Away Team
Record 89-73
Last 5 2-3 last five
ATS 79-83-0 ATS
Road 43-38 road
Standings
MLB Game Preview
Schedule
First Pitch Countdown
8:40:53
Start Time 10:00 PM EST
Date September 29, 2026
Venue Petco Park
Where To Watch NBC Sports Network
Where To Stream Peacock
Season Series Chicago leads 5-1.

San Diego enters Game 1 as a modest home favorite behind Michael King, but Chicago owns a 5-1 season-series edge and elite defense, creating real tension around a low 7 to 7.5 total.

Home Team
Record 91-71
Last 5 4-1 last five
ATS 94-68-0 ATS
Home 51-30 home
Analysis Updated: 7:02 AM ET
Injuries Checked: 7:02 AM ET
Odds Updated: 1:04 PM ET

Betting Snapshot

Spread
SD +1.5
Open: SD -1.5
Market Steady

Spread Movement

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Odds Updated: 9/29 1:04 PM ET
Moneyline
SD -124
Open: SD -121
Favorite Taking Support

Moneyline Movement

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Odds Updated: 9/29 1:04 PM ET
Total
7.5
Open: 7.5
Total Steady

Total Movement

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Odds Updated: 9/29 1:04 PM ET

Best Free Prop Pick

FREE PROP
Matthew Boyd Over 12.5 Outs
King struck out at least five in two of his final three starts, supporting over 4.5 strikeouts. Chicago struck out 34 times over its last five, supporting King over 4.5 strikeouts. As San Diego's Game 1 ace, King's expected starter workload supports over 4.5 strikeouts.

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Odds Comparison Center

Shop for the best lines in one place.

Best Home Spread
DraftKings | SD +1.5
Best Home Moneyline
DraftKings | SD -124
Best Over Line
BetRivers | 7
Best Away Spread
FanDuel | CHC +1.5
Best Away Moneyline
BetOnline.ag | CHC +117
Best Under Line
FanDuel | 7.5
Updated 1:04 PM ET
Sportsbook Spread Moneyline Total
FanDuelCHC +1.5
SD -1.5
CHC +108
SD -126
O 7.5
U 7.5
DraftKingsCHC -1.5
SD +1.5
CHC +103
SD -124
O 7.5
U 7.5
BetMGMCHC +1.5
SD -1.5
CHC +105
SD -125
O 7.5
U 7.5
BetRiversCHC +1.5
SD -1.5
CHC +110
SD -132
O 7
U 7
FanaticsCHC +1.5
SD -1.5
CHC +110
SD -130
O 7.5
U 7.5
BovadaCHC +1.5
SD -1.5
CHC +108
SD -130
O 7.5
U 7.5
BetOnline.agCHC +1.5
SD -1.5
CHC +117
SD -129
O 7.5
U 7.5
LowVig.agCHC +1.5
SD -1.5
CHC +117
SD -129
O 7.5
U 7.5
MyBookie.agCHC +1.5
SD -1.5
CHC +106
SD -124
O 7.5
U 7.5
BetUSCHC +1.5
SD -1.5
CHC +116
SD -127
O 7.5
U 7.5
CaesarsCHC +1.5
SD -1.5
CHC +107
SD -125
O 7.5
U 7.5

Injury Report

Chicago's Kevin Gausman is being monitored after injuring his non-throwing shoulder, while Alex Bregman has returned as a DH after facial fractures and Dansby Swanson is back from an oblique injury. San Diego remains without Casey Mize, Lucas Giolito, Joe Musgrove and high-leverage reliever Jeremiah Estrada. Jason Adam has recently returned from a shoulder strain, while Miguel Andujar appears ready after a wrist fracture but faces a roster decision.

Key Players

Chicago
Pete Crow-Armstrong
Finished with 45 homers, 41 steals, 107 RBIs and a .942 OPS.
San Diego
Manny Machado
Led San Diego with 30 homers and 91 RBIs over 158 games.

Key Matchup Edge

San Diego's clearest betting edge is run prevention at home: King finished with a 3.21 ERA, the Padres went 51-30 at Petco Park, and their bullpen posted a 3.53 ERA. In a game carrying a 7 to 7.5 total, clean early innings could make the favorite's late-inning depth especially valuable.

3 Things to Watch

  • King's strikeout efficiency through first two trips
  • Bregman's role after facial fractures
  • Padres bullpen bridge to Mason Miller

Betting Breakdown

San Diego opens this NL Wild Card rematch with home field, the better recent form and Michael King on the mound, which explains a market price around -125 and a total sitting between 7 and 7.5. The Padres finished 91-71, went 51-30 at Petco Park and closed 8-2 over their final 10, while their offense surged to the top of MLB by wRC+ after September began. Chicago counters with the season-series evidence: a 5-1 record against San Diego and a 55-28 scoring edge, plus a defense that led baseball by a wide margin in Statcast value. Matthew Boyd starts for the Cubs after a 10-5, 3.91 ERA season, and the return of Alex Bregman adds another impact bat behind Pete Crow-Armstrong. The matchup is built for tight innings. San Diego has the stronger home profile and bullpen numbers, but Chicago's defensive efficiency, power and prior success against this opponent keep the underdog live if Boyd can match King early.

Chicago Betting Outlook

Chicago arrives 89-73 after an uneven 2-3 final five and a 79-83 run-line season, but the road profile is respectable at 43-38. The stronger case for the Cubs comes from matchup history and run prevention: they won five of six against San Diego and finished with MLB-best Statcast defensive marks. Pete Crow-Armstrong supplies elite power-speed production after a 45-homer, 41-steal season, while Alex Bregman's return from facial fractures immediately restored middle-order thump. Matthew Boyd gets Game 1 after finishing 10-5 with a 3.91 ERA. Chicago's betting path is straightforward: defend, limit free baserunners and force San Diego to win late rather than allowing its September offense to seize control early.

San Diego Betting Outlook

San Diego finished 91-71, went 51-30 at Petco Park and closed 4-1 in its last five, while posting a 94-68 run-line record. The Padres' offense also transformed late, tying for MLB's best wRC+ from the start of September. Manny Machado closed with 30 homers and 91 RBIs, Fernando Tatis Jr. rediscovered his power after the break, and Michael King draws the Game 1 start after a 3.21 ERA and 159 strikeouts in 185 innings. The bullpen posted a 3.53 ERA and is built to shorten postseason games, though Jeremiah Estrada's shoulder absence removes an important leverage arm. San Diego's strongest betting case combines home-field form, King and late-game pitching depth.

Latest Team Buzz

Chicago Cubs vs San Diego Padres FAQ

What is the current spread for Chicago Cubs vs San Diego Padres?

The current home spread is SD +1.5, while the away spread is CHC -1.5.

How far has the spread moved for Chicago Cubs vs San Diego Padres?

The spread opened at SD -1.5 and is now SD +1.5.

What is the current moneyline for Chicago Cubs vs San Diego Padres?

The current moneyline is CHC +103 / SD -124.

How far has the moneyline moved for Chicago Cubs vs San Diego Padres?

The moneyline opened at CHC +101 / SD -121 and is now CHC +103 / SD -124.

What is the current total for Chicago Cubs vs San Diego Padres?

The current total is 7.5.

How far has the total moved for Chicago Cubs vs San Diego Padres?

The total opened at 7.5 and is now 7.5.

Is the market taking the underdog in Chicago Cubs vs San Diego Padres?

Current market signal: Market Steady.

Is the market taking the favorite in Chicago Cubs vs San Diego Padres?

Current market signal: Favorite Taking Support.

Is the total dropping for Chicago Cubs vs San Diego Padres?

Current totals signal: Total Steady.

Is the total rising for Chicago Cubs vs San Diego Padres?

Current totals signal: Total Steady.

Where to watch Chicago Cubs vs San Diego Padres?

You can watch this game on NBC Sports Network. For the latest broadcast details, see Where to Watch.

Where to stream Chicago Cubs vs San Diego Padres?

You can stream this game on Peacock.

What is the best free prop bet for Chicago Cubs vs San Diego Padres?

Matthew Boyd Over 12.5 Outs

What is the biggest matchup edge for Chicago Cubs vs San Diego Padres?

San Diego's clearest betting edge is run prevention at home: King finished with a 3.21 ERA, the Padres went 51-30 at Petco Park, and their bullpen posted a 3.53 ERA. In a game carrying a 7 to 7.5 total, clean early innings could make the favorite's late-inning depth especially valuable.

REMI AI PERFORMANCE

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Chicago Cubs vs. San Diego Padres
Game Date September 29, 2026
Venue Petco Park
RECENT COMPLETED PICKS

AI MLB PAST PICKS

35-16 68.6% WIN
GAME
LEAN
WIN %
UNITS
RESULT
SF@PIT
OVER 8.5
55.3%
5
WIN
TOR@CLE
TOR -115
54.6%
4
WIN
ATL@WAS
ATL -130
55.4%
4
WIN
TOR@CLE
JO ADELL OVER 0.5 HITS
55.4%
5
LOSS
SF@PIT
OVER 7.5
55.9%
5
WIN
SD@CIN
SD -126
55.0%
3
LOSS
NYM@TB
TB -130
54.9%
3
WIN
SF@PIT
JUNG HOO LEE OVER 0.5 HITS
54.2%
4
LOSS
DET@MIN
ROYCE LEWIS UNDER 0.5 RUNS
54.5%
4
LOSS
BAL@COL
BAL -121
54.7%
4
WIN
NYY@LAA
NYY -114
55.1%
5
LOSS
PHI@LAA
UNDER 8
54.7%
4
WIN
COL@ATL
UNDER 8.5
56.3%
6
WIN
BOS@NYY
BOS -112
54.8%
4
LOSS
SEA@TOR
SEA -125
54.6%
4
LOSS
SEA@TOR
GEORGE SPRINGER OVER 0.5 HITS
54.2%
4
WIN
MIA@WAS
OVER 7.5
55.3%
5
WIN
SEA@TOR
TOR -118
54.8%
4
WIN
COL@ATL
GRANT HOLMES OVER 4.5 HITS ALLOWED
54.2%
4
WIN
ARI@SF
ARI -110
54.8%
4
WIN
KC@CLE
CLE -126
54.9%
3
LOSS
ARI@SF
RAFAEL DEVERS OVER 0.5 HITS
54.2%
4
WIN
KC@TOR
KC -106
53.3%
3
WIN
LAD@ATL
ATL -109
53.5%
3
WIN
LAD@ATL
MICHAEL HARRIS II UNDER 1.5 BASES
53.2%
3
WIN
COL@WAS
OVER 8.5
55.8%
5
WIN
CLE@LAA
CLE -130
55.4%
4
WIN
CIN@SF
SAL STEWART OVER 0.5 STRIKEOUTS
54.7%
4
LOSS
KC@TOR
OVER 8.5
56.1%
6
LOSS
BAL@STL
STL -124
55.2%
5
LOSS
CLE@LAA
CLE -131
55.2%
4
WIN
TEX@CHW
EVAN CARTER OVER 0.5 HITS
54.2%
4
WIN
TEX@CHW
OVER 8.5
54.9%
4
WIN
CHC@ARI
CHC -130
55.5%
4
WIN
NYM@CHW
JARED YOUNG OVER 0.5 HITS
54.3%
4
WIN
STL@PHI
OVER 7.5
55.2%
5
WIN
WAS@MIA
OVER 8.5
55.4%
5
LOSS
LAA@TEX
EZEQUIEL DURAN OVER 0.5 HITS
54.2%
4
WIN
STL@PHI
OVER 9
55.8%
5
WIN
TB@BAL
TB -116
54.6%
4
LOSS
STL@PHI
BRANDON MARSH UNDER 0.5 RUNS
55.1%
5
LOSS
PIT@LAD
OVER 8
55.6%
5
WIN
TB@BAL
BAL -124
55.0%
4
WIN
SEA@MIL
DOMINIC CANZONE OVER 0.5 HITS
53.4%
3
WIN
NYY@BAL
UNDER 8
54.0%
4
WIN
NYY@BAL
NYY -116
54.2%
4
WIN
MIA@PHI
JUSTIN CRAWFORD OVER 0.5 HITS
54.4%
4
WIN
SD@NYM
SD -125
55.1%
5
LOSS
MIA@PHI
PHI -121
55.2%
5
WIN
TOR@TB
TAYLOR WALLS OVER 0.5 HITS
54.4%
4
WIN
TOR@TB
TB -126
55.1%
4
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.