Cardinals vs. Cubs
FREE MLB AI Predictions
September 27, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 27, 2025
Start Time: 2:20 PM EST​
Venue: ​
Cubs Record:
Cardinals Record:
OPENING ODDS
STL Moneyline:
CHC Moneyline:
STL Spread:
CHC Spread:
Over/Under:
STL
Betting Trends
CHC
Betting Trends
MATCHUP TRENDS
STL vs. CHC
Best Prop Bet
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MLB ODDS COMPARISON
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St. Louis vs Chicago AI Prediction:
Free MLB Betting Insights for 9/27/25
Cardinals AI Preview
Credit: USA TODAY/IMAGN
Cubs AI Preview
Cardinals vs. Cubs FREE Prop Pick
Remi is pouring through tons of datapoints on each team. In fact, anytime the Cardinals and Cubs play there’s always several intriguing observations to key in on. Not to mention games played at in Sep almost always follow normal, predictable betting trends.
St. Louis vs. Chicago MLB AI Pick
Remi, our AI sports wizard, has been pouring over mountains of data from every simulation between the Cardinals and Cubs and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.
Remi has been most fixated on the growing weight human bettors regularly put on player performance factors between a Cardinals team going up against a possibly healthy Cubs team. We’ve found the true game analytics might reflect a slight lean against one Vegas line in particular.
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