Cardinals vs. Cubs
FREE MLB AI Predictions
September 26, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 26, 2025
Start Time: 2:20 PM EST​
Venue: ​
Cubs Record:
Cardinals Record:
OPENING ODDS
STL Moneyline:
CHC Moneyline:
STL Spread:
CHC Spread:
Over/Under:
STL
Betting Trends
CHC
Betting Trends
MATCHUP TRENDS
STL vs. CHC
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MLB ODDS COMPARISON
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VS. SPREAD
295-209
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+417.7
NET PROFIT
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$100/UNIT
$41,768
VS. SPREAD
1521-1315
NET UNITS
(INCL VIG)
+318
NET PROFIT
(INCL VIG)
$100/UNIT
$31,804
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St. Louis vs Chicago AI Prediction:
Free MLB Betting Insights for 9/26/25
Cardinals AI Preview

Credit: USA TODAY/IMAGN
Cubs AI Preview
Cardinals vs. Cubs FREE Prop Pick
AI algorithm Remi is pouring through tons of stats on each team. In fact, anytime the Cardinals and Cubs play there’s always several intriguing angles to key in on. Not to mention games played at in Sep can often follow normal, predictable betting trends.
St. Louis vs. Chicago MLB AI Pick

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Cardinals and Cubs and using recursive machine learning and impressive AI to analyze the data to a single cover probability.
The Algorithm has been most keyed in on the linear correlation of factor knucklehead sportsbettors often put on Chicago’s strength factors between a Cardinals team going up against a possibly tired Cubs team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
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