Tigers vs. Guardians
FREE MLB AI Predictions
September 23, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 23, 2025
Start Time: 6:40 PM EST​
Venue: ​
Guardians Record:
Tigers Record:
OPENING ODDS
DET Moneyline:
CLE Moneyline:
DET Spread:
CLE Spread:
Over/Under:
DET
Betting Trends
CLE
Betting Trends
MATCHUP TRENDS
DET vs. CLE
Best Prop Bet
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
NET UNITS (INCL VIG)
NET PROFIT (INCL VIG) $100/UNIT
NET UNITS (INCL VIG)
NET PROFIT (INCL VIG) $100/UNIT
AI SPORTS PICK PRODUCTS
Create a Free Account
‘Create an Account’ to Get Remi’s Picks Today. Remi Finds New Picks
Remi calculates the probability a team will cover the line. Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Detroit vs Cleveland AI Prediction:
Free MLB Betting Insights for 9/23/25
Tigers AI Preview
Credit: USA TODAY/IMAGN
Guardians AI Preview
Tigers vs. Guardians FREE Prop Pick
Remi is pouring through mountains of stats on each player. In fact, anytime the Tigers and Guardians play there’s always several intriguing angles to key in on. Not to mention games played at in Sep can often follow normal, predictable patterns.
Detroit vs. Cleveland MLB AI Pick
Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Tigers and Guardians and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
Remi has been most keyed in on the growing weight human bettors regularly put on coaching factors between a Tigers team going up against a possibly deflated Guardians team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.