Rams vs. Cardinals
Prediction, Odds & Props
Sep 15 | NFL AI Picks

Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Rams will face the Arizona Cardinals on September 15, 2024, at State Farm Stadium. Both teams are looking to rebound from Week 1 losses, and the game is expected to be closely contested with the Cardinals slightly favored to win.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 15, 2024

Start Time: 4:05 PM EST​

Venue: State Farm Stadium​

Cardinals Record: (0-1)

Rams Record: (0-1)

OPENING ODDS

LAR Moneyline: +103

ARI Moneyline: -123

LAR Spread: +1.5

ARI Spread: -1.5

Over/Under: 49.5

LAR
Betting Trends

  • The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

ARI
Betting Trends

  • The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

MATCHUP TRENDS

  • The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

LAR vs. ARI
Best Prop Bet

  • Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards

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Los Angeles Rams vs Arizona Prediction & Odds:
Free NFL Betting Insights for 9/15/24

The Week 2 matchup between the Los Angeles Rams and the Arizona Cardinals at State Farm Stadium is set to be a closely fought contest between two NFC West rivals looking to avoid an 0-2 start. The Rams are coming off a tough overtime loss to the Detroit Lions, where they fell 26-20 despite a strong performance from quarterback Matthew Stafford. Stafford completed 34 of 49 passes for 317 yards, one touchdown, and one interception, showing he can still lead an effective passing attack. However, the Rams’ defense struggled late in the game, particularly against the run, which could be a problem against an Arizona team that also likes to establish the run early.

The Cardinals, meanwhile, dropped their opener to the Buffalo Bills, 34-28. Arizona led 17-10 at halftime but allowed 21 unanswered points in the second half. Quarterback Kyler Murray completed 21 of 31 passes for 162 yards and a touchdown while adding 57 yards on the ground. However, the Cardinals’ defense had difficulty stopping Buffalo’s offense, particularly in the second half, and will need to tighten up to prevent a similar collapse against the Rams. Both teams have potent offenses and defenses with some vulnerabilities, making this game likely to be high-scoring with both teams potentially going over 30 points.

The outcome will likely depend on which team can better control the tempo and avoid turnovers. The Rams’ defense needs to step up, especially against the run, while the Cardinals must find ways to contain Stafford and the Rams’ passing attack. Given the trends and current form of both teams, this game could be decided by a narrow margin.

Los Angeles Rams Rams NFL Preview

The Los Angeles Rams enter Week 2 against the Arizona Cardinals following a heartbreaking overtime loss to the Detroit Lions. Matthew Stafford looked sharp, throwing for 317 yards and one touchdown, but the team could not convert their strong performance into a win. Running back Kyren Williams also played a significant role, rushing for 50 yards and a touchdown. The Rams’ offense, featuring stars like Cooper Kupp, who had 14 receptions for 110 yards and a touchdown, remains potent and capable of challenging any defense. However, the Rams’ defense showed weaknesses, especially against the run, which needs to be addressed heading into their game against Arizona. The Rams will need to find a way to limit Kyler Murray’s mobility and keep James Conner from breaking off big gains. Additionally, the Rams have not covered the spread in their last five games before a division game, indicating potential issues when facing familiar opponents. To win on the road, the Rams will need a balanced attack on offense and a disciplined, focused effort on defense to prevent the Cardinals from capitalizing on mistakes. If they can manage this, they have the tools to come away with a victory in Arizona.

The Los Angeles Rams will face the Arizona Cardinals on September 15, 2024, at State Farm Stadium. Both teams are looking to rebound from Week 1 losses, and the game is expected to be closely contested with the Cardinals slightly favored to win. Los Angeles Rams vs Arizona AI Prediction: Free NFL Betting Insights for Sep 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Arizona Cardinals NFL Preview

The Arizona Cardinals come into their Week 2 matchup against the Los Angeles Rams looking to bounce back from a disappointing Week 1 loss to the Buffalo Bills. Kyler Murray showed flashes of brilliance in the opener, completing 21 of 31 passes for 162 yards, one touchdown, and no interceptions, while also rushing for 57 yards. However, the Cardinals’ defense struggled significantly, especially in the second half, allowing Buffalo to score 21 unanswered points. The defense must improve against both the run and pass, particularly in managing a Rams offense led by Matthew Stafford. Offensively, the Cardinals will need more production from their skill players, including rookie wide receiver Marvin Harrison Jr., who was quiet in Week 1 with just one reception for four yards. Running back James Conner will be crucial in maintaining offensive balance and keeping the Rams’ defense honest. If the Cardinals can establish a ground game early, it will open up opportunities for Murray to exploit the Rams’ secondary. Defensively, Arizona must focus on pressuring Stafford and forcing turnovers to shift momentum in their favor. With the advantage of playing at home, the Cardinals have a slight edge but must play a more complete game to secure a win.

Los Angeles Rams vs. Arizona Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each player. In fact, anytime the Rams and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at State Farm Stadium in Sep can often follow normal, predictable betting trends.
Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards

Los Angeles Rams vs. Arizona Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every simulation between the Rams and Cardinals and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

The Algorithm has been most fixated on the growing emphasis emotional bettors regularly put on player performance factors between a Rams team going up against a possibly strong Cardinals team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Los Angeles Rams vs Arizona picks, computer picks Rams vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Rams Betting Trends

The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

Cardinals Betting Trends

The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

Rams vs. Cardinals Matchup Trends

The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

Los Angeles Rams vs. Arizona Game Info

Los Angeles Rams vs Arizona starts on September 15, 2024 at 4:05 PM EST.

Spread: Arizona -1.5
Moneyline: Los Angeles Rams +103, Arizona -123
Over/Under: 49.5

Los Angeles Rams: (0-1)  |  Arizona: (0-1)

Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Rams vs. Arizona Cardinals matchup: Prop Bet: Kyren Williams Over 102.5 Total Rushing + Receiving Yards . Prices move—always shop for the best number.

The Rams have lost the first quarter in three of their last four games at State Farm Stadium. Conversely, the favorites have won the first half in each of the Rams’ last six games, suggesting a potential trend of slow starts for Los Angeles.

LAR trend: The Los Angeles Rams have struggled to cover the spread recently, failing to do so in each of their last five games before a division game. Additionally, they have lost four of their last five away games against opponents on a losing streak.

ARI trend: The Arizona Cardinals have been more successful in covering the spread in similar situations, winning five of their last six Week 2 home games against NFC opponents. The favorites have covered the spread in six of the last seven games played at State Farm Stadium.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Los Angeles Rams vs. Arizona Odds

AI algorithm Remi is pouring through tons of stats on each team. In fact, anytime the Los Angeles Rams vs Arizona trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable betting trends.

Los Angeles Rams vs Arizona Opening Odds

LAR Moneyline: +103
ARI Moneyline: -123
LAR Spread: +1.5
ARI Spread: -1.5
Over/Under: 49.5

Los Angeles Rams vs Arizona Live Odds

Games PTS ML SPR O/U
Sep 28, 2025 9:31AM EDT
Minnesota Vikings
Pittsburgh Steelers
9/28/25 9:31AM
Vikings
Steelers
-140
+115
-2.5 (-115)
+2.5 (-105)
O 41 (-110)
U 41 (-110)
Sep 28, 2025 1:00PM EDT
Cleveland Browns
Detroit Lions
9/28/25 1PM
Browns
Lions
+400
-550
+10 (-110)
-10 (-110)
O 44.5 (-105)
U 44.5 (-115)
Sep 28, 2025 1:00PM EDT
Los Angeles Chargers
New York Giants
9/28/25 1PM
Chargers
Giants
-285
+230
-6.5 (-105)
+6.5 (-115)
O 44 (-110)
U 44 (-110)
Sep 28, 2025 1:01PM EDT
Tennessee Titans
Houston Texans
9/28/25 1:01PM
Titans
Texans
+300
-375
+7 (-105)
-7 (-115)
O 39 (-110)
U 39 (-110)
Sep 28, 2025 1:01PM EDT
Philadelphia Eagles
Tampa Bay Buccaneers
9/28/25 1:01PM
Eagles
Buccaneers
-190
+160
-3.5 (-105)
+3.5 (-115)
O 44 (-110)
U 44 (-110)
Sep 28, 2025 1:01PM EDT
Washington Commanders
Atlanta Falcons
9/28/25 1:01PM
Commanders
Falcons
+110
-130
+2 (-110)
-2 (-110)
O 43.5 (-110)
U 43.5 (-110)
Sep 28, 2025 1:01PM EDT
New Orleans Saints
Buffalo Bills
9/28/25 1:01PM
Saints
Bills
+800
-1300
+15 (-110)
-15 (-110)
O 48 (-110)
U 48 (-110)
Sep 28, 2025 1:01PM EDT
Carolina Panthers
New England Patriots
9/28/25 1:01PM
Panthers
Patriots
+200
-250
+5.5 (-110)
-5.5 (-110)
O 43 (-110)
U 43 (-110)
Sep 28, 2025 4:06PM EDT
Jacksonville Jaguars
San Francisco 49ers
9/28/25 4:06PM
Jaguars
49ers
+150
-180
+3.5 (-115)
-3.5 (-105)
O 46.5 (-110)
U 46.5 (-110)
Sep 28, 2025 4:06PM EDT
Indianapolis Colts
Los Angeles Rams
9/28/25 4:06PM
Colts
Rams
+160
-190
+3.5 (-110)
-3.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Sep 28, 2025 4:25PM EDT
Baltimore Ravens
Kansas City Chiefs
9/28/25 4:25PM
Ravens
Chiefs
-150
+125
-2.5 (-120)
+2.5 (+100)
O 48.5 (-110)
U 48.5 (-110)
Sep 28, 2025 4:26PM EDT
Chicago Bears
Las Vegas Raiders
9/28/25 4:26PM
Bears
Raiders
+100
-120
+1 (-110)
-1 (-110)
O 48 (-110)
U 48 (-110)
Sep 28, 2025 8:21PM EDT
Green Bay Packers
Dallas Cowboys
9/28/25 8:21PM
Packers
Cowboys
-325
+250
-7 (-105)
+7 (-115)
O 47 (-110)
U 47 (-110)
Sep 29, 2025 7:15PM EDT
New York Jets
Miami Dolphins
9/29/25 7:15PM
Jets
Dolphins
+125
-150
+3 (-115)
-3 (-105)
O 44.5 (-110)
U 44.5 (-110)
Sep 29, 2025 8:15PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:15PM
Bengals
Broncos
+310
-400
+7.5 (-110)
-7.5 (-110)
O 44 (-110)
U 44 (-110)
Oct 2, 2025 8:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 8:16PM
49ers
Rams
+134
-158
+3 (-105)
-3 (-115)
O 47 (-110)
U 47 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Rams Rams vs. Arizona Cardinals on September 15, 2024 at State Farm Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS
GB@CLE GB -7 54.3% 4 LOSS
ARI@SF ARI +3 57.7% 6 WIN
KC@NYG PATRICK MAHOMES OVER 230.5 PASS YDS 54.7% 4 WIN
GB@CLE JOE FLACCO OVER 37.5 PASS ATT 56.6% 6 LOSS
MIA@BUF TYREEK HILL OVER 5.5 TOTAL RECEPTIONS 56.8% 6 LOSS
LAC@LV LAC -3 54.9% 4 WIN
TB@HOU BAKER MAYFIELD OVER 1.5 PASS TDS 54.4% 4 WIN
CHI@DET DET -6.5 54.3% 4 WIN
DEN@IND DEN -118 60.1% 10 LOSS
PHI@KC PHI -115 56.7% 6 WIN
SF@NO SF -3 58.8% 8 WIN
SEA@PIT OVER 40 54.9% 4 WIN
CAR@ARI BRYCE YOUNG INTERCEPTIONS UNDER 0.5 56.4% 6 LOSS
DEN@IND JOSH DOWNS RECEPTIONS OVER 3.5 54.7% 4 WIN
ATL@MIN BIJAN ROBINSON RUSH + REC YDS OVER 94.5 53.4% 3 WIN
WAS@GB WAS +3.5 56.5% 6 LOSS
WAS@GB JORDAN LOVE OVER 5.5 RUSH YDS 54.7% 4 WIN
MIN@CHI CALEB WILLIAMS OVER 219.5 PASS YDS 53.4% 3 LOSS
TEN@DEN DEN -8.5 55.3% 5 LOSS
SF@SEA SF -115 54.6% 4 WIN
SF@SEA KENNETH WALKER III UNDER 79.5 RUSH+REC YDS 54.6% 4 WIN
CAR@JAC TANK BIGSBY OVER 10.5 RUSH ATT 56.1% 6 LOSS
KC@LAC JUSTIN HERBERT UNDER 0.5 INT 54.1% 3 WIN
DAL@PHI GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS 54.1% 4 LOSS
KC@PHI JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS 53.90% 5 WIN
KC@PHI DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS 54.40% 6 WIN
KC@PHI PATRICK MAHOMES UNDER 68.3% PASS COMP 55.00% 8 WIN
KC@PHI JALEN HURTS LONGEST RUSH OVER 12.5 YDS 55.60% 8 WIN
BUF@KC DALTON KINCAID OVER 29.5 RECV YDS 55.10% 8 LOSS
WAS@PHI DEVONTA SMITH OVER 3.5 RECEPTIONS 55.80% 8 WIN
BUF@KC JAMES COOK ANYTIME TD 53.00% 5 WIN
LAR@PHI SAQUON BARKLEY UNDER 128 RUSH + REC YDS 53.20% 5 LOSS
BAL@BUF LAMAR JACKSON OVER 54.5 RUSH YDS 54.50% 6 LOSS
HOU@KC C.J. STROUD RUSH YDS UNDER 14.5 53.10% 5 LOSS
WAS@DET JAMESON WILLIAMS RUSH YDS OVER 1.5 53.30% 5 WIN
WAS@DET JARED GOFF PASS COMP % UNDER 72.3 54.30% 6 WIN
MIN@LAR COOPER KUPP ANYTIME TOUCHDOWN 52.60% 3 LOSS
MIN@LAR MATTHEW STAFFORD OVER 21.5 PASS COMP 54.10% 6 LOSS
WAS@TB BRIAN ROBINSON JR OVER 1.5 REC TARGETS 53.50% 5 WIN
WAS@TB BAKER MAYFIELD UNDER 33.5 PASS ATT 54.90% 6 WIN
GB@PHI JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE 54.60% 6 LOSS
LAC@HOU J.K. DOBBINS ANYTIME TD 52.80% 3 LOSS
LAC@HOU LAC -2.5 53.40% 3 LOSS
LAC@HOU JUSTIN HERBERT OVER 19.5 RUSH YDS 53.40% 5 LOSS