Padres vs. Sox
FREE MLB AI Predictions
September 21, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 21, 2025
Start Time: 2:10 PM EST​
Venue: ​
Sox Record:
Padres Record:
OPENING ODDS
SD Moneyline:
CHW Moneyline:
SD Spread:
CHW Spread:
Over/Under:
SD
Betting Trends
CHW
Betting Trends
MATCHUP TRENDS
SD vs. CHW
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VS. SPREAD
295-209
NET UNITS
(INCL VIG)
+417.7
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
VS. SPREAD
1521-1315
NET UNITS
(INCL VIG)
+318
NET PROFIT
(INCL VIG)
$100/UNIT
$31,804
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San Diego vs Chicago White AI Prediction:
Free MLB Betting Insights for 9/21/25
Padres AI Preview

Credit: USA TODAY/IMAGN
Sox AI Preview
Padres vs. Sox FREE Prop Pick
AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the Padres and Sox play there’s always several intriguing angles to key in on. Not to mention games played at in Sep rarely follow normal, predictable betting trends.
San Diego vs. Chicago White MLB AI Pick

Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Padres and Sox and using recursive machine learning and industry leading AI to examine the data to a single cover probability.
The Algorithm has been most fixated on the linear correlation of emphasis human bettors tend to put on Chicago White’s strength factors between a Padres team going up against a possibly strong Sox team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
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