Padres vs. Mets
Prediction, Odds & Props
Sep 16 | MLB AI Picks
Updated: 2025-09-14T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres travel to Citi Field on September 16, 2025, to face the New York Mets in a matchup with potential postseason implications as both teams remain in the hunt for playoff spots. The Padres lean on their star-studded lineup and improving pitching staff, while the Mets look to protect home field and ride their power bats and deep rotation.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 16, 2025
Start Time: 7:10 PM EST​
Venue: Citi Field​
Mets Record: (77-73)
Padres Record: (82-68)
OPENING ODDS
SD Moneyline: -106
NYM Moneyline: -114
SD Spread: -1.5
NYM Spread: +1.5
Over/Under: 8.5
SD
Betting Trends
- The Padres have been inconsistent against the spread on the road, often winning close games outright but struggling to cover larger run lines when favored. Their ability to cover has been tied closely to the performance of their starting pitchers.
NYM
Betting Trends
- The Mets have been reliable against the spread at Citi Field, particularly when their top starters take the mound, and their offense has shown a knack for delivering in clutch moments at home. They have also covered well in divisional matchups, giving them betting appeal in similar spots.
MATCHUP TRENDS
- Head-to-head, the Padres and Mets have produced tightly contested games, with many matchups staying within one or two runs, making underdog plays attractive. Totals have often leaned toward the under when aces start, but the over has hit in games where bullpens were forced into heavy use.
SD vs. NYM
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Soto over 0.5 Total Bases.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
310-227
NET UNITS
(INCL VIG)
+390.9
NET PROFIT
(INCL VIG)
$100/UNIT
$39,086
VS. SPREAD
1564-1335
NET UNITS
(INCL VIG)
+387.3
NET PROFIT
(INCL VIG)
$100/UNIT
$38,728
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
San Diego vs New York Prediction & Odds:
Free MLB Betting Insights for 9/16/25
The Mets, on the other hand, have built a stronger identity around their rotation, which continues to be their greatest strength, with top starters giving them a chance to win nearly every time they take the mound and a bullpen that has improved significantly compared to recent seasons, turning once-vulnerable late innings into a source of stability. Offensively, New York has relied on a mix of veteran hitters who bring power and experience with younger contributors adding balance, and while they may not have the same star-laden reputation as San Diego, their lineup has proven capable of manufacturing runs in clutch situations, particularly at Citi Field where their bats often find another gear. Defensively, the Mets have played disciplined baseball, minimizing errors and supporting their pitching staff effectively, which has been a key factor in their ability to stay in the thick of the postseason race despite facing a competitive division. From a betting perspective, this game shapes up as another tightly contested battle between the two clubs, with spreads expected to be narrow due to the competitiveness of their head-to-head history, while the total will likely hinge on the starting pitcher matchup, with ace-level performances pushing the under and bullpen exposure creating opportunities for the over. For San Diego, the formula for success is simple but difficult: get strong production from their stars, limit mistakes, and trust their pitching to keep them in the game, while the Mets will look to strike early against a Padres staff that can be vulnerable on the road and rely on their bullpen to hold any late leads. Ultimately, this matchup feels like a microcosm of both clubs’ seasons—San Diego trying to harness its talent into sustained results and New York trying to maximize consistency and execution—and the winner will likely be the team that better executes its identity under playoff-like pressure.
¡Feliz Mes de la Herencia Hispana!
— San Diego Padres (@Padres) September 15, 2025
We are proud to celebrate the achievements and contributions of our Hispanic players, employees, fans, and the San Diego community. pic.twitter.com/JnFDRGvkBj
San Diego Padres MLB Preview
The San Diego Padres arrive at Citi Field on September 16, 2025, knowing that every game carries weight as they continue their push toward October, and they bring with them a roster loaded with big-name talent but also carrying the burden of inconsistency that has defined much of their season. Their offense, on paper, is one of the most dangerous in baseball, with middle-of-the-order bats capable of producing instant offense through both power and timely hitting, yet they have too often alternated between explosive scoring nights and stretches where they struggle to even move runners into scoring position. For this matchup against the Mets’ strong pitching staff, the Padres’ lineup will need to remain disciplined at the plate, working counts and capitalizing on any mistakes, because wasted opportunities will likely be punished against a team that thrives in close, low-scoring games. On the pitching side, San Diego’s starters have the ability to control games, and if they can deliver a quality outing, the Padres’ chances improve significantly, but inconsistency and inefficiency have led to too many early exits that strain a bullpen already known for volatility.
That bullpen has been a major question mark, capable of locking down innings on its best days but just as likely to surrender leads late, and facing a Mets team that excels in clutch situations at home only raises the stakes. Defensively, the Padres have been steady overall, but lapses in execution have cost them in tight contests, and playing clean baseball in a hostile road environment will be crucial to keeping the game within reach. From a betting perspective, San Diego has been a risky play against the spread on the road, often winning outright in tight contests but struggling to cover larger lines when expected to dominate, making them an unpredictable team for backers. To secure a win in New York, the Padres will need their stars to set the tone, their starter to hold the Mets in check long enough for the offense to find its rhythm, and their bullpen to step up in what will almost certainly be a high-pressure situation late. For San Diego, this matchup is less about proving talent and more about proving resilience and consistency, as their ability to deliver in a playoff-like atmosphere against a tough opponent could be a defining moment in their push toward the postseason.

Credit: USA TODAY/IMAGN
New York Mets MLB Preview
The New York Mets enter their September 16, 2025, matchup against the San Diego Padres at Citi Field with the confidence of a team that has established itself as one of the tougher clubs to beat at home, leaning on a formula of strong pitching, timely hitting, and disciplined defense that has kept them firmly in the playoff hunt. Their rotation remains their biggest strength, with frontline starters capable of neutralizing even the most talented lineups, and that advantage will be critical against a Padres roster that can break open games quickly when its stars are locked in. Once the game moves into the later innings, the Mets’ bullpen—long a source of frustration for fans in past seasons—has become a reliable unit, providing depth and stability that allows the team to protect narrow leads with far more consistency than in years prior. Offensively, New York may not always produce gaudy totals, but they have shown a knack for situational hitting, with veterans anchoring the middle of the order and younger players contributing balance and energy, helping them capitalize on scoring opportunities in high-leverage spots.
At Citi Field, their bats often play up, with the comfort of home surroundings and crowd support providing an edge in close games, and that atmosphere has contributed to their strong record against the spread at home this season. Defensively, the Mets have also been sound, avoiding costly mistakes and supporting their pitchers by converting key outs, an often-overlooked element that has allowed their pitching staff to maximize efficiency. From a betting perspective, the Mets have rewarded backers in run line scenarios at home, particularly when their starters deliver quality outings and the bullpen maintains its composure, making them a more trustworthy side than their opponent in this contest. For New York, the keys will be attacking San Diego’s starter early to prevent the Padres from settling into a rhythm, continuing to string together productive at-bats rather than waiting for the long ball, and relying on their pitching depth to close the game once they gain control. With their playoff positioning on the line and every series magnified in mid-September, the Mets will look to treat this matchup not just as another test but as an opportunity to reinforce their identity as a disciplined, balanced, and postseason-ready team capable of thriving under pressure.
Our nominee for the 2025 Roberto Clemente Award: @Lindor12BC! 👏
— New York Mets (@Mets) September 15, 2025
Vote for him to win the league-wide award 🗳️👉 https://t.co/wlJEPzsrp7 pic.twitter.com/4sdaUFnWY8
San Diego vs. New York Prop Picks (AI)
San Diego vs. New York Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Padres and Mets and using recursive machine learning and impressive AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the trending weight human bettors often put on player performance factors between a Padres team going up against a possibly rested Mets team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs New York picks, computer picks Padres vs Mets, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
![]() |
|
MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
![]() |
|
MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
![]() |
|
MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
![]() |
|
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
![]() |
|
MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
![]() |
|
MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
The Padres have been inconsistent against the spread on the road, often winning close games outright but struggling to cover larger run lines when favored. Their ability to cover has been tied closely to the performance of their starting pitchers.
Mets Betting Trends
The Mets have been reliable against the spread at Citi Field, particularly when their top starters take the mound, and their offense has shown a knack for delivering in clutch moments at home. They have also covered well in divisional matchups, giving them betting appeal in similar spots.
Padres vs. Mets Matchup Trends
Head-to-head, the Padres and Mets have produced tightly contested games, with many matchups staying within one or two runs, making underdog plays attractive. Totals have often leaned toward the under when aces start, but the over has hit in games where bullpens were forced into heavy use.
San Diego vs. New York Game Info
What time does San Diego vs New York start on September 16, 2025?
San Diego vs New York starts on September 16, 2025 at 7:10 PM EST.
Where is San Diego vs New York being played?
Venue: Citi Field.
What are the opening odds for San Diego vs New York?
Spread: New York +1.5
Moneyline: San Diego -106, New York -114
Over/Under: 8.5
What are the records for San Diego vs New York?
San Diego: (82-68) Â |Â New York: (77-73)
What is the AI best bet for San Diego vs New York?
Remi's searched hard and found the best prop for this matchup: J. Soto over 0.5 Total Bases.. Prices move—always shop for the best number.
What are San Diego vs New York trending bets?
Head-to-head, the Padres and Mets have produced tightly contested games, with many matchups staying within one or two runs, making underdog plays attractive. Totals have often leaned toward the under when aces start, but the over has hit in games where bullpens were forced into heavy use.
What are San Diego trending bets?
SD trend: The Padres have been inconsistent against the spread on the road, often winning close games outright but struggling to cover larger run lines when favored. Their ability to cover has been tied closely to the performance of their starting pitchers.
What are New York trending bets?
NYM trend: The Mets have been reliable against the spread at Citi Field, particularly when their top starters take the mound, and their offense has shown a knack for delivering in clutch moments at home. They have also covered well in divisional matchups, giving them betting appeal in similar spots.
Where can I find AI Picks for San Diego vs New York?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. New York Odds
AI algorithm Remi is pouring through mountains of data points on each line. In fact, anytime the San Diego vs New York trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.
San Diego vs New York Opening Odds
SD Moneyline:
-106 NYM Moneyline: -114
SD Spread: -1.5
NYM Spread: +1.5
Over/Under: 8.5
San Diego vs New York Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
|
–
–
|
-103
-120
|
-1.5 (+180)
+1.5 (-235)
|
O 7 (-108)
U 7 (-118)
|
|
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
|
–
–
|
-104
-118
|
-1.5 (+175)
+1.5 (-230)
|
O 7.5 (-113)
U 7.5 (-113)
|
|
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
|
–
–
|
+140
-175
|
+1.5 (-175)
-1.5 (+133)
|
O 7.5 (-117)
U 7.5 (-109)
|
|
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
|
–
–
|
+108
-131
|
pk
pk
|
|
|
Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+114
-126
|
pk
pk
|
O 7 (-134)
U 7 (+117)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. New York Mets on September 16, 2025 at Citi Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
   LEAN |    %WIN |    UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |