Rams vs Cardinals Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 15)

Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Rams will face the Arizona Cardinals on September 15, 2024, at State Farm Stadium. Both teams are looking to rebound from Week 1 losses, and the game is expected to be closely contested with the Cardinals slightly favored to win.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 15, 2024

Start Time: 4:05 PM EST​

Venue: State Farm Stadium​

Cardinals Record: (0-1)

Rams Record: (0-1)

OPENING ODDS

LAR Moneyline: +103

ARI Moneyline: -123

LAR Spread: +1.5

ARI Spread: -1.5

Over/Under: 49.5

LAR
Betting Trends

  • The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

ARI
Betting Trends

  • The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

MATCHUP TRENDS

  • The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

LAR vs. ARI
Best Prop Bet

  • Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards

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Los Angeles Rams vs Arizona Prediction & Odds:
Free NFL Betting Insights for 9/15/24

The Week 2 matchup between the Los Angeles Rams and the Arizona Cardinals at State Farm Stadium is set to be a closely fought contest between two NFC West rivals looking to avoid an 0-2 start. The Rams are coming off a tough overtime loss to the Detroit Lions, where they fell 26-20 despite a strong performance from quarterback Matthew Stafford. Stafford completed 34 of 49 passes for 317 yards, one touchdown, and one interception, showing he can still lead an effective passing attack. However, the Rams’ defense struggled late in the game, particularly against the run, which could be a problem against an Arizona team that also likes to establish the run early.

The Cardinals, meanwhile, dropped their opener to the Buffalo Bills, 34-28. Arizona led 17-10 at halftime but allowed 21 unanswered points in the second half. Quarterback Kyler Murray completed 21 of 31 passes for 162 yards and a touchdown while adding 57 yards on the ground. However, the Cardinals’ defense had difficulty stopping Buffalo’s offense, particularly in the second half, and will need to tighten up to prevent a similar collapse against the Rams. Both teams have potent offenses and defenses with some vulnerabilities, making this game likely to be high-scoring with both teams potentially going over 30 points.

The outcome will likely depend on which team can better control the tempo and avoid turnovers. The Rams’ defense needs to step up, especially against the run, while the Cardinals must find ways to contain Stafford and the Rams’ passing attack. Given the trends and current form of both teams, this game could be decided by a narrow margin.

Los Angeles Rams Rams NFL Preview

The Los Angeles Rams enter Week 2 against the Arizona Cardinals following a heartbreaking overtime loss to the Detroit Lions. Matthew Stafford looked sharp, throwing for 317 yards and one touchdown, but the team could not convert their strong performance into a win. Running back Kyren Williams also played a significant role, rushing for 50 yards and a touchdown. The Rams’ offense, featuring stars like Cooper Kupp, who had 14 receptions for 110 yards and a touchdown, remains potent and capable of challenging any defense. However, the Rams’ defense showed weaknesses, especially against the run, which needs to be addressed heading into their game against Arizona. The Rams will need to find a way to limit Kyler Murray’s mobility and keep James Conner from breaking off big gains. Additionally, the Rams have not covered the spread in their last five games before a division game, indicating potential issues when facing familiar opponents. To win on the road, the Rams will need a balanced attack on offense and a disciplined, focused effort on defense to prevent the Cardinals from capitalizing on mistakes. If they can manage this, they have the tools to come away with a victory in Arizona.

The Los Angeles Rams will face the Arizona Cardinals on September 15, 2024, at State Farm Stadium. Both teams are looking to rebound from Week 1 losses, and the game is expected to be closely contested with the Cardinals slightly favored to win. Los Angeles Rams vs Arizona AI Prediction: Free NFL Betting Insights for Sep 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Arizona Cardinals NFL Preview

The Arizona Cardinals come into their Week 2 matchup against the Los Angeles Rams looking to bounce back from a disappointing Week 1 loss to the Buffalo Bills. Kyler Murray showed flashes of brilliance in the opener, completing 21 of 31 passes for 162 yards, one touchdown, and no interceptions, while also rushing for 57 yards. However, the Cardinals’ defense struggled significantly, especially in the second half, allowing Buffalo to score 21 unanswered points. The defense must improve against both the run and pass, particularly in managing a Rams offense led by Matthew Stafford. Offensively, the Cardinals will need more production from their skill players, including rookie wide receiver Marvin Harrison Jr., who was quiet in Week 1 with just one reception for four yards. Running back James Conner will be crucial in maintaining offensive balance and keeping the Rams’ defense honest. If the Cardinals can establish a ground game early, it will open up opportunities for Murray to exploit the Rams’ secondary. Defensively, Arizona must focus on pressuring Stafford and forcing turnovers to shift momentum in their favor. With the advantage of playing at home, the Cardinals have a slight edge but must play a more complete game to secure a win.

Los Angeles Rams vs. Arizona Prop Picks (AI)

Remi is pouring through mountains of stats on each line. In fact, anytime the Rams and Cardinals play there’s always several intriguing angles to key in on. Not to mention games played at State Farm Stadium in Sep can often follow normal, predictable patterns.
Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards

Los Angeles Rams vs. Arizona Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over tons of data from every angle between the Rams and Cardinals and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Remi has been most focused on the trending emphasis human bettors regularly put on Arizona’s strength factors between a Rams team going up against a possibly unhealthy Cardinals team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Los Angeles Rams vs Arizona picks, computer picks Rams vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 5 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 10/20 TB@DET UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 10/20 HOU@SEA UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 10/20 TB@DET UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Rams Betting Trends

The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

Cardinals Betting Trends

The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

Rams vs. Cardinals Matchup Trends

The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

Los Angeles Rams vs. Arizona Game Info

Los Angeles Rams vs Arizona starts on September 15, 2024 at 4:05 PM EST.

Spread: Arizona -1.5
Moneyline: Los Angeles Rams +103, Arizona -123
Over/Under: 49.5

Los Angeles Rams: (0-1)  |  Arizona: (0-1)

Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards . Prices move—always shop for the best number.

The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

LAR trend: The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

ARI trend: The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Los Angeles Rams vs. Arizona Odds

AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Los Angeles Rams vs Arizona trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

Los Angeles Rams vs Arizona Opening Odds

LAR Moneyline: +103
ARI Moneyline: -123
LAR Spread: +1.5
ARI Spread: -1.5
Over/Under: 49.5

Los Angeles Rams vs Arizona Live Odds

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+242
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+229
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U 50.5 (-110)
Oct 26, 2025 1:00PM EDT
New York Giants
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10/26/25 1PM
Giants
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+287
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O 43.5 (-110)
U 43.5 (-110)
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+141
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U 47.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Rams Rams vs. Arizona Cardinals on September 15, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS