White Sox vs. Astros
Prediction, Odds & Props
Jun 12 | MLB AI Picks

Updated: 2025-06-10T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On June 12, 2025, the Chicago White Sox and Houston Astros will face off at Daikin Park as both teams close out their three-game set. The Astros look to solidify their position in the AL West playoff race, while the White Sox continue seeking consistency and growth during a difficult rebuilding campaign.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 12, 2025

Start Time: 8:10 PM EST​

Venue: Daikin Park​

Astros Record: (37-30)

White Sox Record: (23-35)

OPENING ODDS

CHW Moneyline: +213

HOU Moneyline: -263

CHW Spread: +1.5

HOU Spread: -1.5

Over/Under: 7.5

CHW
Betting Trends

  • The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.

HOU
Betting Trends

  • The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.

MATCHUP TRENDS

  • The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.

CHW vs. HOU
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Melton over 3.5 Fantasy Score.

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
310-227
VAULT
NET UNITS
(INCL VIG)
+390.9
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$39,086
EXECUTIVE
VS. SPREAD
1564-1335
EXECUTIVE
NET UNITS
(INCL VIG)
+387.3
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$38,728

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Chicago White Sox vs Houston Prediction & Odds:
Free MLB Betting Insights for 6/12/25

The June 12, 2025 matchup between the Chicago White Sox and the Houston Astros at Daikin Park wraps up a three-game series between two teams at opposite ends of the competitive spectrum, with Houston chasing postseason positioning and the White Sox navigating a season of developmental growing pains. The Astros enter the finale with a 36–30 record and looking to complete a sweep after winning the first two games of the series, leaning heavily on their home-field advantage and consistent veteran contributions. Houston’s offense has been spearheaded by Jeremy Peña, who is hitting .319 with a strong approach at the plate, and Isaac Paredes, who brings slugging ability to the middle of the lineup and continues to drive in timely runs. Their pitching staff has been a key strength, anchored by lefty Framber Valdez, who is expected to start the finale with a 6–4 record and 3.07 ERA. Valdez’s ability to limit hard contact and generate ground balls fits perfectly with Houston’s defensive system, which has been sharper over the past few weeks. The Astros’ bullpen is one of the best in baseball, led by elite closer Josh Hader and his 1.29 ERA, supported by strong setup arms that consistently bridge the gap from starter to ninth inning without giving opponents many opportunities to rally. Houston’s recent form includes 15 covers against the spread over their last 22 games, including four straight when Valdez starts, reinforcing their ability to control games and win with margin.

Meanwhile, the Chicago White Sox arrive at 23–44 with a roster in flux, trying to string together competitive innings behind emerging young contributors and a reshaped identity. While their season has been a tough grind, the Sox have managed to cover the spread in five of their last seven games and have shown more fight in recent matchups. Miguel Vargas leads the team in power with nine home runs and 30 RBIs, showing the potential to be a middle-of-the-order presence in the years ahead. Chase Meidroth has become a spark plug at the top of the order, batting .296 with a .383 on-base percentage, providing rare consistency in an otherwise unpredictable lineup. On the mound, Davis Martin (2–6, 3.62 ERA) has pitched better than his record suggests, but a lack of support and inconsistent defense has often worked against him. The bullpen remains a weakness, with command issues and defensive lapses often turning close games into losses. On the road, the White Sox have been particularly vulnerable, with a dismal 6–26 record away from Guaranteed Rate Field. Against an Astros club that is deep, disciplined, and confident at home, Chicago will need flawless execution, early run support, and a standout start from Martin to even keep this game close. All signs point to Houston having the upper hand, with their depth, pitching, and run-scoring potential creating a wide performance gap, but for the White Sox, the focus is on development, finding positives, and turning individual progress into future wins. A sweep would push Houston further up the AL West while further exposing Chicago’s need for patience and continued investment in young talent.

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter their June 12, 2025 matchup against the Houston Astros with a 23–44 record and the sobering realization that their season has transitioned from contention to development mode. Amid a challenging campaign, the White Sox have turned their attention to identifying core players for the future and building from a young, evolving roster. Offensively, Miguel Vargas has emerged as the team’s most dangerous power threat, leading the club with nine home runs and 30 RBIs. His raw strength and ability to drive the ball to all fields have given the White Sox a presence in the middle of the order, while Chase Meidroth continues to build on a breakout season at the top of the lineup, boasting a .296 batting average and an impressive .383 on-base percentage. Meidroth’s consistency and plate discipline have been rare bright spots in a lineup that otherwise lacks reliable production. Though the White Sox have struggled to string hits together and execute with runners in scoring position, they’ve managed to cover the spread in five of their last seven games, indicating competitive spurts and tighter losses as young talent gains more experience. On the pitching side, Davis Martin gets the nod in the series finale and enters with a 2–6 record and 3.62 ERA—respectable numbers when considering the lack of offensive support and the burden placed on him to be efficient in nearly every outing.

Martin has shown flashes of command and poise, often working through tough spots without imploding, but he’s also been the victim of poor defensive support behind him, which has inflated his workload and ERA in high-leverage innings. The bullpen behind him has been erratic and remains one of the weakest units in the league, lacking reliable setup arms and often faltering in late-game situations when the White Sox have been within striking distance. Defensively, the White Sox have struggled to play clean baseball, and errors have routinely turned manageable innings into extended threats for opposing lineups. Their 6–26 road record reflects both execution issues and a general lack of momentum when playing away from home, where they’ve failed to establish any sort of identity or rhythm. As they face the Astros—one of the league’s most balanced and well-prepared teams—the White Sox must look to capitalize on early opportunities at the plate and hope for a standout start from Martin to keep the game from getting out of hand. If Vargas and Meidroth can reach base and ignite rallies, and if Martin can avoid giving up early runs, they may have a shot to stay close. But in reality, the White Sox remain an underdog, and while the focus for 2025 may already be shifting to long-term development, games like these provide valuable tests for their rising players. Even in losses, moments of individual progress can serve as foundational blocks for the seasons ahead, especially as Chicago seeks to reestablish itself as a serious threat in the American League.

On June 12, 2025, the Chicago White Sox and Houston Astros will face off at Daikin Park as both teams close out their three-game set. The Astros look to solidify their position in the AL West playoff race, while the White Sox continue seeking consistency and growth during a difficult rebuilding campaign. Chicago White Sox vs Houston AI Prediction: Free MLB Betting Insights for Jun 12. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Houston Astros MLB Preview

The Houston Astros return to Daikin Park on June 12, 2025, to close out their three-game series against the Chicago White Sox with a 36–30 record and a clear opportunity to complete the sweep and build further momentum in the AL West. Sitting just behind the division leaders, the Astros have been rounding into form in all facets—offensively, defensively, and on the mound—thanks in large part to a roster that blends experience with emerging consistency. Jeremy Peña has quietly been one of the most productive shortstops in the league this season, hitting .319 with timely extra-base hits and reliable defense, while Isaac Paredes has offered middle-of-the-order muscle with a .457 slugging percentage and consistent RBI production. The return of key bats like Jose Altuve and Yordan Álvarez has deepened the lineup, giving the Astros a level of firepower that forces pitchers to battle from the first inning on. Starting pitcher Framber Valdez gets the nod in the finale and enters with a 6–4 record and a strong 3.07 ERA, using pinpoint command and a devastating curveball to stifle both right- and left-handed hitters. Valdez has helped stabilize the rotation, which earlier this year faced injuries and inconsistency, and he’s been especially effective at home, where he’s kept hard contact to a minimum and regularly worked deep into games.

Behind him, the bullpen has been one of the best in baseball over the past month, led by Josh Hader, who has locked down the closer role with a 1.29 ERA and an elite strikeout rate. Houston has won 15 of its last 22 games against the spread and is covering at a high clip when Valdez starts, underlining their growing dominance when playing to potential. Their home record now sits at an impressive 22–13, built largely on their ability to take early leads and protect them with smart bullpen management and clean defense. Manager Joe Espada has done a stellar job of rotating players to keep the roster fresh while continuing to emphasize smart baserunning and situational hitting. Against a struggling White Sox team that is 6–26 on the road and prone to defensive breakdowns, the Astros will look to apply pressure early, work long counts, and capitalize on any miscues. Houston knows that every win against sub-.500 competition is vital in a tight playoff race, and with a complete roster and Valdez on the mound, they are well-positioned to close out this series with another win. A sweep here would extend Houston’s climb up the standings, continue their strong June play, and reinforce their identity as a veteran team built not only to win in the regular season but to contend deep into October. For the Astros, this is not just a series finale—it’s an opportunity to sharpen their edge and keep the pressure on their AL West rivals.

Chicago White Sox vs. Houston Prop Picks (AI)

AI algorithm Remi is pouring through loads of datapoints on each player. In fact, anytime the White Sox and Astros play there’s always several intriguing angles to key in on. Not to mention games played at Daikin Park in Jun almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Melton over 3.5 Fantasy Score.

Chicago White Sox vs. Houston Prediction (AI)

Remi Robot Icon

Remi, our AI sports genius, has been pouring over millions of data from every angle between the White Sox and Astros and using recursive machine learning and impressive AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of factor human bettors regularly put on coaching factors between a White Sox team going up against a possibly healthy Astros team. In reality, the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Chicago White Sox vs Houston picks, computer picks White Sox vs Astros, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 10/1 SD@CHC UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
MLB 10/1 CIN@LAD UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/1 DET@CLE UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 BOS@NYY UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 10/1 CIN@LAD GET FREE PICK NOW 1
MLB 10/1 BOS@NYY UNLOCK THIS PICK 0 INTEL Locked INTEL
MLB 10/1 BOS@NYY GET FREE PICK NOW 0

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

White Sox Betting Trends

The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.

Astros Betting Trends

The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.

White Sox vs. Astros Matchup Trends

The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.

Chicago White Sox vs. Houston Game Info

Chicago White Sox vs Houston starts on June 12, 2025 at 8:10 PM EST.

Spread: Houston -1.5
Moneyline: Chicago White Sox +213, Houston -263
Over/Under: 7.5

Chicago White Sox: (23-35)  |  Houston: (37-30)

Remi's searched hard and found the best prop for this matchup: J. Melton over 3.5 Fantasy Score.. Prices move—always shop for the best number.

The Astros have covered the run line in four consecutive starts by Framber Valdez, their projected starter for this matchup.

CHW trend: The White Sox have covered the spread in five of their last seven games, showing signs of competitiveness despite their struggles.

HOU trend: The Astros have covered the spread in 15 of their last 22 games, reflecting strong form and the ability to win convincingly at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago White Sox vs. Houston Odds

Remi is pouring through loads of data points on each team. In fact, anytime the Chicago White Sox vs Houston trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.

Chicago White Sox vs Houston Opening Odds

CHW Moneyline: +213
HOU Moneyline: -263
CHW Spread: +1.5
HOU Spread: -1.5
Over/Under: 7.5

Chicago White Sox vs Houston Live Odds

Games PTS ML SPR O/U
Oct 2, 2025 3:08PM EDT
Detroit Tigers
Cleveland Guardians
10/2/25 3:08PM
Tigers
Guardians
-102
-116
-1.5 (+172)
+1.5 (-210)
O 7 (-105)
U 7 (-115)
Oct 2, 2025 5:08PM EDT
San Diego Padres
Chicago Cubs
10/2/25 5:08PM
Padres
Cubs
+100
-118
-1.5 (+172)
+1.5 (-210)
O 7.5 (-110)
U 7.5 (-110)
Oct 2, 2025 8:08PM EDT
Boston Red Sox
New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
+136
-162
+1.5 (-160)
-1.5 (+130)
O 7.5 (-120)
U 7.5 (-102)
Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
+110
-130
pk
pk
Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
+108
-126
pk
pk
O 7 (-134)
U 7 (+117)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago White Sox White Sox vs. Houston Astros on June 12, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS