Broncos vs Buccaneers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 22)
Updated: 2024-09-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Denver Broncos will face the Tampa Bay Buccaneers on September 22, 2024, at Raymond James Stadium. The Buccaneers, coming off two wins, are looking to maintain their strong start, while the Broncos are searching for their first win of the season after a challenging start.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 22, 2024
Start Time: 1:00 PM EST
Venue: Raymond James Stadium
Buccaneers Record: (2-0)
Broncos Record: (0-2)
OPENING ODDS
DEN Moneyline: +252
TB Moneyline: -319
DEN Spread: +6.5
TB Spread: -6.5
Over/Under: 39.5
DEN
Betting Trends
- The Broncos have struggled on the road, failing to cover the spread in each of their last four Week 3 road games. They are also 0-2 against the spread (ATS) this season and have lost their last six away games against opponents on a winning streak.
TB
Betting Trends
- The Buccaneers have been solid ATS as home favorites, covering the spread in seven of their last eight games following a road win. They have also won each of their last 13 home games against opponents on a losing streak.
MATCHUP TRENDS
- The Buccaneers have won the first quarter in four of their last five games in Florida, while the favorites have won the first half in each of the Broncos’ last six Week 3 games. This trend suggests the Buccaneers could establish an early lead in this matchup.
DEN vs. TB
Best Prop Bet
- Remi's searched hard and crunched the numbers and found the best prop bet play for this game: QB Bo Nix Under 175 Passing Yards
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Denver vs Tampa Bay Prediction & Odds:
Free NFL Betting Insights for 9/22/24
The Denver Broncos, on the other hand, have started 0-2 and are struggling to find their footing under rookie quarterback Bo Nix. Nix has completed 59.7% of his passes for 384 yards but has yet to throw a touchdown and has four interceptions. The Broncos’ ground game has also been lackluster, averaging only 81.5 yards per game, with Nix leading the team in rushing yards. Defensively, the Broncos have been decent, allowing 19.5 points and 277.5 yards per game, but they have failed to capitalize on offensive opportunities, especially in the red zone, where they rank last in the NFL with a 14.3% conversion rate. For the Broncos to have a chance, they will need to find offensive rhythm and reduce turnovers.
"Every time I come back to @EmpowerField, I need to represent my guy's jersey." 🧡@ESanders_10 was on the 🎙️ for #PITvsDEN: pic.twitter.com/Pp2bdv2Ic5
— Denver Broncos (@Broncos) September 17, 2024
Denver Broncos NFL Preview
The Denver Broncos enter this Week 3 matchup searching for their first win of the season after a disappointing 0-2 start. Rookie quarterback Bo Nix has faced a challenging introduction to the NFL, throwing for 384 yards with zero touchdowns and four interceptions through the first two games. His struggles have been compounded by a lack of support from the running game, where the Broncos have averaged just 81.5 yards per contest. The offensive line will need to provide better protection, and the rushing attack, led by Javonte Williams, must step up to relieve some of the pressure on Nix. Defensively, the Broncos have been reasonably solid, allowing just 19.5 points and 277.5 yards per game. However, they have struggled with red-zone efficiency, converting only 14.3% of opportunities, the worst in the league. The defense, led by Alex Singleton and Jonathon Cooper, who has two sacks, will need to force turnovers and create short-field situations for the offense. For the Broncos to compete against the Buccaneers, they will need to establish a more balanced offensive attack and capitalize on any mistakes made by Tampa Bay.

Credit: USA TODAY/IMAGN
Tampa Bay Buccaneers NFL Preview
The Tampa Bay Buccaneers are off to a strong start in the 2024 NFL season with a 2-0 record, aiming for their first 3-0 start since 2005. Under the leadership of quarterback Baker Mayfield, who has thrown for 474 yards, five touchdowns, and one interception, the Buccaneers’ offense has been efficient and productive. Mayfield’s decision-making and ability to extend plays have been critical, and his connection with receivers Mike Evans and Chris Godwin has been a significant factor. Evans, in particular, has been a standout, scoring at least one touchdown in his last four Week 3 appearances at Raymond James Stadium. The Buccaneers’ ground game, led by Bucky Irving, has been solid, averaging 91 rushing yards per game. Defensively, while they have allowed 381 yards per game, the unit has shown resilience in the red zone, allowing just one touchdown against the Lions. Players like Jordan Whitehead and Zyon McCollum have made key plays, with Whitehead leading the team in tackles. The Buccaneers’ defense will need to maintain its red-zone efficiency and pressure Bo Nix into mistakes to secure another win. Tampa Bay’s ability to score early and control the tempo will be essential in this matchup.
"Zyon is him. Zyon is the real deal."
— Tampa Bay Buccaneers (@Buccaneers) September 17, 2024
🗣️: @greatyaya4 on @zyon_mccollum pic.twitter.com/LjehVXal14
Denver vs. Tampa Bay Prop Picks (AI)
Denver vs. Tampa Bay Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Broncos and Buccaneers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most fixated on the growing factor emotional bettors tend to put on coaching factors between a Broncos team going up against a possibly deflated Buccaneers team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Denver vs Tampa Bay picks, computer picks Broncos vs Buccaneers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Broncos Betting Trends
The Broncos have struggled on the road, failing to cover the spread in each of their last four Week 3 road games. They are also 0-2 against the spread (ATS) this season and have lost their last six away games against opponents on a winning streak.
Buccaneers Betting Trends
The Buccaneers have been solid ATS as home favorites, covering the spread in seven of their last eight games following a road win. They have also won each of their last 13 home games against opponents on a losing streak.
Broncos vs. Buccaneers Matchup Trends
The Buccaneers have won the first quarter in four of their last five games in Florida, while the favorites have won the first half in each of the Broncos’ last six Week 3 games. This trend suggests the Buccaneers could establish an early lead in this matchup.
Denver vs. Tampa Bay Game Info
What time does Denver vs Tampa Bay start on September 22, 2024?
Denver vs Tampa Bay starts on September 22, 2024 at 1:00 PM EST.
Where is Denver vs Tampa Bay being played?
Venue: Raymond James Stadium.
What are the opening odds for Denver vs Tampa Bay?
Spread: Tampa Bay -6.5
Moneyline: Denver +252, Tampa Bay -319
Over/Under: 39.5
What are the records for Denver vs Tampa Bay?
Denver: (0-2) | Tampa Bay: (2-0)
What is the AI best bet for Denver vs Tampa Bay?
Remi's searched hard and crunched the numbers and found the best prop bet play for this game: QB Bo Nix Under 175 Passing Yards. Prices move—always shop for the best number.
What are Denver vs Tampa Bay trending bets?
The Buccaneers have won the first quarter in four of their last five games in Florida, while the favorites have won the first half in each of the Broncos’ last six Week 3 games. This trend suggests the Buccaneers could establish an early lead in this matchup.
What are Denver trending bets?
DEN trend: The Broncos have struggled on the road, failing to cover the spread in each of their last four Week 3 road games. They are also 0-2 against the spread (ATS) this season and have lost their last six away games against opponents on a winning streak.
What are Tampa Bay trending bets?
TB trend: The Buccaneers have been solid ATS as home favorites, covering the spread in seven of their last eight games following a road win. They have also won each of their last 13 home games against opponents on a losing streak.
Where can I find AI Picks for Denver vs Tampa Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Denver vs. Tampa Bay Odds
Remi is pouring through tons of data points on each team. In fact, anytime the Denver vs Tampa Bay trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable patterns.
Denver vs Tampa Bay Opening Odds
DEN Moneyline:
+252 TB Moneyline: -319
DEN Spread: +6.5
TB Spread: -6.5
Over/Under: 39.5
Denver vs Tampa Bay Live Odds
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–
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+133
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O 44.5 (-113)
U 44.5 (-113)
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Buffalo Bills
Carolina Panthers
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–
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-500
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-7.5 (-115)
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O 46.5 (-112)
U 46.5 (-113)
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Cincinnati Bengals
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–
–
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+235
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+6.5 (-112)
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O 44 (-109)
U 44 (-115)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
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–
–
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+260
-360
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+6.5 (-110)
-6.5 (-115)
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O 50 (-115)
U 50 (-109)
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
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–
–
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+275
-385
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+7 (-113)
-7 (-113)
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O 43 (-114)
U 43 (-112)
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
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-109
-117
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+1 (-115)
-1 (-109)
|
O 41 (-115)
U 41 (-110)
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
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+295
-420
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+7 (-108)
-7 (-118)
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O 44.5 (-113)
U 44.5 (-113)
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Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
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-245
+185
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-4.5 (-115)
+4.5 (-110)
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O 47.5 (-109)
U 47.5 (-117)
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Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
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+135
-175
|
+3.5 (-118)
-3.5 (-108)
|
O 50 (-109)
U 50 (-117)
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
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–
–
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+650
-1250
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+14 (-108)
-14 (-118)
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O 47 (-113)
U 47 (-113)
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Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
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–
–
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-177
+135
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-3 (-113)
+3 (-113)
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O 45 (-112)
U 45 (-113)
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Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
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–
–
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+420
-670
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+10.5 (-114)
-10.5 (-112)
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O 48 (-113)
U 48 (-113)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Denver Broncos vs. Tampa Bay Buccaneers on September 22, 2024 at Raymond James Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
GB@ARI | ARI +7 | 54.8% | 5 | WIN |
NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
DET@CIN | DET -10 | 55.6% | 5 | WIN |
DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |