Chargers vs Panthers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 15)
Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Los Angeles Chargers will face the Carolina Panthers on September 15, 2024, at Bank of America Stadium in Charlotte. The Chargers come into the game with a 1-0 record, while the Panthers are looking to bounce back from a disappointing season opener loss.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 15, 2024
Start Time: 1:00 PM EST
Venue: Bank of America Stadium
Panthers Record: (0-1)
Chargers Record: (1-0)
OPENING ODDS
LAC Moneyline: -284
CAR Moneyline: +231
LAC Spread: -6.5
CAR Spread: +6.5
Over/Under: 39
LAC
Betting Trends
- The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
CAR
Betting Trends
- The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
MATCHUP TRENDS
- The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
LAC vs. CAR
Best Prop Bet
- Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions
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Los Angeles vs Carolina Prediction & Odds:
Free NFL Betting Insights for 9/15/24
On the other side, the Carolina Panthers are in a rebuilding phase, led by rookie quarterback Bryce Young. Young struggled in his debut, completing only 43.3% of his passes with two interceptions and no touchdowns. The Panthers’ offense must improve significantly to compete with a potent Chargers team. Key offensive players like wide receivers Adam Thielen and Jonathan Mingo need to step up to help Young and provide a balanced attack. The Panthers’ defense, which allowed 47 points in their first game, will have to find a way to contain Herbert and Dobbins to avoid a repeat of their Week 1 performance. The game will likely be decided by whether the Panthers can tighten up their defense and capitalize on any mistakes made by the Chargers.
consider this ur warning pic.twitter.com/orXUoTrXJ9
— Los Angeles Chargers (@chargers) September 5, 2024
Los Angeles Chargers NFL Preview
The Los Angeles Chargers come into Week 2 with confidence after a successful Week 1 showing and will look to continue their winning start under new head coach Jim Harbaugh. Quarterback Justin Herbert, who has consistently performed well in September, will spearhead the offense. Herbert has thrown three or more touchdowns in three of his last four road games in September and has completed 21+ passes in each of the Chargers’ last 11 games against NFC opponents. The Chargers will likely lean on their aerial attack against a shaky Panthers secondary, with receivers like Joshua Palmer and rookie Ladd McConkey expected to play key roles. Running back J.K. Dobbins, who leads the NFL in yards per carry (13.5) this season, will also be pivotal for the Chargers. His ability to break through defenses and make explosive plays in both rushing and receiving will add another layer to the Chargers’ offensive game plan. On defense, the Chargers will rely on stars like Joey Bosa to pressure Bryce Young and disrupt the Panthers’ offense. If the Chargers can force Young into making mistakes, they will likely capitalize on those opportunities. With a strong defense and an offense firing on all cylinders, the Chargers are well-positioned to secure a win on the road against a struggling Panthers team.
Credit: USA TODAY/IMAGN
Carolina Panthers NFL Preview
The Carolina Panthers enter Week 2 with a sense of urgency, looking to avoid an 0-2 start for the third straight season. Led by rookie quarterback Bryce Young, the Panthers’ offense struggled mightily in their opener, and they will need a more efficient performance against a solid Chargers defense. Young’s Week 1 struggles included a completion rate of just 43.3% and two interceptions. For Carolina to have a fighting chance, Young must show more composure and accuracy in the pocket. The Panthers will look to involve their running game more prominently, with running back Chuba Hubbard having recorded 57+ rushing yards in each of his last five games as an underdog following a road loss. Additionally, wide receivers like Adam Thielen and Jonathan Mingo need to help stretch the field and create opportunities. Defensively, Carolina has major areas of concern after allowing 47 points and 379 yards in their first game. Key defensive players, such as Shaq Thompson and Eku Leota, will need to step up, especially against a high-powered Chargers offense. Injuries to key players, like defensive end Derrick Brown, could further complicate matters for a defense that already struggles to get off the field. If the Panthers are to pull off an upset, they must limit big plays from Herbert and maintain better discipline on third downs. Special teams could also be a factor, as the Panthers currently lead the NFL in kickoff return yards per game, which might help them secure better field position against the Chargers.
consider this ur warning pic.twitter.com/orXUoTrXJ9
— Los Angeles Chargers (@chargers) September 5, 2024
Los Angeles vs. Carolina Prop Picks (AI)
Los Angeles vs. Carolina Prediction (AI)
Remi, our AI sports wizard, has been pouring over tons of data from every simulation between the Chargers and Panthers and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most fixated on the growing emphasis human bettors often put on Los Angeles’s strength factors between a Chargers team going up against a possibly deflated Panthers team. We’ve found the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Los Angeles vs Carolina picks, computer picks Chargers vs Panthers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 5 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 4 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 1 |
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| NFL | 10/20 | HOU@SEA | UNLOCK THIS PICK | 0 |
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| NFL | 10/20 | TB@DET | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Chargers Betting Trends
The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
Panthers Betting Trends
The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
Chargers vs. Panthers Matchup Trends
The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
Los Angeles vs. Carolina Game Info
What time does Los Angeles vs Carolina start on September 15, 2024?
Los Angeles vs Carolina starts on September 15, 2024 at 1:00 PM EST.
Where is Los Angeles vs Carolina being played?
Venue: Bank of America Stadium.
What are the opening odds for Los Angeles vs Carolina?
Spread: Carolina +6.5
Moneyline: Los Angeles -284, Carolina +231
Over/Under: 39
What are the records for Los Angeles vs Carolina?
Los Angeles: (1-0) | Carolina: (0-1)
What is the AI best bet for Los Angeles vs Carolina?
Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions. Prices move—always shop for the best number.
What are Los Angeles vs Carolina trending bets?
The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
What are Los Angeles trending bets?
LAC trend: The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
What are Carolina trending bets?
CAR trend: The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
Where can I find AI Picks for Los Angeles vs Carolina?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Los Angeles vs. Carolina Odds
AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Los Angeles vs Carolina trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.
Los Angeles vs Carolina Opening Odds
LAC Moneyline:
-284 CAR Moneyline: +231
LAC Spread: -6.5
CAR Spread: +6.5
Over/Under: 39
Los Angeles vs Carolina Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
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–
–
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+148
-185
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+3 (+100)
-3 (-120)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
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Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
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–
–
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+270
-374
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+7 (-110)
-7 (-110)
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O 40.5 (-110)
U 40.5 (-110)
|
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Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
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–
–
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-463
+321
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-7.5 (-110)
+7.5 (-110)
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O 46 (-110)
U 46 (-110)
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Oct 26, 2025 1:00PM EDT
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Cincinnati Bengals
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Jets
Bengals
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–
–
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+242
-330
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+7 (-110)
-7 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+229
-315
|
+6.5 (+100)
-6.5 (-120)
|
O 50.5 (-110)
U 50.5 (-110)
|
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Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+287
-407
|
+7 (-110)
-7 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
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Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
-110
-116
|
+1 (-110)
-1 (-110)
|
O 41.5 (-110)
U 41.5 (-110)
|
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Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+257
-355
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-220
+169
|
-4.5 (-110)
+4.5 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+141
-181
|
+3.5 (-120)
-3.5 (+100)
|
O 50 (-110)
U 50 (-110)
|
|
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Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+682
-1442
|
+14 (-110)
-14 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-192
+148
|
-3.5 (+100)
+3.5 (-120)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+390
-599
|
+10.5 (-110)
-10.5 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Chargers vs. Carolina Panthers on September 15, 2024 at Bank of America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
| LV@WAS | LV +3 | 54.3% | 4 | LOSS |