Sox vs. Tigers
Prediction, Odds & Props
Sep 05 | MLB AI Picks
Updated: 2025-09-03T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Tigers open a three-game set with the White Sox at Comerica Park on Friday, September 5, 2025, first pitch 6:40 p.m. ET, with Jack Flaherty lined up against Chicago rookie right-hander Shane Smith. Detroit enters atop the AL Central and heavy home favorites; Chicago arrives on a small uptick and looks to extend recent momentum against a club that has cooled of late.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 05, 2025
Start Time: 6:40 PM EST
Venue: Comerica Park
Tigers Record: (81-60)
Sox Record: (53-88)
OPENING ODDS
CHW Moneyline: +163
DET Moneyline: -197
CHW Spread: +1.5
DET Spread: -1.5
Over/Under: 8.5
CHW
Betting Trends
- Chicago is 7–3 against the run line in its last 10 road games.
DET
Betting Trends
- Detroit is 3–7 against the run line in its last 10 games.
MATCHUP TRENDS
- As a favorite at home, Detroit is 26–21 ATS this season; meanwhile, the Tigers’ season-long run-line cover rate sits just under 50% and they lead the season series 7–3 straight-up — ingredients that can compress margins even when the moneyline leans Detroit.
CHW vs. DET
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: C. Montgomery over 0.5 Total Bases.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
310-227
NET UNITS
(INCL VIG)
+390.9
NET PROFIT
(INCL VIG)
$100/UNIT
$39,086
VS. SPREAD
1564-1335
NET UNITS
(INCL VIG)
+387.3
NET PROFIT
(INCL VIG)
$100/UNIT
$38,728
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Chicago White vs Detroit Prediction & Odds:
Free MLB Betting Insights for 9/5/25
Offensively, the White Sox have been inconsistent all year but have recently shown flashes, with Colson Montgomery’s power spike and Andrew Benintendi’s knack for quality at-bats providing enough life to steal innings if Flaherty falls behind in counts; their challenge will be converting scoring chances, something that has often eluded them, but which has aligned during their better road stretches that have produced covers even against stronger opponents. The Tigers’ lineup, while not overwhelming, plays well at Comerica with its big gaps, relying on gap-to-gap hitting and intelligent baserunning to extend innings, and Greene’s ability to change a game with one swing or a clutch extra-base hit makes him the centerpiece of the order, supported by role players who have provided timely contact throughout the season. From a betting lens, Detroit is the moneyline favorite by virtue of record and venue, but their sub-50% ATS rate and 3–7 ATS mark in their last ten highlight their difficulty in covering spreads, while Chicago’s improved ATS road form makes the run line particularly live, especially in a divisional game where familiarity compresses margins; Detroit also holds a 7–3 straight-up lead in the season series, showing their ability to consistently win, but margin has often been slim. The likely path to a Tigers victory is Flaherty finding strike one early, the lineup converting runners-in-scoring-position chances before the bullpen takes over, and the defense erasing Chicago’s attempts to create chaos, while the White Sox formula relies on Smith bridging six innings with limited damage, the offense getting one or two timely extra-base hits, and the bullpen hanging on in a low-scoring, close game. Ultimately, Detroit’s depth and home pedigree make them the safer play, but the White Sox’s recent ATS form and Smith’s poise create the possibility of a cover or upset, making this divisional opener less predictable than the standings would indicate.
tWINning pic.twitter.com/D5gOFXNQwt
— Chicago White Sox (@whitesox) September 5, 2025
Chicago White Sox MLB Preview
For the Chicago White Sox, this trip to Comerica Park to face the Tigers is another chance to test a young roster against a playoff-caliber team while also riding the modest wave of momentum they have built in recent weeks, going 7–3 ATS on the road and showing that even in a lost season there are signs of progress. The spotlight falls on rookie right-hander Shane Smith, who has quietly emerged as one of the team’s most reliable arms with a 4–7 record and a 3.81 ERA, a mark that belies his composure and ability to give his team competitive innings against some of the league’s better lineups; Smith has showcased his talent in outings like seven scoreless frames against Kansas City and a composed start versus the Yankees, where his mix of a firm fastball and sharp breaking ball induced both weak contact and strikeouts. His success will hinge on establishing first-pitch strikes and keeping Detroit’s left-handed bats, particularly Riley Greene, off balance with pitches on the edges and below the zone, as walks and elevated fastballs can quickly unravel in Comerica’s big dimensions where gap power turns into doubles and triples. Offensively, the White Sox remain streaky, but Colson Montgomery’s emergence as a legitimate power threat and Andrew Benintendi’s steady approach at the plate provide a foundation that can produce runs when they are disciplined, and the formula for them is to extend counts against Jack Flaherty, force him into hitter’s counts, and capitalize on mistakes with timely extra-base hits.
The supporting cast has been inconsistent, but with a bit of timely production from role players, the Sox can turn small opportunities into runs, especially if they execute situational hitting and avoid leaving traffic stranded, which has often been their undoing this season. Defensively, Chicago’s inconsistency has cost them dearly in 2025, with unforced errors extending innings, but when the fielders execute behind Smith, the team has looked far more competitive, particularly in one-run games, where their sharper execution on the road has shown up in their ATS record. The bullpen remains volatile, with injuries and role shuffling affecting reliability, so Smith’s ability to get deep into the game is vital to prevent exposing the weakest parts of their relief corps, and if he can hand off with a lead or even a tie, the White Sox at least give themselves a fighting chance to close out a low-scoring contest. From a betting angle, the White Sox have actually outperformed expectations away from home recently, and in divisional games where familiarity compresses gaps, they have proven capable of hanging around even when the odds are against them. To engineer an upset, the White Sox need Smith to hold Detroit’s bats quiet through six innings, the lineup to strike early against Flaherty before the bullpen enters its comfort zone, and the defense to play clean, avoiding the unforced errors that turn competitive outings into lopsided defeats. Even if the win doesn’t materialize, this formula gives Chicago a legitimate chance to cover again on the road and continue a trend that has provided small but meaningful silver linings in an otherwise difficult season.

Credit: USA TODAY/IMAGN
Detroit Tigers MLB Preview
For the Detroit Tigers, opening this divisional set against the White Sox at Comerica Park is about reasserting their dominance after a recent 3–7 skid that has tempered but not derailed their stronghold on the AL Central, as they enter at 81–60 overall with a 45–27 mark at home, numbers that confirm they have been one of the most reliable home-field clubs in the league. The starting assignment goes to Jack Flaherty, who at 7–13 with a 4.74 ERA has been inconsistent, alternating sharp outings with struggles where command lapses early and pitch counts escalate, and his ability to locate first-pitch strikes and sequence his slider effectively will dictate whether Detroit starts the series on solid footing or leaves an opening for Chicago’s underdog push. The Tigers’ offense has been steady, built around Riley Greene’s star turn as the anchor of the lineup with over 30 home runs and triple-digit RBI pace, while Dillon Dingler has emerged as a timely contributor, and the supporting cast has embraced Comerica’s spacious gaps by focusing on line drives and situational hitting rather than leaning solely on power. Their baserunning has been intelligent, turning singles into doubles and applying pressure on defenses, which aligns with manager A.J. Hinch’s emphasis on manufacturing runs in a ballpark that rewards extra hustle as much as it does raw slug. Defensively, the Tigers have been sharper than in recent years, converting balls in play into outs with efficiency, which allows pitchers like Flaherty to pitch more to contact without fear of extended innings, though avoiding walks remains the key to keeping games under control.
The bullpen has developed into a genuine strength, with roles now defined and multiple high-leverage arms capable of handling both right- and left-handed matchups, giving Detroit confidence that if they secure a lead by the seventh inning, they can protect it with consistency. From a betting standpoint, Detroit’s straight-up record makes them a deserved favorite, but their ATS profile is less convincing, with a sub-50% season-long cover rate and just 3–7 ATS in their last 10, which suggests that while they win often, margins tend to be slimmer than expected. Still, Detroit has handled Chicago well in 2025, leading the season series 7–3, a reflection of their deeper roster, steadier pitching, and ability to capitalize on White Sox mistakes, and that divisional familiarity gives them a blueprint for handling this matchup. For the Tigers, the path to victory involves Flaherty setting the tone with first-inning command, the lineup cashing in runners in scoring position early to build cushion, and the bullpen maintaining control late, while the defense ensures the White Sox cannot extend innings with unearned chances. If Detroit executes to its usual home standard, this game provides a chance to snap recent ATS frustration, reestablish rhythm ahead of a crucial September stretch, and reinforce why Comerica Park has been a fortress for them all season.
‘25 Tigs 🐅 pic.twitter.com/IDk80ZBPMQ
— Detroit Tigers (@tigers) September 4, 2025
Chicago White vs. Detroit Prop Picks (AI)
Chicago White vs. Detroit Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Sox and Tigers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Remi has been most focused on the growing weight human bettors tend to put on coaching factors between a Sox team going up against a possibly healthy Tigers team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Chicago White vs Detroit picks, computer picks Sox vs Tigers, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
![]() |
|
MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
![]() |
|
MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
![]() |
|
MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
![]() |
|
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
![]() |
|
MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
![]() |
|
MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Sox Betting Trends
Chicago is 7–3 against the run line in its last 10 road games.
Tigers Betting Trends
Detroit is 3–7 against the run line in its last 10 games.
Sox vs. Tigers Matchup Trends
As a favorite at home, Detroit is 26–21 ATS this season; meanwhile, the Tigers’ season-long run-line cover rate sits just under 50% and they lead the season series 7–3 straight-up — ingredients that can compress margins even when the moneyline leans Detroit.
Chicago White vs. Detroit Game Info
What time does Chicago White vs Detroit start on September 05, 2025?
Chicago White vs Detroit starts on September 05, 2025 at 6:40 PM EST.
Where is Chicago White vs Detroit being played?
Venue: Comerica Park.
What are the opening odds for Chicago White vs Detroit?
Spread: Detroit -1.5
Moneyline: Chicago White +163, Detroit -197
Over/Under: 8.5
What are the records for Chicago White vs Detroit?
Chicago White: (53-88) | Detroit: (81-60)
What is the AI best bet for Chicago White vs Detroit?
Remi's searched hard and found the best prop for this matchup: C. Montgomery over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Chicago White vs Detroit trending bets?
As a favorite at home, Detroit is 26–21 ATS this season; meanwhile, the Tigers’ season-long run-line cover rate sits just under 50% and they lead the season series 7–3 straight-up — ingredients that can compress margins even when the moneyline leans Detroit.
What are Chicago White trending bets?
CHW trend: Chicago is 7–3 against the run line in its last 10 road games.
What are Detroit trending bets?
DET trend: Detroit is 3–7 against the run line in its last 10 games.
Where can I find AI Picks for Chicago White vs Detroit?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White vs. Detroit Odds
AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Chicago White vs Detroit trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.
Chicago White vs Detroit Opening Odds
CHW Moneyline:
+163 DET Moneyline: -197
CHW Spread: +1.5
DET Spread: -1.5
Over/Under: 8.5
Chicago White vs Detroit Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
|
–
–
|
+100
-120
|
-1.5 (+175)
+1.5 (-215)
|
O 7 (-105)
U 7 (-115)
|
|
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
|
–
–
|
+100
-118
|
-1.5 (+172)
+1.5 (-210)
|
O 7.5 (-110)
U 7.5 (-110)
|
|
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
|
–
–
|
+136
-162
|
+1.5 (-160)
-1.5 (+130)
|
O 7.5 (-120)
U 7.5 (-102)
|
|
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
|
–
–
|
+110
-130
|
pk
pk
|
|
|
Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+108
-126
|
pk
pk
|
O 7 (-135)
U 7 (+115)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago White Sox vs. Detroit Tigers on September 05, 2025 at Comerica Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |