Padres vs Mariners Prediction — AI Finds CAN'T MISS MLB Lines & Props (Aug 25)
Updated: 2025-08-23T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres visit T-Mobile Park on August 25, 2025, to take on the Seattle Mariners in a late-season showdown with both teams jockeying for playoff relevance in their respective leagues; the Mariners, slight favorites at home, look to leverage their divisional positioning and rising momentum, while the Padres, underdogs on the road, aim to push into Wild Card contention with disciplined pitching and a lineup capable of erupting offensively.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 25, 2025
Start Time: 9:40 PM EST
Venue: T-Mobile Park
Mariners Record: (70-61)
Padres Record: (74-57)
OPENING ODDS
SD Moneyline: +109
SEA Moneyline: -128
SD Spread: +1.5
SEA Spread: -1.5
Over/Under: 8
SD
Betting Trends
- Entering as underdogs at +109 on the moneyline, the Padres have been a strong value pick this season, posting a solid 27–17 record against the spread.
SEA
Betting Trends
- Favored at –130, the Mariners have been respectable at home as chalk, going 24–20 ATS when installed as favorites.
MATCHUP TRENDS
- Both teams show healthy betting momentum, making this a competitive matchup with potential ATS opportunities on both sides.
SD vs. SEA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: M. Garver over 0.5 Hits+Runs+RBI.
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San Diego vs Seattle Prediction & Odds:
Free MLB Betting Insights for 8/25/25
Betting trends lend slight edge to Seattle at home, but the 8-run total suggests scoring volatility, particularly if both bullpens collapse or aggressive bats catch fire. Strategically, San Diego must coax early runs against Seattle’s rotation, then lean on bullpen depth to hold onto leads, while Seattle needs to generate offense in the early innings and let their bench or bullpen shifts tilt the scoring in later frames. Weather, as expected in August, isn’t a major factor given Globe’s dome-like environment, which tends to suppress dramatic swings and favor pitching precision. With the win-loss records nearly mirroring each other—Padres 74–57, Mariners 68–58—and both eyeing postseason clarity, this one game could tip the balance. If San Diego executes like the reliable underdog they’ve been all year, they could steal a critical road win; but Seattle’s home comfort, power depth, and improved defense present a formidable obstacle. This contest will likely come down to which team better controls the strike zone and executes in tight spots—a true measuring stick game for both clubs.
Final. pic.twitter.com/RVJ7IqRgiK
— San Diego Padres (@Padres) August 24, 2025
San Diego Padres MLB Preview
The San Diego Padres enter their August 25, 2025, matchup against the Seattle Mariners looking to continue building late-season momentum and maintain their position in the National League Wild Card race, armed with one of the more complete rosters in baseball and a reputation for clutch road performances. Currently hovering around the 75-win mark, the Padres have been a reliable force both in terms of wins and covering the spread, boasting a 27–17 ATS road record that underscores their consistency outside Petco Park. The offense is led by the powerful and dynamic duo of Manny Machado and Fernando Tatis Jr., both of whom remain the linchpins of San Diego’s run production, supported by young hitters like Jackson Merrill and veterans such as Jake Cronenworth and Xander Bogaerts, who have been quietly impactful with timely hits and defensive stability. This lineup has improved its OBP in the second half of the season, extending innings and pushing up pitch counts, making them dangerous against even elite pitching. The starting rotation has stabilized after early-season inconsistency, with left-hander J.P. Sears set to take the mound against the Mariners; Sears has quietly impressed with a mid-3.00s ERA and excellent command, particularly against right-handed hitters, which should play well against Seattle’s lineup that features several powerful righty bats. Backing him is a bullpen anchored by Robert Suarez and Josh Hader, forming one of the most effective late-inning duos in the majors, particularly when protecting narrow leads on the road.
The Padres’ defense has been another bright spot, ranking top-five in fielding percentage and excelling in limiting extra-base damage, especially in spacious outfields like Seattle’s T-Mobile Park. In terms of matchups, San Diego has fared well against AL West teams this season, posting a winning record in interleague play and showing the ability to adjust to unfamiliar pitchers quickly—an edge that may matter against Bryce Miller, Seattle’s probable starter. The Padres’ managerial staff has also done an excellent job with situational calls, particularly around pinch-hitting and bullpen matchups, often squeezing out narrow victories with aggressive but calculated decisions. San Diego knows the stakes are rising with each series, and with teams like the Braves, Phillies, and Brewers ahead in the playoff picture, they cannot afford to stumble, especially in winnable matchups like this one. A key for the Padres will be controlling the game tempo early—scoring in the first three innings and pressuring Seattle’s young pitchers to throw under duress. While Seattle presents a difficult challenge at home, the Padres’ blend of power, plate discipline, reliable pitching, and road confidence make them a dangerous opponent capable of flipping momentum at any point. Expect them to come out assertive, likely trying to attack Bryce Miller early in counts while giving J.P. Sears a cushion to pitch confidently from ahead. If they execute in key moments and limit strikeouts against Seattle’s bullpen, the Padres are well positioned to notch another critical late-season win and keep their playoff drive fully alive.

Credit: USA TODAY/IMAGN
Seattle Mariners MLB Preview
The Seattle Mariners enter their August 25, 2025 showdown with the San Diego Padres at T-Mobile Park aiming to stay in the thick of the American League Wild Card hunt, continuing a campaign marked by dominant home performances, elite pitching, and a young but maturing lineup that has gradually come into its own over the summer. Seattle boasts one of the better home records in the AL this year, with a strong 34–22 mark in front of their fans and an ATS home record that’s been equally reliable, especially when their starting pitching is on point. Bryce Miller is expected to take the mound for the Mariners, and while his rookie season had a few early bumps, he’s developed into a poised, high-leverage arm with a fastball that can touch the upper 90s and a secondary arsenal that’s proven effective against righty-heavy lineups like the Padres. Miller’s ability to limit walks and generate weak contact has been crucial for a team that often leans on tight, low-scoring games to earn wins. The Mariners’ bullpen remains one of the best in baseball, with Andrés Muñoz and Matt Brash emerging as shutdown options late in games, giving manager Scott Servais the confidence to shorten games effectively when Seattle leads after six innings. Offensively, the Mariners are led by Julio Rodríguez, who remains the face of the franchise and has heated up post-All-Star break, not only with the bat but also with his legs and glove. He’s supported by the likes of Cal Raleigh, whose power from the catcher position gives Seattle thump in the middle of the order, and Ty France, who offers steady production and smart situational hitting.
While this team still has a tendency to go cold offensively at times—particularly with runners in scoring position—they’ve recently improved their plate discipline, cutting down strikeouts and drawing more walks, a trend they’ll hope continues against a Padres staff that doesn’t give up many freebies. Defensively, Seattle is one of the sharper units in the league, with J.P. Crawford anchoring the infield and Rodríguez covering massive ground in center, limiting the damage on balls in play and supporting their pitching-first philosophy. The Mariners have also done well in interleague play this year, especially against NL West opponents, and their familiarity with facing elite pitching has helped them stay competitive in tight series. This game holds significant implications for Seattle, not only in terms of playoff standings but also in setting the tone for a difficult upcoming stretch that includes matchups with the Astros and Yankees. A win here would reinforce their identity as a postseason-caliber squad that can neutralize power offenses and outlast opponents with precision and grit. To do that, they’ll need Bryce Miller to pitch deep into the game and the lineup to capitalize on early scoring opportunities—particularly if they can get to J.P. Sears before the Padres turn things over to their excellent bullpen. With postseason urgency intensifying, the Mariners will look to defend their home turf with the same discipline and energy that’s defined their season thus far.
Record rewritten. #TridentsUp pic.twitter.com/cxo8uXWSZE
— Seattle Mariners (@Mariners) August 24, 2025
San Diego vs. Seattle Prop Picks (AI)
San Diego vs. Seattle Prediction (AI)

Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every angle between the Padres and Mariners and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Remi has been most focused on the unproportionally assigned emphasis emotional bettors often put on coaching factors between a Padres team going up against a possibly unhealthy Mariners team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Seattle picks, computer picks Padres vs Mariners, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
Entering as underdogs at +109 on the moneyline, the Padres have been a strong value pick this season, posting a solid 27–17 record against the spread.
Mariners Betting Trends
Favored at –130, the Mariners have been respectable at home as chalk, going 24–20 ATS when installed as favorites.
Padres vs. Mariners Matchup Trends
Both teams show healthy betting momentum, making this a competitive matchup with potential ATS opportunities on both sides.
San Diego vs. Seattle Game Info
What time does San Diego vs Seattle start on August 25, 2025?
San Diego vs Seattle starts on August 25, 2025 at 9:40 PM EST.
Where is San Diego vs Seattle being played?
Venue: T-Mobile Park.
What are the opening odds for San Diego vs Seattle?
Spread: Seattle -1.5
Moneyline: San Diego +109, Seattle -128
Over/Under: 8
What are the records for San Diego vs Seattle?
San Diego: (74-57) | Seattle: (70-61)
What is the AI best bet for San Diego vs Seattle?
Remi's searched hard and found the best prop for this matchup: M. Garver over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are San Diego vs Seattle trending bets?
Both teams show healthy betting momentum, making this a competitive matchup with potential ATS opportunities on both sides.
What are San Diego trending bets?
SD trend: Entering as underdogs at +109 on the moneyline, the Padres have been a strong value pick this season, posting a solid 27–17 record against the spread.
What are Seattle trending bets?
SEA trend: Favored at –130, the Mariners have been respectable at home as chalk, going 24–20 ATS when installed as favorites.
Where can I find AI Picks for San Diego vs Seattle?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Seattle Odds
AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the San Diego vs Seattle trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
San Diego vs Seattle Opening Odds
SD Moneyline:
+109 SEA Moneyline: -128
SD Spread: +1.5
SEA Spread: -1.5
Over/Under: 8
San Diego vs Seattle Live Odds
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Seattle Mariners
Toronto Blue Jays
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Blue Jays
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O 7.5 (+126)
U 7.5 (-168)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Seattle Mariners on August 25, 2025 at T-Mobile Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |