Must Bet NFL Week 15 AI Picks, Predictions & Hidden Market Mistakes
Updated: 2025-12-07T08:00:00-06:02By Remi at Leans.AI — AI picks for ATS, ML, OU & props
Our Week 15 NFL computer picks combine play-by-play data, simulations, and market moves to surface ATS, moneyline, over/under, and player prop edges. Below you’ll find AI predictions with confidence ratings, plus best bets and buy-to numbers.
Pro tip: prices move. Refresh before kickoff to catch new edges and verify current odds.
Best Week 15
NFL AI Player Prop
WEEK 15 NFL Computer Picks (ATS, ML, O/U)
WEEK 15 NFL Odds
WEEK 15 NFL ODDS COMPARISON
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Live AI NFL Picks — Week 15
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL schedule.
Below is our current AI NFL picks Week 15, NFL computer picks Week 15, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| NFL | 10/30 | BAL@MIA | UNLOCK THIS PICK | 5 |
EXECUTIVE
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| NFL | 10/30 | BAL@MIA | UNLOCK THIS PICK | 1 |
INTEL
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Week 15 Storylines & Angles
Offense vs. Defense Mismatches
Quarterback & Scheme Trends
Travel, Rest & Situational Spots
Weather & Late-Breaking Injuries
Check up to the minute weather forecasts here.
Credit: USA TODAY/IMAGN
NFL Week 15 Best Bets & AI Prop Picks
Week 15 NFL Best Bet – Pro Tips
Note Price sensitivity: We crunch numbers, not teams. If the market moves beyond our
buy-to number, expected value decays and the edge can disappear. Respect the price.
Unit sizing (1–10): Our unit scale reflects model signal strength, injury/variance risk,
and current line availability. Higher units = stronger conviction, not permission to over-expose.
Staking & correlation: Default stake scales with edge and volatility. Avoid stacking too many
correlated outcomes (same game, same player ladder) unless you deliberately size down.
Closing-Line Value (CLV): Beating the close consistently is a quality signal—even across small samples.
Track your entry vs. close; it’s the most reliable feedback loop for long-term profitability.
Week 15 Line Movement
Every pick includes a playable to line or price (e.g., -2.5, Over 44.5, +115). If you can’t get that number or better, consider passing or reducing stake. Lines move—check back for live updates in our Live AI Picks stream and see quick notes in Odds & Line Movement.
Note – all of our data is for informational purposes only and not a recommendation as to whether or how to wager.
Line Movement Tracker — Week 15
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
|
–
–
|
-420
+330
|
-7.5 (-115)
+7.5 (-105)
|
O 51.5 (-105)
U 51.5 (-115)
|
|
|
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
|
–
–
|
-142
+120
|
-2.5 (-110)
+2.5 (-110)
|
O 50.5 (-120)
U 50.5 (-102)
|
|
|
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
|
–
–
|
-158
+134
|
-3 (-115)
+3 (-105)
|
O 50.5 (-104)
U 50.5 (-118)
|
|
|
Nov 2, 2025 1:00PM EST
Carolina Panthers
Green Bay Packers
11/2/25 1PM
Panthers
Packers
|
–
–
|
+700
-1100
|
+13.5 (-108)
-13.5 (-112)
|
O 43.5 (-115)
U 43.5 (-105)
|
|
|
Nov 2, 2025 1:00PM EST
Atlanta Falcons
New England Patriots
11/2/25 1PM
Falcons
Patriots
|
–
–
|
+190
-230
|
+5.5 (-115)
-5.5 (-105)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Nov 2, 2025 1:00PM EST
Denver Broncos
Houston Texans
11/2/25 1PM
Broncos
Texans
|
–
–
|
+106
-124
|
+1.5 (-108)
-1.5 (-112)
|
O 40.5 (-105)
U 40.5 (-115)
|
|
|
Nov 2, 2025 1:00PM EST
San Francisco 49ers
New York Giants
11/2/25 1PM
49ers
Giants
|
–
–
|
-146
+126
|
-2.5 (-115)
+2.5 (-105)
|
O 48.5 (-115)
U 48.5 (-105)
|
|
|
Nov 2, 2025 1:00PM EST
Los Angeles Chargers
Tennessee Titans
11/2/25 1PM
Chargers
Titans
|
–
–
|
-480
+370
|
-9.5 (-110)
+9.5 (-110)
|
O 43.5 (-105)
U 43.5 (-115)
|
|
|
Nov 2, 2025 1:00PM EST
Minnesota Vikings
Detroit Lions
11/2/25 1PM
Vikings
Lions
|
–
–
|
+370
-480
|
+8.5 (-108)
-8.5 (-112)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 2, 2025 4:05PM EST
New Orleans Saints
Los Angeles Rams
11/2/25 4:05PM
Saints
Rams
|
–
–
|
+730
-1150
|
+14.5 (-115)
-14.5 (-105)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
|
Nov 2, 2025 4:05PM EST
Jacksonville Jaguars
Las Vegas Raiders
11/2/25 4:05PM
Jaguars
Raiders
|
–
–
|
-158
+134
|
-3 (-105)
+3 (-115)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
|
Nov 2, 2025 4:25PM EST
Kansas City Chiefs
Buffalo Bills
11/2/25 4:25PM
Chiefs
Bills
|
–
–
|
-134
+114
|
-1.5 (-114)
+1.5 (-106)
|
O 52.5 (-105)
U 52.5 (-115)
|
|
|
Nov 2, 2025 8:20PM EST
Seattle Seahawks
Washington Commanders
11/2/25 8:20PM
Seahawks
Commanders
|
–
–
|
-166
+140
|
-3 (-110)
+3 (-110)
|
O 47.5 (-112)
U 47.5 (-108)
|
|
|
Nov 3, 2025 8:15PM EST
Arizona Cardinals
Dallas Cowboys
11/3/25 8:15PM
Cardinals
Cowboys
|
–
–
|
+128
-152
|
+2.5 (-104)
-2.5 (-118)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Nov 6, 2025 8:15PM EST
Las Vegas Raiders
Denver Broncos
11/6/25 8:15PM
Raiders
Broncos
|
–
–
|
+370
-480
|
+9.5 (-115)
-9.5 (-105)
|
O 42.5 (-120)
U 42.5 (-102)
|
|
|
Nov 9, 2025 9:30AM EST
Atlanta Falcons
Indianapolis Colts
11/9/25 9:30AM
Falcons
Colts
|
–
–
|
+290
-360
|
+7 (-105)
-7 (-115)
|
O 48.5 (-108)
U 48.5 (-112)
|
|
|
Nov 9, 2025 1:00PM EST
New Orleans Saints
Carolina Panthers
11/9/25 1PM
Saints
Panthers
|
–
–
|
+166
-198
|
+3.5 (-105)
-3.5 (-115)
|
O 39.5 (-115)
U 39.5 (-105)
|
|
|
Nov 9, 2025 1:00PM EST
New England Patriots
Tampa Bay Buccaneers
11/9/25 1PM
Patriots
Buccaneers
|
–
–
|
+108
-126
|
+1.5 (-108)
-1.5 (-112)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
|
Nov 9, 2025 1:00PM EST
New York Giants
Chicago Bears
11/9/25 1PM
Giants
Bears
|
–
–
|
+142
-172
|
+3 (-104)
-3 (-118)
|
O 45.5 (-105)
U 45.5 (-115)
|
|
|
Nov 9, 2025 1:00PM EST
Buffalo Bills
Miami Dolphins
11/9/25 1PM
Bills
Dolphins
|
–
–
|
-420
+330
|
-8.5 (-105)
+8.5 (-115)
|
O 49.5 (-105)
U 49.5 (-115)
|
How Our AI Picks Work
Our NFL model blends play-by-play efficiency, drive-level simulations, and market-aware priors. We incorporate injury reports, rest/travel effects, and weather to adjust team strength and total expectations. Each game is simulated thousands of times to produce fair prices; the displayed Model Edge % is the gap between our fair price and the current market.
Market-aware: incorporates liquidity windows and closing-line efficiency.
Context-adjusted: rest days, travel, altitude, tempo, and scheme tendencies.
Transparency: we show confidence, edges, and track CLV and ROI.
Remi, our AI sports genius, has been pouring over tons of data from every past game across NFL week 15 using recursive machine learning to impressive AI to analyze the data to a single cover probability.
The Algorithm has been most fixated on the growing weight human bettors regularly put on coaching factors between a visitors team going up against a possibly deflated home teams. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
FAQ — Week 15 NFL
Where can I see Week 15 NFL AI picks by bet type?
Right on this page. We publish Week 15 NFL computer picks organized by Against the Spread (ATS), Moneyline, Totals (Over/Under), and Player Props so you can jump straight to the markets you bet most.
What are the “best bets” for Week 15 according to the model?
“Best bets” are our highest-confidence Week 15 NFL AI picks based on fair price vs. current odds. Look for larger Model Edge % and higher confidence stars; those signal stronger value at widely available prices.
How are your Week 15 NFL computer picks generated?
We combine play-by-play data, drive-level simulations, and market-aware priors. The model produces a fair price for each side/total/prop, then compares it to live odds to surface Week 15 edges worth betting.
How often do you update Week 15 NFL AI picks?
Throughout the week and up to kickoff. As injuries, weather, and prices move, our projections refresh—so check back closer to game time for the most accurate read on Week 15 value.
Do your Week 15 picks include player props like anytime TD or yardage?
Yes. Our Week 15 NFL AI picks include props such as anytime touchdown, rushing/receiving yards, passing yards, attempts, and more when markets are liquid and pricing shows an edge.
Do you post same-game parlay (SGP) ideas for Week 15?
When correlations and prices justify it, we highlight SGP concepts tied to our Week 15 AI edges—think side/total anchored to complementary player props. We only list combos when expected value remains positive.
What do Model Edge % and units mean?
Model Edge % is the gap between our fair price and the current line/price. Units (1–10) summarize signal quality, volatility, and line availability for Week 15 NFL AI picks.
What are “buy-to” numbers, and what if the line moves?
“Buy-to” is the furthest playable number before expected value disappears. If the market pushes past that level, the Week 15 pick may no longer qualify—wait for a better price or skip the bet.
Do you track closing-line value (CLV) and ROI for Week 15?
Yes. We grade results against widely available prices at publish time and monitor CLV to gauge process quality. You’ll also find recent record and ROI to keep Week 15 performance transparent.
How should I size bets on Week 15 NFL AI picks?
Scale stake size with edge and volatility. Larger Model Edge % and higher confidence typically merit slightly larger positions, but avoid over-exposure to correlated outcomes within the same game.
Are teasers viable for Week 15?
Sometimes. Teasers can make sense around key numbers when totals and pricing conditions are favorable. If our Week 15 read flags teaser value, we’ll note the recommended legs and limits.
How do injuries, weather, and travel impact Week 15 NFL picks?
Materially. The model adjusts team strength, pace, and totals for late scratches, snap-count news, wind/rain/cold thresholds, altitude, rest, and travel. Those inputs can change edges close to kickoff.
Where can I compare Week 15 NFL odds to shop the best number?
Use your preferred odds screen or our odds links from this page. Shopping lines is essential—Model Edge % is calculated against available prices, and the best number often determines long-term ROI.
Can I get alerts when new Week 15 NFL AI picks post or when lines move to buy-to?
Yes. Enable notifications or subscribe for alerts so you catch new Week 15 AI picks, notable line moves, and updates to buy-to ranges before the market fully adjusts.
Past NFL AI Picks
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| TB@NO | TB -3.5 | 52.3% | 1 | WIN |
| GB@PIT | GB -2.5 | 52.3% | 1 | WIN |
| SF@HOU | SF +2.5 | 56.0% | 6 | LOSS |
| NYG@PHI | NYG +7.5 | 53.9% | 3 | LOSS |
| BUF@CAR | CAR +7.5 | 54.2% | 3 | LOSS |
| DAL@DEN | DAL +3.5 | 55.0% | 4 | LOSS |
| MIA@ATL | MIA +7 | 54.3% | 4 | WIN |
| CLE@NE | CLE +7 | 56.8% | 6 | LOSS |
| TB@NO | BAKER MAYFIELD OVER 15.5 RUSH YDS | 56.6% | 6 | LOSS |
| MIN@LAC | JUSTIN HERBERT PASS ATT UNDER 35.5 | 55.5% | 5 | WIN |
| TB@DET | TB +6.5 | 54.4% | 4 | LOSS |
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |