Brewers vs. Cardinals
FREE MLB AI Predictions
September 21, 2025
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 21, 2025
Start Time: 2:15 PM EST​
Venue: ​
Cardinals Record:
Brewers Record:
OPENING ODDS
MIL Moneyline:
STL Moneyline:
MIL Spread:
STL Spread:
Over/Under:
MIL
Betting Trends
STL
Betting Trends
MATCHUP TRENDS
MIL vs. STL
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MLB ODDS COMPARISON
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VS. SPREAD
295-209
NET UNITS
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+417.7
NET PROFIT
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$100/UNIT
$41,768
VS. SPREAD
1521-1315
NET UNITS
(INCL VIG)
+318
NET PROFIT
(INCL VIG)
$100/UNIT
$31,804
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Milwaukee vs St. Louis AI Prediction:
Free MLB Betting Insights for 9/21/25
Brewers AI Preview

Credit: USA TODAY/IMAGN
Cardinals AI Preview
Brewers vs. Cardinals FREE Prop Pick
AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Brewers and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at in Sep almost always follow normal, predictable patterns.
Milwaukee vs. St. Louis MLB AI Pick

Remi, our AI sports genius, has been pouring over tons of data from every angle between the Brewers and Cardinals and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Remi has been most watching on the trending emphasis human bettors tend to put on St. Louis’s strength factors between a Brewers team going up against a possibly healthy Cardinals team. It appears the true game analytics might reflect a slight lean against one Vegas line specifically.
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