Padres vs Mets Prediction — AI Finds CAN'T MISS MLB Lines & Props (Sep 17)
Updated: 2025-09-15T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres and the New York Mets meet on September 17, 2025, in a matchup that brings together two National League clubs looking to strengthen their positions as the season nears its final stretch. With both teams featuring deep lineups and pitching talent, this contest could hinge on which side manages to execute better in high-leverage moments.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 17, 2025
Start Time: 7:10 PM EST
Venue: Citi Field
Mets Record: (78-73)
Padres Record: (82-69)
OPENING ODDS
SD Moneyline: -106
NYM Moneyline: -113
SD Spread: -1.5
NYM Spread: +1.5
Over/Under: 7.5
SD
Betting Trends
- The Padres have been inconsistent against the spread on the road, with strong pitching performances often offset by streaky offensive production.
NYM
Betting Trends
- The Mets have performed better at Citi Field against the spread, often leveraging their home-field advantage and bullpen strength to cover in close games.
MATCHUP TRENDS
- Matchups between these two clubs have frequently been tight, with several contests decided by one or two runs and trending toward the under thanks to quality starting pitching. Bettors may see value in backing a close, low-scoring contest given both teams’ ability to suppress runs when their rotations are in form.
SD vs. NYM
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: F. Lindor over 0.5 Total Bases.
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San Diego vs New York Prediction & Odds:
Free MLB Betting Insights for 9/17/25
Kodai Senga has grown into the ace of their rotation, capable of dominating with strikeouts and precision, while veterans like José Quintana provide reliable innings to bridge into a bullpen that has become a genuine strength, with Edwin Díaz reclaiming his role as one of the most feared closers in baseball. The Mets have relied on this balance of offense and pitching to keep them competitive, though they too have endured stretches of streaky offense, often leaving Alonso and Lindor to shoulder more than their share of the scoring load. What makes this matchup so compelling is the contrast in styles: San Diego’s reliance on star power and power hitting against New York’s more disciplined, situationally sharp brand of baseball that thrives on manufacturing runs and preventing mistakes. Betting trends and recent results suggest this could be a tight, low-scoring contest, as both teams are capable of shutting down elite lineups when their rotations deliver, and given the history between them, games have often come down to slim margins and late-inning execution. For the Padres, the formula for victory lies in striking early against New York’s starters and avoiding high-leverage bullpen duels late, while the Mets will look to use their depth and bullpen reliability to outlast San Diego in a game where every run will carry added significance. Ultimately, this showdown feels like a microcosm of both teams’ seasons: talent and potential on both sides, but only one will emerge proving they can execute with the precision needed in the final sprint toward October.
Final. pic.twitter.com/oDUrhA74HW
— San Diego Padres (@Padres) September 17, 2025
San Diego Padres MLB Preview
The San Diego Padres enter their September 17, 2025 matchup against the New York Mets at Citi Field with both urgency and unpredictability hanging over them, as they continue to navigate a season that has showcased immense individual talent but struggled to find the consistency needed to cement themselves as true contenders. Fernando Tatis Jr. remains the centerpiece of their lineup, combining speed, power, and athleticism to spark rallies and change games with one swing or daring baserunning play, while Manny Machado continues to provide veteran steadiness, offering timely hits and reliable defense at third base. Xander Bogaerts has added another layer of depth with his ability to hit for average and drive in runs, giving the Padres a formidable trio that can carry the offense when firing together, yet the supporting cast has too often gone quiet in key stretches, creating frustrating lulls that leave the team unable to capitalize on opportunities. Pitching remains a double-edged sword for San Diego, with Yu Darvish and Joe Musgrove capable of shutting down elite lineups when they are at their best, but durability concerns and a bullpen that has repeatedly faltered under pressure have undermined what could otherwise be a strength.
Relievers like Robert Suarez and Steven Wilson have shown flashes, but the unit as a whole has struggled to consistently protect slim leads, making it imperative for starters to go deeper into games to limit exposure. Defensively, the Padres have been serviceable, with Machado’s glove anchoring the infield and Tatis providing versatility, but errors at critical moments have occasionally opened the door for opponents to seize control. On the road, San Diego has not been as sharp against the spread, reflecting their struggles to sustain offense in hostile environments and their reliance on bullpen arms that are less reliable outside of Petco Park. To compete effectively against the Mets, the Padres will need their stars to set the tone offensively, ideally jumping on New York’s pitching early, while also receiving contributions from role players who can lengthen the lineup and prevent opposing pitchers from working around the big bats. Discipline at the plate will be crucial, as the Mets’ staff thrives on forcing hitters into chasing pitches outside the zone, and San Diego cannot afford wasted at-bats if they are to keep pace. For the Padres, this game represents more than just another late-season contest—it is a test of whether their roster can deliver when the margin for error is razor thin, and their ability to execute on the road will go a long way toward shaping their playoff trajectory.

Credit: USA TODAY/IMAGN
New York Mets MLB Preview
The New York Mets host the San Diego Padres on September 17, 2025, at Citi Field with confidence in their ability to protect home turf and continue building momentum as the postseason race intensifies, drawing on a roster that has blended star power, steady pitching, and improving bullpen reliability to stay competitive throughout the grind of the season. Offensively, the Mets are powered by Pete Alonso’s game-changing home run bat, Francisco Lindor’s consistency and leadership, and Brandon Nimmo’s ability to reach base and spark rallies from the leadoff spot, creating a lineup that can both slug its way to victory and manufacture runs with patience and speed. The addition of younger contributors has added energy, while veterans provide the experience needed to handle late-season pressure, and collectively, the offense has delivered enough balance to win both high-scoring and tightly contested games. On the mound, Kodai Senga has established himself as the ace of the staff, using his strikeout arsenal to dominate even the toughest lineups, while José Quintana and other starters have provided steady innings that set the tone and reduce stress on the bullpen.
That bullpen, which has often been a point of concern in past seasons, has emerged as a strength in 2025, led by Edwin Díaz reclaiming his role as one of the most intimidating closers in baseball, supported by setup arms that have grown more comfortable in high-leverage roles. Defensively, the Mets are sound, with Lindor anchoring the infield and Nimmo’s range in center field providing reliability that helps prevent extra bases, an essential element in close games where every mistake matters. At Citi Field, the Mets have been solid against the spread, often thriving in front of their home crowd with the comfort of familiar conditions and the energy of fans pushing them through tense moments. To succeed against the Padres, New York will need to neutralize San Diego’s trio of Tatis, Machado, and Bogaerts, forcing the supporting cast to carry the load while using their pitching depth to keep the stars in check. Offensively, the Mets must continue their disciplined approach, working counts to elevate San Diego’s starters’ pitch counts and targeting a vulnerable bullpen that has struggled to finish games, giving them a prime opportunity to take control in the later innings. With playoff stakes high and their path to October depending on execution, the Mets will look to their stars to lead while relying on the depth and resilience that has carried them through the season, making them well-positioned to deliver another crucial home victory in their pursuit of postseason glory.
A big night for Lindor on Clemente Day 💪@moomooApp | #LGM pic.twitter.com/Ae8HZnyu4B
— New York Mets (@Mets) September 17, 2025
San Diego vs. New York Prop Picks (AI)
San Diego vs. New York Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every angle between the Padres and Mets and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most fixated on the linear correlation of weight emotional bettors often put on coaching factors between a Padres team going up against a possibly healthy Mets team. In reality, the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs New York picks, computer picks Padres vs Mets, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
The Padres have been inconsistent against the spread on the road, with strong pitching performances often offset by streaky offensive production.
Mets Betting Trends
The Mets have performed better at Citi Field against the spread, often leveraging their home-field advantage and bullpen strength to cover in close games.
Padres vs. Mets Matchup Trends
Matchups between these two clubs have frequently been tight, with several contests decided by one or two runs and trending toward the under thanks to quality starting pitching. Bettors may see value in backing a close, low-scoring contest given both teams’ ability to suppress runs when their rotations are in form.
San Diego vs. New York Game Info
What time does San Diego vs New York start on September 17, 2025?
San Diego vs New York starts on September 17, 2025 at 7:10 PM EST.
Where is San Diego vs New York being played?
Venue: Citi Field.
What are the opening odds for San Diego vs New York?
Spread: New York +1.5
Moneyline: San Diego -106, New York -113
Over/Under: 7.5
What are the records for San Diego vs New York?
San Diego: (82-69) | New York: (78-73)
What is the AI best bet for San Diego vs New York?
Remi's searched hard and found the best prop for this matchup: F. Lindor over 0.5 Total Bases.. Prices move—always shop for the best number.
What are San Diego vs New York trending bets?
Matchups between these two clubs have frequently been tight, with several contests decided by one or two runs and trending toward the under thanks to quality starting pitching. Bettors may see value in backing a close, low-scoring contest given both teams’ ability to suppress runs when their rotations are in form.
What are San Diego trending bets?
SD trend: The Padres have been inconsistent against the spread on the road, with strong pitching performances often offset by streaky offensive production.
What are New York trending bets?
NYM trend: The Mets have performed better at Citi Field against the spread, often leveraging their home-field advantage and bullpen strength to cover in close games.
Where can I find AI Picks for San Diego vs New York?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. New York Odds
Remi is pouring through tons of stats on each line. In fact, anytime the San Diego vs New York trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.
San Diego vs New York Opening Odds
SD Moneyline:
-106 NYM Moneyline: -113
SD Spread: -1.5
NYM Spread: +1.5
Over/Under: 7.5
San Diego vs New York Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
|
–
–
|
-155
+130
|
-1.5 (+115)
+1.5 (-140)
|
O 7.5 (+100)
U 7.5 (-120)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. New York Mets on September 17, 2025 at Citi Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |