Colts vs Packers Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 15)
Updated: 2024-09-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indianapolis Colts will take on the Green Bay Packers at Lambeau Field on September 15, 2024, in a Week 2 NFL matchup. Both teams are looking for their first win of the season, with the Colts entering the game as 3.5-point favorites due to the Packers’ key injuries.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 15, 2024
Start Time: 1:00 PM EST
Venue: Lambeau Field
Packers Record: (0-1)
Colts Record: (0-1)
OPENING ODDS
IND Moneyline: -175
GB Moneyline: +145
IND Spread: -3
GB Spread: +3.0
Over/Under: 41
IND
Betting Trends
- The Indianapolis Colts have performed well against the spread (ATS) recently, especially against NFC North opponents, with an 8-0 ATS record in their last eight matchups. However, they are 1-6 ATS in the third quarter of their last seven road games, indicating potential mid-game struggles.
GB
Betting Trends
- The Green Bay Packers have a solid ATS record in the third quarter, going 13-6 in their last 19 games. However, they have struggled overall, particularly with injuries impacting their lineup. The Packers are 9-2 to the over with their team total in their last 11 games, showing a trend toward high-scoring games.
MATCHUP TRENDS
- The total points line is set at a relatively low 40.5, with a 55% chance of going over. Both teams have shown tendencies to cover the spread, but with Green Bay’s injuries, especially the absence of quarterback Jordan Love, the Colts have a 59% win probability according to simulations.
IND vs. GB
Best Prop Bet
- Remi searched hard and crunched the numbers and found a prop bet for the Indianapolis Colts vs Green Bay Packers matchup: Anthony Richardson Anytime Touchdown Scorer
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Indianapolis vs Green Bay Prediction & Odds:
Free NFL Betting Insights for 9/15/24
Wednesday's practice report for #INDvsGB: pic.twitter.com/HoJK4L4qJZ
— Indianapolis Colts (@Colts) September 11, 2024
Indianapolis Colts NFL Preview
The Indianapolis Colts are looking to capitalize on a favorable matchup against the injury-riddled Green Bay Packers. The Colts narrowly lost to the Houston Texans in Week 1, but rookie quarterback Anthony Richardson showed flashes of brilliance with his dual-threat capability, passing for 212 yards and rushing for 56 yards. With the Packers missing their starting quarterback, Richardson and the Colts’ offense are in a prime position to exploit Green Bay’s defensive weaknesses, particularly against the run. Jonathan Taylor, one of the league’s top running backs, is expected to be heavily involved, and his ability to control the tempo will be crucial for Indianapolis. On the defensive side, the Colts will aim to put pressure on Packers backup quarterback Malik Willis. Led by DeForest Buckner and Julian Blackmon, who were standout performers in Week 1, the Colts’ defense will look to create turnovers and limit big plays. The Colts’ secondary must also keep a close eye on Packers’ deep threat Jayden Reed, but without Jordan Love, the Packers’ passing game is expected to be less effective. With a balanced offense and a defense capable of stifling the Packers’ attack, the Colts are well-positioned to come away with a victory at Lambeau Field and even their season record at 1-1.
Credit: USA TODAY/IMAGN
Green Bay Packers NFL Preview
The Green Bay Packers face a significant challenge in their home opener against the Indianapolis Colts. After losing their season opener to the Philadelphia Eagles in Brazil, the Packers are dealing with key injuries that could impact their performance. With quarterback Jordan Love sidelined, backup Malik Willis will need to step up and manage the game effectively. The Packers’ offense relies heavily on running back Josh Jacobs, who had 84 rushing yards in Week 1, and wide receiver Jayden Reed, who led the team with 138 receiving yards. The Packers will need both players to perform at their best to keep the Colts’ defense on its heels. Defensively, the Packers struggled in their opener, particularly against the run. The Colts’ strong offensive line and running back Jonathan Taylor pose a formidable challenge. Green Bay’s linebackers, who were caught out of position multiple times against the Eagles, must be more disciplined to contain the Colts’ rushing attack. Green Bay’s defense will also need to generate turnovers and pressure Anthony Richardson to disrupt the Colts’ rhythm. With Lambeau Field providing a hostile environment for visiting teams, the Packers will look to leverage their home advantage to secure a win, but they must overcome the challenges posed by injuries and a potent Colts offense.
Wednesday's practice report for #INDvsGB: pic.twitter.com/HoJK4L4qJZ
— Indianapolis Colts (@Colts) September 11, 2024
Indianapolis vs. Green Bay Prop Picks (AI)
Indianapolis vs. Green Bay Prediction (AI)
Remi, our AI sports genius, has been pouring over mountains of data from every facet between the Colts and Packers and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
Remi has been most keyed in on the linear correlation of factor knucklehead sportsbettors often put on player performance factors between a Colts team going up against a possibly unhealthy Packers team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Indianapolis vs Green Bay picks, computer picks Colts vs Packers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 6 |
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 4 |
EXECUTIVE
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 4 |
EXECUTIVE
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| NFL | 11/10 | PHI@GB | UNLOCK THIS PICK | 1 |
INTEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Colts Betting Trends
The Indianapolis Colts have performed well against the spread (ATS) recently, especially against NFC North opponents, with an 8-0 ATS record in their last eight matchups. However, they are 1-6 ATS in the third quarter of their last seven road games, indicating potential mid-game struggles.
Packers Betting Trends
The Green Bay Packers have a solid ATS record in the third quarter, going 13-6 in their last 19 games. However, they have struggled overall, particularly with injuries impacting their lineup. The Packers are 9-2 to the over with their team total in their last 11 games, showing a trend toward high-scoring games.
Colts vs. Packers Matchup Trends
The total points line is set at a relatively low 40.5, with a 55% chance of going over. Both teams have shown tendencies to cover the spread, but with Green Bay’s injuries, especially the absence of quarterback Jordan Love, the Colts have a 59% win probability according to simulations.
Indianapolis vs. Green Bay Game Info
What time does Indianapolis vs Green Bay start on September 15, 2024?
Indianapolis vs Green Bay starts on September 15, 2024 at 1:00 PM EST.
Where is Indianapolis vs Green Bay being played?
Venue: Lambeau Field.
What are the opening odds for Indianapolis vs Green Bay?
Spread: Green Bay +3.0
Moneyline: Indianapolis -175, Green Bay +145
Over/Under: 41
What are the records for Indianapolis vs Green Bay?
Indianapolis: (0-1) | Green Bay: (0-1)
What is the AI best bet for Indianapolis vs Green Bay?
Remi searched hard and crunched the numbers and found a prop bet for the Indianapolis Colts vs Green Bay Packers matchup: Anthony Richardson Anytime Touchdown Scorer . Prices move—always shop for the best number.
What are Indianapolis vs Green Bay trending bets?
The total points line is set at a relatively low 40.5, with a 55% chance of going over. Both teams have shown tendencies to cover the spread, but with Green Bay’s injuries, especially the absence of quarterback Jordan Love, the Colts have a 59% win probability according to simulations.
What are Indianapolis trending bets?
IND trend: The Indianapolis Colts have performed well against the spread (ATS) recently, especially against NFC North opponents, with an 8-0 ATS record in their last eight matchups. However, they are 1-6 ATS in the third quarter of their last seven road games, indicating potential mid-game struggles.
What are Green Bay trending bets?
GB trend: The Green Bay Packers have a solid ATS record in the third quarter, going 13-6 in their last 19 games. However, they have struggled overall, particularly with injuries impacting their lineup. The Packers are 9-2 to the over with their team total in their last 11 games, showing a trend toward high-scoring games.
Where can I find AI Picks for Indianapolis vs Green Bay?
See our latest NFL picks and odds pages for 2024 to compare prices before you bet.
Indianapolis vs. Green Bay Odds
AI algorithm Remi is pouring through mountains of data points on each line. In fact, anytime the Indianapolis vs Green Bay trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.
Indianapolis vs Green Bay Opening Odds
IND Moneyline:
-175 GB Moneyline: +145
IND Spread: -3
GB Spread: +3.0
Over/Under: 41
Indianapolis vs Green Bay Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
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Nov 13, 2025 8:15PM EST
New York Jets
New England Patriots
11/13/25 8:15PM
Jets
Patriots
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–
–
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+500
-835
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+12 (-114)
-12 (-112)
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O 43 (-110)
U 43 (-115)
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Nov 16, 2025 9:30AM EST
Washington Commanders
Miami Dolphins
11/16/25 9:30AM
Commanders
Dolphins
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–
–
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+132
-167
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+3 (-115)
-3 (-110)
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O 47 (-117)
U 47 (-109)
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Nov 16, 2025 1:00PM EST
Carolina Panthers
Atlanta Falcons
11/16/25 1PM
Panthers
Falcons
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–
–
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+163
-210
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+3.5 (-110)
-3.5 (-115)
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O 42.5 (-114)
U 42.5 (-112)
|
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Nov 16, 2025 1:00PM EST
Chicago Bears
Minnesota Vikings
11/16/25 1PM
Bears
Vikings
|
–
–
|
+128
-165
|
+3 (-112)
-3 (-113)
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O 48 (-113)
U 48 (-113)
|
|
|
Nov 16, 2025 1:00PM EST
Los Angeles Chargers
Jacksonville Jaguars
11/16/25 1PM
Chargers
Jaguars
|
–
–
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-157
+123
|
-2.5 (-120)
+2.5 (-107)
|
O 44 (-112)
U 44 (-114)
|
|
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Nov 16, 2025 1:00PM EST
Green Bay Packers
New York Giants
11/16/25 1PM
Packers
Giants
|
–
–
|
-435
+310
|
-8 (-112)
+8 (-114)
|
O 44 (-114)
U 44 (-112)
|
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Nov 16, 2025 1:00PM EST
Cincinnati Bengals
Pittsburgh Steelers
11/16/25 1PM
Bengals
Steelers
|
–
–
|
+205
-275
|
+5.5 (-114)
-5.5 (-112)
|
O 49 (-112)
U 49 (-114)
|
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|
Nov 16, 2025 1:00PM EST
Tampa Bay Buccaneers
Buffalo Bills
11/16/25 1PM
Buccaneers
Bills
|
–
–
|
+215
-286
|
+5.5 (-112)
-5.5 (-113)
|
O 48 (-113)
U 48 (-113)
|
|
|
Nov 16, 2025 1:00PM EST
Houston Texans
Tennessee Titans
11/16/25 1PM
Texans
Titans
|
–
–
|
-400
+285
|
-7 (-117)
+7 (-109)
|
O 39.5 (-109)
U 39.5 (-115)
|
|
|
Nov 16, 2025 4:05PM EST
San Francisco 49ers
Arizona Cardinals
11/16/25 4:05PM
49ers
Cardinals
|
–
–
|
-150
+112
|
-2.5 (-117)
+2.5 (-109)
|
O 48.5 (-112)
U 48.5 (-113)
|
|
|
Nov 16, 2025 4:05PM EST
Seattle Seahawks
Los Angeles Rams
11/16/25 4:05PM
Seahawks
Rams
|
–
–
|
+123
-155
|
+3 (-120)
-3 (-106)
|
O 48 (-112)
U 48 (-113)
|
|
|
Nov 16, 2025 4:25PM EST
Kansas City Chiefs
Denver Broncos
11/16/25 4:25PM
Chiefs
Broncos
|
–
–
|
-210
+160
|
-4 (-113)
+4 (-113)
|
O 44 (-115)
U 44 (-110)
|
|
|
Nov 16, 2025 4:25PM EST
Baltimore Ravens
Cleveland Browns
11/16/25 4:25PM
Ravens
Browns
|
–
–
|
-500
+350
|
-8.5 (-112)
+8.5 (-114)
|
O 41 (-113)
U 41 (-113)
|
|
|
Nov 16, 2025 8:20PM EST
Detroit Lions
Philadelphia Eagles
11/16/25 8:20PM
Lions
Eagles
|
–
–
|
+105
-134
|
+2 (-112)
-2 (-114)
|
O 47.5 (-110)
U 47.5 (-115)
|
|
|
Nov 17, 2025 8:15PM EST
Dallas Cowboys
Las Vegas Raiders
11/17/25 8:15PM
Cowboys
Raiders
|
–
–
|
-186
+145
|
-3.5 (-107)
+3.5 (-120)
|
O 50.5 (-112)
U 50.5 (-114)
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NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indianapolis Colts vs. Green Bay Packers on September 15, 2024 at Lambeau Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| LV@DEN | RILEY MOSS OVER 4.5 TACKLE + ASST | 54.8% | 4 | WIN |
| LV@DEN | UNDER 43 | 53.4% | 2 | WIN |
| ARI@DAL | BUDDA BAKER OVER 7.5 TACKLES + ASSTS | 54.4% | 4 | WIN |
| ARI@DAL | GEORGE PICKENS OVER 4.5 RECEPTIONS | 56.6% | 6 | WIN |
| DEN@HOU | WIL LUTZ OVER 1.5 MADE FIELD GOALS | 54.2% | 3 | LOSS |
| SEA@WAS | SEA -3 | 56.7% | 6 | WIN |
| IND@PIT | IND -3 | 56.8% | 6 | LOSS |
| LAC@TEN | LAC -9.5 | 56.2% | 6 | LOSS |
| CHI@CIN | CHI -2.5 | 52.6% | 2 | WIN |
| SEA@WAS | OVER 48 | 52.9% | 2 | WIN |
| SEA@WAS | JAYDEN DANIELS OVER 20.5 PASS COMP | 56.7% | 6 | LOSS |
| JAC@LV | JAC -140 | 64.2% | 7 | WIN |
| NO@LAR | LAR -14 | 55.0% | 4 | WIN |
| DEN@HOU | HOU -1.5 | 54.2% | 3 | LOSS |
| CAR@GB | GB -12.5 | 55.4% | 5 | LOSS |
| SF@NYG | NYG +2.5 | 56.1% | 5 | LOSS |
| BAL@MIA | TUA TAGOVAILOA UNDER 0.5 INT | 55.3% | 5 | LOSS |
| TB@NO | TB -3.5 | 52.3% | 1 | WIN |
| GB@PIT | GB -2.5 | 52.3% | 1 | WIN |
| SF@HOU | SF +2.5 | 56.0% | 6 | LOSS |
| NYG@PHI | NYG +7.5 | 53.9% | 3 | LOSS |
| BUF@CAR | CAR +7.5 | 54.2% | 3 | LOSS |
| DAL@DEN | DAL +3.5 | 55.0% | 4 | LOSS |
| MIA@ATL | MIA +7 | 54.3% | 4 | WIN |
| CLE@NE | CLE +7 | 56.8% | 6 | LOSS |
| TB@NO | BAKER MAYFIELD OVER 15.5 RUSH YDS | 56.6% | 6 | LOSS |
| MIN@LAC | JUSTIN HERBERT PASS ATT UNDER 35.5 | 55.5% | 5 | WIN |
| TB@DET | TB +6.5 | 54.4% | 4 | LOSS |
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |