Reds vs Cardinals Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jun 20)

Updated: 2025-06-18T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cincinnati Reds and St. Louis Cardinals will square off at Busch Stadium on June 20, 2025, with first pitch set for 7:15 p.m. ET. St. Louis opens as a 1.5-run favorite with a –137 moneyline, while Cincinnati sits at +115, and the over/under is set at 9 runs—suggesting a closely contested game leaning slightly toward runs.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 20, 2025

Start Time: 7:15 PM EST​

Venue: Busch Stadium​

Cardinals Record: (40-35)

Reds Record: (39-36)

OPENING ODDS

CIN Moneyline: +115

STL Moneyline: -137

CIN Spread: +1.5

STL Spread: -1.5

Over/Under: 9

CIN
Betting Trends

  • The Reds are 30–27 against the run line this season and have gone 5–5 ATS in their last ten games.

STL
Betting Trends

  • The Cardinals have been favored on the moneyline 34 times this year and won 63.6% of those games; they’ve gone 6–4 ATS in their last ten matchups.

MATCHUP TRENDS

  • Cincinnati has covered the run line 4–6 in their past ten road games, while recent Reds games have gone over the total eight of the last ten—indicating a tilt toward higher scoring affairs, despite the 9-run line.

CIN vs. STL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: W. Contreras over 5.5 Fantasy Score.

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Cincinnati vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 6/20/25

Friday night’s NL Central clash between the Cincinnati Reds and the St. Louis Cardinals at Busch Stadium shapes up to be a tightly contested divisional battle with playoff implications quietly looming beneath the surface. The Cardinals, currently sitting at 37–34, have found success behind strong situational pitching, timely hitting, and a bullpen that continues to outperform expectations at home. They’ll give the ball to right-hander Andre Pallante, who enters with solid command numbers but limited length, often exiting games by the fifth inning. His role as an innings bridge means the bullpen will play a heavy part in the Cardinals’ strategy, which is a strength at Busch Stadium, where they’ve been particularly effective at closing games with a lead. Offensively, the Cardinals have taken a grind-it-out approach, relying less on the long ball and more on sequencing, walks, and contact hitting from Paul Goldschmidt, Nolan Arenado, and Brendan Donovan. Their defense is reliable, and they’ve turned in one of the lowest error rates in the league, which serves them well in close games—an area where they’ve gone 6–4 ATS in their last ten and won over 63% of games when favored by lines like –137.

On the other side, the Reds enter with a near-even overall record and a 30–27 mark against the spread, having played scrappy, competitive baseball all season. They’ll start Brady Singer, a right-hander who flashes strikeout stuff but has been prone to giving up hard contact early, particularly against patient lineups like the Cardinals’. Cincinnati’s offensive core, featuring Elly De La Cruz, Jonathan India, and Spencer Steer, has the tools to produce quickly but often relies on bursts rather than sustained offensive pressure. The Reds have hit the over in 8 of their last 10 games, a trend that reflects both increased scoring and recent bullpen fatigue, as their relief corps has been overused and inconsistent late in games. However, their defense has stayed tight, helping reduce further damage when pitchers falter. The game’s total is set at 9 runs, and that feels about right, with Cincinnati’s recent scoring trends clashing against a St. Louis team that typically keeps games close and under control. The key to the game may come in the sixth through eighth innings—if Pallante can keep the Reds off the scoreboard early and hand the ball to his bullpen with a lead, the Cardinals are well-positioned to close things out. Conversely, if Singer gets support early and Cincinnati’s offense can chase Pallante out quickly, the Reds could find themselves in position to steal a win. This feels like a one- or two-run game all the way, with final score projections hovering around 5–4 or 4–3. While St. Louis has the home-field advantage, bullpen edge, and more consistent lineup in clutch spots, Cincinnati’s recent offensive momentum and ability to hang around late make them a live dog in this divisional battle that could swing either way depending on who executes best in the middle innings.

Cincinnati Reds MLB Preview

The Cincinnati Reds head into Busch Stadium for Friday’s NL Central showdown against the St. Louis Cardinals with a resilient mindset and an underdog edge that has defined their season so far. Sporting a record hovering near .500 and a 30–27 mark against the spread, Cincinnati has consistently shown they can compete with any team, particularly when they receive early production from their offense and hold serve with their bullpen. The Reds will send right-hander Brady Singer to the mound, a starter known for his aggressive sinker-slider combination that can generate ground balls and strikeouts, but who has also been prone to early inning damage when his command falters. Singer’s ability to get through the first two trips in the lineup without giving up big innings will be critical, especially against a Cardinals offense that thrives in situational hitting and does well when working deep counts. Cincinnati’s offensive approach is built on athleticism and bursts of momentum, headlined by dynamic infielder Elly De La Cruz, who leads the team in stolen bases and extra-base hits. Jonathan India’s on-base prowess and Spencer Steer’s gap-to-gap power provide balance in the top half of the lineup, while veterans like Jeimer Candelario and Jake Fraley offer clutch potential in the middle innings.

The Reds have been scoring more of late, hitting the over in eight of their last ten games, a sign that their bats are heating up even if the bullpen has shown signs of fatigue during that stretch. Their late-inning relief arms, particularly Alexis Díaz and Lucas Sims, have been effective when not overworked, but the key for manager David Bell will be getting a clean five or six innings from Singer to avoid dipping too deep into the pen too soon. Defensively, the Reds are above average, minimizing errors and executing well on double plays—something that could neutralize the Cardinals’ contact-heavy approach if they get runners on base early. One of Cincinnati’s strengths this season has been hanging tough in games decided by two runs or fewer, reflecting a team that fights to the final out, even when trailing late. On the road, they’ve gone 4–6 against the run line in their last ten but have shown the ability to cover spreads when the offense shows up early. To come out of Busch Stadium with a win, the Reds need a combination of early pressure at the plate, aggressive baserunning, and a quality start from Singer that allows the bullpen to work in favorable matchups. This matchup may not favor them on paper, but Cincinnati has embraced its underdog identity and used it to manufacture close wins throughout the season. If their top hitters can force Cardinals starter Andre Pallante into long at-bats and capitalize on early mistakes, the Reds have a path to a 5–4 or 6–4 road victory, proving again that they’re more than just a spoiler in this divisional race—they’re a team with legitimate postseason ambition when they play to their full potential.

The Cincinnati Reds and St. Louis Cardinals will square off at Busch Stadium on June 20, 2025, with first pitch set for 7:15 p.m. ET. St. Louis opens as a 1.5-run favorite with a –137 moneyline, while Cincinnati sits at +115, and the over/under is set at 9 runs—suggesting a closely contested game leaning slightly toward runs. Cincinnati vs St. Louis AI Prediction: Free MLB Betting Insights for Jun 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

St. Louis Cardinals MLB Preview

The St. Louis Cardinals return home to Busch Stadium on June 20 to begin a key NL Central matchup against the Cincinnati Reds, looking to maintain their upward momentum and build upon their respectable 37–34 record. St. Louis has steadied itself in the standings by leaning on consistency, depth, and a return to form from several core players, particularly in the pitching department. Andre Pallante is slated to take the mound Friday and brings with him a repertoire built around ground ball induction and efficient pitch counts, though his average start typically stretches only four to five innings. That makes the Cardinals’ bullpen a critical piece of the puzzle—thankfully, this is a group that’s been performing solidly in late innings, particularly in close home games, where the unit thrives under pressure with defined roles and dependable arms like Ryan Helsley and Giovanny Gallegos anchoring the backend. Defensively, St. Louis has long been among the most fundamentally sound teams in the league, and this season has been no different, with a low error rate and effective double-play execution giving them an edge in tight games where one missed grounder can change the outcome. Offensively, the Cardinals aren’t overpowering, but they’re methodical and efficient. Paul Goldschmidt and Nolan Arenado continue to be cornerstones in the middle of the lineup, while Brendan Donovan and Lars Nootbaar contribute with timely hits and strong on-base skills.

While power numbers have been modest, the team excels at stringing together base hits and situational production—sacrifice flies, hit-and-run plays, and well-placed contact that pressures opposing infields. At Busch Stadium, the Cardinals have gone 6–4 ATS over their last 10 games and have won nearly two-thirds of their games when favored by moneylines similar to Friday’s –137 line, reflecting their ability to protect home turf in winnable spots. They’ll be facing Reds starter Brady Singer, a pitcher who can be vulnerable early if hitters show patience and discipline, something St. Louis’s lineup has been trending toward over the past two weeks. The Cardinals will aim to force Singer into high pitch counts early, setting the table for their deeper, more dependable bullpen to control the middle and late innings. Offensively, this game could be determined by how well Goldschmidt and Arenado handle Singer’s off-speed stuff and whether the bottom half of the order can chip in enough to push the Reds’ relievers into action before the seventh. In games like this—closely lined, with a total set at 9—St. Louis has often succeeded by avoiding big mistakes, playing station-to-station baseball, and letting their bullpen slam the door late. If Pallante can limit the Reds to two or three runs through five innings and the Cardinals avoid stranding runners in scoring position, they’re well-positioned to grind out a 4–3 or 5–4 home win. With the division still up for grabs and every series mattering more in late June, the Cardinals know the formula for success: pitch to contact, play clean defense, capitalize with runners on, and trust their relievers to carry them the rest of the way.

Cincinnati vs. St. Louis Prop Picks (AI)

AI algorithm Remi is pouring through mountains of data on each team. In fact, anytime the Reds and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at Busch Stadium in Jun rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: W. Contreras over 5.5 Fantasy Score.

Cincinnati vs. St. Louis Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Reds and Cardinals and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

Remi has been most focused on the trending emphasis human bettors often put on St. Louis’s strength factors between a Reds team going up against a possibly deflated Cardinals team. It appears the true game analytics appear to reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cincinnati vs St. Louis picks, computer picks Reds vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/20 SEA@TOR UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/20 SEA@TOR UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Reds Betting Trends

The Reds are 30–27 against the run line this season and have gone 5–5 ATS in their last ten games.

Cardinals Betting Trends

The Cardinals have been favored on the moneyline 34 times this year and won 63.6% of those games; they’ve gone 6–4 ATS in their last ten matchups.

Reds vs. Cardinals Matchup Trends

Cincinnati has covered the run line 4–6 in their past ten road games, while recent Reds games have gone over the total eight of the last ten—indicating a tilt toward higher scoring affairs, despite the 9-run line.

Cincinnati vs. St. Louis Game Info

Cincinnati vs St. Louis starts on June 20, 2025 at 7:15 PM EST.

Spread: St. Louis -1.5
Moneyline: Cincinnati +115, St. Louis -137
Over/Under: 9

Cincinnati: (39-36)  |  St. Louis: (40-35)

Remi's searched hard and found the best prop for this matchup: W. Contreras over 5.5 Fantasy Score.. Prices move—always shop for the best number.

Cincinnati has covered the run line 4–6 in their past ten road games, while recent Reds games have gone over the total eight of the last ten—indicating a tilt toward higher scoring affairs, despite the 9-run line.

CIN trend: The Reds are 30–27 against the run line this season and have gone 5–5 ATS in their last ten games.

STL trend: The Cardinals have been favored on the moneyline 34 times this year and won 63.6% of those games; they’ve gone 6–4 ATS in their last ten matchups.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cincinnati vs. St. Louis Odds

AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Cincinnati vs St. Louis trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.

Cincinnati vs St. Louis Opening Odds

CIN Moneyline: +115
STL Moneyline: -137
CIN Spread: +1.5
STL Spread: -1.5
Over/Under: 9

Cincinnati vs St. Louis Live Odds

Games PTS ML SPR O/U
Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
-140
+127
-1.5 (+124)
+1.5 (-140)
O 7.5 (+107)
U 7.5 (-123)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cincinnati Reds vs. St. Louis Cardinals on June 20, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN