Dodgers vs. Giants
Prediction, Odds & Props
Sep 13 | MLB AI Picks

Updated: 2025-09-11T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The San Francisco Giants walked off the Los Angeles Dodgers 5-1 in extra innings in the opener, thanks to Patrick Bailey’s grand slam in the 10th, tightening the NL Wild Card race. The Dodgers meanwhile saw another dominant start from Yoshinobu Yamamoto spoiled—he went seven innings, struck out ten, gave up just one run, yet the offense failed to support, sending the game to extras where the bullpen collapsed.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 13, 2025

Start Time: 9:05 PM EST​

Venue: Oracle Park​

Giants Record: (75-72)

Dodgers Record: (82-65)

OPENING ODDS

LAD Moneyline: -123

SF Moneyline: +103

LAD Spread: -1.5

SF Spread: +1.5

Over/Under: 7.5

LAD
Betting Trends

  • Los Angeles has struggled against the spread this season, especially in road games; they are 63-84 ATS on the season.

SF
Betting Trends

  • The Giants have also had a below-.500 ATS mark this season, having gone 67-80 ATS overall. However, in their recent 10 games they’re 7-3 straight-up, indicating some regained momentum.

MATCHUP TRENDS

  • Odds for this game have the Dodgers listed around −123 moneyline, with the Giants +103; Dodgers are about −1.5 on the run line. The over/under is set at 7.5 runs. Public betting is leaning heavily toward the Dodgers. Giants are underdogs but have shown some value recently given their resurgence.

LAD vs. SF
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: M. Chapman over 5.5 Fantasy Score.

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Los Angeles vs San Francisco Prediction & Odds:
Free MLB Betting Insights for 9/13/25

The September 13, 2025 showdown between the Los Angeles Dodgers and the San Francisco Giants comes at a moment when both clubs are feeling the weight of the stretch run, with playoff seeding and Wild Card positioning hanging in the balance, and it delivered immediate fireworks in the opener when Patrick Bailey crushed a walk-off grand slam in the 10th inning to give San Francisco a 5-1 win. For the Giants, it was the kind of emotional jolt they needed, having spent much of the summer battling for consistency, and it showcased both their resilience and their ability to capitalize in pressure moments in front of a roaring home crowd. The Dodgers, meanwhile, were left frustrated, as Yoshinobu Yamamoto delivered one of his best performances of the season with seven dominant innings, striking out 10 and yielding only a single run, yet saw it all undone by an offense that failed to produce in the clutch and a bullpen that faltered under the extra-inning pressure. That dynamic—Dodgers’ strong starting pitching versus Giants’ clutch situational hitting—sets the stage for a fascinating game two, where both teams will look to prove that the opener was no fluke. Los Angeles continues to lean heavily on its big bats like Freddie Freeman and Mookie Betts, though both have experienced stretches of inconsistency that frustrate fans, and they’ll need those stars to deliver with runners in scoring position to avoid another letdown.

San Francisco counters with a balanced offensive approach that isn’t always overwhelming statistically but finds ways to scratch across runs, especially at Oracle Park, where their crowd energy can push them over the line. Defensively, the Giants played clean baseball and avoided giving Los Angeles second chances, while the Dodgers’ usually reliable bullpen has become a concern, especially in tight contests where one bad inning changes everything. Betting markets still favor the Dodgers, listing them narrowly as road favorites with the total set around 7.5 runs, reflecting respect for Yamamoto’s dominance and the Dodgers’ overall talent advantage, but the Giants’ recent 7-3 straight-up run suggests value in their fight to stay alive in the playoff chase. For the Dodgers to win, they must combine strong starting pitching with more aggressive, timely offense early in the game, seizing control before the bullpen becomes a factor; for the Giants, the key is keeping the game tight, getting to the late innings with the crowd behind them, and trusting their lineup to find one or two clutch swings as they did in the opener. This rivalry has always carried weight, but with the Dodgers looking to lock down division control and the Giants trying to claw into October, the stakes add another layer, and it promises a contest where every pitch feels like it could swing the outcome. Ultimately, the Dodgers’ depth and star power make them the safer bet on paper, but the Giants’ momentum and knack for dramatics at home ensure this game will be anything but predictable.

Los Angeles Dodgers MLB Preview

The Los Angeles Dodgers enter their September 13, 2025 matchup against the San Francisco Giants with a mix of urgency and frustration, knowing that while they have the talent and depth to contend for another World Series run, their execution in clutch moments has not always matched the expectations. Friday’s opener was the perfect example of that duality: Yoshinobu Yamamoto was brilliant, carving up the Giants with 10 strikeouts over seven innings and allowing just a single run, yet his masterpiece was wasted when the offense went cold and the bullpen collapsed in extra innings. The Dodgers’ lineup, which features marquee names like Mookie Betts and Freddie Freeman, has been prone to streakiness in recent weeks, producing in bursts but also struggling to push runs across with runners in scoring position, an issue that surfaced again in the opener when they failed to cash in multiple opportunities. Los Angeles has leaned heavily on its pitching all season, and while Yamamoto has delivered ace-level performances, questions linger about the bullpen’s reliability, particularly in tight late-game scenarios where one mistake often proves costly. On the positive side, the Dodgers have not often lost consecutive games this year, showing resilience after setbacks, and manager Dave Roberts has a long track record of guiding his team through these tense rivalry moments with adjustments and lineup flexibility.

The Dodgers also remain one of the league’s most disciplined teams at the plate, ranking among the leaders in walks and on-base percentage, which gives them constant opportunities to generate traffic and wear down opposing pitchers. Defensively, they continue to play clean baseball, minimizing errors and supporting their staff with strong positioning and athletic plays, a hallmark of their success over the past decade. From a betting perspective, Los Angeles remains a slight favorite despite the loss, with the market still trusting their superior roster, deeper rotation, and higher ceiling relative to San Francisco. For the Dodgers to bounce back in this matchup, they must convert baserunners into runs, avoid stranding opportunities, and find a way to take pressure off the bullpen by building a lead that provides breathing room late. If Betts and Freeman can set the tone early and Yamamoto’s rotation mates or another starter can keep the Giants quiet through the middle innings, Los Angeles is well positioned to even the series and reassert its control in the NL West. This is a test of both patience and execution for a team with championship expectations, and while one walk-off loss does not derail their season, responding immediately in game two will send the kind of message that the Dodgers are still the team to beat in this rivalry and beyond.

The San Francisco Giants walked off the Los Angeles Dodgers 5-1 in extra innings in the opener, thanks to Patrick Bailey’s grand slam in the 10th, tightening the NL Wild Card race. The Dodgers meanwhile saw another dominant start from Yoshinobu Yamamoto spoiled—he went seven innings, struck out ten, gave up just one run, yet the offense failed to support, sending the game to extras where the bullpen collapsed.   Los Angeles vs San Francisco AI Prediction: Free MLB Betting Insights for Sep 13. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Francisco Giants MLB Preview

The San Francisco Giants head into their September 13, 2025 matchup against the Los Angeles Dodgers brimming with confidence after one of their most dramatic wins of the season, a 5-1 walk-off victory sealed by Patrick Bailey’s grand slam in the 10th inning that sent Oracle Park into a frenzy. That swing didn’t just win a game; it symbolized the Giants’ resilience and their refusal to let the Dodgers’ ace-level pitching intimidate them, as they found a way to battle back late and seize momentum in a game where Yoshinobu Yamamoto had otherwise kept them quiet. For a team in the thick of the Wild Card hunt, every win carries immense weight, and beating the Dodgers in such a fashion not only gives the Giants a boost in the standings but also strengthens their belief that they can play toe-to-toe with one of baseball’s deepest and most talented rosters. San Francisco has been playing some of its best baseball recently, winning seven of its last ten, and Friday’s win showcased the balance they’ve been able to find: veteran steadiness on the mound with Justin Verlander giving them a chance, a bullpen that held firm until the bats came alive, and a lineup that, while not the most explosive in the league, is opportunistic and capable of big moments when needed.

The Giants’ offense has leaned on players like Bailey, Rafael Devers, and Thairo Estrada to provide consistent production, while complementary pieces have chipped in timely hits that keep pressure on opposing pitchers. Their defense has also been sharp, helping keep games close and preventing opponents from building on small advantages, an underrated factor in their ability to stay competitive in low-scoring contests. Oracle Park itself continues to be a weapon, as the Giants feed off one of the most passionate fan bases in baseball, and when they generate momentum at home, it often snowballs into late-inning dramatics like those seen in the opener. From a betting perspective, San Francisco remains an underdog despite its recent form, reflecting the Dodgers’ talent edge, but the Giants have provided value in this role, especially when they keep games tight into the late innings and give themselves chances to deliver walk-off wins. For the Giants to replicate Friday’s success, they’ll need another strong performance from their starter to neutralize the Dodgers’ big bats, keep the bullpen rested and ready for high-leverage situations, and once again rely on their knack for clutch hitting. If Bailey and Devers can continue sparking the lineup and the rest of the roster keeps grinding out at-bats, San Francisco has every chance to ride its momentum to another statement win. For a team fighting for its postseason life, every game against a rival like Los Angeles is a measuring stick, and the Giants showed they belong in the conversation; now, the challenge is proving it again under the weight of heightened expectations and the Dodgers’ determination to respond.

Los Angeles vs. San Francisco Prop Picks (AI)

Remi is pouring through loads of data on each line. In fact, anytime the Dodgers and Giants play there’s always several intriguing angles to key in on. Not to mention games played at Oracle Park in Sep almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: M. Chapman over 5.5 Fantasy Score.

Los Angeles vs. San Francisco Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every past game between the Dodgers and Giants and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the growing weight knucklehead sportsbettors often put on San Francisco’s strength factors between a Dodgers team going up against a possibly deflated Giants team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles vs San Francisco picks, computer picks Dodgers vs Giants, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 BOS@NYY UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 CIN@LAD GET FREE PICK NOW 1
MLB 10/1 BOS@NYY UNLOCK THIS PICK 0 INTEL Locked INTEL
MLB 10/1 BOS@NYY GET FREE PICK NOW 0

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Dodgers Betting Trends

Los Angeles has struggled against the spread this season, especially in road games; they are 63-84 ATS on the season.

Giants Betting Trends

The Giants have also had a below-.500 ATS mark this season, having gone 67-80 ATS overall. However, in their recent 10 games they’re 7-3 straight-up, indicating some regained momentum.

Dodgers vs. Giants Matchup Trends

Odds for this game have the Dodgers listed around −123 moneyline, with the Giants +103; Dodgers are about −1.5 on the run line. The over/under is set at 7.5 runs. Public betting is leaning heavily toward the Dodgers. Giants are underdogs but have shown some value recently given their resurgence.

Los Angeles vs. San Francisco Game Info

Los Angeles vs San Francisco starts on September 13, 2025 at 9:05 PM EST.

Spread: San Francisco +1.5
Moneyline: Los Angeles -123, San Francisco +103
Over/Under: 7.5

Los Angeles: (82-65)  |  San Francisco: (75-72)

Remi's searched hard and found the best prop for this matchup: M. Chapman over 5.5 Fantasy Score.. Prices move—always shop for the best number.

Odds for this game have the Dodgers listed around −123 moneyline, with the Giants +103; Dodgers are about −1.5 on the run line. The over/under is set at 7.5 runs. Public betting is leaning heavily toward the Dodgers. Giants are underdogs but have shown some value recently given their resurgence.

LAD trend: Los Angeles has struggled against the spread this season, especially in road games; they are 63-84 ATS on the season.

SF trend: The Giants have also had a below-.500 ATS mark this season, having gone 67-80 ATS overall. However, in their recent 10 games they’re 7-3 straight-up, indicating some regained momentum.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles vs. San Francisco Odds

AI algorithm Remi is pouring through mountains of data points on each line. In fact, anytime the Los Angeles vs San Francisco trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.

Los Angeles vs San Francisco Opening Odds

LAD Moneyline: -123
SF Moneyline: +103
LAD Spread: -1.5
SF Spread: +1.5
Over/Under: 7.5

Los Angeles vs San Francisco Live Odds

Games PTS ML SPR O/U
Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
+100
-120
-1.5 (+175)
+1.5 (-215)
O 7 (-105)
U 7 (-115)
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
+100
-118
-1.5 (+172)
+1.5 (-210)
O 7.5 (-110)
U 7.5 (-110)
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
+136
-162
+1.5 (-160)
-1.5 (+130)
O 7.5 (-120)
U 7.5 (-102)
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
+110
-130
pk
pk
Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
+108
-126
pk
pk
O 7 (-135)
U 7 (+115)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Dodgers vs. San Francisco Giants on September 13, 2025 at Oracle Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS