Orioles vs. Yankees
Prediction, Odds & Props
Sep 27 | MLB AI Picks
Updated: 2025-09-25T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Baltimore Orioles head to Yankee Stadium on September 27, 2025, to face the New York Yankees in a matchup that feels like a crossroads: Baltimore seeks to prove its growth, while New York fights to keep pace in the AL East. With much of the playoff picture still unsettled, the stakes are genuine even in late-season rivalry play.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 27, 2025
Start Time: 1:05 PM EST
Venue: Yankee Stadium
Yankees Record: (92-68)
Orioles Record: (75-85)
OPENING ODDS
BAL Moneyline: +190
NYY Moneyline: -233
BAL Spread: +1.5
NYY Spread: -1.5
Over/Under: 9
BAL
Betting Trends
- When playing on the road this season, the Orioles have struggled to consistently cover the spread, especially against teams with deeper pitching staffs and bullpen depth.
NYY
Betting Trends
- The Yankees, especially at home, have been more reliable in covering the spread, thanks to a potent offense and quality starting pitching that often gives them early edges.
MATCHUP TRENDS
- In head-to-head matchups, totals have tended toward the “over” when both teams bring their full offense to play, particularly when the Orioles’ bullpen is taxed—so bettors should keep an eye on in-game momentum and bullpen usage.
BAL vs. NYY
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: P. Goldschmidt under 6.5 Fantasy Score.
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Baltimore vs New York Prediction & Odds:
Free MLB Betting Insights for 9/27/25
On the other side, the Yankees return home looking to tighten their grip on their playoff standing, energized by one of the deepest lineups in the majors, with Aaron Judge, Giancarlo Stanton, and Juan Soto capable of turning games with one swing. Pitching will be a key separator; New York’s ability to extend its starters into the middle innings and bridge the gap to a rested bullpen gives them an edge over an Orioles squad that often leans too heavily on relief arms. The game is also layered with strategic matchups: how Orioles manager Brandon Hyde deploys his bullpen against the Yankees’ power bats, how Boone balances aggression with patience in his lineup decisions, and whether Baltimore’s speed and situational hitting can neutralize New York’s big-inning potential. Ultimately, this contest shapes up as a test of maturity for the Orioles against the established firepower of the Yankees, and while Baltimore has the tools to make it a fight, New York’s home-field advantage, stronger depth, and playoff-tested roster make them the team to beat in what promises to be a tense and entertaining clash under the bright lights of the Bronx.
O'Neill goes yard. pic.twitter.com/RTvTq94xJo
— Baltimore Orioles (@Orioles) September 27, 2025
Baltimore Orioles MLB Preview
The Baltimore Orioles enter Yankee Stadium on September 27, 2025, with a lot more at stake than just another regular-season game, as they look to prove they can compete toe-to-toe with one of the most storied franchises in baseball while also solidifying their identity as an organization that is no longer just rebuilding but actively trying to contend, and the away setting only makes that mission more challenging but also more meaningful, as victories in hostile environments often serve as defining moments for young teams. Baltimore has made strides in recent years, leaning heavily on the development of its farm system and the emergence of young stars who have injected life into both the lineup and the fan base, and while this core has shown flashes of brilliance, the inconsistency that often plagues developing rosters still lingers, especially in areas like bullpen management, late-game execution, and sustained offensive pressure against quality pitching staffs. Their path to victory against New York requires several things to fall in place: first, their starting pitcher must work efficiently and avoid falling into early trouble, as the Yankees’ lineup is not only deep but thrives on punishing pitchers who allow free passes or make mistakes up in the zone; second, the Orioles’ defense must be sharp, because in Yankee Stadium one error or a poorly judged fly ball can change the momentum of an entire game, and third, their bats must deliver timely hits, particularly with runners in scoring position, an area that has too often betrayed them in close games this season.
The Orioles’ offense, when clicking, can be explosive—anchored by middle-order hitters who combine raw power with the ability to grind out at-bats—but against a team with multiple front-line starters and a rested bullpen, they will need to balance aggression with patience, working counts to elevate pitch totals and forcing the Yankees’ manager into earlier-than-planned bullpen calls. Road games in the Bronx also test mental toughness as much as physical execution; the Orioles will need to block out the noise, stay disciplined, and play within themselves, because chasing big moments often backfires when facing a team that thrives on pressure. The bullpen remains the biggest question mark—if their starter cannot provide at least six solid innings, the relief corps will be stretched thin, and that has historically been where the Yankees seize control late, turning one-run games into comfortable wins. Baltimore must also be opportunistic, perhaps using aggressive base running, situational bunts, or hit-and-run plays to keep New York off balance, because trading home runs swing-for-swing with the Yankees is rarely a sustainable formula. Ultimately, this away game represents a chance for Baltimore to measure their growth: a strong performance here, regardless of outcome, shows they can hang with the big boys, but a collapse would underscore how much further they need to go before being taken seriously as consistent contenders. The Orioles have the talent to be dangerous on any given night, but the key will be discipline, execution, and composure—three things that must align perfectly if they hope to steal a win in one of baseball’s toughest environments.

Credit: USA TODAY/IMAGN
New York Yankees MLB Preview
The New York Yankees step into their home game against the Baltimore Orioles on September 27, 2025, with both confidence and pressure, as they know Yankee Stadium provides them a clear advantage but also that every late-season contest carries heightened implications for postseason positioning, and in this matchup they will aim to flex the depth, discipline, and star power that have long defined their identity as one of baseball’s premier franchises. At home the Yankees have been a different team, with their offense often firing on all cylinders thanks to the intimidating presence of Aaron Judge, Juan Soto, and Giancarlo Stanton in the heart of the order, a trio that forces opposing pitchers to work carefully and often leads to early runs or elevated pitch counts that make life easier for the rest of the lineup, which has been bolstered by complementary contributors who extend at-bats and provide balance with situational hitting. New York’s formula for success is built on controlling the game early, as their starting pitchers are tasked with keeping the Orioles’ bats quiet long enough for the offense to grab a lead, and when that works, it allows the bullpen to take over in the later innings, where the Yankees typically thrive, leveraging power arms and matchup specialists to shut down rallies before they can build. Their defensive discipline has also been a strength, with solid play across the diamond minimizing mistakes and ensuring pitchers are supported, which is critical against an Orioles team looking to capitalize on any slip.
From a strategic standpoint, manager Aaron Boone will likely look to exploit Baltimore’s relative lack of bullpen depth by being patient at the plate, grinding out long at-bats, and forcing their starter into early jams, knowing that once the Orioles turn to relief, the Yankees’ lineup has the patience and power to pile on runs quickly. The energy of the Bronx crowd adds another dimension, as opposing teams often find themselves rattled by the intensity, and the Yankees players clearly feed off that momentum, especially in tight late-game situations where every pitch is magnified. New York also benefits from its ability to win in multiple ways—whether it’s a slugfest fueled by home runs, a tight pitchers’ duel where their bullpen locks things down, or a situational game that requires small-ball tactics, they have the versatility to adapt, and that makes them difficult to beat in their own park. For this particular matchup, the Yankees will be especially focused on limiting mistakes, jumping on Baltimore pitching early, and keeping the pressure on through all nine innings, knowing that letting a young team like the Orioles hang around could invite trouble. More than anything, the Yankees will want to make a statement with a convincing performance, reminding the league that they remain the standard-bearers in the AL East, and that when the lights are brightest at Yankee Stadium, they have both the pedigree and the firepower to deliver. In many ways, this home contest is as much about reinforcing their dominance as it is about securing another win, and the Yankees will enter the field determined to do both.
You be the Judge. pic.twitter.com/rFJrqICBCj
— New York Yankees (@Yankees) September 27, 2025
Baltimore vs. New York Prop Picks (AI)
Baltimore vs. New York Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Orioles and Yankees and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.
Interestingly enough, the data has been most focused on the linear correlation of factor human bettors often put on player performance factors between a Orioles team going up against a possibly improved Yankees team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Baltimore vs New York picks, computer picks Orioles vs Yankees, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Orioles Betting Trends
When playing on the road this season, the Orioles have struggled to consistently cover the spread, especially against teams with deeper pitching staffs and bullpen depth.
Yankees Betting Trends
The Yankees, especially at home, have been more reliable in covering the spread, thanks to a potent offense and quality starting pitching that often gives them early edges.
Orioles vs. Yankees Matchup Trends
In head-to-head matchups, totals have tended toward the “over” when both teams bring their full offense to play, particularly when the Orioles’ bullpen is taxed—so bettors should keep an eye on in-game momentum and bullpen usage.
Baltimore vs. New York Game Info
What time does Baltimore vs New York start on September 27, 2025?
Baltimore vs New York starts on September 27, 2025 at 1:05 PM EST.
Where is Baltimore vs New York being played?
Venue: Yankee Stadium.
What are the opening odds for Baltimore vs New York?
Spread: New York -1.5
Moneyline: Baltimore +190, New York -233
Over/Under: 9
What are the records for Baltimore vs New York?
Baltimore: (75-85) | New York: (92-68)
What is the AI best bet for Baltimore vs New York?
Remi's searched hard and found the best prop for this matchup: P. Goldschmidt under 6.5 Fantasy Score.. Prices move—always shop for the best number.
What are Baltimore vs New York trending bets?
In head-to-head matchups, totals have tended toward the “over” when both teams bring their full offense to play, particularly when the Orioles’ bullpen is taxed—so bettors should keep an eye on in-game momentum and bullpen usage.
What are Baltimore trending bets?
BAL trend: When playing on the road this season, the Orioles have struggled to consistently cover the spread, especially against teams with deeper pitching staffs and bullpen depth.
What are New York trending bets?
NYY trend: The Yankees, especially at home, have been more reliable in covering the spread, thanks to a potent offense and quality starting pitching that often gives them early edges.
Where can I find AI Picks for Baltimore vs New York?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Baltimore vs. New York Odds
AI algorithm Remi is pouring through loads of data points on each line. In fact, anytime the Baltimore vs New York trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable patterns.
Baltimore vs New York Opening Odds
BAL Moneyline:
+190 NYY Moneyline: -233
BAL Spread: +1.5
NYY Spread: -1.5
Over/Under: 9
Baltimore vs New York Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
|
–
–
|
+100
-120
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-1.5 (+175)
+1.5 (-215)
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O 7 (-105)
U 7 (-115)
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Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
|
–
–
|
+100
-118
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-1.5 (+172)
+1.5 (-210)
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O 7.5 (-110)
U 7.5 (-110)
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Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
|
–
–
|
+136
-162
|
+1.5 (-160)
-1.5 (+130)
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O 7.5 (-120)
U 7.5 (-102)
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Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
|
–
–
|
+110
-130
|
pk
pk
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Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+108
-126
|
pk
pk
|
O 7 (-135)
U 7 (+115)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Baltimore Orioles vs. New York Yankees on September 27, 2025 at Yankee Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |