vs. Cardinals
Prediction, Odds & Props
Sep 01 | MLB AI Picks
Updated: 2025-08-30T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Athletics, sitting at approximately 32–48, enter this matchup as rebuilding underdogs facing the Cardinals, who hold a near .500 record around 64–67 and remain loosely in the hunt for a postseason spot. Both teams are navigating contrasting seasons—Oakland is developing talent and building for the future, while St. Louis still clings to relevance in a competitive NL Central, making this matchup a test of progress versus perseverance.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 01, 2025
Start Time: 2:15 PM EST
Venue: Busch Stadium
Cardinals Record: (68-70)
Record: (63-75)
OPENING ODDS
ATH Moneyline: +118
STL Moneyline: -141
ATH Spread: +1.5
STL Spread: -1.5
Over/Under: 8
ATH
Betting Trends
- No explicit current ATS data found, but they’ve generally struggled to cover and are widely considered underdogs.
STL
Betting Trends
- Also lack precise ATS figures, but with their stronger performance and home environment, they’re favored in most markets.
MATCHUP TRENDS
- Historically, when these teams met, totals often ran under 9 runs, indicating pitching and defense—rather than offensive explosiveness—were expected to dictate outcomes. 
ATH vs. STL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: P. Pages over 3.5 Fantasy Score.
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Athletics vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 9/1/25
Oakland, meanwhile, continues to piece together an offense that relies heavily on streaky contributors such as Brent Rooker, with little depth behind him to support sustained scoring, while their pitching staff has been among the weakest in the league, plagued by short outings from starters and overexposed relievers who have struggled to hold leads. Oddsmakers have reflected this gap, listing the Cardinals as solid favorites, with Oakland carrying a +1.5 run line as the only realistic way for bettors to find value, while the total for the game is projected at around nine runs, suggesting expectations of a modestly scoring contest where St. Louis’ ability to capitalize on opportunities should determine the outcome. For the Athletics, the path to an upset would involve an uncharacteristically strong start from their rotation, opportunistic offense that takes advantage of any mistakes from St. Louis pitchers, and flawless execution on defense, all of which have been rare occurrences during a frustrating 2025 campaign. The Cardinals, on the other hand, simply need to play to their strengths—drive up pitch counts against inexperienced A’s pitchers, lean on their veteran bats to push runs across early, and let their bullpen protect whatever lead they can build. While the stakes are minimal for Oakland, they remain significant for St. Louis, and that dynamic creates a matchup where one team is playing for its future and the other for its present, a contrast that should result in the Cardinals playing with urgency and the A’s with nothing to lose. Ultimately, this game represents an opportunity for St. Louis to stabilize its season and keep faint playoff dreams alive, while Oakland will be content to play spoiler and evaluate whether its young talent can rise to the challenge of facing a desperate contender.
— Athletics (@Athletics) August 31, 2025
Athletics MLB Preview
The Oakland Athletics enter their September 1, 2025 matchup against the St. Louis Cardinals at Busch Stadium with a record of roughly 32–48, a figure that reinforces the reality of a franchise still deep in rebuild mode and struggling to establish traction at the major league level. For Oakland, this season has been less about wins and losses and more about evaluating prospects, identifying pieces of a future core, and giving younger players extended opportunities to face big-league competition. Brent Rooker has been one of the few bright spots offensively, occasionally providing power that sparks an otherwise inconsistent lineup, but the lack of depth and steady contributors throughout the batting order has left the A’s among the lowest-scoring teams in baseball. Their approach has leaned heavily on situational hitting and small ball when possible, yet they too often come up empty in key moments, stranding runners and failing to produce in clutch spots. On the mound, the rotation has been a revolving door, with too few pitchers able to provide quality innings or pitch deep into games, which has in turn left the bullpen overexposed and vulnerable.
That relief corps has been one of the league’s weakest, frequently unable to hold leads even in games where the offense manages to stake them ahead, contributing to an inflated run differential that underscores the team’s struggles. Defensively, the A’s have shown some promise from their younger infielders, but lapses and miscues have also been common, adding further hurdles in close contests. As +1.5 run line underdogs, they enter this game with little market confidence, but the spread suggests they can sometimes hang around and keep things close if they get an unexpected strong outing from a starter or if their bats manage to find holes against opposing pitching. Against the Cardinals, a team hovering around .500 and still alive in the playoff race, the A’s will need to play nearly perfect baseball to have a shot, which means early run production from Rooker and company, defensive sharpness to avoid gifting extra opportunities, and bullpen arms rising above their season averages to prevent a late collapse. While the postseason is long out of sight for Oakland, games like this are still valuable—both as a chance for younger players to test themselves against a club with playoff aspirations and as an opportunity for the team to embrace the spoiler role, something that can provide at least a small sense of satisfaction in a season otherwise defined by growing pains.

Credit: USA TODAY/IMAGN
St. Louis Cardinals MLB Preview
The St. Louis Cardinals enter their September 1, 2025 matchup against the Oakland Athletics at Busch Stadium with a record of about 64–67, a mark that reflects a season of mediocrity but one that still leaves them on the fringes of the National League Wild Card race. While the Cardinals haven’t lived up to the lofty expectations that come with their tradition-rich history, they remain competitive enough to keep their postseason hopes alive, and games like this against a struggling opponent take on outsized importance as they simply cannot afford to drop contests to rebuilding clubs like Oakland. Offensively, St. Louis still leans on its veteran stars, with Paul Goldschmidt and Nolan Arenado continuing to provide the kind of steady run production that keeps the lineup dangerous, while contributions from younger players have helped balance out stretches where the offense has gone quiet. They average around 4.4 runs per game while allowing 4.6, numbers that illustrate why their run differential is close to neutral and why they’ve hovered just below .500 all season, but at home they’ve typically found more consistency, using Busch Stadium’s dimensions and supportive crowds to grind out wins.
On the mound, the rotation has been serviceable if unspectacular, giving them chances to compete most nights, while the bullpen has shown improvement as roles have become more defined, allowing manager Oliver Marmol to manage late innings with greater confidence than earlier in the season. Defensively, the Cardinals have remained solid, rarely giving away extra outs, and their experience in close games has often allowed them to find ways to win when execution is at a premium. Oddsmakers have given them the edge in this matchup, with a –1.5 run line at + odds reflecting expectations that they should not only win but have the ability to do so comfortably against an Athletics club that struggles to score and consistently hold leads. For the Cardinals, the keys to success in this game are straightforward: apply early pressure on Oakland’s inexperienced pitching staff, avoid defensive lapses that give the A’s free opportunities, and lean on their veteran hitters to provide timely production that puts the contest out of reach by the middle innings. With their season hanging in the balance, this is precisely the type of game St. Louis must win if it wants to remain in the postseason conversation, and while the Athletics may embrace the spoiler role, the Cardinals know they have the depth, experience, and urgency to take care of business at home. For St. Louis, it’s less about style points and more about results, and with the standings tightening by the day, this matchup provides an opportunity to steady their season and keep the chase alive into September.
First big league home run for Jimmy Crooks! 💥 pic.twitter.com/sG0xaKiGwY
— St. Louis Cardinals (@Cardinals) August 31, 2025
Athletics vs. St. Louis Prop Picks (AI)
Athletics vs. St. Louis Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every past game between the and Cardinals and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.
The Algorithm has been most watching on the growing factor human bettors regularly put on player performance factors between a team going up against a possibly deflated Cardinals team. In reality, the true game analytics might reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Athletics vs St. Louis picks, computer picks vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Betting Trends
No explicit current ATS data found, but they’ve generally struggled to cover and are widely considered underdogs.
Cardinals Betting Trends
Also lack precise ATS figures, but with their stronger performance and home environment, they’re favored in most markets.
vs. Cardinals Matchup Trends
Historically, when these teams met, totals often ran under 9 runs, indicating pitching and defense—rather than offensive explosiveness—were expected to dictate outcomes. 
Athletics vs. St. Louis Game Info
What time does Athletics vs St. Louis start on September 01, 2025?
Athletics vs St. Louis starts on September 01, 2025 at 2:15 PM EST.
Where is Athletics vs St. Louis being played?
Venue: Busch Stadium.
What are the opening odds for Athletics vs St. Louis?
Spread: St. Louis -1.5
Moneyline: Athletics +118, St. Louis -141
Over/Under: 8
What are the records for Athletics vs St. Louis?
Athletics: (63-75) | St. Louis: (68-70)
What is the AI best bet for Athletics vs St. Louis?
Remi's searched hard and found the best prop for this matchup: P. Pages over 3.5 Fantasy Score.. Prices move—always shop for the best number.
What are Athletics vs St. Louis trending bets?
Historically, when these teams met, totals often ran under 9 runs, indicating pitching and defense—rather than offensive explosiveness—were expected to dictate outcomes. 
What are Athletics trending bets?
ATH trend: No explicit current ATS data found, but they’ve generally struggled to cover and are widely considered underdogs.
What are St. Louis trending bets?
STL trend: Also lack precise ATS figures, but with their stronger performance and home environment, they’re favored in most markets.
Where can I find AI Picks for Athletics vs St. Louis?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Athletics vs. St. Louis Odds
AI algorithm Remi is pouring through tons of data on each line. In fact, anytime the Athletics vs St. Louis trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable patterns.
Athletics vs St. Louis Opening Odds
ATH Moneyline:
+118 STL Moneyline: -141
ATH Spread: +1.5
STL Spread: -1.5
Over/Under: 8
Athletics vs St. Louis Live Odds
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Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
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–
–
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+100
-120
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-1.5 (+175)
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O 7 (-105)
U 7 (-115)
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10/2/25 5:08PM
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–
–
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+100
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-1.5 (+172)
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O 7.5 (-110)
U 7.5 (-110)
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Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
|
–
–
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+136
-162
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+1.5 (-160)
-1.5 (+130)
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O 7.5 (-120)
U 7.5 (-102)
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Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
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10/4/25 2:30PM
Dodgers
Phillies
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–
–
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+110
-130
|
pk
pk
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Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
|
–
–
|
+108
-126
|
pk
pk
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O 7 (-135)
U 7 (+115)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Athletics vs. St. Louis Cardinals on September 01, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |