Away Team
Record 88-71
Last 5 3-2 last five.
ATS 78-81-0 ATS.
Road 42-36 road.
Standings
MLB Game Preview
Schedule
First Pitch Countdown
5:44:53
Start Time 6:06 PM EST
Date September 25, 2026
Venue Fenway Park
Where To Watch NESN
Where To Stream NESN 360
Season Series Series tied 0-0.

Boston enters the nightcap after losing four of five, while Chicago brings the stronger season offense into a near pick'em market. David Peterson's recent surge and Brayan Bello's 11-strikeout gem tighten a total sitting at 6.5.

Home Team
Record 85-74
Last 5 1-4 last five.
ATS 74-85-0 ATS.
Home 39-39 home.
Analysis Updated: 6:35 AM ET.
Injuries Checked: 6:34 AM ET.
Odds Updated: 7:19 AM ET

Betting Snapshot

Spread
BOS +1.5
Open: BOS +1.5
Market Steady

Spread Movement

Loading line history...
Odds Updated: 9/25 7:19 AM ET
Moneyline
BOS -101
Open: BOS +102
Favorite Taking Support

Moneyline Movement

Loading line history...
Odds Updated: 9/25 7:19 AM ET
Total
6.5
Open: 6.5
Total Steady

Total Movement

Loading line history...
Odds Updated: 9/25 7:19 AM ET

Best Free Prop Pick

FREE PROP
Pedro Ramirez Over 0.5 Total Bases
Seiya Suzuki Over 0.5 total bases: six-game hit streak and .476 season slugging. Seiya Suzuki Over 0.5 total bases: Bello has allowed 119 hits in 112.1 innings. Seiya Suzuki Over 0.5 total bases: projected top-two lineup role maximizes nightcap plate appearances.

This page gives you one free prop. Upgrade for premium sides, totals, more props, and the full daily AI board.

Unlock Premium AI Picks

Odds Comparison Center

Shop for the best lines in one place.

Best Home Spread
FanDuel | BOS +1.5
Best Home Moneyline
FanDuel | BOS +106
Best Over Line
FanDuel | 6.5
Best Away Spread
FanDuel | CHC -1.5
Best Away Moneyline
BetOnline.ag | CHC -116
Best Under Line
FanDuel | 6.5
Updated 7:19 AM ET
Sportsbook Spread Moneyline Total
FanDuelCHC -1.5
BOS +1.5
CHC -124
BOS +106
O 6.5
U 6.5
DraftKingsCHC -1.5
BOS +1.5
CHC -120
BOS -101
O 6.5
U 6.5
BetMGMCHC -1.5
BOS +1.5
CHC -120
BOS +100
O 6.5
U 6.5
BetRiversCHC -1.5
BOS +1.5
CHC -117
BOS -103
O 6.5
U 6.5
FanaticsCHC -1.5
BOS +1.5
CHC -120
BOS +100
O 6.5
U 6.5
BovadaCHC -1.5
BOS +1.5
CHC -126
BOS +106
O 6.5
U 6.5
BetOnline.agCHC -1.5
BOS +1.5
CHC -116
BOS +105
O 6.5
U 6.5
LowVig.agCHC -1.5
BOS +1.5
CHC -116
BOS +105
O 6.5
U 6.5
MyBookie.agCHC -1.5
BOS +1.5
CHC -120
BOS +102
O 6.5
U 6.5
CaesarsCHC -1.5
BOS +1.5
CHC -120
BOS +103
O 6.5
U 6.5

Injury Report

Chicago is monitoring Alex Bregman after multiple facial fractures from a foul ball; his availability remains the biggest lineup question, while Kevin Gausman's shoulder issue removes another rotation option. Boston remains without Garrett Crochet because of shoulder inflammation, and Willson Contreras has missed six straight while struggling to grip a bat with a bruised right hand. Ceddanne Rafaela returned after recent hamstring tightness, but his movement still bears watching.

Key Players

Chicago
David Peterson
Allowed one run over six innings with seven strikeouts in each of his last two starts.
Boston
Brayan Bello
Struck out 11 over eight one-run innings against Tampa Bay last start.

Key Matchup Edge

Chicago's clearest edge is lineup depth. The Cubs average about 5.3 runs per game compared with Boston's 4.3, and Pete Crow-Armstrong anchors the stronger power profile. Boston has also scored no more than two runs in five straight. If Peterson limits traffic again, Chicago can make Bello pitch with little margin for error before the bullpens take over.

3 Things to Watch

  • Peterson's recent seven-strikeout form
  • Boston's stalled late-season offense
  • Nightcap bullpen usage after Game 1

Betting Breakdown

The 6:05 p.m. ET nightcap arrives with both clubs postseason-bound and still caring about position. Chicago enters at 88-71 with a 42-36 road mark and the more productive offense, while Boston is 85-74, 39-39 at Fenway and coming off a five-game stretch in which it never scored more than two runs. The starting-pitching form is much tighter than the season ERAs suggest. David Peterson has allowed one run over six innings with seven strikeouts in each of his last two starts, and Brayan Bello just held Tampa Bay to one run across eight innings with 11 strikeouts. That combination helps explain a 6.5 total in a near pick'em market. The wrinkle is the doubleheader. Bullpen availability, lineup rest and late scratches from Game 1 can reshape the best angle quickly. Chicago's deeper run-production profile gives it more ways to create separation, but Boston's best path is another deep Bello outing that limits exposure to its relief corps.

Chicago Betting Outlook

Chicago brings an 88-71 record and 42-36 road mark into Fenway after clinching a Wild Card berth, but its run-line profile has been less convincing at 78-81 overall and 4-6 over the last 10. The offense remains the main selling point, with Pete Crow-Armstrong supplying 45 homers and 107 RBIs while Seiya Suzuki carries a six-game hitting streak. David Peterson is also trending up at the right time, allowing one run in six innings with seven strikeouts in each of his last two starts. Alex Bregman's facial injury removes or limits an important right-handed bat, so Chicago's supporting hitters and doubleheader lineup choices matter more than usual in the nightcap.

Boston Betting Outlook

Boston is 85-74 but only 39-39 at Fenway, and its recent run production is the immediate concern. The Red Sox have lost four of five and scored no more than two runs in every game of that stretch, contributing to a 3-7 run-line record over their last 10. Brayan Bello gives them a strong reset point after eight innings of one-run ball with 11 strikeouts against Tampa Bay. His ability to work deep is especially valuable in the second game of a doubleheader. Offensively, Willson Contreras' bruised hand has kept a key on-base threat sidelined, while Ceddanne Rafaela's recent hamstring tightness adds another variable. Boston needs cleaner early contact to avoid chasing Chicago late.

Latest Team Buzz

Chicago Cubs vs Boston Red Sox FAQ

What is the current spread for Chicago Cubs vs Boston Red Sox?

The current home spread is BOS +1.5, while the away spread is CHC -1.5.

How far has the spread moved for Chicago Cubs vs Boston Red Sox?

The spread opened at BOS +1.5 and is now BOS +1.5.

What is the current moneyline for Chicago Cubs vs Boston Red Sox?

The current moneyline is CHC -120 / BOS -101.

How far has the moneyline moved for Chicago Cubs vs Boston Red Sox?

The moneyline opened at CHC -123 / BOS +102 and is now CHC -120 / BOS -101.

What is the current total for Chicago Cubs vs Boston Red Sox?

The current total is 6.5.

How far has the total moved for Chicago Cubs vs Boston Red Sox?

The total opened at 6.5 and is now 6.5.

Is the market taking the underdog in Chicago Cubs vs Boston Red Sox?

Current market signal: Market Steady.

Is the market taking the favorite in Chicago Cubs vs Boston Red Sox?

Current market signal: Favorite Taking Support.

Is the total dropping for Chicago Cubs vs Boston Red Sox?

Current totals signal: Total Steady.

Is the total rising for Chicago Cubs vs Boston Red Sox?

Current totals signal: Total Steady.

Where to watch Chicago Cubs vs Boston Red Sox?

You can watch this game on NESN. For the latest broadcast details, see Where to Watch.

Where to stream Chicago Cubs vs Boston Red Sox?

You can stream this game on NESN 360.

What is the best free prop bet for Chicago Cubs vs Boston Red Sox?

Pedro Ramirez Over 0.5 Total Bases

What is the biggest matchup edge for Chicago Cubs vs Boston Red Sox?

Chicago's clearest edge is lineup depth. The Cubs average about 5.3 runs per game compared with Boston's 4.3, and Pete Crow-Armstrong anchors the stronger power profile. Boston has also scored no more than two runs in five straight. If Peterson limits traffic again, Chicago can make Bello pitch with little margin for error before the bullpens take over.

REMI AI PERFORMANCE

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Chicago Cubs vs. Boston Red Sox
Game Date September 25, 2026
Venue Fenway Park
RECENT COMPLETED PICKS

AI MLB PAST PICKS

35-16 68.6% WIN
GAME
LEAN
WIN %
UNITS
RESULT
SF@PIT
OVER 8.5
55.3%
5
WIN
TOR@CLE
TOR -115
54.6%
4
WIN
ATL@WAS
ATL -130
55.4%
4
WIN
TOR@CLE
JO ADELL OVER 0.5 HITS
55.4%
5
LOSS
SF@PIT
OVER 7.5
55.9%
5
WIN
SD@CIN
SD -126
55.0%
3
LOSS
NYM@TB
TB -130
54.9%
3
WIN
SF@PIT
JUNG HOO LEE OVER 0.5 HITS
54.2%
4
LOSS
DET@MIN
ROYCE LEWIS UNDER 0.5 RUNS
54.5%
4
LOSS
BAL@COL
BAL -121
54.7%
4
WIN
NYY@LAA
NYY -114
55.1%
5
LOSS
PHI@LAA
UNDER 8
54.7%
4
WIN
COL@ATL
UNDER 8.5
56.3%
6
WIN
BOS@NYY
BOS -112
54.8%
4
LOSS
SEA@TOR
SEA -125
54.6%
4
LOSS
SEA@TOR
GEORGE SPRINGER OVER 0.5 HITS
54.2%
4
WIN
MIA@WAS
OVER 7.5
55.3%
5
WIN
SEA@TOR
TOR -118
54.8%
4
WIN
COL@ATL
GRANT HOLMES OVER 4.5 HITS ALLOWED
54.2%
4
WIN
ARI@SF
ARI -110
54.8%
4
WIN
KC@CLE
CLE -126
54.9%
3
LOSS
ARI@SF
RAFAEL DEVERS OVER 0.5 HITS
54.2%
4
WIN
KC@TOR
KC -106
53.3%
3
WIN
LAD@ATL
ATL -109
53.5%
3
WIN
LAD@ATL
MICHAEL HARRIS II UNDER 1.5 BASES
53.2%
3
WIN
COL@WAS
OVER 8.5
55.8%
5
WIN
CLE@LAA
CLE -130
55.4%
4
WIN
CIN@SF
SAL STEWART OVER 0.5 STRIKEOUTS
54.7%
4
LOSS
KC@TOR
OVER 8.5
56.1%
6
LOSS
BAL@STL
STL -124
55.2%
5
LOSS
CLE@LAA
CLE -131
55.2%
4
WIN
TEX@CHW
EVAN CARTER OVER 0.5 HITS
54.2%
4
WIN
TEX@CHW
OVER 8.5
54.9%
4
WIN
CHC@ARI
CHC -130
55.5%
4
WIN
NYM@CHW
JARED YOUNG OVER 0.5 HITS
54.3%
4
WIN
STL@PHI
OVER 7.5
55.2%
5
WIN
WAS@MIA
OVER 8.5
55.4%
5
LOSS
LAA@TEX
EZEQUIEL DURAN OVER 0.5 HITS
54.2%
4
WIN
STL@PHI
OVER 9
55.8%
5
WIN
TB@BAL
TB -116
54.6%
4
LOSS
STL@PHI
BRANDON MARSH UNDER 0.5 RUNS
55.1%
5
LOSS
PIT@LAD
OVER 8
55.6%
5
WIN
TB@BAL
BAL -124
55.0%
4
WIN
SEA@MIL
DOMINIC CANZONE OVER 0.5 HITS
53.4%
3
WIN
NYY@BAL
UNDER 8
54.0%
4
WIN
NYY@BAL
NYY -116
54.2%
4
WIN
MIA@PHI
JUSTIN CRAWFORD OVER 0.5 HITS
54.4%
4
WIN
SD@NYM
SD -125
55.1%
5
LOSS
MIA@PHI
PHI -121
55.2%
5
WIN
TOR@TB
TAYLOR WALLS OVER 0.5 HITS
54.4%
4
WIN
TOR@TB
TB -126
55.1%
4
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.