Cardinals vs. Cubs
FREE MLB AI Predictions
September 26, 2025



Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 26, 2025

Start Time: 2:20 PM EST​

Venue: ​

Cubs Record:

Cardinals Record:

OPENING ODDS

STL Moneyline:

CHC Moneyline:

STL Spread:

CHC Spread:

Over/Under:

STL
Betting Trends

CHC
Betting Trends

MATCHUP TRENDS

STL vs. CHC
Best Prop Bet

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
295-209
VAULT
NET UNITS
(INCL VIG)
+417.7
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
EXECUTIVE
VS. SPREAD
1521-1315
EXECUTIVE
NET UNITS
(INCL VIG)
+318
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$31,804

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

St. Louis vs Chicago AI Prediction:
Free MLB Betting Insights for 9/26/25

Cardinals AI Preview

 St. Louis vs Chicago AI Prediction: Free MLB Betting Insights for Sep 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cubs AI Preview

Cardinals vs. Cubs FREE Prop Pick

AI algorithm Remi is pouring through tons of stats on each team. In fact, anytime the Cardinals and Cubs play there’s always several intriguing angles to key in on. Not to mention games played at in Sep can often follow normal, predictable betting trends.

St. Louis vs. Chicago MLB AI Pick

Remi Robot Icon

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Cardinals and Cubs and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

The Algorithm has been most keyed in on the linear correlation of factor knucklehead sportsbettors often put on Chicago’s strength factors between a Cardinals team going up against a possibly tired Cubs team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.