Padres vs. Rockies
Prediction, Odds & Props
Sep 06 | MLB AI Picks
Updated: 2025-09-04T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres visit Coors Field to face the Colorado Rockies in a late-season National League West clash, with Michael King on the mound for San Diego and a Rockies arm—likely Tanner Gordon—set to counter. The action promises a tightly contested duel under Coors’ hitter-friendly skies, where a single big inning could swing the contest.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 06, 2025
Start Time: 8:10 PM EST
Venue: Coors Field
Rockies Record: (40-101)
Padres Record: (76-65)
OPENING ODDS
SD Moneyline: LOADING
COL Moneyline: LOADING
SD Spread: LOADING
COL Spread: LOADING
Over/Under: LOADING
SD
Betting Trends
- San Diego has gone 45–42 against the run line this season, reflecting a modest edge in covering spreads.
COL
Betting Trends
- Colorado struggles on the run line, with a mark of just 42.1%, one of the lowest in MLB.
MATCHUP TRENDS
- Oddsmakers favor the Padres at –1.5 runs, and the over/under is set at 8.5 runs, signaling an expectation for a disciplined, pitcher-involved contest. A single crooked inning could easily decide both the winner and the cover here.
SD vs. COL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: H. Goodman over 1.5 Hits+Runs+RBI.
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San Diego vs Colorado Prediction & Odds:
Free MLB Betting Insights for 9/6/25
Their plan against Gordon or Brown will be to work deep counts, force them to show all their pitches, and wait for the inevitable mistake in the middle of the plate that they can punish, while also taking advantage of Coors’ spacious outfield to stretch singles into doubles. The Rockies, meanwhile, will rely on their young core to provide offensive spark, with players like Ezequiel Tovar and Nolan Jones needing to generate runs by stringing together contact and letting the thin air carry the ball. Their best chance will be to jump on King early before he can settle into rhythm, as San Diego’s bullpen has been inconsistent at times, though certainly stronger than Colorado’s. Defensively, the Padres have the edge, as their infield execution and outfield positioning have been sharper all year compared to Colorado’s often error-prone defense, which has been a big reason why the Rockies sit near the bottom of the league in run prevention. The betting markets reflect the disparity between the clubs: San Diego sits above .500 against the run line, while Colorado owns one of the worst ATS marks in baseball, covering just 42.1% of games, which underscores their inability to keep contests close even when they manage to score runs. With an over/under around 8.5, oddsmakers expect a moderate-scoring game by Coors standards, suggesting faith in King to limit damage and the Padres to control pace, but still allowing room for a big inning on either side to decide things. Ultimately, this game boils down to whether Colorado’s young pitchers can rise to the challenge of facing San Diego’s playoff-caliber lineup in one of the league’s most unforgiving parks, or whether the Padres’ experience, discipline, and superior roster will once again overwhelm a Rockies team that has struggled to string together competitive efforts throughout the season.
Final. pic.twitter.com/gwfiTQ64ni
— San Diego Padres (@Padres) September 6, 2025
San Diego Padres MLB Preview
For the Padres, Saturday’s September 6 game at Coors Field is the type of matchup that can define the consistency of their playoff push, because while San Diego has already taken five of six against the Rockies this season, dropping games to a 100-loss team in September is the sort of slip that can undo weeks of progress in the Wild Card race. The ball goes to Michael King, who has become a stabilizing presence since returning from injury, working with a mix of a firm fastball, a tight slider, and a changeup he trusts to lefties, and his experience makes him uniquely equipped to handle the unique challenge of pitching in Denver’s thin air, where breaking pitches lose bite and even routine fly balls can drift into the seats. King’s mission is to stay aggressive in the zone, avoid falling behind, and trust his defense behind him, because pitching passively in this ballpark is a recipe for trouble. Offensively, the Padres carry a balanced and dangerous lineup, with Manny Machado providing the veteran power, Fernando Tatís Jr. sparking the top with athleticism and flair, and Xander Bogaerts offering a disciplined approach that can extend innings and capitalize on mistakes from young Colorado arms. Depth contributions from hitters like Ha-Seong Kim and Jake Cronenworth further stretch the lineup, giving San Diego the ability to produce runs throughout the order rather than relying solely on their stars.
Their approach against Tanner Gordon or McCade Brown, whichever young arm Colorado sends out, will be to grind at-bats, foul off tough pitches, and force the starter into hitter’s counts, because at Coors, the difference between a strike at the knees and a mistake in the middle is often the difference between a quiet inning and a four-run frame. San Diego’s defense, particularly in the infield, has been reliable and must be sharp in turning double plays to minimize traffic, while the outfielders will need to adjust positioning to handle the wide gaps at Coors, where singles can turn into doubles in a blink. The bullpen has been inconsistent, which is why King’s ability to go deep matters so much, but when aligned correctly, arms like Robert Suarez and others can still lock down high-leverage outs, and manager Mike Shildt will have to be proactive in using matchups to keep the Rockies from stealing momentum. From a betting perspective, San Diego’s 45–42 ATS record demonstrates their tendency to keep games competitive and often cover spreads, while the Rockies’ bottom-tier ATS mark highlights their inability to stay close even at home, giving the Padres a statistical edge that aligns with the on-field matchup. For San Diego, the formula is straightforward: let King set the tone with command and efficiency, have the offense capitalize on young pitching by building early leads, and avoid defensive lapses that allow Colorado free runs. If they execute that blueprint, the Padres not only should walk away with another win in Denver but also strengthen their reputation as a team that takes care of business against inferior opponents, an essential trait for any club looking to play deep into October.

Credit: USA TODAY/IMAGN
Colorado Rockies MLB Preview
For the Rockies, Saturday’s September 6 contest against the Padres at Coors Field is less about chasing postseason dreams and more about pride, player development, and showing their fans signs of progress in a season that has long since slipped away. Colorado enters the game with a dismal record of 39–101, one of the worst in baseball, but the focus at this stage is on giving younger arms like Tanner Gordon or McCade Brown chances to prove themselves against playoff-caliber opponents. Whoever gets the start will need to embrace the challenge of pitching in Denver’s thin air, where mistakes over the plate are magnified and secondary pitches often lose bite, and their path to success will be to get ahead in counts, keep the ball down, and force San Diego’s hitters to put the ball on the ground rather than in the gaps. Offensively, the Rockies turn to their developing core of position players, with Ezequiel Tovar continuing to emerge as a steady presence in the middle infield and Nolan Jones offering some of the only consistent power in the lineup, while veterans like Ryan McMahon provide stability and leadership for younger teammates. Their best chance to compete is to be aggressive early in counts against Michael King, who has the experience and stuff to dominate if allowed to dictate at-bats, but who can also be vulnerable if hitters jump his fastball before he gets into rhythm.
Colorado will also rely on the unique dimensions of Coors Field to generate offense, using the spacious outfield to stretch singles into doubles and testing San Diego’s defense with aggressive baserunning, a strategy that has kept them competitive in occasional spurts despite an overall lack of depth. Defensively, the Rockies must tighten up, as errors and misplays have plagued them all year and contributed heavily to their inability to cover the run line, which they’ve done in only about 42% of games, one of the lowest marks in baseball. Manager Bud Black will look for clean execution from his infield, crisp outfield routes, and smart relay throws to prevent San Diego’s opportunistic lineup from turning traffic into big innings. The bullpen, thin and overworked, remains a liability, so the Rockies’ best path to an upset involves their starter giving them at least five steady innings, followed by selective use of relievers in favorable matchups to keep the game within reach. From a betting standpoint, Colorado’s poor run-line record underscores their tendency to fall apart late, but they can still cover if their offense creates early momentum and their young pitchers surprise with poise. Ultimately, this game is about showcasing effort and development for the Rockies: giving their fans reason to believe in the future, leaning on their young stars to make plays, and proving they can compete with a San Diego team chasing October. If the bats spark and the defense plays clean, Colorado has the chance to disrupt the Padres’ playoff push, and for a team building toward tomorrow, stealing wins in games like this is how they measure progress in an otherwise lost season.
ROX WIN! pic.twitter.com/ZQZmpkQtOA
— Colorado Rockies (@Rockies) September 6, 2025
San Diego vs. Colorado Prop Picks (AI)
San Diego vs. Colorado Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every facet between the Padres and Rockies and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most watching on the linear correlation of factor human bettors often put on San Diego’s strength factors between a Padres team going up against a possibly unhealthy Rockies team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Colorado picks, computer picks Padres vs Rockies, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
San Diego has gone 45–42 against the run line this season, reflecting a modest edge in covering spreads.
Rockies Betting Trends
Colorado struggles on the run line, with a mark of just 42.1%, one of the lowest in MLB.
Padres vs. Rockies Matchup Trends
Oddsmakers favor the Padres at –1.5 runs, and the over/under is set at 8.5 runs, signaling an expectation for a disciplined, pitcher-involved contest. A single crooked inning could easily decide both the winner and the cover here.
San Diego vs. Colorado Game Info
What time does San Diego vs Colorado start on September 06, 2025?
San Diego vs Colorado starts on September 06, 2025 at 8:10 PM EST.
Where is San Diego vs Colorado being played?
Venue: Coors Field.
What are the opening odds for San Diego vs Colorado?
Spread: Colorado LOADING
Moneyline: San Diego LOADING, Colorado LOADING
Over/Under: LOADING
What are the records for San Diego vs Colorado?
San Diego: (76-65) | Colorado: (40-101)
What is the AI best bet for San Diego vs Colorado?
Remi's searched hard and found the best prop for this matchup: H. Goodman over 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are San Diego vs Colorado trending bets?
Oddsmakers favor the Padres at –1.5 runs, and the over/under is set at 8.5 runs, signaling an expectation for a disciplined, pitcher-involved contest. A single crooked inning could easily decide both the winner and the cover here.
What are San Diego trending bets?
SD trend: San Diego has gone 45–42 against the run line this season, reflecting a modest edge in covering spreads.
What are Colorado trending bets?
COL trend: Colorado struggles on the run line, with a mark of just 42.1%, one of the lowest in MLB.
Where can I find AI Picks for San Diego vs Colorado?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Colorado Odds
Remi is pouring through tons of data points on each player. In fact, anytime the San Diego vs Colorado trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.
San Diego vs Colorado Opening Odds
SD Moneyline:
LOADING COL Moneyline: LOADING
SD Spread: LOADING
COL Spread: LOADING
Over/Under: LOADING
San Diego vs Colorado Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
|
–
–
|
+100
-120
|
-1.5 (+175)
+1.5 (-215)
|
O 7 (-105)
U 7 (-115)
|
|
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
|
–
–
|
+100
-118
|
-1.5 (+172)
+1.5 (-210)
|
O 7.5 (-110)
U 7.5 (-110)
|
|
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
|
–
–
|
+136
-162
|
+1.5 (-160)
-1.5 (+130)
|
O 7.5 (-120)
U 7.5 (-102)
|
|
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
|
–
–
|
+110
-130
|
pk
pk
|
|
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Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+108
-126
|
pk
pk
|
O 7 (-135)
U 7 (+115)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Colorado Rockies on September 06, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |