediction & Odds:
Free NFL Betting Insights for 9/22/24
Cleveland’s ground game, led by Jerome Ford and Nick Chubb, has been more reliable, which could be crucial against a Giants defense that has allowed 326 rushing yards in two games. The Browns’ defense, featuring stalwarts like Myles Garrett and Jeremiah Owusu-Koramoah, needs to replicate their Week 2 performance to suppress the Giants’ offense. While the Browns have shown a better form in their last outing, their offensive inconsistencies, particularly on third down (only 13.8% conversion), could keep the game closer than expected.
On this day: In 2006, Plaxico Burress caught a game-winning TD for a 30-24 comeback OT win pic.twitter.com/zbemXik7tD
— New York Giants (@Giants) September 17, 2024
New York Giants Giants NFL Preview
The New York Giants head into Cleveland looking for their first win of the 2024 season. After starting 0-2, the Giants face an uphill battle, but their recent record as road underdogs gives them some hope. Quarterback Daniel Jones has shown flashes of potential but has also struggled with turnovers and inconsistency, particularly in the first game against the Vikings. Jones will need to be more accurate and avoid costly mistakes to keep the Giants competitive. The running game, led by Devin Singletary, has been a relative strength, with Singletary recording 95 rushing yards and a touchdown in the loss to the Commanders. Defensively, the Giants have not fared much better. They are giving up an average of 24.5 points per game and have been porous against the run, allowing 163 rushing yards per game. This is an area that needs immediate improvement, especially facing a Browns team that relies heavily on the ground attack. For the Giants to pull off an upset, their defense must contain Cleveland’s rushing duo of Chubb and Ford and force Watson into errors. The return to form of key defenders and more disciplined play overall will be crucial.
Credit: USA TODAY/IMAGN
Cleveland Browns NFL Preview
The Cleveland Browns aim to build on their recent victory as they host the New York Giants. After a shaky start to the season with a lopsided loss to the Dallas Cowboys, the Browns bounced back with a hard-fought win over the Jacksonville Jaguars. Quarterback Deshaun Watson, who has 355 passing yards with one touchdown and two interceptions so far, will need to be more efficient. The Browns’ offense has leaned heavily on the ground game, with Jerome Ford and Nick Chubb combining for significant yardage. Ford, in particular, has shown promise, and his ability to break through the Giants’ struggling run defense could be the key to the Browns controlling the game. Defensively, Cleveland’s unit has improved, allowing just 17.5 points per game. Myles Garrett, leading the pass rush, and Jeremiah Owusu-Koramoah, anchoring the linebacking corps, are critical in maintaining this defensive pressure. However, their vulnerability in the secondary and on third downs needs addressing. Against the Giants, the Browns’ defense will look to exploit the Giants’ offensive line woes and force turnovers, a category in which the Browns have excelled with a positive turnover margin in simulations.
We've placed WR David Bell on injured reserve
— Cleveland Browns (@Browns) September 17, 2024
📰 » https://t.co/SAdhkjb2Rv pic.twitter.com/lFpNx8ZKHf
New York Giants vs. Cleveland Prop Picks (AI)
New York Giants vs. Cleveland Prediction (AI)
Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every facet between the Giants and Browns and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Remi has been most fixated on the unproportionally assigned weight emotional bettors tend to put on Cleveland’s strength factors between a Giants team going up against a possibly strong Browns team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI New York Giants vs Cleveland picks, computer picks Giants vs Browns, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Giants Betting Trends
The Giants have performed well as road underdogs, covering the spread in each of their last five games in such situations following a division game. However, they are 0-2 against the spread (ATS) this season and have struggled offensively.
Browns Betting Trends
The Browns have struggled ATS at home, failing to cover in three of their last four games. They also have a poor record against NFC East opponents, losing six of their last seven September games against this division.
Giants vs. Browns Matchup Trends
The total points line for each of the Giants’ last six September games as underdogs has gone under. Conversely, five of the Browns’ last six games have gone over the total points line, making the over/under a key factor to consider for this matchup.
New York Giants vs. Cleveland Game Info
What time does New York Giants vs Cleveland start on September 22, 2024?
New York Giants vs Cleveland starts on September 22, 2024 at 1:00 PM EST.
Where is New York Giants vs Cleveland being played?
Venue: Huntington Bank Field.
What are the opening odds for New York Giants vs Cleveland?
Spread: Cleveland -6.5
Moneyline: New York Giants +231, Cleveland -282
Over/Under: 38.5
What are the records for New York Giants vs Cleveland?
New York Giants: (0-2) | Cleveland: (1-1)
What is the AI best bet for New York Giants vs Cleveland?
Remi's searched hard and crunched the numbers and found the best prop bet play for this game: WR Amari Cooper Over 55.5 Receiving Yards. Prices move—always shop for the best number.
What are New York Giants vs Cleveland trending bets?
The total points line for each of the Giants’ last six September games as underdogs has gone under. Conversely, five of the Browns’ last six games have gone over the total points line, making the over/under a key factor to consider for this matchup.
What are New York Giants trending bets?
NYG trend: The Giants have performed well as road underdogs, covering the spread in each of their last five games in such situations following a division game. However, they are 0-2 against the spread (ATS) this season and have struggled offensively.
What are Cleveland trending bets?
CLE trend: The Browns have struggled ATS at home, failing to cover in three of their last four games. They also have a poor record against NFC East opponents, losing six of their last seven September games against this division.
Where can I find AI Picks for New York Giants vs Cleveland?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
New York Giants vs. Cleveland Odds
Remi is pouring through mountains of data on each player. In fact, anytime the New York Giants vs Cleveland trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.
New York Giants vs Cleveland Opening Odds
NYG Moneyline:
+231 CLE Moneyline: -282
NYG Spread: +6.5
CLE Spread: -6.5
Over/Under: 38.5
New York Giants vs Cleveland Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Sep 28, 2025 9:31AM EDT
Minnesota Vikings
Pittsburgh Steelers
9/28/25 9:31AM
Vikings
Steelers
|
–
–
|
-140
+115
|
-2.5 (-115)
+2.5 (-105)
|
O 41 (-110)
U 41 (-110)
|
|
|
Sep 28, 2025 1:00PM EDT
Cleveland Browns
Detroit Lions
9/28/25 1PM
Browns
Lions
|
–
–
|
+400
-550
|
+10 (-110)
-10 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Sep 28, 2025 1:00PM EDT
Los Angeles Chargers
New York Giants
9/28/25 1PM
Chargers
Giants
|
–
–
|
-285
+230
|
-6.5 (-105)
+6.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Tennessee Titans
Houston Texans
9/28/25 1:01PM
Titans
Texans
|
–
–
|
+300
-375
|
+7 (-105)
-7 (-115)
|
O 39 (-110)
U 39 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Philadelphia Eagles
Tampa Bay Buccaneers
9/28/25 1:01PM
Eagles
Buccaneers
|
–
–
|
-190
+160
|
-3.5 (-105)
+3.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Washington Commanders
Atlanta Falcons
9/28/25 1:01PM
Commanders
Falcons
|
–
–
|
+105
-125
|
+2.5 (-110)
-2.5 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
New Orleans Saints
Buffalo Bills
9/28/25 1:01PM
Saints
Bills
|
–
–
|
+800
-1300
|
+15 (-110)
-15 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 1:01PM EDT
Carolina Panthers
New England Patriots
9/28/25 1:01PM
Panthers
Patriots
|
–
–
|
+200
-250
|
+5.5 (-110)
-5.5 (-110)
|
O 43.5 (-105)
U 43.5 (-115)
|
|
|
Sep 28, 2025 4:06PM EDT
Jacksonville Jaguars
San Francisco 49ers
9/28/25 4:06PM
Jaguars
49ers
|
–
–
|
+150
-180
|
+3.5 (-115)
-3.5 (-105)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Sep 28, 2025 4:06PM EDT
Indianapolis Colts
Los Angeles Rams
9/28/25 4:06PM
Colts
Rams
|
–
–
|
+160
-190
|
+3.5 (-110)
-3.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Sep 28, 2025 4:25PM EDT
Baltimore Ravens
Kansas City Chiefs
9/28/25 4:25PM
Ravens
Chiefs
|
–
–
|
-150
+125
|
-2.5 (-120)
+2.5 (+100)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Sep 28, 2025 4:26PM EDT
Chicago Bears
Las Vegas Raiders
9/28/25 4:26PM
Bears
Raiders
|
–
–
|
+100
-120
|
+1 (-110)
-1 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Sep 28, 2025 8:21PM EDT
Green Bay Packers
Dallas Cowboys
9/28/25 8:21PM
Packers
Cowboys
|
–
–
|
-325
+250
|
-7 (-105)
+7 (-115)
|
O 47 (-110)
U 47 (-110)
|
|
|
Sep 29, 2025 7:15PM EDT
New York Jets
Miami Dolphins
9/29/25 7:15PM
Jets
Dolphins
|
–
–
|
+125
-150
|
+3 (-115)
-3 (-105)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
|
Sep 29, 2025 8:15PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:15PM
Bengals
Broncos
|
–
–
|
+310
-400
|
+7.5 (-110)
-7.5 (-110)
|
O 44 (-110)
U 44 (-110)
|
|
|
Oct 2, 2025 8:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 8:16PM
49ers
Rams
|
–
–
|
+134
-158
|
+3 (-110)
-3 (-110)
|
O 47.5 (-105)
U 47.5 (-115)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers New York Giants Giants vs. Cleveland Browns on September 22, 2024 at Huntington Bank Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |
| GB@CLE | GB -7 | 54.3% | 4 | LOSS |
| ARI@SF | ARI +3 | 57.7% | 6 | WIN |
| KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
| GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
| MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
| LAC@LV | LAC -3 | 54.9% | 4 | WIN |
| TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
| CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
| DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
| PHI@KC | PHI -115 | 56.7% | 6 | WIN |
| SF@NO | SF -3 | 58.8% | 8 | WIN |
| SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
| CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
| DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
| ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
| WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
| WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
| MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
| TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
| SF@SEA | SF -115 | 54.6% | 4 | WIN |
| SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
| CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
| KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
| DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
| KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
| KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
| KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
| KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
| BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
| WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
| BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
| LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
| BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
| HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
| WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
| WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
| MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
| MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
| WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
| WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
| GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
| LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
| LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
| LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |