Red Sox vs. Padres
Prediction, Odds & Props
Aug 10 | MLB AI Picks

Updated: 2025-08-08T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Sunday’s finale at Petco Park pits the Boston Red Sox against the San Diego Padres, with first pitch expected around 4:10 p.m. ET. The Padres are favored on the moneyline (around –137), with the game total set near 7.5 runs.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Aug 10, 2025

Start Time: 4:10 PM EST​

Venue: Petco Park​

Padres Record: (65-52)

Red Sox Record: (65-53)

OPENING ODDS

BOS Moneyline: +119

SD Moneyline: -142

BOS Spread: +1.5

SD Spread: -1.5

Over/Under: 8

BOS
Betting Trends

  • The Red Sox are just over .500 against the run line, covering in 49 out of 96 games (49–47).

SD
Betting Trends

  • While comprehensive ATS home data is limited, the Padres have gained betting favor since the trade deadline, with bettors backing them heavily, especially at home.

MATCHUP TRENDS

  • Boston’s solid road ATS performance contrasts with San Diego’s unmet home expectations, creating a matchup ripe for a narrow, late-inning decision decided by bullpen efficiency and clutch execution.

BOS vs. SD
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: W. Abreu over 0.5 Hits+Runs+RBI.

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Boston vs San Diego Prediction & Odds:
Free MLB Betting Insights for 8/10/25

Sunday’s interleague finale at Petco Park between the Boston Red Sox and San Diego Padres offers a compelling contrast in team identities and momentum, with Boston arriving as one of the more consistent road ATS performers this season and San Diego looking to capitalize on an upgraded roster following impactful trade deadline moves. The Red Sox bring a methodical, contact-oriented offense anchored by Alex Bregman’s disciplined approach, Jarren Duran’s speed and gap-to-gap hitting, and Rafael Devers’ ability to change the game with one swing, supported by a deep lineup that can produce runs without relying solely on the long ball, while the Padres counter with a blend of veteran presence and new firepower, headlined by Xander Bogaerts’ steady production, Fernando Tatis Jr.’s dynamic bat and athleticism, and Ryan O’Hearn’s knack for timely hits, all now reinforced by the midseason addition of elite reliever Mason Miller to stabilize the late innings.

On the mound, Boston’s probable starter will need to command the strike zone early, keep the ball down to induce grounders, and avoid falling behind against a San Diego lineup that can grind out at-bats, while the Padres’ likely starter—potentially Michael King returning from injury—will be tasked with limiting Boston’s patient hitters, preventing extended innings, and handing over a manageable game to a bullpen that’s suddenly among the league’s most intimidating. Defensively, Boston will have to play clean in the infield to erase San Diego’s speed and prevent extra 90 feet on aggressive baserunning, while the Padres must counter Boston’s small-ball tactics with sharp positioning, efficient relays, and quick double-play turns. The late-game chess match between managers Alex Cora and Mike Shildt could define the outcome, with both having the weapons to make situational substitutions, leverage platoon matchups, and squeeze maximum value out of pinch-hitters or defensive replacements. Given Petco Park’s pitcher-friendly environment, runs may be at a premium, putting even more weight on execution in situational hitting opportunities and bullpen reliability, and with Boston’s track record of covering on the road against a Padres team that has underperformed in certain home splits despite recent upgrades, this matchup has the potential to be decided by a single sequence—a well-placed hit with runners in scoring position, a clutch defensive stop in the eighth, or a high-leverage strikeout with the tying run on base—making it both a critical test of postseason readiness and a likely showcase of tight, strategic baseball in a low-scoring, high-pressure setting.

Boston Red Sox MLB Preview

The Boston Red Sox enter Sunday’s interleague finale at Petco Park with a sense of urgency and confidence, knowing that their solid record against the spread on the road has been fueled by a balanced blend of disciplined offense, dependable pitching, and opportunistic defense, and they will need all three components firing to overcome a San Diego Padres team that has upgraded its roster and gained late-season momentum. Boston’s probable starter will have to set the tone immediately by attacking the strike zone with conviction, working ahead in counts to dictate at-bats, and keeping the ball low to induce ground balls that neutralize the Padres’ power threats, especially against hitters like Fernando Tatis Jr. and Ryan O’Hearn who can change a game with one swing. Staying away from hitter’s counts will be critical, as Petco Park may suppress some home run distance but still rewards well-struck balls into the gaps, and extended innings can quickly drain a bullpen in a tight, low-scoring contest. Offensively, the Red Sox will rely on Alex Bregman’s elite plate discipline to get on base and disrupt San Diego’s pitching rhythm, Jarren Duran’s speed to create scoring chances with aggressive base running and first-to-third reads, and Rafael Devers’ ability to drive the ball to all fields to provide the type of clutch power that can decide a game where runs are scarce.

The supporting cast, including Connor Wong’s contact hitting and Ceddanne Rafaela’s knack for putting the ball in play, will be tasked with keeping innings alive and executing small-ball tactics like hit-and-run plays and sacrifice bunts to capitalize on every scoring opportunity. Defensively, Boston’s infield must be flawless in turning double plays and handling hard-hit balls cleanly, while the outfield will need to anticipate liners into the alleys and execute precise relays to cut down extra-base attempts, as the Padres are likely to challenge arms aggressively in a ballpark that encourages base stealing and aggressive running. In the bullpen, manager Alex Cora will have to be ready to make quick decisions, using his top leverage relievers in the right matchups to neutralize the heart of San Diego’s order late in the game, while also preserving flexibility in case extra innings come into play. With Petco’s layout making defensive positioning and late-game execution paramount, Boston’s ability to prevent “free 90s” through walks or defensive lapses will be just as important as their offensive output. If the starter can navigate six or more effective innings, the lineup can sustain pressure with disciplined, patient at-bats, and the bullpen delivers crisp, mistake-free work in the late innings, the Red Sox have a clear blueprint to not only win but also send a message that they can handle playoff-caliber opponents on the road, reinforcing their status as a dangerous, fundamentally sound team capable of winning in any environment.

Sunday’s finale at Petco Park pits the Boston Red Sox against the San Diego Padres, with first pitch expected around 4:10 p.m. ET. The Padres are favored on the moneyline (around –137), with the game total set near 7.5 runs. Boston vs San Diego AI Prediction: Free MLB Betting Insights for Aug 10. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Diego Padres MLB Preview

The San Diego Padres approach Sunday’s series finale at Petco Park with momentum from recent roster upgrades and the comfort of playing in front of a home crowd, aiming to close out the set against the Boston Red Sox with a performance that reinforces their playoff push and home-field advantage. Their likely starter, potentially Michael King returning from injury or another dependable rotation arm, will be tasked with setting the tone by commanding the strike zone early, using his fastball to establish counts, and mixing in breaking and offspeed pitches to disrupt the timing of Boston’s disciplined hitters like Alex Bregman, Jarren Duran, and Rafael Devers, who thrive on extending at-bats and punishing mistakes. King’s ability to pitch deep into the game while limiting baserunners will be crucial, as it allows the Padres to deploy their newly fortified bullpen—featuring high-leverage arms like Mason Miller—in optimal matchups during the late innings. Offensively, San Diego will look to Fernando Tatis Jr.’s explosiveness, Xander Bogaerts’ steady contact hitting, and Ryan O’Hearn’s clutch power to produce runs, while complementary pieces like Ha-Seong Kim and Jake Cronenworth bring versatility, patience, and speed to apply constant pressure.

The Padres’ lineup will benefit from a multi-pronged attack, blending gap-to-gap power with aggressive baserunning to take extra 90 feet whenever possible, forcing Boston’s defense to stay sharp and execute under duress. Defensively, San Diego must neutralize Boston’s small-ball tactics and opportunistic base running through sharp positioning, quick double-play turns, and accurate relays from the outfield, as preventing first-to-third advances could be the difference in a close game. Manager Mike Shildt will have to manage his bullpen with precision, mixing and matching arms based on Boston’s platoon splits and ensuring that his best strikeout relievers are lined up for the most dangerous pockets of the Red Sox lineup. Petco Park’s pitcher-friendly dimensions give the Padres some margin for error on deep fly balls, but they cannot afford defensive lapses that give Boston free baserunners, especially in a game projected to be low-scoring. If the Padres can get a quality start of six or more innings, capitalize on their offensive opportunities with runners in scoring position, and lock down the final frames with their revamped bullpen, they will be well-positioned to secure a home win that not only takes the series but also serves as a statement of their ability to handle disciplined, playoff-caliber opponents under postseason-like pressure.

Boston vs. San Diego Prop Picks (AI)

Remi is pouring through loads of datapoints on each line. In fact, anytime the Red Sox and Padres play there’s always several intriguing trends to key in on. Not to mention games played at Petco Park in Aug can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: W. Abreu over 0.5 Hits+Runs+RBI.

Boston vs. San Diego Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every past game between the Red Sox and Padres and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the growing factor knucklehead sportsbettors tend to put on Boston’s strength factors between a Red Sox team going up against a possibly deflated Padres team. It appears the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Boston vs San Diego picks, computer picks Red Sox vs Padres, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Red Sox Betting Trends

The Red Sox are just over .500 against the run line, covering in 49 out of 96 games (49–47).

Padres Betting Trends

While comprehensive ATS home data is limited, the Padres have gained betting favor since the trade deadline, with bettors backing them heavily, especially at home.

Red Sox vs. Padres Matchup Trends

Boston’s solid road ATS performance contrasts with San Diego’s unmet home expectations, creating a matchup ripe for a narrow, late-inning decision decided by bullpen efficiency and clutch execution.

Boston vs. San Diego Game Info

Boston vs San Diego starts on August 10, 2025 at 4:10 PM EST.

Spread: San Diego -1.5
Moneyline: Boston +119, San Diego -142
Over/Under: 8

Boston: (65-53)  |  San Diego: (65-52)

Remi's searched hard and found the best prop for this matchup: W. Abreu over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

Boston’s solid road ATS performance contrasts with San Diego’s unmet home expectations, creating a matchup ripe for a narrow, late-inning decision decided by bullpen efficiency and clutch execution.

BOS trend: The Red Sox are just over .500 against the run line, covering in 49 out of 96 games (49–47).

SD trend: While comprehensive ATS home data is limited, the Padres have gained betting favor since the trade deadline, with bettors backing them heavily, especially at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Boston vs. San Diego Odds

AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the Boston vs San Diego trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

Boston vs San Diego Opening Odds

BOS Moneyline: +119
SD Moneyline: -142
BOS Spread: +1.5
SD Spread: -1.5
Over/Under: 8

Boston vs San Diego Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+172
-205
+1.5 (-118)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+136
-162
+1.5 (-150)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+138
-164
+1.5 (-164)
-1.5 (+136)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-142
+1.5 (-182)
-1.5 (+150)
O 7.5 (-118)
U 7.5 (-104)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-162
+136
-1.5 (+100)
+1.5 (-120)
O 9 (+100)
U 9 (-122)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-118
-1.5 (+152)
+1.5 (-184)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Boston Red Sox vs. San Diego Padres on August 10, 2025 at Petco Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN