Chargers vs. Panthers
Prediction, Odds & Props
Sep 15 | NFL AI Picks

Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Chargers will face the Carolina Panthers on September 15, 2024, at Bank of America Stadium in Charlotte. The Chargers come into the game with a 1-0 record, while the Panthers are looking to bounce back from a disappointing season opener loss.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 15, 2024

Start Time: 1:00 PM EST​

Venue: Bank of America Stadium​

Panthers Record: (0-1)

Chargers Record: (1-0)

OPENING ODDS

LAC Moneyline: -284

CAR Moneyline: +231

LAC Spread: -6.5

CAR Spread: +6.5

Over/Under: 39

LAC
Betting Trends

  • The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.

CAR
Betting Trends

  • The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.

MATCHUP TRENDS

  • The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.

LAC vs. CAR
Best Prop Bet

  • Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions

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Los Angeles vs Carolina Prediction & Odds:
Free NFL Betting Insights for 9/15/24

The Los Angeles Chargers and Carolina Panthers will clash in Week 2 of the NFL season at Bank of America Stadium. The Chargers enter the game following a strong opening-week performance and aim to continue their momentum under head coach Jim Harbaugh. Quarterback Justin Herbert, who has been prolific in September games, will lead the offense. Herbert has thrown for 229+ yards in 11 of his last 12 September games and is expected to continue his aggressive passing style against a Panthers defense that allowed 379 yards in their opener. Key contributors for the Chargers will include rookie wide receiver Ladd McConkey, who appears to be emerging as a reliable target, and running back J.K. Dobbins, who leads the team in rushing yards and is favored to score in this game.

On the other side, the Carolina Panthers are in a rebuilding phase, led by rookie quarterback Bryce Young. Young struggled in his debut, completing only 43.3% of his passes with two interceptions and no touchdowns. The Panthers’ offense must improve significantly to compete with a potent Chargers team. Key offensive players like wide receivers Adam Thielen and Jonathan Mingo need to step up to help Young and provide a balanced attack. The Panthers’ defense, which allowed 47 points in their first game, will have to find a way to contain Herbert and Dobbins to avoid a repeat of their Week 1 performance. The game will likely be decided by whether the Panthers can tighten up their defense and capitalize on any mistakes made by the Chargers.

Los Angeles Chargers NFL Preview

The Los Angeles Chargers come into Week 2 with confidence after a successful Week 1 showing and will look to continue their winning start under new head coach Jim Harbaugh. Quarterback Justin Herbert, who has consistently performed well in September, will spearhead the offense. Herbert has thrown three or more touchdowns in three of his last four road games in September and has completed 21+ passes in each of the Chargers’ last 11 games against NFC opponents. The Chargers will likely lean on their aerial attack against a shaky Panthers secondary, with receivers like Joshua Palmer and rookie Ladd McConkey expected to play key roles. Running back J.K. Dobbins, who leads the NFL in yards per carry (13.5) this season, will also be pivotal for the Chargers. His ability to break through defenses and make explosive plays in both rushing and receiving will add another layer to the Chargers’ offensive game plan. On defense, the Chargers will rely on stars like Joey Bosa to pressure Bryce Young and disrupt the Panthers’ offense. If the Chargers can force Young into making mistakes, they will likely capitalize on those opportunities. With a strong defense and an offense firing on all cylinders, the Chargers are well-positioned to secure a win on the road against a struggling Panthers team.

The Los Angeles Chargers will face the Carolina Panthers on September 15, 2024, at Bank of America Stadium in Charlotte. The Chargers come into the game with a 1-0 record, while the Panthers are looking to bounce back from a disappointing season opener loss. Los Angeles vs Carolina AI Prediction: Free NFL Betting Insights for Sep 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Carolina Panthers NFL Preview

The Carolina Panthers enter Week 2 with a sense of urgency, looking to avoid an 0-2 start for the third straight season. Led by rookie quarterback Bryce Young, the Panthers’ offense struggled mightily in their opener, and they will need a more efficient performance against a solid Chargers defense. Young’s Week 1 struggles included a completion rate of just 43.3% and two interceptions. For Carolina to have a fighting chance, Young must show more composure and accuracy in the pocket. The Panthers will look to involve their running game more prominently, with running back Chuba Hubbard having recorded 57+ rushing yards in each of his last five games as an underdog following a road loss. Additionally, wide receivers like Adam Thielen and Jonathan Mingo need to help stretch the field and create opportunities. Defensively, Carolina has major areas of concern after allowing 47 points and 379 yards in their first game. Key defensive players, such as Shaq Thompson and Eku Leota, will need to step up, especially against a high-powered Chargers offense. Injuries to key players, like defensive end Derrick Brown, could further complicate matters for a defense that already struggles to get off the field. If the Panthers are to pull off an upset, they must limit big plays from Herbert and maintain better discipline on third downs. Special teams could also be a factor, as the Panthers currently lead the NFL in kickoff return yards per game, which might help them secure better field position against the Chargers.

Los Angeles vs. Carolina Prop Picks (AI)

Remi is pouring through loads of stats on each line. In fact, anytime the Chargers and Panthers play there’s always several intriguing angles to key in on. Not to mention games played at Bank of America Stadium in Sep can often follow normal, predictable betting trends.
Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions

Los Angeles vs. Carolina Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Chargers and Panthers and using recursive machine learning and impressive AI to examine the data to a single cover probability.

Interestingly enough, the data has been most watching on the unproportionally assigned factor emotional bettors often put on coaching factors between a Chargers team going up against a possibly strong Panthers team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI Los Angeles vs Carolina picks, computer picks Chargers vs Panthers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 9/28 LAC@NYG UNLOCK THIS PICK 7 VAULT v3 Locked VAULT v3
NFL 9/28 TEN@HOU UNLOCK THIS PICK 7 VAULT v3 Locked VAULT v3
NFL 9/28 CAR@NE UNLOCK THIS PICK 6 VAULT v3 Locked VAULT v3
NFL 9/28 BAL@KC UNLOCK THIS PICK 6 VAULT v2 Locked VAULT v2
NFL 9/28 GB@DAL UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
NFL 9/28 WAS@ATL UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 9/28 NO@BUF UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
NFL 9/28 GB@DAL UNLOCK THIS PICK 2 INTEL Locked INTEL
NFL 9/28 CHI@LV GET FREE PICK NOW 2
NFL 9/28 PHI@TB UNLOCK THIS PICK 10 INTEL Locked INTEL
NFL 9/28 BAL@KC UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 9/28 IND@LAR UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 9/28 CAR@NE UNLOCK THIS PICK 0 INTEL Locked INTEL
NFL 9/28 GB@DAL UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Chargers Betting Trends

The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.

Panthers Betting Trends

The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.

Chargers vs. Panthers Matchup Trends

The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.

Los Angeles vs. Carolina Game Info

Los Angeles vs Carolina starts on September 15, 2024 at 1:00 PM EST.

Venue: Bank of America Stadium.

Spread: Carolina +6.5
Moneyline: Los Angeles -284, Carolina +231
Over/Under: 39

Los Angeles: (1-0)  |  Carolina: (0-1)

Remi searched hard and crunched the numbers and found a prop bet for the Los Angeles Chargers vs Carolina Panthers matchup: Prop Bet: QB Justin Herbert Over 18.5 passing completions. Prices move—always shop for the best number.

The Panthers have lost nine of their last 10 Sunday games and have not covered the spread in their last four home openers as underdogs. The Chargers, conversely, have covered in six of their last seven games when playing as favorites on the East Coast, showcasing a trend that could influence bettors.

LAC trend: The Los Angeles Chargers have been strong against the spread (ATS) recently, covering in six of their last seven games played as favorites on the East Coast. The Chargers are 1-0 ATS this season after covering the spread in Week 1.

CAR trend: The Carolina Panthers have struggled against the spread, failing to cover in their last four home openers as underdogs. Overall, they are 0-1 ATS this season and 2-10 ATS in their last 12 games as underdogs of six or more points.

See our latest NFL picks and odds pages for 2024 to compare prices before you bet.

Los Angeles vs. Carolina Odds

AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the Los Angeles vs Carolina trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.

Los Angeles vs Carolina Opening Odds

LAC Moneyline: -284
CAR Moneyline: +231
LAC Spread: -6.5
CAR Spread: +6.5
Over/Under: 39

Los Angeles vs Carolina Live Odds

Games PTS ML SPR O/U
Sep 29, 2025 7:16PM EDT
New York Jets
Miami Dolphins
9/29/25 7:16PM
Jets
Dolphins
+130
-155
+2.5 (-102)
-2.5 (-118)
O 45.5 (-105)
U 45.5 (-115)
Sep 29, 2025 8:16PM EDT
Cincinnati Bengals
Denver Broncos
9/29/25 8:16PM
Bengals
Broncos
+380
-500
+7.5 (-110)
-7.5 (-110)
O 44.5 (-105)
U 44.5 (-115)
Oct 2, 2025 7:16PM EDT
San Francisco 49ers
Los Angeles Rams
10/2/25 7:16PM
49ers
Rams
+150
-180
+3 (+100)
-3 (-120)
O 47.5 (-105)
U 47.5 (-115)
Oct 5, 2025 8:31AM EDT
Minnesota Vikings
Cleveland Browns
10/5/25 8:31AM
Vikings
Browns
-205
+170
-4.5 (+100)
+4.5 (-120)
O 37.5 (-110)
U 37.5 (-110)
Oct 5, 2025 12:01PM EDT
Las Vegas Raiders
Indianapolis Colts
10/5/25 12:01PM
Raiders
Colts
+240
-298
+6.5 (-110)
-6.5 (-110)
O 48.5 (-105)
U 48.5 (-115)
Oct 5, 2025 12:01PM EDT
New York Giants
New Orleans Saints
10/5/25 12:01PM
Giants
Saints
-135
+114
-2.5 (-110)
+2.5 (-110)
O 41.5 (-110)
U 41.5 (-110)
Oct 5, 2025 12:01PM EDT
Houston Texans
Baltimore Ravens
10/5/25 12:01PM
Texans
Ravens
+330
-420
+7.5 (-110)
-7.5 (-110)
O 44.5 (-115)
U 44.5 (-105)
Oct 5, 2025 12:01PM EDT
Denver Broncos
Philadelphia Eagles
10/5/25 12:01PM
Broncos
Eagles
+190
-230
+4.5 (+100)
-4.5 (-120)
O 43.5 (-115)
U 43.5 (-105)
Oct 5, 2025 12:01PM EDT
Miami Dolphins
Carolina Panthers
10/5/25 12:01PM
Dolphins
Panthers
-125
+105
-1.5 (-110)
+1.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 5, 2025 1:00PM EDT
Dallas Cowboys
New York Jets
10/5/25 1PM
Cowboys
Jets
-135
+114
-2.5 (-110)
+2.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 5, 2025 3:06PM EDT
Tampa Bay Buccaneers
Seattle Seahawks
10/5/25 3:06PM
Buccaneers
Seahawks
+120
-142
+2.5 (+100)
-2.5 (-120)
O 45.5 (-105)
U 45.5 (-115)
Oct 5, 2025 3:06PM EDT
Tennessee Titans
Arizona Cardinals
10/5/25 3:06PM
Titans
Cardinals
+380
-500
+8.5 (-105)
-8.5 (-115)
O 40.5 (-110)
U 40.5 (-110)
Oct 5, 2025 3:26PM EDT
Washington Commanders
Los Angeles Chargers
10/5/25 3:26PM
Commanders
Chargers
+140
-166
+3 (-110)
-3 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 5, 2025 3:26PM EDT
Detroit Lions
Cincinnati Bengals
10/5/25 3:26PM
Lions
Bengals
-440
+340
-8.5 (-110)
+8.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Oct 5, 2025 7:21PM EDT
New England Patriots
Buffalo Bills
10/5/25 7:21PM
Patriots
Bills
+360
-470
+8.5 (-110)
-8.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 6, 2025 7:16PM EDT
Kansas City Chiefs
Jacksonville Jaguars
10/6/25 7:16PM
Chiefs
Jaguars
-166
+140
-3 (-115)
+3 (-105)
O 45.5 (-110)
U 45.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Chargers vs. Carolina Panthers on September 15, 2024 at Bank of America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS
GB@CLE GB -7 54.3% 4 LOSS
ARI@SF ARI +3 57.7% 6 WIN
KC@NYG PATRICK MAHOMES OVER 230.5 PASS YDS 54.7% 4 WIN
GB@CLE JOE FLACCO OVER 37.5 PASS ATT 56.6% 6 LOSS
MIA@BUF TYREEK HILL OVER 5.5 TOTAL RECEPTIONS 56.8% 6 LOSS
LAC@LV LAC -3 54.9% 4 WIN
TB@HOU BAKER MAYFIELD OVER 1.5 PASS TDS 54.4% 4 WIN
CHI@DET DET -6.5 54.3% 4 WIN
DEN@IND DEN -118 60.1% 10 LOSS
PHI@KC PHI -115 56.7% 6 WIN
SF@NO SF -3 58.8% 8 WIN
SEA@PIT OVER 40 54.9% 4 WIN
CAR@ARI BRYCE YOUNG INTERCEPTIONS UNDER 0.5 56.4% 6 LOSS
DEN@IND JOSH DOWNS RECEPTIONS OVER 3.5 54.7% 4 WIN
ATL@MIN BIJAN ROBINSON RUSH + REC YDS OVER 94.5 53.4% 3 WIN
WAS@GB WAS +3.5 56.5% 6 LOSS
WAS@GB JORDAN LOVE OVER 5.5 RUSH YDS 54.7% 4 WIN
MIN@CHI CALEB WILLIAMS OVER 219.5 PASS YDS 53.4% 3 LOSS
TEN@DEN DEN -8.5 55.3% 5 LOSS
SF@SEA SF -115 54.6% 4 WIN
SF@SEA KENNETH WALKER III UNDER 79.5 RUSH+REC YDS 54.6% 4 WIN
CAR@JAC TANK BIGSBY OVER 10.5 RUSH ATT 56.1% 6 LOSS
KC@LAC JUSTIN HERBERT UNDER 0.5 INT 54.1% 3 WIN
DAL@PHI GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS 54.1% 4 LOSS
KC@PHI JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS 53.90% 5 WIN
KC@PHI DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS 54.40% 6 WIN
KC@PHI PATRICK MAHOMES UNDER 68.3% PASS COMP 55.00% 8 WIN
KC@PHI JALEN HURTS LONGEST RUSH OVER 12.5 YDS 55.60% 8 WIN
BUF@KC DALTON KINCAID OVER 29.5 RECV YDS 55.10% 8 LOSS
WAS@PHI DEVONTA SMITH OVER 3.5 RECEPTIONS 55.80% 8 WIN
BUF@KC JAMES COOK ANYTIME TD 53.00% 5 WIN
LAR@PHI SAQUON BARKLEY UNDER 128 RUSH + REC YDS 53.20% 5 LOSS
BAL@BUF LAMAR JACKSON OVER 54.5 RUSH YDS 54.50% 6 LOSS
HOU@KC C.J. STROUD RUSH YDS UNDER 14.5 53.10% 5 LOSS
WAS@DET JAMESON WILLIAMS RUSH YDS OVER 1.5 53.30% 5 WIN
WAS@DET JARED GOFF PASS COMP % UNDER 72.3 54.30% 6 WIN
MIN@LAR COOPER KUPP ANYTIME TOUCHDOWN 52.60% 3 LOSS
MIN@LAR MATTHEW STAFFORD OVER 21.5 PASS COMP 54.10% 6 LOSS
WAS@TB BRIAN ROBINSON JR OVER 1.5 REC TARGETS 53.50% 5 WIN
WAS@TB BAKER MAYFIELD UNDER 33.5 PASS ATT 54.90% 6 WIN
GB@PHI JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE 54.60% 6 LOSS
LAC@HOU J.K. DOBBINS ANYTIME TD 52.80% 3 LOSS
LAC@HOU LAC -2.5 53.40% 3 LOSS
LAC@HOU JUSTIN HERBERT OVER 19.5 RUSH YDS 53.40% 5 LOSS