Yankees vs. Orioles
FREE MLB AI Predictions
September 21, 2025



Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 21, 2025

Start Time: 1:35 PM EST​

Venue: ​

Orioles Record:

Yankees Record:

OPENING ODDS

NYY Moneyline:

BAL Moneyline:

NYY Spread:

BAL Spread:

Over/Under:

NYY
Betting Trends

BAL
Betting Trends

MATCHUP TRENDS

NYY vs. BAL
Best Prop Bet

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
295-209
VAULT
NET UNITS
(INCL VIG)
+417.7
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
EXECUTIVE
VS. SPREAD
1521-1315
EXECUTIVE
NET UNITS
(INCL VIG)
+318
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$31,804

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

New York vs Baltimore AI Prediction:
Free MLB Betting Insights for 9/21/25

Yankees AI Preview

 New York vs Baltimore AI Prediction: Free MLB Betting Insights for Sep 21. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Orioles AI Preview

Yankees vs. Orioles FREE Prop Pick

Remi is pouring through tons of data on each player. In fact, anytime the Yankees and Orioles play there’s always several intriguing trends to key in on. Not to mention games played at in Sep rarely follow normal, predictable betting trends.

New York vs. Baltimore MLB AI Pick

Remi Robot Icon

Remi, our AI sports algorithm, has been pouring over tons of data from every past game between the Yankees and Orioles and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.

Remi has been most keyed in on the growing emphasis emotional bettors often put on player performance factors between a Yankees team going up against a possibly tired Orioles team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.