AI NFL Picks — Week 8 (2025)

Updated: 2025-09-13T08:00:00-06:00

Our Week 8 NFL computer picks combine play-by-play data, simulations, and market moves to surface ATS, moneyline, over/under, and player prop edges. Below you’ll find AI predictions with confidence ratings, plus best bets and buy-to numbers.

Pro tip: prices move. Refresh before kickoff to catch new edges and verify current odds.

AI Sports Betting Algorithm Remi

Best Week 8
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WEEK 8 NFL Computer Picks (ATS, ML, O/U)

WEEK 8 NFL Odds

WEEK 8 NFL ODDS COMPARISON

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Live AI NFL Picks — Week 8

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number.

Below is our current AI NFL picks Week 8, NFL computer picks Week 8, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 9/15 TB@HOU UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 9/15 LAC@LV UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 9/15 TB@HOU UNLOCK THIS PICK 2 INTEL Locked INTEL
NFL 9/15 LAC@LV UNLOCK THIS PICK 1 INTEL Locked INTEL
NFL 9/15 LAC@LV UNLOCK THIS PICK 1 INTEL Locked INTEL

Week 8 Storylines & Angles

Offense vs. Defense Mismatches

Quarterback & Scheme Trends

Travel, Rest & Situational Spots

Weather & Late-Breaking Injuries

AI NFL Picks — Week 8 (2025). Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

NFL Week 8 Best Bets & Model Edges

  • Price sensitivity: we bet prices, not teams. If the market moves beyond our “buy-to” number, expected value drops.

  • Unit Plays (1–10): reflect signal quality, injury/variance risk, and line availability.

  • Staking: default stake scales with edge and volatility; avoid over-exposure to correlated outcomes.

  • Closing-Line Value (CLV): consistently beating the close is a strong quality signal—even over small samples.

Line Movement Tracker — Week 8

Remi is pouring through tons of data on each player. In fact, anytime the NFL week 8 trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps almost always follow normal, predictable betting trends.

Games PTS ML SPR O/U
Sep 18, 2025 8:15PM EDT
Miami Dolphins
Buffalo Bills
9/18/25 8:15PM
Dolphins
Bills
+540
-910
+12.5 (-110)
-12.5 (-115)
O 49.5 (-112)
U 49.5 (-114)
Sep 21, 2025 1:00PM EDT
New York Jets
Tampa Bay Buccaneers
9/21/25 1PM
Jets
Buccaneers
+275
-345
+7 (+100)
-7 (-120)
O 45.5 (-110)
U 45.5 (-110)
Sep 21, 2025 1:00PM EDT
Las Vegas Raiders
Washington Commanders
9/21/25 1PM
Raiders
Commanders
+154
-185
+3.5 (-110)
-3.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Sep 21, 2025 1:00PM EDT
Atlanta Falcons
Carolina Panthers
9/21/25 1PM
Falcons
Panthers
-220
+160
-4.5 (-113)
+4.5 (-112)
O 43.5 (-114)
U 43.5 (-112)
Sep 21, 2025 1:00PM EDT
Green Bay Packers
Cleveland Browns
9/21/25 1PM
Packers
Browns
-480
+340
-8 (-110)
+8 (-115)
O 42.5 (-113)
U 42.5 (-113)
Sep 21, 2025 1:00PM EDT
Houston Texans
Jacksonville Jaguars
9/21/25 1PM
Texans
Jaguars
-105
-115
+1.5 (-118)
-1.5 (-102)
O 43.5 (-110)
U 43.5 (-110)
Sep 21, 2025 1:00PM EDT
Pittsburgh Steelers
New England Patriots
9/21/25 1PM
Steelers
Patriots
-120
-107
-1 (-112)
+1 (-114)
O 44.5 (-112)
U 44.5 (-114)
Sep 21, 2025 1:00PM EDT
Cincinnati Bengals
Minnesota Vikings
9/21/25 1PM
Bengals
Vikings
+125
-167
+3 (-110)
-3 (-114)
O 41.5 (-114)
U 41.5 (-110)
Sep 21, 2025 1:01PM EDT
Los Angeles Rams
Philadelphia Eagles
9/21/25 1:01PM
Rams
Eagles
+155
-195
+3.5 (-114)
-3.5 (-112)
O 44.5 (-115)
U 44.5 (-110)
Sep 21, 2025 1:01PM EDT
Indianapolis Colts
Tennessee Titans
9/21/25 1:01PM
Colts
Titans
-186
+145
-3.5 (-108)
+3.5 (-118)
O 43.5 (-112)
U 43.5 (-114)
Sep 21, 2025 4:05PM EDT
Denver Broncos
Los Angeles Chargers
9/21/25 4:05PM
Broncos
Chargers
+120
-142
+2.5 (-110)
-2.5 (-110)
O 44.5 (-115)
U 44.5 (-105)
Sep 21, 2025 4:05PM EDT
New Orleans Saints
Seattle Seahawks
9/21/25 4:05PM
Saints
Seahawks
+260
-360
+7.5 (-118)
-7.5 (-108)
O 41.5 (-113)
U 41.5 (-113)
Sep 21, 2025 4:25PM EDT
Dallas Cowboys
Chicago Bears
9/21/25 4:25PM
Cowboys
Bears
-103
-125
+1.5 (-113)
-1.5 (-112)
O 50 (-110)
U 50 (-115)
Sep 21, 2025 4:26PM EDT
Arizona Cardinals
San Francisco 49ers
9/21/25 4:26PM
Cardinals
49ers
+100
-127
+1.5 (-113)
-1.5 (-113)
O 43.5 (-113)
U 43.5 (-113)
Sep 21, 2025 8:21PM EDT
Kansas City Chiefs
New York Giants
9/21/25 8:21PM
Chiefs
Giants
-286
+215
-6 (-112)
+6 (-113)
O 44.5 (-109)
U 44.5 (-117)
Sep 22, 2025 8:15PM EDT
Detroit Lions
Baltimore Ravens
9/22/25 8:15PM
Lions
Ravens
+205
-265
+6 (-115)
-6 (-109)
O 51.5 (-109)
U 51.5 (-117)

How Our AI Picks Work

Our NFL model blends play-by-play efficiency, drive-level simulations, and market-aware priors. We incorporate injury reports, rest/travel effects, and weather to adjust team strength and total expectations. Each game is simulated thousands of times to produce fair prices; the displayed Model Edge % is the gap between our fair price and the current market.

  • Market-aware: incorporates liquidity windows and closing-line efficiency.

  • Context-adjusted: rest days, travel, altitude, tempo, and scheme tendencies.

  • Transparency: we show confidence, edges, and track CLV and ROI.

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Remi, our AI sports algorithm, has been pouring over mountains of data from every angle across NFL week 8 using recursive machine learning to cutting-edge AI to examine the data to a single cover probability.

Remi has been most fixated on the linear correlation of weight human bettors tend to put on week 8’s strengths factors between a visitors team going up against a possibly tired home teams. It appears the true game analytics might reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

FAQ — Week 8 NFL AI Picks

Right on this page. We publish Week 8 NFL computer picks organized by Against the Spread (ATS), Moneyline, Totals (Over/Under), and Player Props so you can jump straight to the markets you bet most.

“Best bets” are our highest-confidence Week 8 NFL AI picks based on fair price vs. current odds. Look for larger Model Edge % and higher confidence stars; those signal stronger value at widely available prices.

We combine play-by-play data, drive-level simulations, and market-aware priors. The model produces a fair price for each side/total/prop, then compares it to live odds to surface Week 8 edges worth betting.

Throughout the week and up to kickoff. As injuries, weather, and prices move, our projections refresh—so check back closer to game time for the most accurate read on Week 8 value.

Yes. Our Week 8 NFL AI picks include props such as anytime touchdown, rushing/receiving yards, passing yards, attempts, and more when markets are liquid and pricing shows an edge.

When correlations and prices justify it, we highlight SGP concepts tied to our Week 8 AI edges—think side/total anchored to complementary player props. We only list combos when expected value remains positive.

Model Edge % is the gap between our fair price and the current line/price. Units (1–10) summarize signal quality, volatility, and line availability for Week 8 NFL AI picks.

“Buy-to” is the furthest playable number before expected value disappears. If the market pushes past that level, the Week 8 pick may no longer qualify—wait for a better price or skip the bet.

Yes. We grade results against widely available prices at publish time and monitor CLV to gauge process quality. You’ll also find recent record and ROI to keep Week 8 performance transparent.

Scale stake size with edge and volatility. Larger Model Edge % and higher confidence typically merit slightly larger positions, but avoid over-exposure to correlated outcomes within the same game.

Sometimes. Teasers can make sense around key numbers when totals and pricing conditions are favorable. If our Week 8 read flags teaser value, we’ll note the recommended legs and limits.

Materially. The model adjusts team strength, pace, and totals for late scratches, snap-count news, wind/rain/cold thresholds, altitude, rest, and travel. Those inputs can change edges close to kickoff.

Use your preferred odds screen or our odds links from this page. Shopping lines is essential—Model Edge % is calculated against available prices, and the best number often determines long-term ROI.

Yes. Enable notifications or subscribe for alerts so you catch new Week 8 AI picks, notable line moves, and updates to buy-to ranges before the market fully adjusts.

Past Weekly NFL AI Picks

    LEAN     %WIN     UNITS RESULT
PHI@KC PHI -115 56.7% 6 WIN
SF@NO SF -3 58.8% 8 WIN
SEA@PIT OVER 40 54.9% 4 WIN
CAR@ARI BRYCE YOUNG INTERCEPTIONS UNDER 0.5 56.4% 6 LOSS
DEN@IND JOSH DOWNS RECEPTIONS OVER 3.5 54.7% 4 WIN
ATL@MIN BIJAN ROBINSON RUSH + REC YDS OVER 94.5 53.4% 3 WIN
WAS@GB WAS +3.5 56.5% 6 LOSS
WAS@GB JORDAN LOVE OVER 5.5 RUSH YDS 54.7% 4 WIN
MIN@CHI CALEB WILLIAMS OVER 219.5 PASS YDS 53.4% 3 LOSS
TEN@DEN DEN -8.5 55.3% 5 LOSS
SF@SEA SF -115 54.6% 4 WIN
SF@SEA KENNETH WALKER III UNDER 79.5 RUSH+REC YDS 54.6% 4 WIN
CAR@JAC TANK BIGSBY OVER 10.5 RUSH ATT 56.1% 6 LOSS
KC@LAC JUSTIN HERBERT UNDER 0.5 INT 54.1% 3 WIN
DAL@PHI GEORGE PICKENS LONGEST RECEPTION OVER 22.5 YDS 54.1% 4 LOSS
KC@PHI JUJU SMITH-SCHUSTER UNDER 16.5 RECV YDS 53.90% 5 WIN
KC@PHI DEVONTA SMITH LONGEST RECEPTION OVER 20.5 YDS 54.40% 6 WIN
KC@PHI PATRICK MAHOMES UNDER 68.3% PASS COMP 55.00% 8 WIN
KC@PHI JALEN HURTS LONGEST RUSH OVER 12.5 YDS 55.60% 8 WIN
BUF@KC DALTON KINCAID OVER 29.5 RECV YDS 55.10% 8 LOSS
WAS@PHI DEVONTA SMITH OVER 3.5 RECEPTIONS 55.80% 8 WIN
BUF@KC JAMES COOK ANYTIME TD 53.00% 5 WIN
LAR@PHI SAQUON BARKLEY UNDER 128 RUSH + REC YDS 53.20% 5 LOSS
BAL@BUF LAMAR JACKSON OVER 54.5 RUSH YDS 54.50% 6 LOSS
HOU@KC C.J. STROUD RUSH YDS UNDER 14.5 53.10% 5 LOSS
WAS@DET JAMESON WILLIAMS RUSH YDS OVER 1.5 53.30% 5 WIN
WAS@DET JARED GOFF PASS COMP % UNDER 72.3 54.30% 6 WIN
MIN@LAR COOPER KUPP ANYTIME TOUCHDOWN 52.60% 3 LOSS
MIN@LAR MATTHEW STAFFORD OVER 21.5 PASS COMP 54.10% 6 LOSS
WAS@TB BRIAN ROBINSON JR OVER 1.5 REC TARGETS 53.50% 5 WIN
WAS@TB BAKER MAYFIELD UNDER 33.5 PASS ATT 54.90% 6 WIN
GB@PHI JALEN HURTS OVER 67.1 PASS COMP PERCENTAGE 54.60% 6 LOSS
LAC@HOU J.K. DOBBINS ANYTIME TD 52.80% 3 LOSS
LAC@HOU LAC -2.5 53.40% 3 LOSS
LAC@HOU JUSTIN HERBERT OVER 19.5 RUSH YDS 53.40% 5 LOSS
PIT@BAL JUSTICE HILL OVER 2.5 RECEPTIONS 55.30% 8 WIN
MIN@DET DET -3 53.90% 3 WIN
KC@DEN DEN -11.5 53.80% 3 WIN
MIN@DET T.J. HOCKENSON RECV YDS OVER 46.5 55.00% 6 LOSS
SEA@LAR ZACH CHARBONNET RECV YDS OVER 18.5 53.90% 8 WIN
TB@NO BAKER MAYFIELD PASS ATT OVER 31.5 53.80% 8 WIN
CIN@PIT CIN -130 56.20% 3 WIN
CIN@PIT RUSSELL WILSON PASS ATT OVER 31.5 54.60% 6 LOSS
CLE@BAL ELIJAH MOORE RECV TARGETS OVER 5.5 54.30% 6 LOSS
CIN@PIT PAT FREIERMUTH ANYTIME TD (UNITS ADJ FOR +400 ODDS) 52.50% 9 WIN
DET@SF DET -3.5 54.10% 4 WIN
DET@SF JAHMYR GIBBS LONGEST RUSH OVER 16.5 YDS 53.60% 5 WIN
DET@SF BROCK PURDY UNDER 4.5 RUSH ATT 53.80% 5 WIN
DET@SF ISAAC GUERENDO UNDER 15.5 RUSH ATT 55.30% 8 WIN
DAL@PHI OVER 37.5 53.40% 3 WIN
LV@NO LV -125 57.20% 4 WIN