Yankees vs. Sox
Prediction, Odds & Props
Sep 13 | MLB AI Picks

Updated: 2025-09-11T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Yankees visited Fenway Park and came away with a 4-1 win over the Boston Red Sox, paced by Aaron Judge’s 362nd career home run and six no-hit innings from Luis Gil. While the Yankees kept momentum in their favor, Boston looks to respond and stop a streak of tough games in this perennial rivalry.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 13, 2025

Start Time: 4:10 PM EST​

Venue: Fenway Park​

Sox Record: (81-67)

Yankees Record: (82-65)

OPENING ODDS

NYY Moneyline: -138

BOS Moneyline: +116

NYY Spread: -1.5

BOS Spread: +1.5

Over/Under: 8.5

NYY
Betting Trends

  • In their last 10 matchups versus the Red Sox, the Yankees have gone 3-7 against the run line — meaning they’ve struggled to cover when expectations favor them in this rivalry.

BOS
Betting Trends

  • Boston has had better success lately at home and in rivalry games, especially when they’re underdogs or close lines, giving bettors some confidence in backing them in tight spots. (Specific recent run-line success in this matchup is less clearly documented, but their ATS performance at Fenway has been more stable in recent weeks.)

MATCHUP TRENDS

  • Odds for this game have the Yankees as favorites (around –210 moneyline), with the Red Sox as underdogs at about +172. The over/under is set near 9 runs, suggesting expectations for a moderately scoring game. Betting interest leans toward the Yankees to win, but some value for the Red Sox exists for covering due to their recent resilience and Boston’s ability to play better than expectations in close games.

NYY vs. BOS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.

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New York vs Boston Red Prediction & Odds:
Free MLB Betting Insights for 9/13/25

The latest chapter of baseball’s most storied rivalry takes place on September 13, 2025, as the New York Yankees and Boston Red Sox square off at Fenway Park in a game that carries both emotional weight and playoff implications. The Yankees enter this matchup on the heels of a 4-1 victory in the opener, a performance that highlighted the power of Aaron Judge, who blasted his 362nd career home run, and the dominance of Luis Gil, who threw six no-hit innings before exiting. That win extended New York’s momentum and once again showcased their formula for success this season: power in the middle of the order, timely contributions from the supporting cast, and steady starting pitching that sets the tone. The Red Sox, meanwhile, were stifled offensively, producing just two hits in the loss, and their inability to generate rallies against top-tier pitching has become a recurring issue, leaving them desperate to find answers at the plate. Brayan Bello is expected to take the mound for Boston in this one, and his ability to contain the Yankees’ powerful bats will be critical if the Sox hope to even the series. He faces the daunting task of matching up against Max Fried, who gives New York an experienced, steady left-hander capable of navigating pressure games in a hostile environment. The key for Boston will be manufacturing runs—working counts, putting traffic on the bases, and cashing in on scoring chances—because going toe-to-toe with the Yankees’ power is unlikely to succeed.

The Yankees, on the other hand, will once again look to jump on Boston’s starter early, forcing the Red Sox bullpen into action and exploiting any defensive miscues. Their lineup, anchored by Judge but bolstered by consistent bats like Anthony Volpe and Gleyber Torres, has thrived on creating pressure through long at-bats and extra-base hits, and their confidence after Friday night’s win makes them a dangerous opponent in Game 2. Defensively, New York has been sharper than in past years, minimizing errors and giving their pitchers clean innings to work with, a key factor in their rise up the standings. The Red Sox, backed by the energy of Fenway, will need to tap into the rivalry’s intensity to avoid falling into a deeper hole, and their ability to play sound defense while generating any kind of offensive spark will likely determine how competitive they are in this game. From a betting standpoint, the Yankees are deservedly heavy favorites, with oddsmakers installing them around -210 on the moneyline, reflecting both their recent form and their overall talent advantage, while the Red Sox offer underdog value largely based on rivalry unpredictability and home-field advantage. The total is set near nine runs, suggesting expectations for moderate scoring, though both pitching matchups point to the possibility of another tighter, low-scoring affair if Fried and Bello deliver. Ultimately, this game feels like another chance for the Yankees to solidify their dominance, but the Red Sox have the opportunity to remind everyone why this rivalry is never to be overlooked. If Judge stays hot and Fried keeps Boston’s bats cold, the Yankees are primed for another win, but if Bello finds his rhythm and the Sox offense awakens, Fenway could yet again play host to one of those unpredictable rivalry twists that define this historic matchup.

New York Yankees MLB Preview

The New York Yankees enter their September 13, 2025 clash at Fenway Park against the Boston Red Sox riding momentum after a statement win in the series opener, a game that saw Luis Gil flirt with history and Aaron Judge cement his place as the heartbeat of the lineup. This Yankees team has thrived all season on the combination of elite starting pitching, a deep bullpen, and a lineup that features the kind of power and patience few opponents can match, and their performance Friday night was a textbook example of how they overwhelm rivals. Judge’s home run not only added to his career total but also underscored how consistent he’s been at punishing mistakes, while Anthony Volpe and Gleyber Torres have provided timely hitting to keep the offense from being overly reliant on one star. What makes New York particularly dangerous is their ability to score in bunches; they can be quiet for a few innings and then suddenly put up a crooked number thanks to walks, hustle plays, and long balls, often flipping the tone of games in an instant. On the pitching side, Max Fried is expected to take the mound, and his veteran presence brings calm and confidence to a staff that has been remarkably effective at neutralizing big bats in tough environments. The bullpen, one of the league’s most consistent, gives manager Aaron Boone plenty of options late in games, and that versatility allows New York to protect leads with confidence.

Defensively, the Yankees have also improved, reducing errors and giving pitchers the backing they need, a detail that has turned close contests into steady victories. While the team has faced injuries and streaks of inconsistency in past seasons, this version of the Yankees has been resilient, bouncing back from adversity with poise and finding ways to win even when not firing on all cylinders. Their recent ATS trends reflect this dominance, as they’ve consistently covered spreads against division opponents by both winning and doing so convincingly, rewarding bettors who have backed them. Still, rivalry games at Fenway Park always carry a different weight, and the Yankees know the Red Sox will fight hard to avoid a second straight loss, meaning New York will need to stay sharp, avoid early deficits, and continue to apply pressure throughout the lineup. For the Yankees, this game represents more than just another win in the standings; it’s a chance to send a message that the AL East is firmly in their control and that they are built to handle playoff-type atmospheres. If Judge and company deliver another powerful offensive showing, backed by Fried’s command on the mound and a bullpen ready to lock down late innings, New York has every reason to believe they can walk out of Fenway with another victory, strengthening both their confidence and their case as one of baseball’s true juggernauts this season.

The New York Yankees visited Fenway Park and came away with a 4-1 win over the Boston Red Sox, paced by Aaron Judge’s 362nd career home run and six no-hit innings from Luis Gil. While the Yankees kept momentum in their favor, Boston looks to respond and stop a streak of tough games in this perennial rivalry. New York vs Boston Red AI Prediction: Free MLB Betting Insights for Sep 13. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Boston Red Sox MLB Preview

The Boston Red Sox enter their September 13, 2025 matchup against the New York Yankees at Fenway Park with their backs against the wall after being shut down in the opener, producing just two hits in a frustrating loss that highlighted the inconsistency of their offense against elite pitching. Brayan Bello is expected to take the mound in this critical contest, and his role will be pivotal not only in trying to contain the Yankees’ dangerous lineup but also in setting the tone for a Boston team that desperately needs a spark to even the series. Bello has shown flashes of growth and poise, but he’ll have to navigate a deep order that punishes mistakes, meaning his ability to locate his fastball early and mix in his secondary pitches effectively will be key if Boston hopes to keep the game within reach. Offensively, the Red Sox must find a way to string together productive at-bats rather than relying on the occasional solo shot or isolated rally, and that will require discipline at the plate, patience in working counts, and the willingness to take advantage of any defensive miscues New York might offer. Rafael Devers remains the centerpiece of the lineup, but Boston needs help from role players and the supporting cast to keep pressure on Max Fried and force the Yankees’ bullpen into extended work, something they failed to do in the opener.

Fenway Park often provides the Sox with energy and momentum, and feeding off their home crowd could help reignite their bats, particularly if they can get an early lead to put New York on the defensive for once. Defensively, the Red Sox cannot afford lapses, as extra outs have been routinely punished by the Yankees in this rivalry, and sharp play in the infield will be critical to avoid giving away momentum. While their recent ATS record hasn’t been favorable, especially against strong competition, the unpredictability of rivalry games offers them a chance to flip the script if they play with urgency and execute fundamentals. Manager Alex Cora will likely emphasize aggressive base running, small-ball tactics if necessary, and clean situational hitting to maximize every scoring opportunity, knowing that leaving runners stranded is not an option against an opponent that capitalizes so efficiently. For Boston, this game is about pride and survival in a heated division race, and while the Yankees have the advantage on paper, the Red Sox have an opportunity to remind their rivals that Fenway is never an easy place to walk into and win. If Bello can deliver a strong outing, the offense wakes up with timely hitting, and the defense supports without miscues, the Red Sox could turn the rivalry tide and set themselves up for a more competitive series.

New York vs. Boston Red Prop Picks (AI)

Remi is pouring through tons of stats on each team. In fact, anytime the Yankees and Sox play there’s always several intriguing angles to key in on. Not to mention games played at Fenway Park in Sep can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.

New York vs. Boston Red Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every past game between the Yankees and Sox and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

Remi has been most keyed in on the linear correlation of weight knucklehead sportsbettors often put on New York’s strength factors between a Yankees team going up against a possibly deflated Sox team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

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Below is our current AI New York vs Boston Red picks, computer picks Yankees vs Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 BOS@NYY UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 CIN@LAD GET FREE PICK NOW 1
MLB 10/1 BOS@NYY UNLOCK THIS PICK 0 INTEL Locked INTEL
MLB 10/1 BOS@NYY GET FREE PICK NOW 0

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Yankees Betting Trends

In their last 10 matchups versus the Red Sox, the Yankees have gone 3-7 against the run line — meaning they’ve struggled to cover when expectations favor them in this rivalry.

Sox Betting Trends

Boston has had better success lately at home and in rivalry games, especially when they’re underdogs or close lines, giving bettors some confidence in backing them in tight spots. (Specific recent run-line success in this matchup is less clearly documented, but their ATS performance at Fenway has been more stable in recent weeks.)

Yankees vs. Sox Matchup Trends

Odds for this game have the Yankees as favorites (around –210 moneyline), with the Red Sox as underdogs at about +172. The over/under is set near 9 runs, suggesting expectations for a moderately scoring game. Betting interest leans toward the Yankees to win, but some value for the Red Sox exists for covering due to their recent resilience and Boston’s ability to play better than expectations in close games.

New York vs. Boston Red Game Info

New York vs Boston Red starts on September 13, 2025 at 4:10 PM EST.

Spread: Boston Red +1.5
Moneyline: New York -138, Boston Red +116
Over/Under: 8.5

New York: (82-65)  |  Boston Red: (81-67)

Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.. Prices move—always shop for the best number.

Odds for this game have the Yankees as favorites (around –210 moneyline), with the Red Sox as underdogs at about +172. The over/under is set near 9 runs, suggesting expectations for a moderately scoring game. Betting interest leans toward the Yankees to win, but some value for the Red Sox exists for covering due to their recent resilience and Boston’s ability to play better than expectations in close games.

NYY trend: In their last 10 matchups versus the Red Sox, the Yankees have gone 3-7 against the run line — meaning they’ve struggled to cover when expectations favor them in this rivalry.

BOS trend: Boston has had better success lately at home and in rivalry games, especially when they’re underdogs or close lines, giving bettors some confidence in backing them in tight spots. (Specific recent run-line success in this matchup is less clearly documented, but their ATS performance at Fenway has been more stable in recent weeks.)

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York vs. Boston Red Odds

AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the New York vs Boston Red trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

New York vs Boston Red Opening Odds

NYY Moneyline: -138
BOS Moneyline: +116
NYY Spread: -1.5
BOS Spread: +1.5
Over/Under: 8.5

New York vs Boston Red Live Odds

Games PTS ML SPR O/U
Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
+100
-120
-1.5 (+175)
+1.5 (-215)
O 7 (-105)
U 7 (-115)
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
+100
-118
-1.5 (+172)
+1.5 (-210)
O 7.5 (-110)
U 7.5 (-110)
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
+136
-162
+1.5 (-160)
-1.5 (+130)
O 7.5 (-120)
U 7.5 (-102)
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
+110
-130
pk
pk
Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
+108
-126
pk
pk
O 7 (-135)
U 7 (+115)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Yankees vs. Boston Red Sox on September 13, 2025 at Fenway Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS