White Sox vs. Astros
Prediction, Odds & Props
Jun 12 | MLB AI Picks
Updated: 2025-06-10T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On June 12, 2025, the Chicago White Sox and Houston Astros will face off at Daikin Park as both teams close out their three-game set. The Astros look to solidify their position in the AL West playoff race, while the White Sox continue seeking consistency and growth during a difficult rebuilding campaign.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jun 12, 2025
Start Time: 8:10 PM EST
Venue: Daikin Park
Astros Record: (37-30)
White Sox Record: (23-35)
OPENING ODDS
CHW Moneyline: +213
HOU Moneyline: -263
CHW Spread: +1.5
HOU Spread: -1.5
Over/Under: 7.5
CHW
Betting Trends
- The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.
HOU
Betting Trends
- The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.
MATCHUP TRENDS
- The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.
CHW vs. HOU
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Melton over 3.5 Fantasy Score.
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Chicago White Sox vs Houston Prediction & Odds:
Free MLB Betting Insights for 6/12/25
Meanwhile, the Chicago White Sox arrive at 23–44 with a roster in flux, trying to string together competitive innings behind emerging young contributors and a reshaped identity. While their season has been a tough grind, the Sox have managed to cover the spread in five of their last seven games and have shown more fight in recent matchups. Miguel Vargas leads the team in power with nine home runs and 30 RBIs, showing the potential to be a middle-of-the-order presence in the years ahead. Chase Meidroth has become a spark plug at the top of the order, batting .296 with a .383 on-base percentage, providing rare consistency in an otherwise unpredictable lineup. On the mound, Davis Martin (2–6, 3.62 ERA) has pitched better than his record suggests, but a lack of support and inconsistent defense has often worked against him. The bullpen remains a weakness, with command issues and defensive lapses often turning close games into losses. On the road, the White Sox have been particularly vulnerable, with a dismal 6–26 record away from Guaranteed Rate Field. Against an Astros club that is deep, disciplined, and confident at home, Chicago will need flawless execution, early run support, and a standout start from Martin to even keep this game close. All signs point to Houston having the upper hand, with their depth, pitching, and run-scoring potential creating a wide performance gap, but for the White Sox, the focus is on development, finding positives, and turning individual progress into future wins. A sweep would push Houston further up the AL West while further exposing Chicago’s need for patience and continued investment in young talent.
Miguel Vargas. Are you kidding?! 🤯 pic.twitter.com/TVbNzCtdE1
— Chicago White Sox (@whitesox) June 12, 2025
Chicago White Sox White Sox MLB Preview
The Chicago White Sox enter their June 12, 2025 matchup against the Houston Astros with a 23–44 record and the sobering realization that their season has transitioned from contention to development mode. Amid a challenging campaign, the White Sox have turned their attention to identifying core players for the future and building from a young, evolving roster. Offensively, Miguel Vargas has emerged as the team’s most dangerous power threat, leading the club with nine home runs and 30 RBIs. His raw strength and ability to drive the ball to all fields have given the White Sox a presence in the middle of the order, while Chase Meidroth continues to build on a breakout season at the top of the lineup, boasting a .296 batting average and an impressive .383 on-base percentage. Meidroth’s consistency and plate discipline have been rare bright spots in a lineup that otherwise lacks reliable production. Though the White Sox have struggled to string hits together and execute with runners in scoring position, they’ve managed to cover the spread in five of their last seven games, indicating competitive spurts and tighter losses as young talent gains more experience. On the pitching side, Davis Martin gets the nod in the series finale and enters with a 2–6 record and 3.62 ERA—respectable numbers when considering the lack of offensive support and the burden placed on him to be efficient in nearly every outing.
Martin has shown flashes of command and poise, often working through tough spots without imploding, but he’s also been the victim of poor defensive support behind him, which has inflated his workload and ERA in high-leverage innings. The bullpen behind him has been erratic and remains one of the weakest units in the league, lacking reliable setup arms and often faltering in late-game situations when the White Sox have been within striking distance. Defensively, the White Sox have struggled to play clean baseball, and errors have routinely turned manageable innings into extended threats for opposing lineups. Their 6–26 road record reflects both execution issues and a general lack of momentum when playing away from home, where they’ve failed to establish any sort of identity or rhythm. As they face the Astros—one of the league’s most balanced and well-prepared teams—the White Sox must look to capitalize on early opportunities at the plate and hope for a standout start from Martin to keep the game from getting out of hand. If Vargas and Meidroth can reach base and ignite rallies, and if Martin can avoid giving up early runs, they may have a shot to stay close. But in reality, the White Sox remain an underdog, and while the focus for 2025 may already be shifting to long-term development, games like these provide valuable tests for their rising players. Even in losses, moments of individual progress can serve as foundational blocks for the seasons ahead, especially as Chicago seeks to reestablish itself as a serious threat in the American League.

Credit: USA TODAY/IMAGN
Houston Astros MLB Preview
The Houston Astros return to Daikin Park on June 12, 2025, to close out their three-game series against the Chicago White Sox with a 36–30 record and a clear opportunity to complete the sweep and build further momentum in the AL West. Sitting just behind the division leaders, the Astros have been rounding into form in all facets—offensively, defensively, and on the mound—thanks in large part to a roster that blends experience with emerging consistency. Jeremy Peña has quietly been one of the most productive shortstops in the league this season, hitting .319 with timely extra-base hits and reliable defense, while Isaac Paredes has offered middle-of-the-order muscle with a .457 slugging percentage and consistent RBI production. The return of key bats like Jose Altuve and Yordan Álvarez has deepened the lineup, giving the Astros a level of firepower that forces pitchers to battle from the first inning on. Starting pitcher Framber Valdez gets the nod in the finale and enters with a 6–4 record and a strong 3.07 ERA, using pinpoint command and a devastating curveball to stifle both right- and left-handed hitters. Valdez has helped stabilize the rotation, which earlier this year faced injuries and inconsistency, and he’s been especially effective at home, where he’s kept hard contact to a minimum and regularly worked deep into games.
Behind him, the bullpen has been one of the best in baseball over the past month, led by Josh Hader, who has locked down the closer role with a 1.29 ERA and an elite strikeout rate. Houston has won 15 of its last 22 games against the spread and is covering at a high clip when Valdez starts, underlining their growing dominance when playing to potential. Their home record now sits at an impressive 22–13, built largely on their ability to take early leads and protect them with smart bullpen management and clean defense. Manager Joe Espada has done a stellar job of rotating players to keep the roster fresh while continuing to emphasize smart baserunning and situational hitting. Against a struggling White Sox team that is 6–26 on the road and prone to defensive breakdowns, the Astros will look to apply pressure early, work long counts, and capitalize on any miscues. Houston knows that every win against sub-.500 competition is vital in a tight playoff race, and with a complete roster and Valdez on the mound, they are well-positioned to close out this series with another win. A sweep here would extend Houston’s climb up the standings, continue their strong June play, and reinforce their identity as a veteran team built not only to win in the regular season but to contend deep into October. For the Astros, this is not just a series finale—it’s an opportunity to sharpen their edge and keep the pressure on their AL West rivals.
Walk it like an All-Star.@budweiserusa ⭐️ https://t.co/W06pfHQMR1 pic.twitter.com/jixidkL8Ux
— Houston Astros (@astros) June 12, 2025
Chicago White Sox vs. Houston Prop Picks (AI)
Chicago White Sox vs. Houston Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every angle between the White Sox and Astros and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of factor human bettors regularly put on coaching factors between a White Sox team going up against a possibly healthy Astros team. In reality, the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Chicago White Sox vs Houston picks, computer picks White Sox vs Astros, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
White Sox Betting Trends
The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.
Astros Betting Trends
The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.
White Sox vs. Astros Matchup Trends
The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.
Chicago White Sox vs. Houston Game Info
What time does Chicago White Sox vs Houston start on June 12, 2025?
Chicago White Sox vs Houston starts on June 12, 2025 at 8:10 PM EST.
Where is Chicago White Sox vs Houston being played?
Venue: Daikin Park.
What are the opening odds for Chicago White Sox vs Houston?
Spread: Houston -1.5
Moneyline: Chicago White Sox +213, Houston -263
Over/Under: 7.5
What are the records for Chicago White Sox vs Houston?
Chicago White Sox: (23-35) | Houston: (37-30)
What is the AI best bet for Chicago White Sox vs Houston?
Remi's searched hard and found the best prop for this matchup: J. Melton over 3.5 Fantasy Score.. Prices move—always shop for the best number.
What are Chicago White Sox vs Houston trending bets?
The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.
What are Chicago White Sox trending bets?
CHW trend: The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.
What are Houston trending bets?
HOU trend: The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.
Where can I find AI Picks for Chicago White Sox vs Houston?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White Sox vs. Houston Odds
Remi is pouring through loads of data points on each team. In fact, anytime the Chicago White Sox vs Houston trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.
Chicago White Sox vs Houston Opening Odds
CHW Moneyline:
+213 HOU Moneyline: -263
CHW Spread: +1.5
HOU Spread: -1.5
Over/Under: 7.5
Chicago White Sox vs Houston Live Odds
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Oct 2, 2025 3:08PM EDT
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Cleveland Guardians
10/2/25 3:08PM
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Guardians
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–
–
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-102
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-1.5 (+172)
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O 7 (-105)
U 7 (-115)
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–
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+100
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-1.5 (+172)
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O 7.5 (-110)
U 7.5 (-110)
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Red Sox
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–
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+136
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+1.5 (-160)
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O 7.5 (-120)
U 7.5 (-102)
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Oct 4, 2025 2:30PM EDT
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–
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+110
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pk
pk
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Oct 4, 2025 5:09PM EDT
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Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
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–
–
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+108
-126
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pk
pk
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O 7 (-134)
U 7 (+117)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago White Sox White Sox vs. Houston Astros on June 12, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |