Cardinals vs. Cubs
FREE MLB AI Predictions
September 28, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 28, 2025
Start Time: 3:20 PM EST​
Venue: ​
Cubs Record:
Cardinals Record:
OPENING ODDS
STL Moneyline:
CHC Moneyline:
STL Spread:
CHC Spread:
Over/Under:
STL
Betting Trends
CHC
Betting Trends
MATCHUP TRENDS
STL vs. CHC
Best Prop Bet
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St. Louis vs Chicago AI Prediction:
Free MLB Betting Insights for 9/28/25
Cardinals AI Preview
Credit: USA TODAY/IMAGN
Cubs AI Preview
Cardinals vs. Cubs FREE Prop Pick
AI algorithm Remi is pouring through tons of data on each line. In fact, anytime the Cardinals and Cubs play there’s always several intriguing trends to key in on. Not to mention games played at in Sep can often follow normal, predictable patterns.
St. Louis vs. Chicago MLB AI Pick
Remi, our AI sports wizard, has been pouring over mountains of data from every angle between the Cardinals and Cubs and using recursive machine learning and impressive AI to analyze the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the growing weight emotional bettors often put on Chicago’s strength factors between a Cardinals team going up against a possibly healthy Cubs team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.
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