Chargers vs. Panthers
Prediction, Odds & Props
Sep 15 | NFL AI Picks
Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Los Angeles Chargers will face the Carolina Panthers on September 15, 2024, at Bank of America Stadium in Charlotte. The Chargers come into the game with a 1-0 record, while the Panthers are looking to bounce back from a disappointing season opener loss.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 15, 2024
Start Time: 1:00 PM EST​
Venue: Bank of America Stadium​
Panthers Record: (0-1)
Chargers Record: (1-0)
OPENING ODDS
LAC Moneyline: -284
CAR Moneyline: +231
LAC Spread: -6.5
CAR Spread: +6.5
Over/Under: 39
LAC
Betting Trends
- The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
CAR
Betting Trends
- The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
MATCHUP TRENDS
- The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
LAC vs. CAR
Best Prop Bet
- Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions
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Los Angeles vs Carolina Prediction & Odds:
Free NFL Betting Insights for 9/15/24
On the other side, the Carolina Panthers are in a rebuilding phase, led by rookie quarterback Bryce Young. Young struggled in his debut, completing only 43.3% of his passes with two interceptions and no touchdowns. The Panthers’ offense must improve significantly to compete with a potent Chargers team. Key offensive players like wide receivers Adam Thielen and Jonathan Mingo need to step up to help Young and provide a balanced attack. The Panthers’ defense, which allowed 47 points in their first game, will have to find a way to contain Herbert and Dobbins to avoid a repeat of their Week 1 performance. The game will likely be decided by whether the Panthers can tighten up their defense and capitalize on any mistakes made by the Chargers.
consider this ur warning pic.twitter.com/orXUoTrXJ9
— Los Angeles Chargers (@chargers) September 5, 2024
Los Angeles Chargers NFL Preview
The Los Angeles Chargers come into Week 2 with confidence after a successful Week 1 showing and will look to continue their winning start under new head coach Jim Harbaugh. Quarterback Justin Herbert, who has consistently performed well in September, will spearhead the offense. Herbert has thrown three or more touchdowns in three of his last four road games in September and has completed 21+ passes in each of the Chargers’ last 11 games against NFC opponents. The Chargers will likely lean on their aerial attack against a shaky Panthers secondary, with receivers like Joshua Palmer and rookie Ladd McConkey expected to play key roles. Running back J.K. Dobbins, who leads the NFL in yards per carry (13.5) this season, will also be pivotal for the Chargers. His ability to break through defenses and make explosive plays in both rushing and receiving will add another layer to the Chargers’ offensive game plan. On defense, the Chargers will rely on stars like Joey Bosa to pressure Bryce Young and disrupt the Panthers’ offense. If the Chargers can force Young into making mistakes, they will likely capitalize on those opportunities. With a strong defense and an offense firing on all cylinders, the Chargers are well-positioned to secure a win on the road against a struggling Panthers team.

Credit: USA TODAY/IMAGN
Carolina Panthers NFL Preview
The Carolina Panthers enter Week 2 with a sense of urgency, looking to avoid an 0-2 start for the third straight season. Led by rookie quarterback Bryce Young, the Panthers’ offense struggled mightily in their opener, and they will need a more efficient performance against a solid Chargers defense. Young’s Week 1 struggles included a completion rate of just 43.3% and two interceptions. For Carolina to have a fighting chance, Young must show more composure and accuracy in the pocket. The Panthers will look to involve their running game more prominently, with running back Chuba Hubbard having recorded 57+ rushing yards in each of his last five games as an underdog following a road loss. Additionally, wide receivers like Adam Thielen and Jonathan Mingo need to help stretch the field and create opportunities. Defensively, Carolina has major areas of concern after allowing 47 points and 379 yards in their first game. Key defensive players, such as Shaq Thompson and Eku Leota, will need to step up, especially against a high-powered Chargers offense. Injuries to key players, like defensive end Derrick Brown, could further complicate matters for a defense that already struggles to get off the field. If the Panthers are to pull off an upset, they must limit big plays from Herbert and maintain better discipline on third downs. Special teams could also be a factor, as the Panthers currently lead the NFL in kickoff return yards per game, which might help them secure better field position against the Chargers.
consider this ur warning pic.twitter.com/orXUoTrXJ9
— Los Angeles Chargers (@chargers) September 5, 2024
Los Angeles vs. Carolina Prop Picks (AI)
Los Angeles vs. Carolina Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Chargers and Panthers and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Interestingly enough, the data has been most watching on the unproportionally assigned factor emotional bettors often put on coaching factors between a Chargers team going up against a possibly strong Panthers team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Los Angeles vs Carolina picks, computer picks Chargers vs Panthers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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NFL | 9/28 | LAC@NYG | UNLOCK THIS PICK | 7 |
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NFL | 9/28 | TEN@HOU | UNLOCK THIS PICK | 7 |
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NFL | 9/28 | CAR@NE | UNLOCK THIS PICK | 6 |
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NFL | 9/28 | BAL@KC | UNLOCK THIS PICK | 6 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 5 |
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NFL | 9/28 | WAS@ATL | UNLOCK THIS PICK | 4 |
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NFL | 9/28 | NO@BUF | UNLOCK THIS PICK | 3 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 2 |
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NFL | 9/28 | CHI@LV | GET FREE PICK NOW | 2 | – | |
NFL | 9/28 | PHI@TB | UNLOCK THIS PICK | 10 |
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NFL | 9/28 | BAL@KC | UNLOCK THIS PICK | 0 |
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NFL | 9/28 | IND@LAR | UNLOCK THIS PICK | 1 |
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NFL | 9/28 | CAR@NE | UNLOCK THIS PICK | 0 |
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NFL | 9/28 | GB@DAL | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Chargers Betting Trends
The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
Panthers Betting Trends
The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
Chargers vs. Panthers Matchup Trends
The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
Los Angeles vs. Carolina Game Info
What time does Los Angeles vs Carolina start on September 15, 2024?
Los Angeles vs Carolina starts on September 15, 2024 at 1:00 PM EST.
Where is Los Angeles vs Carolina being played?
Venue: Bank of America Stadium.
What are the opening odds for Los Angeles vs Carolina?
Spread: Carolina +6.5
Moneyline: Los Angeles -284, Carolina +231
Over/Under: 39
What are the records for Los Angeles vs Carolina?
Los Angeles: (1-0) Â |Â Carolina: (0-1)
What is the AI best bet for Los Angeles vs Carolina?
Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions. Prices move—always shop for the best number.
What are Los Angeles vs Carolina trending bets?
The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.
What are Los Angeles trending bets?
LAC trend: The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.
What are Carolina trending bets?
CAR trend: The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.
Where can I find AI Picks for Los Angeles vs Carolina?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Los Angeles vs. Carolina Odds
AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the Los Angeles vs Carolina trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.
Los Angeles vs Carolina Opening Odds
LAC Moneyline:
-284 CAR Moneyline: +231
LAC Spread: -6.5
CAR Spread: +6.5
Over/Under: 39
Los Angeles vs Carolina Live Odds
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–
–
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+130
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O 45.5 (-105)
U 45.5 (-115)
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+380
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O 44.5 (-105)
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+150
-180
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+3 (+100)
-3 (-120)
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O 47.5 (-105)
U 47.5 (-115)
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-205
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-4.5 (+100)
+4.5 (-120)
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O 37.5 (-110)
U 37.5 (-110)
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Colts
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–
–
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+240
-298
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+6.5 (-110)
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O 48.5 (-105)
U 48.5 (-115)
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Oct 5, 2025 12:01PM EDT
New York Giants
New Orleans Saints
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Giants
Saints
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–
–
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-135
+114
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-2.5 (-110)
+2.5 (-110)
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O 41.5 (-110)
U 41.5 (-110)
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Oct 5, 2025 12:01PM EDT
Houston Texans
Baltimore Ravens
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Ravens
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–
–
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+330
-420
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+7.5 (-110)
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O 44.5 (-115)
U 44.5 (-105)
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Oct 5, 2025 12:01PM EDT
Denver Broncos
Philadelphia Eagles
10/5/25 12:01PM
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Eagles
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–
–
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+190
-230
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+4.5 (+100)
-4.5 (-120)
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O 43.5 (-115)
U 43.5 (-105)
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Oct 5, 2025 12:01PM EDT
Miami Dolphins
Carolina Panthers
10/5/25 12:01PM
Dolphins
Panthers
|
–
–
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-125
+105
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-1.5 (-110)
+1.5 (-110)
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O 46.5 (-110)
U 46.5 (-110)
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Dallas Cowboys
New York Jets
10/5/25 1PM
Cowboys
Jets
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–
–
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-135
+114
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-2.5 (-110)
+2.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 5, 2025 3:06PM EDT
Tampa Bay Buccaneers
Seattle Seahawks
10/5/25 3:06PM
Buccaneers
Seahawks
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–
–
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+120
-142
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+2.5 (+100)
-2.5 (-120)
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O 45.5 (-105)
U 45.5 (-115)
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Oct 5, 2025 3:06PM EDT
Tennessee Titans
Arizona Cardinals
10/5/25 3:06PM
Titans
Cardinals
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–
–
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+380
-500
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+8.5 (-105)
-8.5 (-115)
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O 40.5 (-110)
U 40.5 (-110)
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Oct 5, 2025 3:26PM EDT
Washington Commanders
Los Angeles Chargers
10/5/25 3:26PM
Commanders
Chargers
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–
–
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+140
-166
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+3 (-110)
-3 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 5, 2025 3:26PM EDT
Detroit Lions
Cincinnati Bengals
10/5/25 3:26PM
Lions
Bengals
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–
–
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-440
+340
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-8.5 (-110)
+8.5 (-110)
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O 48.5 (-110)
U 48.5 (-110)
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Oct 5, 2025 7:21PM EDT
New England Patriots
Buffalo Bills
10/5/25 7:21PM
Patriots
Bills
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–
–
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+360
-470
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+8.5 (-110)
-8.5 (-110)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 6, 2025 7:16PM EDT
Kansas City Chiefs
Jacksonville Jaguars
10/6/25 7:16PM
Chiefs
Jaguars
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–
–
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-166
+140
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-3 (-115)
+3 (-105)
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O 45.5 (-110)
U 45.5 (-110)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Chargers vs. Carolina Panthers on September 15, 2024 at Bank of America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
PIT@NE | PIT -116 | 60.1% | 6 | WIN |
ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |
LV@WAS | LV +3 | 54.3% | 4 | LOSS |
GB@CLE | GB -7 | 54.3% | 4 | LOSS |
ARI@SF | ARI +3 | 57.7% | 6 | WIN |
KC@NYG | PATRICK MAHOMES OVER 230.5 PASS YDS | 54.7% | 4 | WIN |
GB@CLE | JOE FLACCO OVER 37.5 PASS ATT | 56.6% | 6 | LOSS |
MIA@BUF | TYREEK HILL OVER 5.5 TOTAL RECEPTIONS | 56.8% | 6 | LOSS |
LAC@LV | LAC -3 | 54.9% | 4 | WIN |
TB@HOU | BAKER MAYFIELD OVER 1.5 PASS TDS | 54.4% | 4 | WIN |
CHI@DET | DET -6.5 | 54.3% | 4 | WIN |
DEN@IND | DEN -118 | 60.1% | 10 | LOSS |
PHI@KC | PHI -115 | 56.7% | 6 | WIN |
SF@NO | SF -3 | 58.8% | 8 | WIN |
SEA@PIT | OVER 40 | 54.9% | 4 | WIN |
CAR@ARI | BRYCE YOUNG INTERCEPTIONS UNDER 0.5 | 56.4% | 6 | LOSS |
DEN@IND | JOSH DOWNS RECEPTIONS OVER 3.5 | 54.7% | 4 | WIN |
ATL@MIN | BIJAN ROBINSON RUSH + REC YDS OVER 94.5 | 53.4% | 3 | WIN |
WAS@GB | WAS +3.5 | 56.5% | 6 | LOSS |
WAS@GB | JORDAN LOVE OVER 5.5 RUSH YDS | 54.7% | 4 | WIN |
MIN@CHI | CALEB WILLIAMS OVER 219.5 PASS YDS | 53.4% | 3 | LOSS |
TEN@DEN | DEN -8.5 | 55.3% | 5 | LOSS |
SF@SEA | SF -115 | 54.6% | 4 | WIN |
SF@SEA | KENNETH WALKER III UNDER 79.5 RUSH+REC YDS | 54.6% | 4 | WIN |
CAR@JAC | TANK BIGSBY OVER 10.5 RUSH ATT | 56.1% | 6 | LOSS |
KC@LAC | JUSTIN HERBERT UNDER 0.5 INT | 54.1% | 3 | WIN |
DAL@PHI | GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS | 54.1% | 4 | LOSS |
KC@PHI | JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS | 53.90% | 5 | WIN |
KC@PHI | DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS | 54.40% | 6 | WIN |
KC@PHI | PATRICK MAHOMES UNDER 68.3% PASS COMP | 55.00% | 8 | WIN |
KC@PHI | JALEN HURTS LONGEST RUSH OVER 12.5 YDS | 55.60% | 8 | WIN |
BUF@KC | DALTON KINCAID OVER 29.5 RECV YDS | 55.10% | 8 | LOSS |
WAS@PHI | DEVONTA SMITH OVER 3.5 RECEPTIONS | 55.80% | 8 | WIN |
BUF@KC | JAMES COOK ANYTIME TD | 53.00% | 5 | WIN |
LAR@PHI | SAQUON BARKLEY UNDER 128 RUSH + REC YDS | 53.20% | 5 | LOSS |
BAL@BUF | LAMAR JACKSON OVER 54.5 RUSH YDS | 54.50% | 6 | LOSS |
HOU@KC | C.J. STROUD RUSH YDS UNDER 14.5 | 53.10% | 5 | LOSS |
WAS@DET | JAMESON WILLIAMS RUSH YDS OVER 1.5 | 53.30% | 5 | WIN |
WAS@DET | JARED GOFF PASS COMP % UNDER 72.3 | 54.30% | 6 | WIN |
MIN@LAR | COOPER KUPP ANYTIME TOUCHDOWN | 52.60% | 3 | LOSS |
MIN@LAR | MATTHEW STAFFORD OVER 21.5 PASS COMP | 54.10% | 6 | LOSS |
WAS@TB | BRIAN ROBINSON JR OVER 1.5 REC TARGETS | 53.50% | 5 | WIN |
WAS@TB | BAKER MAYFIELD UNDER 33.5 PASS ATT | 54.90% | 6 | WIN |
GB@PHI | JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE | 54.60% | 6 | LOSS |
LAC@HOU | J.K. DOBBINS ANYTIME TD | 52.80% | 3 | LOSS |
LAC@HOU | LAC -2.5 | 53.40% | 3 | LOSS |
LAC@HOU | JUSTIN HERBERT OVER 19.5 RUSH YDS | 53.40% | 5 | LOSS |