Cubs vs Giants Prediction — AI Finds CAN'T MISS MLB Lines & Props (Aug 28)
Updated: 2025-08-26T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Chicago Cubs (76–56) close out their west coast road swing tonight at Oracle Park against the struggling San Francisco Giants (64–68), in a matchup that carries playoff significance for Chicago as they brace to defend their #1 NL Wild Card spot. Chicago enters the game as a strong favorite at around –160, with the total runs line set near 8.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 28, 2025
Start Time: 3:45 PM EST
Venue: Oracle Park
Giants Record: (65-68)
Cubs Record: (76-57)
OPENING ODDS
CHC Moneyline: -102
SF Moneyline: -118
CHC Spread: -1.5
SF Spread: +1.5
Over/Under: 7
CHC
Betting Trends
- The Cubs have gone 28–29 against the run line this season, illustrating middling performance in spread-based betting scenarios.
SF
Betting Trends
- While an exact figure wasn’t available, the Giants have lacked consistency at home—posting an 8–22 record over their last 30 home games—suggesting they’ve struggled to cover at Oracle Park recently.
MATCHUP TRENDS
- Chicago’s games frequently attract under bettors, bolstered by their disciplined offense and the pitcher-friendly nature of Oracle Park—the total line of 8 supports a likely lower-scoring affair.
CHC vs. SF
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: L. Matos over 0.5 Hits+Runs+RBI.
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Chicago vs San Francisco Prediction & Odds:
Free MLB Betting Insights for 8/28/25
The Giants, in contrast, enter the contest having struggled mightily at home with an 8–22 record across their last 30 Oracle Park games, a trend that has erased what was once one of the strongest home-field advantages in baseball, and the inconsistency has come from both the mound and the plate. Rafael Devers, acquired midseason in a headline-grabbing move, has added a power element that the team sorely needed, and younger players like Luis Matos and Casey Schmitt have shown flashes of promise, but the lineup as a whole has been inconsistent, often failing to string together hits or execute in run-scoring situations. Their pitching staff has had moments of effectiveness but lacks the depth to match contenders like the Cubs, with starters struggling to work deep into games and a bullpen that has been asked to shoulder too much responsibility, leading to late-inning breakdowns. From a betting perspective, Chicago has been favored at around –160 for this matchup, with their performance against the spread hovering near .500 but still reflecting a greater reliability than San Francisco, whose volatility has made them a riskier proposition for bettors. The total run line of 8 also points toward the pitcher-friendly environment of Oracle Park, suggesting a lower-scoring contest unless one side’s bullpen falters significantly. For the Cubs, this is about continuing to build momentum and refining the playoff habits that will carry them into October, while for the Giants it is about pride, development, and the chance to disrupt a contender’s rhythm even as their own postseason hopes fade. In essence, this game is a microcosm of the two clubs’ seasons: one team sharpening its playoff edge, the other searching for stability and signs of hope in an uneven year.
Nooo doubt about this one from Nico! pic.twitter.com/8lh7a08IeM
— Chicago Cubs (@Cubs) August 28, 2025
Chicago Cubs MLB Preview
The Chicago Cubs travel to Oracle Park on August 28, 2025 to face the San Francisco Giants as a team defined by resilience, balance, and the determination to extend their 76–56 record into postseason success, and this contest reflects both their current momentum and their identity as one of the National League’s most consistent performers in 2025. Offensively, the Cubs have showcased a lineup that combines patience with punch, beginning with Seiya Suzuki’s steady power and contact skills anchoring the order, Michael Busch providing pop from the left side, Kyle Tucker’s midseason arrival bolstering both power and defensive range, and Pete Crow-Armstrong adding speed and athleticism that changes games both on the basepaths and in the outfield. Together, this core has given Chicago the ability to produce runs in a variety of ways, whether through long balls, situational hitting, or pressure created by aggressiveness on the bases, while veterans like Ian Happ and Nico Hoerner contribute stability, on-base production, and leadership. Their offensive philosophy hinges on working deep counts, forcing opposing pitchers into mistakes, and capitalizing in clutch moments, a formula that has translated into late-inning rallies and has kept them firmly in Wild Card control. On the mound, while the Cubs’ rotation does not boast overwhelming dominance, it has been serviceable enough to consistently hand games to a bullpen that has developed into a reliable unit capable of handling high-leverage innings with poise.
Relievers like Adbert Alzolay and Julian Merryweather have played key roles in bridging the gap from the middle innings to late-game closers, and the staff as a whole has demonstrated the ability to protect narrow leads, a critical factor in a playoff chase. Defensively, the Cubs have also excelled, with Crow-Armstrong’s elite range in the outfield, Tucker’s strong arm, and Hoerner’s infield steadiness contributing to a unit that prevents extra runs and complements their pitching staff’s pitch-to-contact tendencies. From a betting perspective, Chicago has been a modest performer against the spread at 28–29 but has delivered when favored in matchups against struggling teams like San Francisco, and the –160 moneyline reflects oddsmakers’ confidence in their ability to extend their advantage here. The environment at Oracle Park, with its cavernous dimensions and pitcher-friendly tendencies, may temper offensive explosions, but the Cubs’ lineup is versatile enough to grind out runs even when conditions favor the defense, giving them an edge in lower-scoring contests. For manager Craig Counsell, this game is less about a single win and more about reinforcing habits and sharpening execution as his team prepares for October, ensuring that players remain disciplined and consistent in all phases of the game. For the Cubs, the matchup is another checkpoint in their broader journey, a chance to demonstrate why they are among the most formidable postseason contenders in the National League, and to remind rivals that their blend of patience, athleticism, and resilience makes them a dangerous opponent capable of thriving in any environment, even one as challenging as Oracle Park.

Credit: USA TODAY/IMAGN
San Francisco Giants MLB Preview
The San Francisco Giants enter their August 28, 2025 home matchup against the Chicago Cubs carrying a 64–68 record that encapsulates a season defined by inconsistency, home-field struggles, and the ongoing tension between rebuilding and competing, and this game at Oracle Park provides both a chance to test themselves against a playoff contender and to show their fan base that pride and growth remain central even in a difficult campaign. Once a team that relied on Oracle Park as a fortress, the Giants have endured a woeful 8–22 stretch at home over their last 30 games, an alarming trend that has drained momentum and made every contest in front of their supporters feel like an uphill battle. Offensively, the club has attempted to balance the development of young talent with the acquisition of star power, most notably Rafael Devers, whose midseason arrival brought credibility and pop to a lineup that had often struggled to produce runs in bunches. Devers’ bat has provided a veteran anchor, but the reliance on younger players like Luis Matos, Casey Schmitt, and Heliot Ramos has produced uneven results, with flashes of brilliance offset by stretches of inconsistency, a reminder that their best contributions are still ahead of them rather than in the present. At their best, the Giants’ offense can string together hits and create rallies with a mix of contact, opportunistic baserunning, and timely power, but at their worst they disappear entirely, failing to support a pitching staff that has been asked to do far too much.
On the mound, the rotation has had difficulty working deep into games, forcing heavy reliance on a bullpen that has often been tasked with covering too many innings, leading to late-game collapses and fatigue as the season has worn on. While certain relievers have performed admirably in high-leverage spots, the overall lack of stability has left the Giants vulnerable in tight games, a stark contrast to their opponent’s steadier late-inning execution. Defensively, the Giants have benefited from the athleticism of Matos in the outfield and Schmitt in the infield, but lapses in focus have cost them extra outs at critical junctures, magnifying their struggles in close contests. From a betting perspective, their unreliability at Oracle Park has made them a difficult team to back, as their inconsistency has led to volatility against the spread, further reflecting the underlying issues with execution and consistency. Manager Bob Melvin has faced the dual challenge of trying to win now while also providing meaningful development for his younger players, and that balancing act has been evident in the team’s uneven results. For the Giants, this matchup against the Cubs is about more than the standings; it is about testing their youth against one of the National League’s most complete rosters, showing that they can still compete with clubs destined for October, and offering their fans signs of hope that the talent being cultivated now will form the foundation of a more competitive future. A strong performance against Chicago would not only lift morale but also provide validation that even in a tough year, progress is being made, and that with the right blend of veteran leadership and continued development, San Francisco’s path back to contention remains alive.
Quite the night at @OracleParkSF 😁 pic.twitter.com/pUCRYVhGkJ
— SFGiants (@SFGiants) August 28, 2025
Chicago vs. San Francisco Prop Picks (AI)
Chicago vs. San Francisco Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every simulation between the Cubs and Giants and using recursive machine learning and industry leading AI to examine the data to a single cover probability.
Interestingly enough, the data has been most fixated on the linear correlation of emphasis emotional bettors regularly put on coaching factors between a Cubs team going up against a possibly strong Giants team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Chicago vs San Francisco picks, computer picks Cubs vs Giants, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Cubs Betting Trends
The Cubs have gone 28–29 against the run line this season, illustrating middling performance in spread-based betting scenarios.
Giants Betting Trends
While an exact figure wasn’t available, the Giants have lacked consistency at home—posting an 8–22 record over their last 30 home games—suggesting they’ve struggled to cover at Oracle Park recently.
Cubs vs. Giants Matchup Trends
Chicago’s games frequently attract under bettors, bolstered by their disciplined offense and the pitcher-friendly nature of Oracle Park—the total line of 8 supports a likely lower-scoring affair.
Chicago vs. San Francisco Game Info
What time does Chicago vs San Francisco start on August 28, 2025?
Chicago vs San Francisco starts on August 28, 2025 at 3:45 PM EST.
Where is Chicago vs San Francisco being played?
Venue: Oracle Park.
What are the opening odds for Chicago vs San Francisco?
Spread: San Francisco +1.5
Moneyline: Chicago -102, San Francisco -118
Over/Under: 7
What are the records for Chicago vs San Francisco?
Chicago: (76-57) | San Francisco: (65-68)
What is the AI best bet for Chicago vs San Francisco?
Remi's searched hard and found the best prop for this matchup: L. Matos over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are Chicago vs San Francisco trending bets?
Chicago’s games frequently attract under bettors, bolstered by their disciplined offense and the pitcher-friendly nature of Oracle Park—the total line of 8 supports a likely lower-scoring affair.
What are Chicago trending bets?
CHC trend: The Cubs have gone 28–29 against the run line this season, illustrating middling performance in spread-based betting scenarios.
What are San Francisco trending bets?
SF trend: While an exact figure wasn’t available, the Giants have lacked consistency at home—posting an 8–22 record over their last 30 home games—suggesting they’ve struggled to cover at Oracle Park recently.
Where can I find AI Picks for Chicago vs San Francisco?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago vs. San Francisco Odds
AI algorithm Remi is pouring through mountains of data points on each player. In fact, anytime the Chicago vs San Francisco trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.
Chicago vs San Francisco Opening Odds
CHC Moneyline:
-102 SF Moneyline: -118
CHC Spread: -1.5
SF Spread: +1.5
Over/Under: 7
Chicago vs San Francisco Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
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–
–
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-154
+125
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-1.5 (+112)
+1.5 (-142)
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O 7.5 (-102)
U 7.5 (-125)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago Cubs vs. San Francisco Giants on August 28, 2025 at Oracle Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |