Must Bet NFL Week 7 AI Picks, Predictions & Hidden Market Mistakes
Updated: 2025-10-12T08:00:00-06:00By Remi at Leans.AI — AI picks for ATS, ML, OU & props
Our Week 7 NFL computer picks combine play-by-play data, simulations, and market moves to surface ATS, moneyline, over/under, and player prop edges. Below you’ll find AI predictions with confidence ratings, plus best bets and buy-to numbers.
Pro tip: prices move. Refresh before kickoff to catch new edges and verify current odds.
Best Week 7
NFL AI Player Prop
- Remi's searched hard and found the best prop for this matchup: J. Daniels over 217.5 Passing Yards.
WEEK 7 NFL Computer Picks (ATS, ML, O/U)
WEEK 7 NFL Odds
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Week 7 of the 2025 NFL season brings storylines that could shape playoff trajectories and MVP races alike, as several divisional clashes and primetime showdowns highlight a schedule packed with intrigue. The headliner comes from the NFC, where the San Francisco 49ers travel to Philadelphia for a rematch of last year’s playoff thriller — Brock Purdy and Jalen Hurts once again leading two powerhouse offenses that mirror each other in physicality and precision. In the AFC, the Baltimore Ravens and Kansas City Chiefs square off in a potential conference title preview, pitting Lamar Jackson’s dynamic rushing attack against Patrick Mahomes’ surgical passing game. Both quarterbacks enter in elite form, and their matchup could redefine the race for the league’s top seed. Meanwhile, teams like the Detroit Lions and Houston Texans continue to demand national attention, with Jared Goff and C.J. Stroud leading offenses that have proven they belong among the NFL’s elite.
Beyond the marquee names, Week 7 is full of trap games and statement opportunities. The Miami Dolphins face a sneaky test against the New York Jets’ ferocious pass rush, while the Dallas Cowboys head to Washington in a divisional game that often defies logic and trends. Injuries and midseason fatigue are beginning to influence rotations — meaning coaching adjustments, tempo control, and situational awareness will separate contenders from pretenders. For bettors and analysts alike, “Week 7 NFL AI Picks” offers an opportunity to cut through the noise, blending advanced metrics like EPA per play, success rate, and third-down efficiency with the unpredictable human element that defines October football. As the weather cools and the intensity rises, Week 7 stands as a turning point for teams trying to prove whether their early-season success is sustainable — or simply smoke and mirrors.
Week 7 of the 2025 NFL season arrives at the perfect midpoint — where contenders begin separating from the pack and desperate teams start treating every game like a playoff elimination. The spotlight shines brightest on the AFC this week, with the Buffalo Bills facing the Cincinnati Bengals in a rematch that promises fireworks. Josh Allen and Joe Burrow headline two of the league’s most efficient offenses, both top-five in explosive plays and red-zone touchdown rate entering the week. Meanwhile, the Cleveland Browns’ ferocious defense, led by Myles Garrett, faces off against C.J. Stroud and the Texans in a matchup that tests how well Houston’s young offensive line can withstand elite pass-rush pressure. Over in the NFC, all eyes are on the Green Bay Packers as Jordan Love looks to outduel Jared Goff and the surging Detroit Lions in a game that could have early playoff seeding implications.
But the undercard battles might be just as compelling. The New York Giants and New Orleans Saints meet in a cross-conference matchup where Daniel Jones and Derek Carr both need strong outings to silence critics, while in Los Angeles, Justin Herbert and the Chargers host the surging Chicago Bears in a primetime clash of two ascending young quarterbacks. Travel fatigue, short rest, and shifting weather patterns will all play subtle but significant roles as analytics meet adversity. “Week 7 NFL AI Picks” dives deep into these pivotal matchups, identifying where efficiency metrics, pace of play, and situational trends intersect with real-world football dynamics. As the season grinds forward, Week 7 isn’t just another checkpoint — it’s where data and determination start to decide who’s for real and who’s fading fast.
Jacob Rufino of Elgin & Devin Krueger of Larkin were selected players of the game for boys varsity. #ThisisHSFootball pic.twitter.com/sjXGYtu1rp
— Chicago Bears (@BearsOutreach) October 7, 2025
Live AI NFL Picks — Week 7
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL schedule.
Below is our current AI NFL picks Week 7, NFL computer picks Week 7, best bets, model edges, confidence ratings.
 |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
Week 7 Storylines & Angles
Offense vs. Defense Mismatches
Week 7 of the 2025 NFL season delivers a fascinating slate of offensive-versus-defensive chess matches, where advanced metrics like EPA/play, success rate, and red-zone touchdown efficiency will likely dictate outcomes more than ever. The Miami Dolphins still sit atop the league in offensive EPA/play thanks to Tua Tagovailoa’s quick-trigger accuracy and Mike McDaniel’s motion-heavy scheme that keeps defenses off balance, but this week’s clash with the New York Jets’ relentless front seven could disrupt that rhythm. Quinnen Williams and Jermaine Johnson have anchored a pass rush that ranks top-three in pressure rate, and Miami’s ability to hold up in protection — particularly against simulated pressures — will determine whether they maintain their trademark explosiveness. In the NFC, the Detroit Lions continue to thrive on efficiency rather than flash, ranking among the top five in success rate and red-zone touchdown conversion behind Jared Goff’s pinpoint passing and Ben Johnson’s precision play-calling. However, they’ll be tested by a Green Bay defense that’s excelled in limiting big plays and forcing third-and-longs through disguised coverage rotations.
Explosive play creation and pass-rush pressure will define the week’s biggest games, especially in matchups like Kansas City versus Baltimore, where both Patrick Mahomes and Lamar Jackson rank inside the top ten in total EPA but generate offense in radically different ways. The Chiefs’ methodical pace and league-best red-zone scoring percentage contrast sharply with Baltimore’s quick-strike capabilities and heavy reliance on scramble efficiency. Defensively, the 49ers and Browns continue to set the bar — San Francisco’s defense leads the league in opponent success rate, while Cleveland’s front, led by Myles Garrett, has terrorized quarterbacks with a pressure rate over 40%. That presents intriguing betting edges for teams that thrive on pace and precision, as slower-tempo, ball-control offenses like Dallas or Tennessee could find themselves suffocated if they fail to stay ahead of schedule. “Week 7 NFL AI Picks” digs deep into those contrasts, identifying where elite protection meets elite pass rush and where red-zone mastery might be the deciding edge in a league increasingly driven by situational execution and explosive efficiency.
Quarterback & Scheme Trends
Quarterback play in Week 7 of the 2025 NFL season is all about adaptation — how signal-callers handle pressure, exploit motion, and thrive in situational play-calling as defenses evolve midseason. Patrick Mahomes continues to redefine efficiency against the blitz, completing over 72% of his throws and posting a top-five EPA/play when defenses bring extra rushers. His pre-snap mastery and the Chiefs’ increased use of motion — now on over 60% of offensive snaps — make it nearly impossible for defenses to disguise coverage. Meanwhile, Lamar Jackson remains a blueprint for dual-threat unpredictability, thriving under new coordinator Todd Monken’s balanced play-calling that blends designed runs with rhythm throws off play-action. Jackson’s efficiency under pressure is peaking, as his quick processing and off-script mobility have turned broken plays into explosive gains. In contrast, quarterbacks like Tua Tagovailoa and Brock Purdy face tougher adjustments this week, with both set to encounter defenses ranked in the top five in pressure rate. For Tagovailoa, motion and tempo will be crucial to offset the Jets’ disguised blitzes, while Purdy must rely on Kyle Shanahan’s heavy under-center usage to keep linebackers honest against play-action.
Scheme variation and situational play-calling continue to define the league’s sharpest offenses heading into Week 7. Jared Goff and the Detroit Lions are a model of pre-snap discipline and controlled aggression, thriving with one of the highest success rates from under center thanks to perfectly timed play-action concepts that set up deep shots. Josh Allen, on the other hand, has excelled in late-down improvisation but still faces volatility — his pressure versus blitz splits show that while he’s dangerous against man pressure, simulated zone looks can bait him into risky throws. Teams like the 49ers and Cowboys continue to emphasize motion-heavy misdirection to open windows for their quarterbacks, while coordinators such as Kellen Moore in Los Angeles are dialing up more condensed formations to protect young passers like Justin Herbert. Across the league, Week 7’s theme is control versus chaos — which quarterbacks can maintain rhythm when the pocket collapses, and which coordinators can scheme motion, pace, and balance to keep defenses guessing. The “Week 7 NFL AI Picks” break down these trends, highlighting where elite preparation and adaptable play design give quarterbacks the upper hand in games where timing and poise mean everything.
Travel, Rest & Situational Spots
Week 7 of the 2025 NFL season presents a gauntlet of tricky travel, rest, and situational dynamics that could quietly shape outcomes as much as talent itself. The New York Giants face one of the toughest scheduling spots of the week, heading to Denver for a high-altitude matchup against the Broncos on a short turnaround after a physical divisional game. Historically, teams traveling from the East Coast to Mile High with less than seven days’ rest have underperformed both straight up and against the spread due to fatigue and body-clock disruption. Meanwhile, the Los Angeles Chargers return home after two consecutive road games, a potential “let-down” spot even against a beatable opponent. Conversely, the Dallas Cowboys enjoy one of the more favorable rest setups, coming off an extended week after a Thursday night appearance to host a Washington team that’s been battling injuries and travel fatigue from back-to-back road contests. These subtle factors — the kind that analytics often struggle to quantify — frequently create value edges when blended with matchup metrics like EPA and success rate.
Cross-country travel and rivalry dynamics add another layer of volatility to Week 7’s slate. The Miami Dolphins, who have looked nearly unstoppable at home, face a body-clock disadvantage in an early kickoff at Seattle, where noise, travel distance, and time-zone fatigue have historically hampered high-tempo offenses. The same can be said for the 49ers, who could be caught in a “look-ahead” situation if they peek toward their upcoming divisional showdown instead of focusing on an inferior opponent this week. Divisional rematches like Eagles–Giants and Chiefs–Raiders bring emotional spikes and schematic familiarity, often neutralizing talent disparities and tightening betting lines. Coaches like Andy Reid and Sean McVay tend to excel in these situational spots, leveraging extra rest and travel planning to offset physical disadvantages. As “Week 7 NFL AI Picks” highlights, these travel and scheduling nuances — from altitude effects to emotional fatigue — are the hidden variables that often swing outcomes when pure analytics can’t explain why a superior team suddenly stumbles.
Weather & Late-Breaking Injuries
Weather could quietly become one of the biggest storylines in Week 7 of the 2025 NFL season, with several outdoor matchups potentially facing wind and rain that could swing totals and offensive efficiency. Forecasts currently point to gusty conditions in Chicago and Cleveland, two cities already known for low-scoring, physical games when wind speeds exceed 15–20 mph — a threshold that historically reduces deep-passing accuracy and overall yards per attempt by more than 10%. Teams like the Browns, who thrive on a ground-and-pound approach behind Nick Chubb and Jerome Ford, could benefit from adverse conditions against a more pass-reliant opponent like Miami. Similarly, potential rain in the Northeast could impact aerial attacks for the Jets and Patriots, where both offenses already rank in the bottom third in explosive pass rate. Snow isn’t expected this early in the year, but cold, wet fields could influence kicking accuracy and red-zone decision-making, especially for coaches who lean heavily on analytics-based fourth-down aggression. Bettors eyeing totals or prop markets should monitor weather closely, as even moderate wind can flip a projected shootout into a trench battle that favors unders and power-run offenses.
On the personnel side, Week 7 features several key injury situations that could reshape offensive dynamics and snap distributions. The 49ers continue to monitor Christian McCaffrey’s workload, as calf tightness has limited his practice reps and could lead to more snaps for Elijah Mitchell and Jordan Mason. In Miami, Jaylen Waddle remains questionable with a lingering oblique issue, meaning Tua Tagovailoa may lean even more on Tyreek Hill and tight end Jonnu Smith in short-area concepts. The Chiefs expect Travis Kelce to play through an ankle tweak, though his red-zone usage might be reduced slightly to manage pain and workload. Defensively, the Ravens could get safety Kyle Hamilton back, which would significantly boost their coverage against explosive passing teams. On the flip side, the Cowboys are monitoring Micah Parsons’ knee after he left last week’s game briefly — any limitations there could drastically affect Dallas’s pass-rush effectiveness. As “Week 7 NFL AI Picks” notes, combining these injury updates with evolving weather forecasts creates a sharper analytical edge, especially for bettors looking to identify mispriced totals or player prop inefficiencies before kickoff.
Check up to the minute weather forecasts here.
Credit: USA TODAY/IMAGN
NFL Week 7 Best Bets & AI Prop Picks
Week 7 NFL Best Bet – Pro Tips
Note Price sensitivity: We crunch numbers, not teams. If the market moves beyond our
buy-to number, expected value decays and the edge can disappear. Respect the price.
Unit sizing (1–10): Our unit scale reflects model signal strength, injury/variance risk,
and current line availability. Higher units = stronger conviction, not permission to over-expose.
Staking & correlation: Default stake scales with edge and volatility. Avoid stacking too many
correlated outcomes (same game, same player ladder) unless you deliberately size down.
Closing-Line Value (CLV): Beating the close consistently is a quality signal—even across small samples.
Track your entry vs. close; it’s the most reliable feedback loop for long-term profitability.
Week 7 Line Movement
Every pick includes a playable to line or price (e.g., -2.5, Over 44.5, +115). If you can’t get that number or better, consider passing or reducing stake. Lines move—check back for live updates in our Live AI Picks stream and see quick notes in Odds & Line Movement.
Note – all of our data is for informational purposes only and not a recommendation as to whether or how to wager.
A movie 🎥 pic.twitter.com/F8vzBCN7X2
— Washington Commanders (@Commanders) October 8, 2025
Line Movement Tracker — Week 7
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Nov 20, 2025 8:15PM EST
Buffalo Bills
Houston Texans
11/20/25 8:15PM
Bills
Texans
|
–
–
|
-285
+234
|
-6 (-110)
+6 (-110)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
Seattle Seahawks
Tennessee Titans
11/23/25 1PM
Seahawks
Titans
|
–
–
|
-950
+637
|
-13.5 (-110)
+13.5 (-110)
|
O 40 (-110)
U 40 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
New England Patriots
Cincinnati Bengals
11/23/25 1PM
Patriots
Bengals
|
–
–
|
-380
+303
|
-7 (-110)
+7 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
New York Giants
Detroit Lions
11/23/25 1PM
Giants
Lions
|
–
–
|
+415
-550
|
+10.5 (-114)
-10.5 (-106)
|
O 50 (-110)
U 50 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
New York Jets
Baltimore Ravens
11/23/25 1PM
Jets
Ravens
|
–
–
|
+709
-1100
|
+13.5 (-113)
-13.5 (-107)
|
O 44 (-110)
U 44 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
Indianapolis Colts
Kansas City Chiefs
11/23/25 1PM
Colts
Chiefs
|
–
–
|
+152
-173
|
+3.5 (-125)
-3.5 (+105)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 23, 2025 1:00PM EST
Minnesota Vikings
Green Bay Packers
11/23/25 1PM
Vikings
Packers
|
–
–
|
+234
-285
|
+6.5 (-115)
-6.5 (-105)
|
O 40.5 (-115)
U 40.5 (-105)
|
|
|
Nov 23, 2025 1:00PM EST
Pittsburgh Steelers
Chicago Bears
11/23/25 1PM
Steelers
Bears
|
–
–
|
+120
-140
|
+2.5 (-110)
-2.5 (-110)
|
O 45 (-110)
U 45 (-110)
|
|
|
Nov 23, 2025 4:05PM EST
Cleveland Browns
Las Vegas Raiders
11/23/25 4:05PM
Browns
Raiders
|
–
–
|
+177
-205
|
+4 (-110)
-4 (-110)
|
O 36 (-105)
U 36 (-115)
|
|
|
Nov 23, 2025 4:05PM EST
Jacksonville Jaguars
Arizona Cardinals
11/23/25 4:05PM
Jaguars
Cardinals
|
–
–
|
-160
+140
|
-3 (-105)
+3 (-115)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
|
Nov 23, 2025 4:25PM EST
Philadelphia Eagles
Dallas Cowboys
11/23/25 4:25PM
Eagles
Cowboys
|
–
–
|
-170
+149
|
-3.5 (+104)
+3.5 (-124)
|
O 47.5 (-115)
U 47.5 (-105)
|
|
|
Nov 23, 2025 4:25PM EST
Atlanta Falcons
New Orleans Saints
11/23/25 4:25PM
Falcons
Saints
|
–
–
|
+110
-130
|
+2 (-110)
-2 (-110)
|
O 39.5 (-115)
U 39.5 (-105)
|
|
|
Nov 23, 2025 8:20PM EST
Tampa Bay Buccaneers
Los Angeles Rams
11/23/25 8:20PM
Buccaneers
Rams
|
–
–
|
+260
-320
|
+6.5 (-105)
-6.5 (-115)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 24, 2025 8:15PM EST
Carolina Panthers
San Francisco 49ers
11/24/25 8:15PM
Panthers
49ers
|
–
–
|
+274
-340
|
+7 (-115)
-7 (-105)
|
O 48.5 (-115)
U 48.5 (-105)
|
|
|
Nov 27, 2025 1:00PM EST
Green Bay Packers
Detroit Lions
11/27/25 1PM
Packers
Lions
|
–
–
|
+138
-164
|
+3 (-119)
-3 (-101)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 27, 2025 4:30PM EST
Kansas City Chiefs
Dallas Cowboys
11/27/25 4:30PM
Chiefs
Cowboys
|
–
–
|
-186
+156
|
-4.5 (-110)
+4.5 (-110)
|
O 51 (-110)
U 51 (-110)
|
|
|
Nov 27, 2025 8:20PM EST
Cincinnati Bengals
Baltimore Ravens
11/27/25 8:20PM
Bengals
Ravens
|
–
–
|
+350
-450
|
+7.5 (-115)
-7.5 (-105)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
|
Nov 28, 2025 3:00PM EST
Chicago Bears
Philadelphia Eagles
11/28/25 3PM
Bears
Eagles
|
–
–
|
+280
-350
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Nov 30, 2025 1:00PM EST
San Francisco 49ers
Cleveland Browns
11/30/25 1PM
49ers
Browns
|
–
–
|
-340
+275
|
-6.5 (-110)
+6.5 (-110)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
|
Nov 30, 2025 1:00PM EST
Jacksonville Jaguars
Tennessee Titans
11/30/25 1PM
Jaguars
Titans
|
–
–
|
-350
+280
|
-7 (-110)
+7 (-110)
|
O 42 (-110)
U 42 (-110)
|
How Our AI Picks Work
Our NFL model blends play-by-play efficiency, drive-level simulations, and market-aware priors. We incorporate injury reports, rest/travel effects, and weather to adjust team strength and total expectations. Each game is simulated thousands of times to produce fair prices; the displayed Model Edge % is the gap between our fair price and the current market.
Market-aware: incorporates liquidity windows and closing-line efficiency.
Context-adjusted: rest days, travel, altitude, tempo, and scheme tendencies.
Transparency: we show confidence, edges, and track CLV and ROI.
Remi, our AI sports wizard, has been pouring over millions of data from every past game across NFL week 7 using recursive machine learning to industry leading AI to boil down the data to a single cover probability.
Remi has been most focused on the unproportionally assigned factor human bettors tend to put on coaching factors between a visitors team going up against a possibly rested home teams. In reality, the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
FAQ — Week 7 NFL
Where can I see Week 7 NFL AI picks by bet type?
Right on this page. We publish Week 7 NFL computer picks organized by Against the Spread (ATS), Moneyline, Totals (Over/Under), and Player Props so you can jump straight to the markets you bet most.
What are the “best bets” for Week 7 according to the model?
“Best bets” are our highest-confidence Week 7 NFL AI picks based on fair price vs. current odds. Look for larger Model Edge % and higher confidence stars; those signal stronger value at widely available prices.
How are your Week 7 NFL computer picks generated?
We combine play-by-play data, drive-level simulations, and market-aware priors. The model produces a fair price for each side/total/prop, then compares it to live odds to surface Week 7 edges worth betting.
How often do you update Week 7 NFL AI picks?
Throughout the week and up to kickoff. As injuries, weather, and prices move, our projections refresh—so check back closer to game time for the most accurate read on Week 7 value.
Do your Week 7 picks include player props like anytime TD or yardage?
Yes. Our Week 7 NFL AI picks include props such as anytime touchdown, rushing/receiving yards, passing yards, attempts, and more when markets are liquid and pricing shows an edge.
Do you post same-game parlay (SGP) ideas for Week 7?
When correlations and prices justify it, we highlight SGP concepts tied to our Week 7 AI edges—think side/total anchored to complementary player props. We only list combos when expected value remains positive.
What do Model Edge % and units mean?
Model Edge % is the gap between our fair price and the current line/price. Units (1–10) summarize signal quality, volatility, and line availability for Week 7 NFL AI picks.
What are “buy-to” numbers, and what if the line moves?
“Buy-to” is the furthest playable number before expected value disappears. If the market pushes past that level, the Week 7 pick may no longer qualify—wait for a better price or skip the bet.
Do you track closing-line value (CLV) and ROI for Week 7?
Yes. We grade results against widely available prices at publish time and monitor CLV to gauge process quality. You’ll also find recent record and ROI to keep Week 7 performance transparent.
How should I size bets on Week 7 NFL AI picks?
Scale stake size with edge and volatility. Larger Model Edge % and higher confidence typically merit slightly larger positions, but avoid over-exposure to correlated outcomes within the same game.
Are teasers viable for Week 7?
Sometimes. Teasers can make sense around key numbers when totals and pricing conditions are favorable. If our Week 7 read flags teaser value, we’ll note the recommended legs and limits.
How do injuries, weather, and travel impact Week 7 NFL picks?
Materially. The model adjusts team strength, pace, and totals for late scratches, snap-count news, wind/rain/cold thresholds, altitude, rest, and travel. Those inputs can change edges close to kickoff.
Where can I compare Week 7 NFL odds to shop the best number?
Use your preferred odds screen or our odds links from this page. Shopping lines is essential—Model Edge % is calculated against available prices, and the best number often determines long-term ROI.
Can I get alerts when new Week 7 NFL AI picks post or when lines move to buy-to?
Yes. Enable notifications or subscribe for alerts so you catch new Week 7 AI picks, notable line moves, and updates to buy-to ranges before the market fully adjusts.
Past NFL AI Picks
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| DAL@LV | UNDER 49.5 | 54.3% | 3 | WIN |
| DAL@LV | BROCK BOWERS OVER 6.5 RECEPTIONS | 57.6% | 7 | WIN |
| CAR@ATL | BRYCE YOUNG UNDER 0.5 INT | 56.1% | 6 | WIN |
| KC@DEN | PATRICK MAHOMES UNDER 266.5 PASS YDS | 55.3% | 5 | LOSS |
| SF@ARI | SF -3 | 56.4% | 6 | WIN |
| GB@NYG | GB -7 | 54.3% | 4 | PUSH |
| LAC@JAC | LAC -3 | 53.2% | 3 | LOSS |
| SEA@LAR | SEA +3.5 | 57.2% | 7 | WIN |
| CHI@MIN | MIN -2.5 | 53.4% | 2 | LOSS |
| DET@PHI | DET +3 | 55.8% | 5 | LOSS |
| KC@DEN | DEN +4.5 | 53.0% | 2 | WIN |
| DET@PHI | UNDER 47 | 53.4% | 2 | WIN |
| SEA@LAR | OVER 48.5 | 54.6% | 4 | LOSS |
| NYJ@NE | UNDER 43.5 | 53.4% | 3 | WIN |
| NYJ@NE | JAMIEN SHERWOOD OVER 4.5 TACKLES | 56.8% | 6 | LOSS |
| PHI@GB | PHI +1.5 | 54.8% | 4 | WIN |
| PHI@GB | UNDER 45.5 | 52.4% | 2 | WIN |
| PHI@GB | SAQUON BARKLEY OVER 17.5 RUSH ATT | 56.6% | 6 | WIN |
| PHI@GB | JOSH JACOBS UNDER 42.5 1ST HALF RUSH + REC YDS | 54.4% | 4 | LOSS |
| NO@CAR | CAR -5 | 55.4% | 5 | LOSS |
| BAL@MIN | BAL -3.5 | 57.6% | 7 | WIN |
| CLE@NYJ | CLE -130 | 65.4% | 7 | LOSS |
| NYG@CHI | CHI -4.5 | 55.2% | 5 | LOSS |
| NE@TB | TB -2 | 56.1% | 6 | LOSS |
| LAR@SF | LAR -5.5 | 53.3% | 2 | WIN |
| JAC@HOU | UNDER 38 | 54.8% | 5 | LOSS |
| ARI@SEA | TREY MCBRIDE OVER 9 RECV TARGETS | 55.8% | 5 | WIN |
| DET@WAS | TERRION ARNOLD OVER 4.5 TACKLES + ASSTS | 56.8% | 6 | LOSS |
| JAC@HOU | TRAVIS ETIENNE UNDER 74.5 RUSH + REC YDS | 54.4 | 4 | LOSS |
| LV@DEN | DANIEL CARLSON OVER 1.5 FIELD GOALS | 55.2% | 5 | LOSS |
| LV@DEN | COURTLAND SUTTON OVER 53.5 RECV YDS | 54.2% | 4 | LOSS |
| LV@DEN | RILEY MOSS OVER 4.5 TACKLE + ASST | 54.8% | 4 | WIN |
| LV@DEN | UNDER 43 | 53.4% | 2 | WIN |
| ARI@DAL | BUDDA BAKER OVER 7.5 TACKLES + ASSTS | 54.4% | 4 | WIN |
| ARI@DAL | GEORGE PICKENS OVER 4.5 RECEPTIONS | 56.6% | 6 | WIN |
| DEN@HOU | WIL LUTZ OVER 1.5 MADE FIELD GOALS | 54.2% | 3 | LOSS |
| SEA@WAS | SEA -3 | 56.7% | 6 | WIN |
| IND@PIT | IND -3 | 56.8% | 6 | LOSS |
| LAC@TEN | LAC -9.5 | 56.2% | 6 | LOSS |
| CHI@CIN | CHI -2.5 | 52.6% | 2 | WIN |
| SEA@WAS | OVER 48 | 52.9% | 2 | WIN |
| SEA@WAS | JAYDEN DANIELS OVER 20.5 PASS COMP | 56.7% | 6 | LOSS |
| JAC@LV | JAC -140 | 64.2% | 7 | WIN |
| NO@LAR | LAR -14 | 55.0% | 4 | WIN |
| DEN@HOU | HOU -1.5 | 54.2% | 3 | LOSS |
| CAR@GB | GB -12.5 | 55.4% | 5 | LOSS |
| SF@NYG | NYG +2.5 | 56.1% | 5 | LOSS |
| BAL@MIA | TUA TAGOVAILOA UNDER 0.5 INT | 55.3% | 5 | LOSS |
| TB@NO | TB -3.5 | 52.3% | 1 | WIN |
| GB@PIT | GB -2.5 | 52.3% | 1 | WIN |
| SF@HOU | SF +2.5 | 56.0% | 6 | LOSS |