Diamondbacks vs. Giants
Prediction, Odds & Props
Sep 08 | MLB AI Picks
Updated: 2025-09-06T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Arizona Diamondbacks (70–71) visit Oracle Park to face the San Francisco Giants (71–69) on Monday, September 8, 2025, in a late-season clash with division and Wild Card implications for both clubs. Arizona sends Nabil Crismatt to the mound, while the Giants counter with veteran right-hander Logan Webb, setting the stage for a pitching duel that could steer playoff momentum.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 08, 2025
Start Time: 9:45 PM EST
Venue: Oracle Park
Giants Record: (72-71)
Diamondbacks Record: (72-72)
OPENING ODDS
ARI Moneyline: +155
SF Moneyline: -187
ARI Spread: +1.5
SF Spread: -1.5
Over/Under: 7.5
ARI
Betting Trends
- The Diamondbacks enter with a slightly above-average ATS record of 15–13, demonstrating modest success covering the spread.
SF
Betting Trends
- The Giants have a 24–21 ATS record overall this season and have gone 29–27 in home games.
MATCHUP TRENDS
- The betting market positions San Francisco as a clear favorite (around –196), with Arizona at approximately +162 on the moneyline, and a total set at 8 runs, suggesting a close, pitcher-driven contest where one swing or bullpen move could determine both outcome and cover.
ARI vs. SF
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: C. Seymour under 3.5 Pitcher Strikeouts.
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Arizona vs San Francisco Prediction & Odds:
Free MLB Betting Insights for 9/8/25
Their plan against Crismatt will be to jump on hittable fastballs early in counts, as he is most effective when he gets ahead and uses his changeup to induce weak contact, and avoiding extended sequences where he can settle into rhythm will be key. Defensively, San Francisco holds the edge, with a polished infield that has excelled at turning double plays and an outfield that knows how to cover Oracle’s expansive gaps, while Arizona has had issues at times with fielding miscues that extend innings and allow opponents extra chances. The bullpens for both clubs will loom large, as San Francisco’s relief corps has been restructured since losing Randy Rodríguez to Tommy John surgery but still features reliable options capable of handling leverage spots, while Arizona’s bullpen depth has been a question all season, putting added pressure on Crismatt to provide length. From a betting perspective, the Giants’ 24–21 overall ATS record and 29–27 home mark suggest a team that typically takes care of business at Oracle, while the Diamondbacks’ modest 15–13 ATS performance shows they can stay competitive but struggle to consistently cover, particularly against higher-end pitching. Oddsmakers favor San Francisco with a moneyline near –196 and the total set at eight runs, underscoring expectations for a relatively low-scoring affair dominated by pitching and defense rather than slugfests. Ultimately, this game boils down to Webb’s ability to assert control and give the Giants six or seven strong innings versus Crismatt’s capacity to keep Arizona close long enough for their offense to scratch out runs, and with both clubs clinging to playoff relevance, whichever team executes better in high-leverage situations could take a pivotal step forward in the September race.
Final. pic.twitter.com/zH8ZKtuMkM
— Arizona Diamondbacks (@Dbacks) September 7, 2025
Arizona Diamondbacks MLB Preview
For the Diamondbacks, Monday’s September 8 contest at Oracle Park is about resilience, urgency, and proving they can win gritty games against playoff-caliber opponents, and much of that responsibility will rest on the shoulders of Nabil Crismatt, who takes the ball with the task of slowing down a Giants lineup that has been energized by the addition of Rafael Devers and supported by steady veterans like Wilmer Flores. Crismatt has shown flashes of effectiveness when his command is crisp, relying on a changeup and sinker to induce weak contact, but his lack of overpowering stuff means that working ahead in counts and limiting free passes will be absolutely essential if he hopes to navigate through San Francisco’s disciplined bats. Arizona’s offense has not been consistent this season, but there are sparks that give them hope, particularly the return of Gabriel Moreno from injury, whose presence behind the plate stabilizes the defense while also lengthening the batting order, and the contributions of Pavin Smith and other role players who thrive when they’re able to grind pitchers into mistakes. The key for the Diamondbacks will be stringing together quality at-bats, forcing Logan Webb to labor deep into counts, and seizing on the occasional mistake he leaves over the plate, because crooked numbers against an ace-caliber pitcher are rare and must be capitalized upon when the opportunity presents itself.
Defensively, Arizona cannot afford miscues, as Oracle Park’s large gaps reward aggressiveness on the bases, and any defensive lapses could turn singles into doubles and doubles into game-defining rallies. The bullpen remains a question mark, as manager Torey Lovullo has struggled to find reliable middle-inning answers, meaning Crismatt will be asked to give as much length as possible to keep the game within reach before handing the ball to the few trustworthy arms at his disposal. From a betting perspective, the Diamondbacks’ modest 15–13 ATS record shows that while they have managed to stay competitive more often than not, their volatility has made it difficult for bettors to trust them, especially against teams with strong home-field trends like San Francisco. For Arizona, the path to victory is straightforward but difficult: Crismatt must deliver one of his sharper outings of the year by mixing pitches and limiting hard contact, Moreno and Smith must spark the offense with timely production, and the supporting lineup must be disciplined enough to pressure Webb into mistakes while also playing clean defense behind their pitcher. If they execute that blueprint, the Diamondbacks could turn what looks like a tough assignment on paper into a much-needed statement win on the road, proving that even in a season filled with inconsistency, they still have the ability to grind out results and keep themselves alive in the September playoff picture.

Credit: USA TODAY/IMAGN
San Francisco Giants MLB Preview
For the Giants, Monday’s September 8 matchup at Oracle Park against the Diamondbacks is about reinforcing their playoff credentials and continuing to build momentum in front of their home fans, and they will look to their ace Logan Webb to guide them in what projects as a critical contest for the standings. Webb has been the heartbeat of the San Francisco rotation for multiple seasons, known for his ability to command a heavy sinker, mix in sliders with precision, and work deep into games while limiting damage, and against an Arizona lineup that thrives more on contact and situational hitting than pure power, his job will be to attack early in counts and force weak ground balls to his infield. Offensively, the Giants have found new life since the midseason acquisition of Rafael Devers, whose left-handed bat has given them a true middle-of-the-order threat capable of producing big innings with a single swing, while veterans like Wilmer Flores continue to provide consistency and clutch hits in key situations. Against Nabil Crismatt, San Francisco will look to stay aggressive on hittable pitches, avoiding the trap of letting him settle into a rhythm by extending counts, as he is most vulnerable when pressured into high pitch counts and forced to rely too heavily on his changeup.
Defensively, the Giants hold a clear advantage with a polished infield and an outfield that understands the tricky caroms and deep alleys of Oracle Park, an edge that could save runs in a close, low-scoring game where execution matters most. The bullpen, though tested by injuries such as the loss of Randy Rodríguez to Tommy John surgery, has held its own with matchup-based management, and manager Bob Melvin has shown a steady hand in deploying arms in high-leverage situations, something that could become the difference if the game is still tight in the late innings. From a betting perspective, San Francisco’s 24–21 overall ATS mark and a respectable 29–27 record at home highlight their ability to control games in their own ballpark, a pattern that aligns with oddsmakers favoring them as –196 moneyline favorites in this matchup. For the Giants, the recipe for success is straightforward: Webb must continue his ace-level form by neutralizing Arizona’s table-setters, the offense must capitalize on Crismatt’s limited margin for error to build an early lead, and the defense and bullpen must hold steady to prevent late-inning drama. If they deliver on that formula, San Francisco not only strengthens its grip on a postseason berth but also proves once again that Oracle Park remains one of the most difficult venues in baseball for visiting teams to escape with a victory, especially when Webb is on the mound and their lineup is clicking around its new centerpiece in Devers.
Last one in St. Louis
— SFGiants (@SFGiants) September 7, 2025
⌚️: 11:15 a.m. PT
📍: St. Louis, MO
📺: @NBCSGiants
📻: @KNBR | KSFN#SFGiants | @CocaCola pic.twitter.com/UDaC3i95RP
Arizona vs. San Francisco Prop Picks (AI)
Arizona vs. San Francisco Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Diamondbacks and Giants and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the growing factor emotional bettors tend to put on San Francisco’s strength factors between a Diamondbacks team going up against a possibly strong Giants team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Arizona vs San Francisco picks, computer picks Diamondbacks vs Giants, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Diamondbacks Betting Trends
The Diamondbacks enter with a slightly above-average ATS record of 15–13, demonstrating modest success covering the spread.
Giants Betting Trends
The Giants have a 24–21 ATS record overall this season and have gone 29–27 in home games.
Diamondbacks vs. Giants Matchup Trends
The betting market positions San Francisco as a clear favorite (around –196), with Arizona at approximately +162 on the moneyline, and a total set at 8 runs, suggesting a close, pitcher-driven contest where one swing or bullpen move could determine both outcome and cover.
Arizona vs. San Francisco Game Info
What time does Arizona vs San Francisco start on September 08, 2025?
Arizona vs San Francisco starts on September 08, 2025 at 9:45 PM EST.
Where is Arizona vs San Francisco being played?
Venue: Oracle Park.
What are the opening odds for Arizona vs San Francisco?
Spread: San Francisco -1.5
Moneyline: Arizona +155, San Francisco -187
Over/Under: 7.5
What are the records for Arizona vs San Francisco?
Arizona: (72-72) | San Francisco: (72-71)
What is the AI best bet for Arizona vs San Francisco?
Remi's searched hard and found the best prop for this matchup: C. Seymour under 3.5 Pitcher Strikeouts.. Prices move—always shop for the best number.
What are Arizona vs San Francisco trending bets?
The betting market positions San Francisco as a clear favorite (around –196), with Arizona at approximately +162 on the moneyline, and a total set at 8 runs, suggesting a close, pitcher-driven contest where one swing or bullpen move could determine both outcome and cover.
What are Arizona trending bets?
ARI trend: The Diamondbacks enter with a slightly above-average ATS record of 15–13, demonstrating modest success covering the spread.
What are San Francisco trending bets?
SF trend: The Giants have a 24–21 ATS record overall this season and have gone 29–27 in home games.
Where can I find AI Picks for Arizona vs San Francisco?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Arizona vs. San Francisco Odds
Remi is pouring through mountains of data points on each player. In fact, anytime the Arizona vs San Francisco trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable patterns.
Arizona vs San Francisco Opening Odds
ARI Moneyline:
+155 SF Moneyline: -187
ARI Spread: +1.5
SF Spread: -1.5
Over/Under: 7.5
Arizona vs San Francisco Live Odds
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Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
|
–
–
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+100
-120
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-1.5 (+175)
+1.5 (-215)
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O 7 (-105)
U 7 (-115)
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–
–
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+100
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-1.5 (+172)
+1.5 (-210)
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O 7.5 (-110)
U 7.5 (-110)
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10/2/25 8:08PM
Red Sox
Yankees
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–
–
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+136
-162
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+1.5 (-160)
-1.5 (+130)
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O 7.5 (-120)
U 7.5 (-102)
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Oct 4, 2025 2:30PM EDT
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Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
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–
–
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+110
-130
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pk
pk
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Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+108
-126
|
pk
pk
|
O 7 (-135)
U 7 (+115)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Arizona Diamondbacks vs. San Francisco Giants on September 08, 2025 at Oracle Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |